Mitochondrial biogenesis in the axons of vertebrate peripheral neurons

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Developmental Neurobiology

• Publication date

  2008-09-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/dneu.20668PMID 18666204PMCID PMC2538952
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Axon Viability and Mitochondrial Function are Dependent on Local Protein Synthesis in Sympathetic Neurons

  2007cited by this paper
• The machines that divide and fuse mitochondria

  2007influential reference
• New Insights into Neuronal Regeneration: The Role of Axonal Protein Synthesis in Pathfinding and Axonal Extension

  2006cited by this paper
• Differences in mitochondrial movement and morphology in young and mature primary cortical neurons in culture.

  2006cited by this paper
• Asymmetrical β-actin mRNA translation in growth cones mediates attractive turning to netrin-1

  2006cited by this paper
• Mitochondrial fusion and fission in mammals.

  2006cited by this paper
• The axonal transport of mitochondria

  2005cited by this paper
• Axonal Protein Synthesis and Degradation Are Necessary for Efficient Growth Cone Regeneration

  2005cited by this paper
• The mitochondrial protein MTP18 contributes to mitochondrial fission in mammalian cells

  2005influential reference
• Mitochondria form a filamentous reticular network in hippocampal dendrites but are present as discrete bodies in axons: A three‐dimensional ultrastructural study

  2005cited by this paper
• Disruption of Fusion Results in Mitochondrial Heterogeneity and Dysfunction*

  2005cited by this paper
• Unscheduled DNA synthesis: a functional assay for global genomic nucleotide excision repair.

  2005cited by this paper
• Mitochondrial accumulation in the distal part of the initial segment of chicken spinal motoneurons.

  2004cited by this paper
• Mitochondrial movement and positioning in axons: the role of growth factor signaling

  2003cited by this paper
• Organization and translation of mRNA in sympathetic axons

  2003influential reference
• Replication of mitochondrial DNA occurs throughout the mitochondria of cultured human cells.

  2003influential reference
• Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells

  2003influential reference
• Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA.

  2003cited by this paper
• Transfection of primary central and peripheral nervous system neurons by electroporation.

  2003cited by this paper
• Response of Mitochondrial Traffic to Axon Determination and Differential Branch Growth

  2003cited by this paper
• Adaptation in the chemotactic guidance of nerve growth cones

  2002cited by this paper
• Axonal Self-Destruction and Neurodegeneration

  2002cited by this paper
• Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA

  2002cited by this paper
• The distribution of mitochondrial activity in relation to optic nerve structure.

  2002cited by this paper
• A Functional Role for Intra-Axonal Protein Synthesis during Axonal Regeneration from Adult Sensory Neurons

  2001cited by this paper
• Local synthesis of nuclear‐encoded mitochondrial proteins in the presynaptic nerve terminal

  2001cited by this paper
• Mitochondrial filaments and clusters as intracellular power-transmitting cables.

  2001cited by this paper
• Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation.

  2001cited by this paper
• Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells.

  2001influential reference
• HIV neuropathy: Insights in the pathology of HIV peripheral nerve disease

  2001cited by this paper
• Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria

  2001cited by this paper
• Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria

  2001cited by this paper
• Protein synthesis in axons and terminals: significance for maintenance, plasticity and regulation of phenotype. With a critique of slow transport theory.

  2000cited by this paper
• Mitochondria and neuronal survival.

  2000cited by this paper
• A Mitochondrial Division Apparatus Takes Shape

  2000cited by this paper
• In Vivo Functional Analysis of the Human Mitochondrial DNA Polymerase POLG Expressed in Cultured Human Cells*

  2000cited by this paper
• A Mitochondrial Division Apparatus Takes Shape

  2000cited by this paper
• Age-related changes of DNA repair and mitochondrial DNA synthesis in the mouse brain

  1999cited by this paper
• C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane.

  1999influential reference
• Protein-synthesizing machinery in the axon compartment.

  1999cited by this paper
• The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast

  1999influential reference
• Division versus Fusion: Dnm1p and Fzo1p Antagonistically Regulate Mitochondrial Shape

  1999cited by this paper
• Changes in Mitochondrial Function Resulting from Synaptic Activity in the Rat Hippocampal Slice

  1998cited by this paper
• Protein synthesizing units in presynaptic and postsynaptic domains of squid neurons.

  1998cited by this paper
• Unscheduled DNA synthesis and mitochondrial DNA synthetic rate following injury of the facial nerve

  1997cited by this paper
• Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database.

  1997cited by this paper
• Protein import into mitochondria.

  1997cited by this paper
• Insensitivity of cultured rat cortical neurons to mitochondrial DNA synthesis inhibitors: evidence for a slow turnover of mitochondrial DNA.

  1997cited by this paper
• In situ localization of mitochondrial DNA replication in intact mammalian cells

  1996cited by this paper
• Localization and active transport of mRNA in axons of sympathetic neurons in culture

  1996cited by this paper
• Compartmentalization of Autocrine Signal Transduction Pathways in Sis-transformed NIH 3T3 Cells (*)

  1995cited by this paper
• Efficient Incorporation of Anti-HIV Deoxynucleotides by Recombinant Yeast Mitochondrial DNA Polymerase (*)

  1995cited by this paper
• Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons

  1995cited by this paper
• Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion.

  1994cited by this paper
• 2',3'-Dideoxycytidine alters calcium buffering in cultured dorsal root ganglion neurons.

  1994cited by this paper
• Molecular dissection of the myelinated axon

  1993cited by this paper
• Axoplasmic organelles at nodes of Ranvier. I. Occurrence and distribution in large myelinated spinal root axons of the adult cat

  1993cited by this paper
• The regulation of bidirectional mitochondrial transport is coordinated with axonal outgrowth.

  1993cited by this paper
• Mitochondrial cytopathies.

  1993cited by this paper
• Products of endocytosis and autophagy are retrieved from axons by regulated retrograde organelle transport

  1993cited by this paper
• An integrated theory of aging as the result of mitochondrial-DNA mutation in differentiated cells.

  1991cited by this paper
• Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.

  1991influential reference
• Evaluation of local synthesis of axonal proteins in the goldfish Mauthner cell axon and axons of dorsal and ventral roots of the rat in vitro.

  1991cited by this paper
• Reversible axonal neuropathy from the treatment of AIDS and related disorders with 2′,3′‐dideoxycytidine (ddc)

  1989cited by this paper
• Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases.

  1989cited by this paper
• Hypothesis. Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases

  1989cited by this paper
• Studies on the inhibition of mitochondrial DNA replication by 3'-azido-3'-deoxythymidine and other dideoxynucleoside analogs which inhibit HIV-1 replication.

  1989cited by this paper
• The spectrum of peripheral neuropathy associated with ARC and AIDS

  1988cited by this paper
• Abnormalities of peripheral nerve in patients with human immunodeficiency virus infection

  1988cited by this paper
• Histochemical localization of cytochrome oxidase in the hippocampus: correlation with specific neuronal types and afferent pathways.

  1982cited by this paper
• Histochemical changes in cytochrome oxidase of cortical barrels after vibrissal removal in neonatal and adult mice.

  1980cited by this paper
• Axonal transport.

  1976cited by this paper
• The turnover of mitochondria in a variety of tissues of young adult and aged rats.

  1971cited by this paper
• Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat.

  1969cited by this paper
• Ageing and degenerative diseases

  1945influential reference

• Mitochondrial quality in aging and neurodegeneration: The emerging role of mitochondria-derived vesicles.

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• Mitochondria in aging and age-associated diseases.

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• Mitochondrial dynamics reveal potential to facilitate axonal regeneration after spinal cord injury

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• The yin and yang of neuronal mitophagy: physiological functions and pathological implications in neurodevelopmental disorders

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• Impact of Ageing and Disuse on Neuromuscular Junction and Mitochondrial Function and Morphology: Current Evidence and Controversies.

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• A detailed review of pharmacology of MFN1 (mitofusion-1)-mediated mitochondrial dynamics: Implications for cellular health and diseases

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• How neurons maintain their axons long-term: an integrated view of axon biology and pathology

  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2022cites this paper
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• The impact of diet upon mitochondrial physiology (Review)

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• Restoration of mitochondria axonal transport by adaptor Disc1 supplementation prevents neurodegeneration and rescues visual function.

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• Mitochondrial protein dysfunction in pathogenesis of neurological diseases

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• Mitochondrial behavior when things go wrong in the axon

  2022cites this paper
• Casein Kinase 2 Signaling in White Matter Stroke

  2022cites this paper
• Mitochondrial complementation occurs in rat hippocampal axons and supports the synaptic vesicle cycle

  2022cites this paper
• Dendrite architecture determines mitochondrial distribution patterns in vivo

  2022cites this paper
• Oxidative phosphorylation mediated pathogenesis of Parkinson's disease and its implication via Akt signaling.

  2022cites this paper
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  2022cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
• Mitochondrial transport serves as a mitochondrial quality control strategy in axons: Implications for central nervous system disorders

  2019cites this paper
• Neurotrophins induce fission of mitochondria along embryonic sensory axons

  2019cites this paper
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  2019cites this paper
• Prokaryotic SPHINX replication sequences are conserved in mammalian brain and participate in neurodegeneration

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018influential citation
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
• Mitochondrial dynamics in demyelinated axons in a cerebellar slice culture system

  2018cites this paper
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  2018cites this paper
• The role of mitochondria in axon development and regeneration

  2018cites this paper
• Mitochondria at the neuronal presynapse in health and disease

  2018cites this paper
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  2018cites this paper
• Axonal transport deficits in multiple sclerosis: spiraling into the abyss

  2017cites this paper
• Mitochondrial health maintenance in axons.

  2017cites this paper
• Bardoxolone methyl for the prevention of obesity focusing on the pathology of gut-brain-adipose axis

  2017cites this paper
• α-Synuclein pathology and mitochondrial dysfunction: Studies in cell models for Parkinson’s disease

  2017cites this paper
• An emerging role for mitochondrial dynamics in schizophrenia.

  2017cites this paper
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  2017cites this paper
• Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties

  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
• Mitochondrial dynamics, transport, and quality control: A bottleneck for retinal ganglion cell viability in optic neuropathies.

  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
• The Concerted Action of Mitochondrial Dynamics and Positioning: New Characters in Cancer Onset and Progression

  2017cites this paper
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  2017cites this paper
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  2017cites this paper
• α-Synuclein pathology and mitochondrial dysfunction

  2017cites this paper
• α-Synuclein pathology and mitochondrial dysfunction

  2017cites this paper
• α-Synuclein pathology and mitochondrial dysfunction

  2017cites this paper
• Analysis of mitochondrial organization and function in the Drosophila blastoderm embryo

  2017cites this paper
• α-Synuclein pathology and mitochondrial dysfunction

  2017cites this paper
• Iron Homeostasis in Neuron-Glia Interaction

  2017cites this paper
• Mitochondrial function and dynamics in demyelinated axons

  2017cites this paper
• Mechanics of mitochondrial motility in neurons.

  2016cites this paper