H-2 mutations: their genetics and effect on immune functions.

No abstract is available for this paper.

• Publication year

  1978

• Venue

  Advances in Immunology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0065-2776(08)60229-1PMID 358801
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Major Histocompatibility System in Man and Animals

  2012cited by this paper
• Leucocyte Membrane Determinants Regulating Immune Reactivity.

  1978cited by this paper
• Genetic Control of the Immune Response to Thy‐1 Antigens 1

  1978cited by this paper
• Structural differences between the mouse H-2D products of the mutant B10.D2.M504 (H-2da) and the parental nonmutant strain B10.D2 (H-2d).

  1978cited by this paper
• Evidence for multiple clones of cytotoxic T cells responding to antigenic determinants on the same molecule.

  1978cited by this paper
• Localization of mouse Pgk-2 gene at the D end of the H-2 complex (1).

  1978cited by this paper
• Neonatal tolerance induction across regions of H-2 complex.

  1977cited by this paper
• Palatal cytosol cortisol-binding protein associated with cleft palate susceptibility and H–2 genotype

  1977cited by this paper
• Cytotoxic T-cell response to ectromelia virus-infected cells. Different H-2 requirements for triggering precursor T-cell induction or lysis by effector T cells defined by the BALB/c-H-2(db) mutation

  1977cited by this paper
• Gamma-ray-induced dominant mutations that cause skeletal abnormalities in mice. I. Plan, summary of results and discussion.

  1977cited by this paper
• Allograft reaction against H-2-region antigens.

  1977cited by this paper
• H-2 mutation affecting immune response to Thy-1.1 antigen

  1977cited by this paper
• Spontaneous mutation rates at enzyme loci in Drosophila melanogaster.

  1977cited by this paper
• Immunogenetic analysis of H-2 mutations. VII. Cells responding to H-2 Kk gene products give rise to an allogeneic supernatant.

  1977cited by this paper
• Histocompatibility-2 system in wild mice. V. Serologic analysis of sixteen B10.W congenic lines.

  1977cited by this paper
• MULTIPLE FOREIGN NON‐H‐2 DETERMINANTS ON THE SURFACE OF A CHEMICALLY‐INDUCED MURINE SARCOMA *

  1977cited by this paper
• Antigenic Requirements for Triggering of Cytotoxic T Lymphocytes

  1977cited by this paper
• The Use of H‐2 Mutants as Models for the Study of T Cell Activation

  1977cited by this paper
• Structural differences between parent and mutant H-2K glycoproteins from two H-2K gene mutants: b6.c-h-2ba (Hzl) and B6-H-2bd (M505).

  1977cited by this paper
• Immunogenetic analysis of H-2 mutations - VI. Crossreactivity in cell-mediated lympholysis between TNP-modified cells from H-2 mutant strains

  1977cited by this paper
• Relative importance of H-2 regions in the development of graft-versus-host reactions.

  1976cited by this paper
• Enzyme polymorphism in feral, outbred and inbred rats (Rattus norvegicus)

  1976cited by this paper
• PARTICIPATION OF H‐2 REGIONS IN HEART‐TRANSPLANT REJECTION

  1976cited by this paper
• Regulatory mechanisms in cell-mediated immune responses. III. I-region control of suppressor cell interaction with responder cells in mixed lymphocyte reactions

  1976cited by this paper
• Soluble factors substitute for T–T-cell collaboration in generation of T-killer lymphocytes

  1976cited by this paper
• H-2 compatibility requirement for virus-specific T-cell-mediated cytolysis. The H-2K structure involved is coded by a single cistron defined by H-2Kb mutant mice

  1976cited by this paper
• Divergent X-ray-induced mutation rates in the mouse for H and “7-locus” groups of loci

  1976cited by this paper
• H–2 region product as determinant in immune cytolysis of syngeneic tumour cells by anti-MSV T lymphocytes

  1976cited by this paper
• X-ray induced mutations, DNA and target theory

  1976cited by this paper
• Control of mating preferences in mice by genes in the major histocompatibility complex

  1976cited by this paper
• T-lymphocyte-enriched murine peritoneal exudate cells. II. Genetic control of antigen-induced T-lymphocyte proliferation

  1976cited by this paper
• Specific binding of alloantigens to T cells activated in the mixed lymphocyte reaction

  1976cited by this paper
• H–2-like specificities of foreign haplotypes appearing on a mouse sarcoma after vaccinia virus infection

  1976cited by this paper
• An attempted analysis of interstrain differences in the lymphoid system: strains B10, B10.A and A [proceedings].

  1976cited by this paper
• Influence of H-2 on the ontogenesis of a spleen cell population which lacks C3 receptors and Thy-1 antigen.

  1976cited by this paper
• Ability of H-2 regions to induce graft-vs-host disease.

  1976cited by this paper
• Role of major histocompatibility complex gene products in delayed-type hypersensitivity.

  1976cited by this paper
• Failure of X-rays to mutate class II histocompatibility loci in Balb/c mouse spermatogonia.

  1976cited by this paper
• IMMUNOGENETIC ANALYSIS OF H‐2 MUTATIONS: V. Serological Analysis of Mutations H‐2da, H‐2fa, and H‐2ka1

  1976cited by this paper
• An attempt at an interpretation of the mouse H-2 complex.

  1976cited by this paper
• The Genetics and Biology of Drosophila

  1976cited by this paper
• In vitro cell-mediated immune responses to the male specific(H-Y) antigen in mice

  1975cited by this paper
• H-2 compatability requirement for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus. Different cytotoxic T- cell specificities are associated with structures coded for in H-2K or H-2D;

  1975cited by this paper
• Histocompatibility gene mutation rates: H-2 and non-H-2

  1975cited by this paper
• Tumor-associated antigens in isoantigenic variants of a 3-methylcholanthrene-induced sarcoma.

  1975cited by this paper
• Are methylcholanthrene‐induced sarcoma‐associated, rejection‐inducing (TSTA) antigens, modified forms of H‐2 or linked determinants?

  1975cited by this paper
• The role of macrophages in the generation of T-helper cells. II. The genetic control of the macrophage-T-cell interaction for helper cell induction with soluble antigens

  1975cited by this paper
• On the role of the H-2 histocompatibility complex in determining the specificity of cytotoxic effector cells sensitized against syngeneic trinitrophenyl-modified targets

  1975cited by this paper
• The T-locus of the mouse

  1975cited by this paper
• Immunogeneic analysis of H-2 mutations. II. Cellular immunity to the H-2DA mutation.

  1975cited by this paper
• [Correlation between cytotoxic lymphocytes and cells that synthesize the macrophage migration inhibitory factor in the H-2 system].

  1975cited by this paper
• Immunogenetic Analysis of H‐2 Mutations

  1975cited by this paper
• The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens

  1975cited by this paper
• The mechanism of immunoresistance of H(z1) mice to C57BL/6 tumors.

  1975cited by this paper
• A new H-2 haplotype carrying possibly a mutation of H-2b.

  1975cited by this paper
• Tumour-associated transplantation antigens of chemically induced sarcomata cross reacting with allogeneic histocompatibility antigens

  1975cited by this paper
• Alien histocompatibility determinants on the cell surface of sarcomas induced by methylcholanthrene. I. In vivo studies

  1975cited by this paper
• Molecular relationship between private and public H-2 antigens as determined by antigen redistribution method

  1975cited by this paper
• A model for genetic analysis of programmed gene expression as reflected in the development of membrane antigens.

  1975cited by this paper
• Genetic control of immune responses in vitro. VI. Experimental conditions for the development of helper T-cell activity specific for the terpolymer L-glutamic aicd60-L-alanine30-L-tyrosine10 (GAT) in nonresponder mice

  1975cited by this paper
• Immunogenetic analysis of H-2 mutations. III. Genetic mapping and involvement in immune reactions of the H-2ka mutation.

  1975cited by this paper
• SEPARATE AND POLYMORPHIC LOCI CONTROLLING TWO TYPES OF POLYPEPTIDE CHAINS BEARING THE H‐2 PRIVATE AND PUBLIC SPECIFICITIES

  1975cited by this paper
• Association of mouse liver adenosine 3':5'-cyclic monophosphate (cyclic AMP) levels with histocompatibility-2 genotype.

  1975cited by this paper
• Influence of the H-2 system on the sensitivity of vesicular glands to testosterone hormone.

  1975cited by this paper
• Cell-mediated lympholysis of trinitrophenyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by H-2K and H-2D serological regions of the murine major histocompatibility complex

  1975cited by this paper
• DNA synthesis in lymph node cells of mice: differences associated with the H-2 system.

  1974cited by this paper
• Separation of the specific antigen of a mouse lymphoma from histocompatibility antigens.

  1974cited by this paper
• SEROLOGICAL DISTINCTION OF MUTANTS B6.C-H(z1) AND B6.M505 FROM STRAIN C57BL/6

  1974cited by this paper
• Haemagglutination and cytotoxic studies of H-2. V. T-e anti-27, 28, 29 family of antibodies.

  1974cited by this paper
• Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytes choriomeningitis

  1974cited by this paper
• Sex-dependent and H-2-linked influence on expressivity of the brachyury gene in mice.

  1974cited by this paper
• The effects of heterologous antisera to soluble proteins from horse leucocyte granules and rat liver mitochondrial-lysosomal fraction on the activity of some lysosomal hydrolases in vitro.

  1974cited by this paper
• ONTOGENY OF B LYMPHOCYTES

  1974cited by this paper
• Spontaneous histocompatibility mutations detected by dermal grafts: significant changes in rate over a 10-year period in the mouse H-system.

  1974cited by this paper
• Genetic (h-2) dependence of the duration of splenomegaly induced by Brucella abortus.

  1974cited by this paper
• Antibody-induced redistribution of normal and tumor associated surface antigens.

  1974cited by this paper
• Notable diversity in peptide composition of murine H-2K and H-2D alloantigens.

  1974cited by this paper
• PASSIVE ENHANCEMENT OF MOUSE SKIN ALLOGRAFTS: Specificity of the Antiserum for Major Histocompatibility Complex Antigens

  1974cited by this paper
• Immunological tolerance; mechanisms and potential therapeutic applications

  1974cited by this paper
• Mutation Induction in Mice

  1974cited by this paper
• THE GENETIC BASIS OF THE GENERATION OF EFFECTOR CAPACITY FOR CELL MEDIATED LYMPHOLYSIS IN MICE

  1974cited by this paper
• Restriction by H-2 gene complex of transfer of cell-mediated immunity to Listeria monocytogenes

  1974cited by this paper
• Removal of specific cooperative T cell factor by anti-H-2 but not by anti-Ig sera

  1974cited by this paper
• Demonstration by MLR test of a previously unsuspected intra-H-2 crossover in the B10.HTT strain: implications concerning location of MLR determinants in the Ir region.

  1973cited by this paper
• Lymphocyte reactivity to serologically undetected components of the major histocompatibility complex.

  1973cited by this paper
• A multivariate analysis of subline divergence in the shape of the mandible in C57BL-Gr mice.

  1973cited by this paper
• Genetic control of phytohemagglutinin responsiveness by murine spleen cells and correlation between the release of lymphotoxins and dna synthesis

  1973cited by this paper
• Controversy about MIRVs

  1973cited by this paper
• Cellular immunity in the mouse. 3. In vitro kinetic studies on the relationship between recognition and effector phases.

  1973cited by this paper
• Genetic differences in the manifestation of theta-C3H-antigen association with the H-2 system.

  1973cited by this paper
• MITOCHONDRIA IN ONCOGENESIS REVISITED

  1973cited by this paper
• Graft-vs-host reaction with an H-2 mutant.

  1973cited by this paper
• H-gene (histocompatibility) mutations induced by triethylenemelamine in the mouse.

  1973cited by this paper
• New lymphocyte antigen system (Lna) controlled by the Ir region of the mouse H-2 complex.

  1973cited by this paper
• New genetic model for allelism at histocompatibility and other complex loci: polymorphism for control of gene expression.

  1973cited by this paper
• Serological Identification of an Ir-Region Product

  1973cited by this paper
• The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.

  1973cited by this paper
• Replacement of T-cell function by a T-cell product.

  1972cited by this paper
• Histocompatibility mutations in mice: chemical induction and linkage with the H-2 locus.

  1972cited by this paper
• Mixed lymphocyte reaction caused by an H-2D mutation (congenic strains-B10.D2 new-B10.504).

  1972cited by this paper

• Studying Within-Host Viral Evolution Using Pooled Next-Generation Sequencing Data

  2016cites this paper
• The Wonder of Our Presence Here: A Commentary on the Evolution and Maintenance of Human Diversity

  2015cites this paper
• Determination of the Expression Patterns of Bovine Non-Classical Major Histocompatibility Complex (MHC) Class I Proteins

  2013cites this paper
• Advances in Human Genetics 10

  2012cites this paper
• SLA haplotype differences in lines of pigs which differ in ovulation rate.

  2009cites this paper
• Influence of genes associated with the main histocompatibility complex on deoxyribonucleic acid excision repair capacity and bleomycin sensitivity in mouse lymphocytes.

  2008cites this paper
• Biochemical individuality reflected in chromatographic, electrophoretic and mass-spectrometric profiles.

  2008cites this paper
• Chemical Identification of MHC-influenced Volatile Compounds in Mouse Urine. I: Quantitative Proportions of Major Chemosignals

  2007cites this paper
• MHC, TSP, and the origin of species: from immunogenetics to evolutionary genetics.

  2007cites this paper
• New evidence fortrans-species evolution of theH-2 class I polymorphism

  2006cites this paper
• Biochemical studies on the H-2K antigens of the MHC mutantsbm3 andbm11

  2005cites this paper
• MHC Class I and II Antigens as Targets of Rejection in Penetrating Keratoplasty in Low- and High-Risk Mouse Eyes

  2005cites this paper
• Studies ofH-2Kb mutant mice

  2005cites this paper
• Identification of two Ia-like alloantigens on rabbit B lymphocytes

  2005cites this paper
• Neonatal tolerance induction acrossH-2 mutational disparity: Induction and specificity of tolerance

  2005cites this paper
• H-2 antigen variants in a cultured heterozygous mouse leukemia cell line

  2005cites this paper
• Anti-H-2 antibodies induced by syngeneic immunization

  2005cites this paper
• Immune response to acute virus infection in the Syrian hamster

  2005cites this paper
• Biochemical studies on the H-2K antigens of the MHC mutantbm1

  2005cites this paper
• Monoclonal anti-H-2Kb antibodies detect serological differences betweenH-2Kb mutants

  2005cites this paper
• Liver tissue graft rejection in murine major histocompatibility complex mutants

  2004cites this paper
• The H-2dm1mutation and Qa antigens

  2004cites this paper
• Interactions between MHC-encoded products and cloned T-cells. I. Fine specificity of induction of proliferation and lysis

  2004cites this paper
• Synthesis of a defective H-2 histocompatibility antigen by mutant mouse strain BALB/c-H-2dm2

  2004cites this paper
• Biochemical studies of H-2K antigens from a group of related mutants. I. Identification of a shared mutation in B6-H-2bm5 and B6-H-2bm16

  2004cites this paper
• Immunoselection of structural H-2Kb variants: Use of cloned cytolytic T cells to select for loss of a CTL-defined allodeterminant

  2004cites this paper
• Clonal analysis of the specificity of alloreactive cells: “Dominance” of Eβ reactive clones

  2004cites this paper
• Cross-reactivity patterns of vaccinia-specific cytotoxic T lymphocytes from H-2Kbmutants

  2004cites this paper
• Syrian hamsters express two monomorphic class I major histocompatibility complex molecules

  2004cites this paper
• Alter the CD 8 T Cell Repertoire MHC Class I Gene Conversion Mutations Keulen

  2003cites this paper
• Assays of Cell-mediated Cytotoxicity

  2003cites this paper
• Generation of Helper Factor Supernatants

  2003cites this paper
• MHC Class I Gene Conversion Mutations Alter the CD8 T Cell Repertoire

  2003cites this paper
• Primary In Vitro Stimulation ofMonoclonal CTL

  2003cites this paper
• Discrimination of MHC-derived odors by untrained mice is consistent with divergence in peptide-binding region residues

  2002cites this paper
• Accumulated background variation among H2 mutant congenic strains: elimination through PCR-based genotyping of F2 segregants.

  2001cites this paper
• Molecular Evolution of the Mouse Major Histocompatibility Complex -The Detection of Low Frequency Gene Conversion Events

  2001influential citation
• The gene conversion hypothesis of MHC evolution: a review

  1999influential citation
• The enigma of skin allograft rejection

  1998cites this paper
• Recombination in the mammalian germ line.

  1998cites this paper
• Histocompatibility gene mutation rates in the mouse: a 25-year review

  1997cites this paper
• Alloimmunization Against Well Defined Polymorphic Major Histocompatibility or Class I MHC Transfected L Cells Antigens Can Prevent Poly IC Induced Fetal Death in Mice

  1995cites this paper
• Alone on the heart of the earth: an immunogeneticist's journey into the past.

  1994cites this paper
• Origins of Mhc Diversity

  1993cites this paper
• Evolution of the mouse H-2K region: a hot spot of mutation associated with genes transcribed in embryos and/or germ cells.

  1992cites this paper
• Evolutionary consequences of nonrandom damage and repair of chromatin domains

  1992cites this paper
• Immunologic responses in central nervous system transplantation

  1992cites this paper
• Autoimmune thyroiditis (EAT) in genetically resistant mice mediated by a T cell line.

  1992cites this paper
• Selection for class IIMhc heterozygosity by parasites in subterranean mole rats

  1992cites this paper
• Immunology. Disease and evolution.

  1991cites this paper
• Disease and evolution

  1991cites this paper
• Maintenance of Multiallelic Polymorphism at the MHC Region

  1991cites this paper
• Evolution of class II genes: Role of selection in both the maintenance of polymorphism and the retention of non-expressed alleles

  1990cites this paper
• Spontaneous frequency of H-2 mutations.

  1990cites this paper
• DNA recombination and natural selection pressure sustain genetic sequence diversity of the feline MHC class I genes

  1990cites this paper
• Immune mechanisms in autoimmune thyroiditis.

  1989cites this paper
• The Reproductive Consequences of Carriers of Methylenebisacrylamide-Induced Balanced Reciprocal Translocations in Mus Musculus

  1989cites this paper
• Alien antigens return to the fold.

  1989cites this paper
• Realm of Tolerance

  1989cites this paper
• Detection of new MHC mutations in mice by skin grafting, tumor transplantation and monoclonal antibodies: a comparison.

  1988cites this paper
• Genetic and Environmental Regulation of the Cytolytic T Lymphocyte Receptor Repertoire Specific for Alloantigen

  1988cites this paper
• Regulation of the Immune and Nonimmune Aging Process by the Major Histocompatibility Complex

  1988cites this paper
• Microrecombinations generate sequence diversity in the murine major histocompatibility complex: analysis of the Kbm3, Kbm4, Kbm10, and Kbm11 mutants

  1988cites this paper
• H-2 polymorphisms are more uniformly distributed than allozyme polymorphisms in natural populations of house mice.

  1988cites this paper
• Nature of polymorphism in HLA-A, -B, and -C molecules.

  1988cites this paper
• Major histocompatibility complex polymorphism: a nonimmune theory for selection.

  1988cites this paper
• The H-2Kkml mutation: a single nucleotide substitution is responsible for multiple functional differences in a class I MHC molecule.

  1988cites this paper
• Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection

  1988cites this paper
• Immune response to H-2 class I antigens on platelets. II. Specific decrease of H-2 class I-specific antibody response induced by treatment with allogeneic platelets.

  1988cites this paper
• Analysis of structure/function relationships among major histocompatibility complex class I antigens

  1987cites this paper
• Determinants on major histocompatibility complex class I molecules recognized by cytotoxic T lymphocytes.

  1987cites this paper
• Function and specificity of T cell subsets in the mouse.

  1987cites this paper
• Chapter 8 The immunoglobulin superfamily

  1987cites this paper
• Can Heterozygote Advantage Account for the Maintenance of H-2 Polymorphisms

  1987cites this paper
• Somatic cell variants of the murine major histocompatibility complex

  1987cites this paper
• The H-ZKkm1 mutation: Nucleotide sequence and comparative analysis

  1987cites this paper
• Involvement of the H-2 Complex in Steroid Hormone Metabolism

  1987cites this paper
• Immunogenic (tum−) variants obtained by mutagenesis of mouse mastocytoma P815

  1987cites this paper
• The H-2Kkml mutation: nucleotide sequence and comparative analysis.

  1987cites this paper
• Is allograft rejection a clue to the mechanism promoting MHC polymorphism?

  1987cites this paper
• Recombination and the concerted evolution of the murine MHC

  1987cites this paper
• Biochemical and functional analyses of a secreted H-2Ld molecule

  1986cites this paper
• Mitotic recombination in germ cells generated two major histocompatibility complex mutant genes shown to be identical by RNA sequence analysis: Kbm9 and Kbm6.

  1986cites this paper
• Properties of purified T cell subsets. II. In vivo responses to class I vs. class II H-2 differences

  1986influential citation
• Effect of swine lymphocyte antigen haplotypes on birth and weaning weights in pigs.

  1986cites this paper
• Functions of Purified L3T4+ and Lyt‐2+ Cells in vitro and in vivo

  1986cites this paper
• A mouse tumor-specific transplantation antigen is a heat shock-related protein.

  1986cites this paper
• Interaction between Kb and Q4 gene sequences generates the Kbm6 mutation

  1986influential citation
• Characterization of a chemically homogeneous tumor antigen from a methylcholanthrene-induced sarcoma, Meth A.

  1986cites this paper
• Diversification of H-2 Genes through Recombination: A Study of Kb Mutants

  1986cites this paper
• Properties of purified T cell subsets. I. In vitro responses to class I vs. class II H-2 alloantigens

  1985cites this paper
• Maternal recognition of pregnancy in the ewe, cow and sow: Vascular and immunological aspects

  1985cites this paper
• Sheep lymphocyte antigens (OLA). II. Major histocompatibility complex class II molecules.

  1985cites this paper
• Molecular basis of the dm1 mutation in the major histocompatibility complex of the mouse: a D/L hybrid gene

  1985cites this paper
• An analysis of monoclonal T cell and antibody recognition sites on Ia molecules.

  1985cites this paper
• Endocytosis of MHC Molecules Evaluated by Specifically Targeted Liposomes

  1985cites this paper
• Molecular characterization of novel H-2 class I molecules expressed by a C3H UV-induced fibrosarcoma.

  1985cites this paper
• Graft-vs.-host reactions: mechanisms and contemporary theories.

  1985cites this paper
• Immunological surveillance of tumors in the context of major histocompatibility complex restriction of T cell function.

  1984cites this paper
• HLA loss variants of a B27+ lymphoblastoid cell line: genetic and cellular characterization.

  1984cites this paper