DNA double-strand break repair pathways and cellular tolerance to inhibitors of topoisomerase II.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Cancer Research

• Publication date

  1990-09-15

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 2168280
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Relationship between topoisomerase II and radiosensitivity in mouse L5178Y lymphoma strains.

  1989cited by this paper
• Cytogenetical characterization of Chinese hamster ovary X-ray-sensitive mutant cells, xrs 5 and xrs 6. IV. Study of chromosomal aberrations and sister-chromatid exchanges by restriction endonucleases and inhibitors of DNA topoisomerase II.

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• DNA topoisomerase poisons as antitumor drugs.

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• Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note.

  1989cited by this paper
• A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication.

  1988cited by this paper
• Topoisomerase inhibitors induce irreversible fragmentation of replicated DNA in concanavalin A stimulated splenocytes.

  1988cited by this paper
• Cell cycle dependence of sister chromatid exchange induction by DNA topoisomerase II inhibitors in Chinese hamster V79 cells.

  1987cited by this paper
• Cross-sensitivity to topoisomerase II inhibitors in cytotoxic drug-hypersensitive Chinese hamster ovary cell lines.

  1987cited by this paper
• Recent studies of DNA topoisomerases.

  1987influential reference
• Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro.

  1987cited by this paper
• Characterization of acquired epipodophyllotoxin resistance in a Chinese hamster ovary cell line: loss of drug-stimulated DNA cleavage activity.

  1986cited by this paper
• Cross-resistance to intercalating agents in an epipodophyllotoxin-resistant Chinese hamster ovary cell line: evidence for a common intracellular target.

  1986cited by this paper
• Reduced formation of protein-associated DNA strand breaks in Chinese hamster cells resistant to topoisomerase II inhibitors.

  1986cited by this paper
• Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide.

  1985cited by this paper
• Effects of DNA intercalating agents on topoisomerase II induced DNA strand cleavage in isolated mammalian cell nuclei.

  1985cited by this paper
• In vivo mapping of DNA topoisomerase II-specific cleavage sites on SV40 chromatin.

  1985cited by this paper
• DNA topoisomerases.

  1985cited by this paper
• Inhibition of etoposide-induced DNA damage and cytotoxicity in L1210 cells by dehydrogenase inhibitors and other agents.

  1984cited by this paper
• DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication.

  1984cited by this paper
• Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

  1984cited by this paper
• X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining.

  1984cited by this paper
• Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

  1984cited by this paper
• Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage.

  1984cited by this paper
• DNA damage as a basis for 4'-demethylepipodophyllotoxin-9-(4,6-O-ethylidene-beta-D-glucopyranoside) (etoposide) cytotoxicity.

  1983cited by this paper
• Free radical metabolism of VP-16 and inhibition of anthracycline-induced lipid peroxidation.

  1983cited by this paper
• Cleavage of DNA by mammalian DNA topoisomerase II.

  1983cited by this paper
• X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents.

  1983cited by this paper
• A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange.

  1982cited by this paper
• Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino) methanesulfon-m-anisidide and adriamycin.

  1981cited by this paper
• DNA gyrase and the supercoiling of DNA.

  1980cited by this paper
• X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution.

  1979cited by this paper
• Protein-associated DNA breaks in cells treated with adriamycin or ellipticine.

  1978cited by this paper

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