Skin Wound Healing: An Update on the Current Knowledge and Concepts

No abstract is available for this paper.

• Publication year

  2016

• Venue

  European Surgical Research

• Publication date

  2016-12-15

• Fields of study

  Medicine

• Identifiers
  DOI 10.1159/000454919PMID 27974711
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A cold plasma jet accelerates wound healing in a murine model of full‐thickness skin wounds

  2017cited by this paper
• Angiogenesis and wound repair: when enough is enough

  2016cited by this paper
• Induction of proliferation of basal epidermal keratinocytes by cold atmospheric‐pressure plasma

  2016cited by this paper
• Human umbilical mesenchymal stem cells conditioned medium promote primary wound healing regeneration

  2016cited by this paper
• Grand challenge in Biomaterials-wound healing

  2016cited by this paper
• Transition from inflammation to proliferation: a critical step during wound healing

  2016cited by this paper
• Accelerated wound healing in a diabetic rat model using decellularized dermal matrix and human umbilical cord perivascular cells.

  2016cited by this paper
• Cellular mechanisms of skin repair in humans and other mammals

  2016cited by this paper
• Targeting the myofibroblast to improve wound healing

  2016cited by this paper
• Cellular and molecular mechanisms involved in scarless wound healing in the fetal skin

  2016cited by this paper
• Epithelial-mesenchymal transition in tissue repair and fibrosis

  2016cited by this paper
• Engineered Biopolymeric Scaffolds for Chronic Wound Healing

  2016cited by this paper
• Current Concepts in Tissue Engineering: Skin and Wound

  2016cited by this paper
• Reduced cell cohesiveness of outgrowths from eccrine sweat glands delays wound closure in elderly skin

  2016cited by this paper
• Cutting Edge: Regulatory T Cells Facilitate Cutaneous Wound Healing

  2016cited by this paper
• Pericytes: A newly recognized player in wound healing

  2016cited by this paper
• Methodologies in creating skin substitutes

  2016cited by this paper
• Macrophage PPARγ and impaired wound healing in type 2 diabetes

  2015cited by this paper
• Atmospheric pressure nonthermal plasmas for bacterial biofilm prevention and eradication.

  2015cited by this paper
• Insight into Reepithelialization: How Do Mesenchymal Stem Cells Perform?

  2015cited by this paper
• Chemokine Regulation of Angiogenesis During Wound Healing

  2015cited by this paper
• Pigment epithelium-derived factor as a multifunctional regulator of wound healing.

  2015cited by this paper
• Stem cell heterogeneity and plasticity in epithelia.

  2015cited by this paper
• How leukocytes cross the vascular endothelium

  2015cited by this paper
• Skin and wound decontamination of multidrug‐resistant bacteria by cold atmospheric plasma coagulation

  2015cited by this paper
• Dual effects of atmospheric pressure plasma jet on skin wound healing of mice

  2015cited by this paper
• Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications

  2015cited by this paper
• Epithelialization in Wound Healing: A Comprehensive Review

  2014cited by this paper
• Wound repair and regeneration: Mechanisms, signaling, and translation

  2014cited by this paper
• Regenerative healing, scar‐free healing and scar formation across the species: current concepts and future perspectives

  2014cited by this paper
• Non-Thermal Atmospheric Pressure Plasma Preferentially Induces Apoptosis in p53-Mutated Cancer Cells by Activating ROS Stress-Response Pathways

  2014cited by this paper
• Updated scar management practical guidelines: non-invasive and invasive measures.

  2014cited by this paper
• Innate and Adaptive Immune Responses in Wound Epithelialization

  2014cited by this paper
• Plasticity of epithelial stem cells in tissue regeneration

  2014cited by this paper
• Nonthermal Atmospheric Pressure Plasma Enhances Mouse Limb Bud Survival, Growth, and Elongation

  2014cited by this paper
• Altered TGF‐β signaling in fetal fibroblasts: What is known about the underlying mechanisms?

  2014cited by this paper
• Deregulation of epidermal stem cell niche contributes to pathogenesis of nonhealing venous ulcers

  2014cited by this paper
• Placenta mesenchymal stem cell accelerates wound healing by enhancing angiogenesis in diabetic Goto-Kakizaki (GK) rats.

  2013cited by this paper
• Complements and the Wound Healing Cascade: An Updated Review

  2013cited by this paper
• Eccrine sweat glands are major contributors to reepithelialization of human wounds.

  2013cited by this paper
• Neutrophil Transmigration: Emergence of an Adhesive Cascade within Venular Walls

  2013cited by this paper
• Comparative wound healing—Are the small animal veterinarian's clinical patients an improved translational model for human wound healing research?

  2013cited by this paper
• Disclosure of the Culprits: Macrophages—Versatile Regulators of Wound Healing

  2013cited by this paper
• Antimicrobial Efficacy of Two Surface Barrier Discharges with Air Plasma against In Vitro Biofilms

  2013cited by this paper
• Transendothelial Migration Enables Subsequent Transmigration of Neutrophils through Underlying Pericytes

  2013cited by this paper
• Microvascular remodeling and wound healing: a role for pericytes.

  2012cited by this paper
• Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo

  2012cited by this paper
• Altered angiogenic balance in keloids: a key to therapeutic intervention.

  2012cited by this paper
• HMG-CoA Reductase Inhibitors (Statins) Reduce Hypertrophic Scar Formation in a Rabbit Ear Wounding Model

  2012cited by this paper
• Wound Healing Angiogenesis: Innovations and Challenges in Acute and Chronic Wound Healing

  2012cited by this paper
• Participation of blood vessel cells in human adaptive immune responses.

  2012cited by this paper
• Bone Marrow–derived Mesenchymal Stem Cells Transplantation Accelerates Tissue Expansion by Promoting Skin Regeneration During Expansion

  2011cited by this paper
• Wound macrophages as key regulators of repair: origin, phenotype, and function.

  2011cited by this paper
• ‘White wave’ analysis of epithelial scratch wound healing reveals how cells mobilise back from the leading edge in a myosin-II-dependent fashion

  2011cited by this paper
• Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

  2011cited by this paper
• An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice.

  2011cited by this paper
• Topical embryonic stem cells enhance wound healing in diabetic rats

  2011cited by this paper
• Differential Roles of Macrophages in Diverse Phases of Skin Repair

  2010cited by this paper
• Tissue scaffolds for skin wound healing and dermal reconstruction.

  2010cited by this paper
• Pattern recognition receptors and inflammation.

  2010cited by this paper
• Macrophage Dysfunction Impairs Resolution of Inflammation in the Wounds of Diabetic Mice

  2010cited by this paper
• Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis.

  2010cited by this paper
• Die rekonstruktive Sequenz des 21. Jahrhunderts

  2010cited by this paper
• [The reconstructive sequence in the 21st century. A reconstructive clockwork].

  2010cited by this paper
• Matrix metalloproteinase inhibition delays wound healing and blocks the latent transforming growth factor‐β1‐promoted myofibroblast formation and function

  2010cited by this paper
• Disparate Companions: Tissue Engineering Meets Cancer Research

  2010cited by this paper
• Cell contraction forces in scaffolds with varying pore size and cell density.

  2010cited by this paper
• Bevacizumab: a potential agent for prevention and treatment of hypertrophic scar.

  2010cited by this paper
• Human CD133+ Progenitor Cells Promote the Healing of Diabetic Ischemic Ulcers by Paracrine Stimulation of Angiogenesis and Activation of Wnt Signaling

  2009cited by this paper
• Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery

  2009cited by this paper
• Lipomatosis-associated inflammation and excess collagen may contribute to lower relative resting energy expenditure in women with adiposis dolorosa

  2009cited by this paper
• Fetal skin wound healing.

  2009cited by this paper
• Chapter 6 Fetal Skin Wound Healing

  2009cited by this paper
• Exploring the full spectrum of macrophage activation

  2008cited by this paper
• New therapeutics for the prevention and reduction of scarring.

  2008cited by this paper
• Skin Tissue Engineering for Tissue Repair and Regeneration

  2008cited by this paper
• Cellular and molecular pathology of HTS: basis for treatment

  2007cited by this paper
• Regulation of angiogenesis: wound healing as a model.

  2007cited by this paper
• Intravital insights in skin wound healing using the mouse dorsal skin fold chamber

  2007cited by this paper
• Collective cell migration patterns: Follow the leader

  2007cited by this paper
• Silicone gel sheeting for preventing and treating hypertrophic and keloid scars.

  2006cited by this paper
• Low-dose enalapril in the treatment of surgical cutaneous hypertrophic scar and keloid--two case reports and literature review.

  2006cited by this paper
• Distinct Patterns of Angiogenesis in Oral and Skin Wounds

  2005cited by this paper
• Cellular and molecular facets of keratinocyte reepithelization during wound healing.

  2005cited by this paper
• The assessment of erythema and thickness on burn related scars during pressure garment therapy as a preventive measure for hypertrophic scarring.

  2005cited by this paper
• Multiple rows of cells behind an epithelial wound edge extend cryptic lamellipodia to collectively drive cell-sheet movement

  2005cited by this paper
• Regulation of wound healing by growth factors and cytokines.

  2003cited by this paper
• Secretory granule exocytosis.

  2003cited by this paper
• Rho-dependent formation of epithelial “leader” cells during wound healing

  2003cited by this paper
• Wound healing in the PU.1 null mouse--tissue repair is not dependent on inflammatory cells.

  2003cited by this paper
• Myofibroblasts and mechano-regulation of connective tissue remodelling

  2002cited by this paper
• [International clinical recommendations on scar management].

  2002cited by this paper
• International clinical recommendations on scar management.

  2002cited by this paper
• Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation.

  2001cited by this paper
• Mechanisms of epithelial fusion and repair

  2001cited by this paper
• Differential production of apoptosis-modulating proteins in patients with hypertrophic burn scar.

  1998cited by this paper
• Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

  1998cited by this paper
• Fetal Wound Healing: The Ontogeny of Scar Formation in the Nonhuman Primate

  1995cited by this paper
• Transendothelial migration.

  1993cited by this paper
• Fetal Wound Healing The Ontogeny of Scar Formation in the Non‐Human Primate

  1993cited by this paper

• Objective assessment of cesarean section suturing techniques using a uterine simulator

  2026cites this paper
• Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerative Healing

  2026cites this paper
• Design of tadalafil loaded-gelatin/zein films: functional and biopharmaceutical characterization, photoprotection, and pro-angiogenic activities in yolk sac membrane assay

  2026cites this paper
• Electronic Bandage With High‐Resolution Interdigital Electrode Enhanced Pulsed Electric Field for Accelerated Wound Healing

  2026cites this paper
• [Reconstruction of large soft tissue defects].

  2026cites this paper
• Rhomboid protease Rhbdl2 regulates macrophage recruitment and wound regeneration in zebrafish

  2026cites this paper
• Honey Hydrogel Patch Assisted by Ultraviolet Exposure: Characterization and Adhesion Analyses

  2026cites this paper
• A mechanically tunable photo-cured hydrogel system based on methacrylated collagen-keratin inter-penetrating networks for rapid and enhanced wound healing.

  2026cites this paper
• Using electrochemical environmental sensing to detect chitosan hydrogel to repair sports training skin wounds: Sports injury prevention

  2026cites this paper
• Advancements in chitosan-based hydrogel synthesis using ionizing radiation for medical purposes: opportunities and challenges.

  2026cites this paper
• Commiphora myrrha-functionalized bacterial cellulose as a potential wound healing biomaterial

  2026cites this paper
• Topical Formulations Containing Mentha piperita for Wound Healing: A Scoping Review

  2026cites this paper
• Clinical and Histopathological Outcomes of High-Purity Type I Collagen in Chronic Wounds: A Systematic Review of Four Randomized Controlled Trials

  2026cites this paper
• Application of Adipose-Derived Mesenchymal Stem Cell 3D Spheroid, Microblock, as a Skin Regeneration Therapy.

  2026cites this paper
• Evaluation of ozonated oil and centella asiatica extract on excisional wound healing in Mice

  2026cites this paper
• From basic biology to engineered therapies: the keratinocyte stem cell playbook.

  2026cites this paper
• Electrospun Chitosan–Poly(vinyl alcohol) Nanofibers Functionalized with Natural Bioactive Compounds: Design, Physicochemical Characterization and Release Profiles

  2026cites this paper
• Ciprofloxacin-loaded chitosan microparticles for controlled drug delivery: A novel gelatin-based wound dressing

  2026cites this paper
• Current perspectives of bacteriophage therapy for multidrug-resistant wound infections

  2026cites this paper
• Hypericin as a Photodynamic Immunomodulator: A Natural Compound for Dermatological Therapy

  2026cites this paper
• Efficacy of antioxidant nanoparticulated systems in the treatment of burn injuries in vivo: A systematic review

  2026cites this paper
• Potential Application of Plant-Derived Extracellular Vesicles in Treatment of Burn Wounds

  2026influential citation
• Mesenchymal Stem Cells-Derived Exosomes: Next-Generation Nanomedicines Toward Scarless Wound Healing.

  2026cites this paper
• Hair follicle-inspired therapies for wound healing and scar remodelling.

  2025cites this paper
• Clinical Application of Artificial Dermis Combined with Autologous Split-thickness Skin Grafting for Traumatic Soft Tissue Defect

  2025cites this paper
• Antibacterial and Regenerative Potential of Zinc Oxide Nanoparticles and Carboxymethyl Cellulose for Infected Wound Healing in Rats.

  2025cites this paper
• Trichostatin A ameliorated combined radiation and skin wound injury-induced mortality and hematopoietic suppression in a rat model

  2025cites this paper
• D-Tryptophan Promotes Skin Wound Healing via Extracellular Matrix Remodeling in Normal and Diabetic Models

  2025influential citation
• Negative pressure mechanical signal increases the phosphorylation of eNOS Ser1177 by upregulating HSP90 expression to promote wound angiogenesis.

  2025cites this paper
• Ring-segment piezopolymer sensor optimized for cylindrical-wave detection in optical-resolution optoacoustic angiography with extended imaging depth

  2025cites this paper
• Supercritical Carbon Dioxide-Processed Acellular Dermal Matrix Patch for Enhanced Wound Healing

  2025cites this paper
• Organ synergy in poly(vinylidene fluoride)-based piezoelectrical materials for tissue engineering

  2025cites this paper
• Stimulant immobilized bioactive film of functionalized egg albumin blend for wound healing.

  2025cites this paper
• Three-Dimensional Bioprinting of Biphasic Nanobioink for Enhanced Diabetic Wound Healing.

  2025cites this paper
• Harnessing the power of stem cell-derived exosomes: a rejuvenating therapeutic for skin and regenerative medicine

  2025cites this paper
• Determinants of residual myometrial thickness after cesarean delivery: Comparative analysis of barbed versus conventional sutures—A sub‐analysis from the SPIRAL trial

  2025cites this paper
• Topical Vitamin E (Alpha-tocopherol) from Red Palm Oil (Elaeis guineensis) Improved Full-thickness Wound Healing in Male Wistar Rats (Rattus norvegicus)

  2025cites this paper
• Fabrication and characterization of metoprolol succinate loaded chitosan- guar gum based bio scaffolds for infected wound healing and tissue regeneration: In vitro and in vivo assessment.

  2025cites this paper
• The Causal Effect of Iron Traits on Risk of Hypertrophic Scarring: A Two‐Sample Mendelian Randomization Study

  2025cites this paper
• Glove-like hand: A case of severe-circumferential hand degloving injury

  2025cites this paper
• Efficacy of red betel (Piper ornatum) in accelerating perineal wound healing in postpartum women

  2025cites this paper
• F-actin Dynamics Regulates Collective Cell Migration by Modulating Cell Shape and Stress Correlation.

  2025cites this paper
• Comparative Analysis of Preoperative and Postoperative Voice Parameters in 93 Cases of Vocal Fold Cyst.

  2025cites this paper
• Medical gas plasma modifies Nrf2 signaling in diabetic wound healing

  2025cites this paper
• Programmed wound healing in aged skin may be enhanced by mesenchymal cell loaded gene-activated scaffolds

  2025cites this paper
• Recent advancements in magnetic starch-based composites for biomedical applications: A review.

  2025cites this paper
• MXenes in the application of diabetic foot: mechanisms, therapeutic implications and future perspectives

  2025cites this paper
• Synergistic Wound Healing Effects of Hibiscus rosa-sinensis and Centella asiatica Extracts Combination (HRSCA): in vivo and 3D Organotypic Models

  2025cites this paper
• Inhibition of CDK5 signaling mediated inflammation in macrophages promotes cutaneous wound healing

  2025cites this paper
• Skin Regeneration and Wound Healing by Plant Protein‐Based Electrospun Fiber Scaffolds and Patches for Tissue Engineering Applications

  2025cites this paper
• Peptide RL‐QN15 Regulates Functions of Epidermal Stem Cells to Accelerate Skin Wound Regeneration via the FZD8/β‐Catenin Axis

  2025cites this paper
• Natural Products for Improving Soft Tissue Healing: Mechanisms, Innovations, and Clinical Potential

  2025cites this paper
• Marine Jellyfish Collagen and Other Bioactive Natural Compounds from the Sea, with Significant Potential for Wound Healing and Repair Materials

  2025cites this paper
• Evaluating scar outcomes in pediatric burn patients following skin grafting

  2025cites this paper
• Current Strategies to Produce 3D Electrospun-Based Wound Dressings for Skin Regeneration

  2025cites this paper
• GelMA/AgNWs Hydrogel Combined with Electrical Stimulation Effectively Promotes Skin Wound Healing

  2025cites this paper
• Microgravity modulates keratinocyte, fibroblast, and endothelial cell communication during wound healing.

  2025cites this paper
• Veratric acid and zinc: a synergistic approach to accelerated wound healing in rats

  2025cites this paper
• Clinical application of chitosan-based biopolymer wound dressing in the treatment of a patient with lymphoma and extensive chronic wounds

  2025cites this paper
• Hypertrophic and Keloid Scar Management: Advances in Diagnosis, Perioperative Care, and Anesthetic Modulation

  2025cites this paper
• Influence of N‐Succinyl Chitosan Substitution on Hydrogel Properties for Wound Dressings

  2025cites this paper
• Randomized controlled trial comparing single-use negative-pressure wound therapy (sNPWT) with standard dressings during tissue expander-to-implant exchanges. Assessment of risk factors for impaired wound healing and clinical indications for sNPWT.

  2025cites this paper
• Soft Materials and Devices Enabling Sensorimotor Functions in Soft Robots.

  2025cites this paper
• Red-light LED therapy promotes wound regeneration by upregulating COL1A1, COL2A1, VEGF and reducing IL-1β for anti-inflammation

  2025cites this paper
• Perioperative Drug Management of Systemic Therapies in Breast Cancer: A Literature Review and Treatment Recommendations

  2025cites this paper
• Layer-By-Layer Functionalized Gauze With Designed α-Sheet Peptides Inhibits E. coli and S. aureus Biofilm Formation.

  2025cites this paper
• Laminaria japonica polysaccharide nano‑silver film with synergistic antibiosis for wound healing.

  2025cites this paper
• Cationic porphyrin-based covalent organic frameworks for enhanced phototherapy and targeted chemotherapy of bacterial infections.

  2025cites this paper
• Wound Treatment with a Dressing Spray Based on St John’s Wort Oil and Neem Oil: A Narrative Review

  2025cites this paper
• The Effect of Agave Bagasse Extract on Wound Healing in a Murine Model

  2025cites this paper
• MSC-EVs and UCB-EVs promote skin wound healing and spatial transcriptome analysis

  2025cites this paper
• Plant-Derived B-CGT Hydrogel Accelerates Diabetic Wound Healing Through Multitarget Modulation of Inflammation, Angiogenesis, and Tissue Remodeling

  2025cites this paper
• In vitro biocompatibility and drug release of collagen-mo-complexes hydrogels for tissue engineering

  2025cites this paper
• In Vivo Anti-Inflammatory and Wound Healing Activity of Extracts and Micro-Aerogels of Bursera microphylla A. Gray

  2025cites this paper
• Emerging roles of hyaluronic acid hydrogels in cancer treatment and wound healing: A review.

  2025cites this paper
• New Perspectives of Hydrogels in Chronic Wound Management

  2025cites this paper
• Biodegradable temporizing matrix utilization on a pediatric burn following an exploratory laparotomy

  2025cites this paper
• Therapeutic potential of phloridzin carbomer gel for skin inflammatory healing in atopic dermatitis

  2025cites this paper
• Critical Understanding of Apoptosis’ Function in Diabetes and Diabetic Wound Healing: Prospective Therapeutic Opportunities

  2025cites this paper
• New information on the etiology and biological targets of wounds associated with diabetes

  2025cites this paper
• MXenes as emerging materials to repair electroactive tissues and organs

  2025cites this paper
• Reducing oxidative stress and enhancing antioxidant defenses for faster healing in diabetic wounds: The role of topical metformin

  2025cites this paper
• Nickel Selenide‐Loaded PANI/PEO Fibers for Boosted Wound Healing Response in Rabbits

  2025cites this paper
• Skin and Wound Healing: Conventional Dosage versus Nanobased Emulsions Forms

  2025cites this paper
• A photothermal antimicrobial, antioxidant hydrogel for healing of bacterial-infected wounds

  2025cites this paper
• Microenvironment of diabetic foot ulcers: Implications for healing and therapeutic strategies

  2025cites this paper
• Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing

  2025cites this paper
• Biomaterial-based chitosan nanohydrogel films: combination of Bistorta officinalis and Ca-doped carbon dots for improved blood clotting

  2025cites this paper
• PROBLEMS OF HEALING SOFT TISSUE INJURIES

  2025cites this paper
• PERSONALIZATION OF TREATMENT TACTICS FOR PATIENTS WITH CHRONIC WOUNDS BASED ON GENETIC RESEARCH

  2025cites this paper
• Exploring the Association between Inflammatory Factors and the Development of Pathological Scars

  2025cites this paper
• Well-regulated Dermal Regeneration Using Amnion-containing Scaffold in a Preclinical Study

  2025cites this paper
• Reactive Oxygen Species and Antioxidants in Wound Healing: Mechanisms and Therapeutic Potential

  2025cites this paper
• Calycosin-7-glucoside-Loaded Hydrogel Promotes Wound Healing in Gestational Diabetes Mellitus.

  2025cites this paper
• FOSL1 promotes keratinocyte migration and wound repair by modulating the IL17 signaling pathway

  2025cites this paper
• Topical metformin in wound healing: a comprehensive systematic review of therapeutic outcomes

  2025cites this paper
• The use of platelet-rich plasma for skin wound repair in clinical trials: a systematic review

  2025cites this paper
• From current landscape to future horizon in stem cell therapy for tissue regeneration and wound healing: bridging the gap

  2025cites this paper
• Comparative Histological Changes to Investigate the Therapeutic Effect of Cicalfate+ cream and Penicillin-Streptomycin on Wound Healing in Rabbits

  2025cites this paper
• Evaluation of anti-inflammatory and wound healing properties of Tinospora cordifolia extract

  2025cites this paper