Identification of the functional domains of yeast sorting nexins Vps5p and Vps17p.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Molecular Biology of the Cell

• Publication date

  2002-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/MBC.02-05-0064PMID 12181349PMCID PMC117945
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Vps26p, a component of retromer, directs the interactions of Vps35p in endosome-to-Golgi retrieval.

  2001influential reference
• All Phox Homology (PX) Domains from Saccharomyces cerevisiae Specifically Recognize Phosphatidylinositol 3-Phosphate*

  2001influential reference
• Hrs Interacts with Sorting Nexin 1 and Regulates Degradation of Epidermal Growth Factor Receptor*

  2001influential reference
• Sorting Nexin 6, a Novel SNX, Interacts with the Transforming Growth Factor-β Family of Receptor Serine-Threonine Kinases*

  2001cited by this paper
• Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes

  2001influential reference
• A large family of endosome-localized proteins related to sorting nexin 1.

  2001cited by this paper
• SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P

  2001influential reference
• Self-assembly and binding of a sorting nexin to sorting endosomes.

  2001influential reference
• Phox homology domains specifically bind phosphatidylinositol phosphates.

  2001influential reference
• Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes.

  2000influential reference
• Direct Involvement of Phosphatidylinositol 4-Phosphate in Secretion in the Yeast Saccharomyces cerevisiae *

  1999cited by this paper
• SNX5, a new member of the sorting nexin family, binds to the Fanconi anemia complementation group A protein.

  1999cited by this paper
• Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities

  1998cited by this paper
• A Membrane Coat Complex Essential for Endosome-to-Golgi Retrograde Transport in Yeast

  1998influential reference
• Identification of a Family of Sorting Nexin Molecules and Characterization of Their Association with Receptors

  1998influential reference
• Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains.

  1998cited by this paper
• Linking cargo to vesicle formation: receptor tail interactions with coat proteins.

  1997cited by this paper
• The yeast VPS5/GRD2 gene encodes a sorting nexin-1-like protein required for localizing membrane proteins to the late Golgi.

  1997cited by this paper
• A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptor.

  1997influential reference
• Endosome to Golgi Retrieval of the Vacuolar Protein Sorting Receptor, Vps10p, Requires the Function of the VPS29, VPS30, and VPS35 Gene Products

  1997influential reference
• Coats and vesicle budding.

  1997cited by this paper
• Coat Proteins and Vesicle Budding

  1996cited by this paper
• Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3‐kinases: Binding partners of SH3 domains?

  1996cited by this paper
• Enhanced Degradation of EGF Receptors by a Sorting Nexin, SNX1

  1996influential reference
• VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae

  1995cited by this paper
• Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast

  1995influential reference
• An MBoC Favorite: Morphological classification of the yeast vacuolar protein-sorting mutants: evidence for a prevacuolar compartment in class E vps mutants

  1992cited by this paper
• Molecular dissection of the secretory pathway

  1992cited by this paper
• A simple and efficient procedure for transformation of yeasts.

  1992cited by this paper
• Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae

  1990cited by this paper
• Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases

  1988cited by this paper
• Studies on transformation of Escherichia coli with plasmids.

  1983cited by this paper

• Hybrid endosomal coats contain different classes of sorting nexins.

  2026cites this paper
• Hybrid endosomal coats containing different classes of sorting nexins

  2025cites this paper
• Membrane Trafficking in Psychiatric Disorders: Bridging Cellular Dysfunction and Mental Health—A Narrative Review

  2025cites this paper
• Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer

  2024cites this paper
• N-terminal signals in the SNX-BAR paralogs Vps5 and Vin1 guide endosomal coat complex formation

  2024cites this paper
• Characterization of the First Secreted Sorting Nexin Identified in the Leishmania Protists

  2024cites this paper
• Contrasting Retromer with a Newly Described Retriever in Arabidopsis thaliana

  2024cites this paper
• Assembly and fission of tubular carriers mediating protein sorting in endosomes

  2024cites this paper
• Retromer oligomerization drives SNX‐BAR coat assembly and membrane constriction

  2022cites this paper
• The VINE complex is an endosomal VPS9-domain GEF and SNX-BAR coat

  2022cites this paper
• You can go your own way: SNX-BAR coat complexes direct traffic at late endosomes.

  2022cites this paper
• Crystal structure of the PX domain of Vps17p from Saccharomyces cerevisiae.

  2022cites this paper
• The VINE complex is a VPS9-domain GEF-containing SNX-BAR coat involved in endosomal sorting

  2021cites this paper
• The retromer complex regulates C. elegans development and mammalian ciliogenesis

  2021cites this paper
• CROP: a retromer‐PROPPIN complex mediating membrane fission in the endo‐lysosomal system

  2021influential citation
• The Retromer Complex: From Genesis to Revelations.

  2021cites this paper
• Sorting nexins: A novel promising therapy target for cancerous/neoplastic diseases

  2020cites this paper
• Retro Is Cool: Structure of the Versatile Retromer Complex.

  2020cites this paper
• Sorting Nexins in Protein Homeostasis

  2020cites this paper
• Endosomal SNX Proteins are Required for Recycling of the Epithelial Sodium Channel.

  2019cites this paper
• VPS29, a tweak tool of endosomal recycling.

  2019cites this paper
• DNAJC proteins and pathways to parkinsonism

  2019cites this paper
• A bipartite sorting signal ensures specificity of retromer complex in membrane protein recycling

  2019cites this paper
• BAR domain proteins—a linkage between cellular membranes, signaling pathways, and the actin cytoskeleton

  2018cites this paper
• The enigmatic endosome – sorting the ins and outs of endocytic trafficking

  2018influential citation
• Expression and localization of the polarity protein CRB2 in adult mouse brain: a comparison with the CRB1rd8 mutant mouse model

  2018cites this paper
• PtpA, a secreted tyrosine phosphatase from Staphylococcus aureus, contributes to virulence and interacts with coronin-1A during infection

  2018cites this paper
• Emerging Role of Retromer in Modulating Pathogen Growth.

  2018cites this paper
• The retromer, sorting nexins and the plant endomembrane protein trafficking

  2018cites this paper
• Avidity-driven polarity establishment via multivalent lipid-GTPase module interactions

  2018cites this paper
• Cargo selectivity of yeast sorting nexins

  2017cites this paper
• Sorting nexin (MoVps17) is required for fungal development and plant infection by regulating endosome dynamics in the rice blast fungus

  2017cites this paper
• Functional characterization of Leishmania donovani myosin-XXI in transfection and lipid binding studies

  2017cites this paper
• Retromer-driven membrane tubulation separates endosomal recycling from Rab7/Ypt7-dependent fusion

  2017influential citation
• Structure of the PX domain of SNX25 reveals a novel phospholipid recognition model by dimerization in the PX domain

  2017cites this paper
• Overexpression of FAB1A-GFP recruits SNX2b on the endosome membrane in snx1–1 mutant in Arabidopsis

  2016influential citation
• The Retromer Complex

  2016cites this paper
• Retromer-Mediated Protein Sorting and Vesicular Trafficking.

  2016cites this paper
• Retromer in Polarized Protein Transport.

  2016cites this paper
• Molecular Insights into Rab7‐Mediated Endosomal Recruitment of Core Retromer: Deciphering the Role of Vps26 and Vps35

  2015cites this paper
• Formation of Tubulovesicular Carriers from Endosomes and Their Fusion to the trans-Golgi Network.

  2015influential citation
• Retromer‐mediated endosomal protein sorting: The role of unstructured domains

  2015cites this paper
• Retromer: Structure, function, and roles in mammalian disease.

  2015cites this paper
• The retromer complex in development and disease

  2015cites this paper
• Molecular Basis of the Trafficking of Cysteine Proteases and Other Soluble Lysosomal Proteins in Entamoeba histolytica

  2015cites this paper
• Characterization of the Role of WASH on Phagosome Maturation

  2014cites this paper
• Validity and applicability of membrane model systems for studying interactions of peripheral membrane proteins with lipids.

  2014cites this paper
• The role of reversible ubiquitylation in EGF signalling

  2013cites this paper
• CONTROL OF RAB SMALL G-PROTEINS IN YEAST ENDOSOMAL TRAFFIC

  2013cites this paper
• Clathrin is not required for SNX-BAR-retromer-mediated carrier formation

  2013influential citation
• Rab GTPase regulation of retromer-mediated cargo export during endosome maturation

  2012cites this paper
• Mapping the Interactions between a RUN Domain from DENND5/Rab6IP1 and Sorting Nexin 1

  2012cites this paper
• Inhibition of Retromer Activity by Herpesvirus Saimiri Tip Leads to CD4 Downregulation and Efficient T Cell Transformation

  2011cites this paper
• VPS29 Is Not an Active Metallo-Phosphatase but Is a Rigid Scaffold Required for Retromer Interaction with Accessory Proteins

  2011cites this paper
• International Union of Basic and Clinical Pharmacology. LXXXIV: Leukotriene Receptor Nomenclature, Distribution, and Pathophysiological Functions

  2011cites this paper
• Recent Advances in Retromer Biology

  2011cites this paper
• Retromer recycles vacuolar sorting receptors from the trans-Golgi network.

  2010cites this paper
• The role of the retromer complex in receptor trafficking

  2010influential citation
• The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

  2010cites this paper
• The retromer complex.

  2010cites this paper
• Analyses of SORTING NEXINs Reveal Distinct Retromer-Subcomplex Functions in Development and Protein Sorting in Arabidopsis thaliana[C][W]

  2010cites this paper
• env1 Mutant of VPS35 gene exhibits unique protein localization and processing phenotype at Golgi and lysosomal vacuole in Saccharomyces cerevisiae

  2010cites this paper
• Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation

  2010cites this paper
• The Role of Retromer in Neurodegenerative Disease

  2009cites this paper
• Retromer: multipurpose sorting and specialization in polarized transport.

  2008cites this paper
• Membrane recognition by phospholipid-binding domains

  2008cites this paper
• The Structure and Function of the Retromer Protein Complex

  2008cites this paper
• Structure of Vps26B and Mapping of its Interaction with the Retromer Protein Complex

  2008cites this paper
• Functional dissection of alternative secretory pathways in the yeast S. cerevisiae

  2008cites this paper
• Membrane traffic in the secretory pathway

  2008cites this paper
• 1 PHOSPHOINOSITIDE 3-KINASE REGULATES THE ROLE OF RETROMER IN

  2007cites this paper
• Retromer and sorting nexins in development.

  2007cites this paper
• Dominant‐Negative Behavior of Mammalian Vps35 in Yeast Requires a Conserved PRLYL Motif Involved in Retromer Assembly

  2007influential citation
• EHD1 Interacts with Retromer to Stabilize SNX1 Tubules and Facilitate Endosome‐to‐Golgi Retrieval

  2007cites this paper
• Phosphoinositide 3-kinase regulates the role of retromer in transcytosis of the polymeric immunoglobulin receptor.

  2007cites this paper
• The retromer component sorting nexin-1 is required for efficient retrograde transport of Shiga toxin from early endosome to the trans Golgi network

  2007influential citation
• Coated vesicles in plant cells.

  2007cites this paper
• Identification of a conserved motif required for Vps35p/Vps26p interaction and assembly of the retromer complex.

  2007cites this paper
• Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling

  2007cites this paper
• A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer

  2006influential citation
• The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain

  2006cites this paper
• The Phox (PX) domain proteins and membrane traffic.

  2006cites this paper
• Trafficking of primate lentiviral envelope proteins.

  2006cites this paper
• The human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptide.

  2006cites this paper
• Plant Retromer, Localized to the Prevacuolar Compartment and Microvesicles in Arabidopsis, May Interact with Vacuolar Sorting Receptors[W]

  2006cites this paper
• Membrane trafficking as a virulence mechanism of the enteric protozoan parasite Entamoeba histolytica

  2006cites this paper
• Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis.

  2006cites this paper
• Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transport

  2005influential citation
• Plant Prevacuolar Compartments and Endocytosis

  2005cites this paper
• Recycle your receptors with retromer.

  2005cites this paper
• A retromerlike complex is a novel Rab7 effector that is involved in the transport of the virulence factor cysteine protease in the enteric protozoan parasite Entamoeba histolytica.

  2005cites this paper
• Crystal Structure of Human Vacuolar Protein Sorting Protein 29 Reveals a Phosphodiesterase/Nuclease-like Fold and Two Protein-Protein Interaction Sites*

  2005cites this paper
• Trafficking of viral membrane proteins.

  2005cites this paper
• Sorting nexin 17 facilitates LRP recycling in the early endosome

  2005cites this paper
• Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly

  2005cites this paper
• Sorting nexin homologues are targets of phosphatidylinositol 3‐phosphate in sporulation of Schizosaccharomyces pombe

  2004cites this paper
• Arabidopsis mu A-adaptin interacts with the tyrosine motif of the vacuolar sorting receptor VSR-PS1.

  2004cites this paper
• A Structural Requirement for Processing the Cardiac K+ Channel KCNQ1*

  2004cites this paper
• The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor

  2004cites this paper
• The Phox Homology (PX) Domain Protein Interaction Network in Yeast*S

  2004cites this paper