Normal motor learning during pharmacological prevention of Purkinje cell long-term depression.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2005-11-22

• Fields of study

  Medicine

• Identifiers
  DOI 10.1073/PNAS.0508191102PMID 16278298PMCID PMC1288000
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Differential expression of T-type calcium channels in P/Q-type calcium channel mutant mice with ataxia and absence epilepsy.

  2005cited by this paper
• Is autism due to brain desynchronization?

  2005cited by this paper
• Purkinje cell long-term depression is prevented by T-588, a neuroprotective compound that reduces cytosolic calcium release from intracellular stores.

  2005cited by this paper
• T-588 Protects Motor Neuron Death Following Axotomy

  2004cited by this paper
• Parallel fibre stimulation and the responses induced thereby in the Purkinje cells of the cerebellum

  2004cited by this paper
• Increased expression of P/Q-type Ca2+ channel α1A subunit mRNA in cerebellum of N-type Ca2+ channel α1B subunit gene-deficient mice

  2004cited by this paper
• Increased expression of P/Q-type Ca2+ channel alpha1A subunit mRNA in cerebellum of N-type Ca2+ channel alpha1B subunit gene-deficient mice.

  2004cited by this paper
• Cerebellar LTD and Learning-Dependent Timing of Conditioned Eyelid Responses

  2003cited by this paper
• Deformation of Network Connectivity in the Inferior Olive of Connexin 36-Deficient Mice Is Compensated by Morphological and Electrophysiological Changes at the Single Neuron Level

  2003cited by this paper
• Activity-independent homeostasis in rhythmically active neurons.

  2003cited by this paper
• Optical Imaging of Long-Term Depression in the Mouse Cerebellar Cortex In Vivo

  2003cited by this paper
• Mutations in High-Voltage-Activated Calcium Channel Genes Stimulate Low-Voltage-Activated Currents in Mouse Thalamic Relay Neurons

  2002cited by this paper
• Why do Purkinje cells die so easily after global brain ischemia? Aldolase C, EAAT4, and the cerebellar contribution to posthypoxic myoclonus.

  2002cited by this paper
• Regional patterns of compensation following genetic deletion of either 5-hydroxytryptamine(1A) or 5-hydroxytryptamine(1B) receptor in the mouse.

  2001cited by this paper
• Ameliorative effects of a cognitive enhancer, T-588, on place learning deficits induced by transient forebrain ischemia in rats.

  2001cited by this paper
• Expression of Protein Kinase C Inhibitor Blocks Cerebellar Long-Term Depression without Affecting Purkinje Cell Excitability in Alert Mice

  2001cited by this paper
• Cerebellar long-term depression: characterization, signal transduction, and functional roles.

  2001cited by this paper
• Kinetic and frequency-domain properties of reflex and conditioned eyelid responses in the rabbit.

  2000cited by this paper
• Reduced facilitation and vesicular uptake in crustacean and mammalian neuromuscular junction by T-588, a neuroprotective compound.

  1999cited by this paper
• Some organizing principles for the control of movement based on olivocerebellar physiology.

  1997cited by this paper
• Dynamic organization of motor control within the olivocerebellar system

  1995cited by this paper
• Cerebellar cortex lesions disrupt learning-dependent timing of conditioned eyelid responses

  1993cited by this paper
• Changes in the motor pattern of learned and unlearned responses following cerebellar lesions: a kinematic analysis of the nictitating membrane reflex.

  1992cited by this paper
• Motor control : concepts and issues

  1991cited by this paper
• Eyeblink conditioning in rats.

  1990cited by this paper
• Stimulation parameters influencing climbing fibre induced long-term depression of parallel fibre synapses.

  1989cited by this paper
• Long-lasting depression of parallel fiber-Purkinje cell transmission induced by conjunctive stimulation of parallel fibers and climbing fibers in the cerebellar cortex.

  1982cited by this paper
• Eighteenth Bowditch lecture. Motor aspects of cerebellar control.

  1974cited by this paper
• A theory of cerebellar cortex

  1969cited by this paper
• Classical conditioning of the rabbit's nictitating membrane response at backward, simultaneous, and forward CS-US intervals.

  1969cited by this paper
• CS-US interval and US intensity in classical conditioning of the rabbit's nictitating membrane response.

  1968cited by this paper
• The excitatory synaptic action of climbing fibres on the Purkinje cells of the cerebellum

  1966cited by this paper

• Consensus Paper: Models of Cerebellar Functions

  2026cites this paper
• The Role of Cerebellar Intrinsic Neuronal Excitability, Synaptic Plasticity, and Perineuronal Nets in Eyeblink Conditioning

  2024cites this paper
• Impact of enriched environment on motor performance and learning in mice

  2024cites this paper
• Positive feedback of efferent copy via pontine nucleus facilitates cerebellum-mediated associative learning.

  2023cites this paper
• Synaptic Mechanisms of Delay Eyeblink Classical Conditioning: AMPAR Trafficking and Gene Regulation in an In Vitro Model

  2023cites this paper
• The molecular memory code and synaptic plasticity: A synthesis

  2022cites this paper
• Role of the Cerebellum in the Acquisition and Consolidation of Memory of Motor Learning

  2021cites this paper
• Purkinje Neurons: Synaptic Plasticy

  2021cites this paper
• University of Birmingham Gating by Memory

  2021cites this paper
• Gating by Memory: a Theory of Learning in the Cerebellum

  2021cites this paper
• University of Birmingham Gating by Memory

  2021cites this paper
• Evolution of the Marr-Albus-Ito Model

  2021cites this paper
• The Shape of Data: a Theory of the Representation of Information in the Cerebellar Cortex

  2021cites this paper
• Synaptic protein interaction networks encode experience by assuming stimulus-specific and brain-region-specific states

  2021cites this paper
• Timing in Purkinje Cells and a Novel Learning Mechanism

  2021cites this paper
• Contribution of Norepinephrine to Cerebellar Long-Term Depression and Motor Learning

  2021cites this paper
• Synaptic signaling networks encode experience by assuming stimulus-specific and brain-region-specific states

  2021cites this paper
• W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34

  2021cites this paper
• Synergism of type 1 metabotropic and ionotropic glutamate receptors in cerebellar molecular layer interneurons in vivo

  2020cites this paper
• Behavioral Tests for Mouse Models of Autism: An argument for the inclusion of cerebellum-controlled motor behaviors.

  2020cites this paper
• Norepinephrine facilitates induction of long-term depression through β-adrenergic receptor at parallel fiber-to-Purkinje cell synapses in the flocculus.

  2020cites this paper
• Is Purkinje Neuron Hyperpolarisation Important for Cerebellar Synaptic Plasticity? A Retrospective and Prospective Analysis

  2020cites this paper
• Ocular Reflex Adaptation as an Experimental Model of Cerebellar Learning -- In Memory of Masao Ito -.

  2020cites this paper
• The Optogenetic Revolution in Cerebellar Investigations

  2020cites this paper
• 50 years since the Marr, Ito, and Albus models of the cerebellum.

  2020cites this paper
• SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning–specific memory traces

  2020cites this paper
• Inactivation of the interpositus nucleus during unpaired extinction does not prevent extinction of conditioned eyeblink responses or conditioning-specific reflex modification.

  2019cites this paper
• Intrinsic memory of temporal intervals in cerebellar Purkinje cells.

  2019cites this paper
• The Concept of Transmission Coefficient Among Different Cerebellar Layers: A Computational Tool for Analyzing Motor Learning

  2019cites this paper
• Complex spike clusters and false‐positive rejection in a cerebellar supervised learning rule

  2019cites this paper
• Neuroprotective effect of CuATSM on neurotoxin-induced motor neuron loss in an ALS mouse model.

  2019cites this paper
• The Anatomy and Physiology of Eyeblink Classical Conditioning.

  2018cites this paper
• Occurrence of long-term depression in the cerebellar flocculus during adaptation of optokinetic response

  2018cites this paper
• Impact of parallel fiber to Purkinje cell long-term depression is unmasked in absence of inhibitory input

  2018cites this paper
• The negotiated equilibrium model of spinal cord function

  2018cites this paper
• Depressed by Learning—Heterogeneity of the Plasticity Rules at Parallel Fiber Synapses onto Purkinje Cells

  2018cites this paper
• 7th Symposium of SRC LTD, RP and motor learning

  2018cites this paper
• Absence of Parallel Fibre to Purkinje Cell LTD During Eyeblink Conditioning

  2018cites this paper
• The Roles of the Olivocerebellar Pathway in Motor Learning and Motor Control. A Consensus Paper

  2017cites this paper
• Does the Cerebellum Contribute to Human Navigation by Processing Sequential Information?

  2017cites this paper
• Protein Kinase Mzeta (PKM-zeta) Regulates Kv1.2 Dependent Cerebellar Eyeblink Classical Conditioning

  2017cites this paper
• Procedural Learning: VOR

  2017cites this paper
• Chronic imaging of movement-related Purkinje cell calcium activity in awake behaving mice.

  2016cites this paper
• Intracellular Ca(2+) thresholds for induction of excitatory long-term depression and inhibitory long-term potentiation in a cerebellar Purkinje neuron.

  2016cites this paper
• Non-canonical Signaling, the Hidden Life of Ligand-Gated Ion Channels.

  2016cites this paper
• Plasticity within non-cerebellar pathways rapidly shapes motor performance in vivo

  2016cites this paper
• The inferior olive is essential for long-term maintenance of a simple motor skill.

  2016cites this paper
• Title Long-term Potentiation of Inhibitory Synaptic Transmission onto Cerebellar Purkinje Neurons Contributes to Adaptation of Vestibulo-Ocular Reflex

  2016cites this paper
• Classical Conditioning of Timed Motor Responses

  2016cites this paper
• Ablation of the inferior olive prevents H-reflex down-conditioning in rats.

  2016cites this paper
• Bergmann Glia, Long-Term Depression, and Autism Spectrum Disorder

  2016cites this paper
• Excitatory Cerebellar Nucleocortical Circuit Provides Internal Amplification during Associative Conditioning

  2016cites this paper
• LTD, RP, and Motor Learning

  2016cites this paper
• The diverse branches of PTPRR protein tyrosine phosphatase function. New insights in cell differentiation, neuronal signalling and mouse behaviour

  2016cites this paper
• Evolving Models of Pavlovian Conditioning: Cerebellar Cortical Dynamics in Awake Behaving Mice

  2015cites this paper
• Stochastic Synchronization in Purkinje Cells with Feedforward Inhibition Could Be Studied with Equivalent Phase-Response Curves

  2015influential citation
• Activation of a Temporal Memory in Purkinje Cells by the mGluR7 Receptor.

  2015cites this paper
• The challenge of understanding the brain: where we stand in 2015.

  2015cites this paper
• The neural circuitry and molecular mechanisms underlying delay and trace eyeblink conditioning in mice.

  2015cites this paper
• Motor Learning and the Cerebellum.

  2015cites this paper
• Oscillations, Timing, Plasticity, and Learning in the Cerebellum

  2015cites this paper
• Timing in the cerebellum : a matter of network inhibition

  2015cites this paper
• Motor Learning and the Cerebellum

  2015cites this paper
• Synapses need coordination to learn motor skills

  2014cites this paper
• Around LTD Hypothesis in Motor Learning

  2014cites this paper
• Gating of neural error signals during motor learning

  2014cites this paper
• How stochastic synchrony could work in cerebellar Purkinje cells

  2014influential citation
• Neutralization of Nogo-A Enhances Synaptic Plasticity in the Rodent Motor Cortex and Improves Motor Learning in Vivo

  2014cites this paper
• Regulation and functional roles of rebound potentiation at cerebellar stellate cell—Purkinje cell synapses

  2014cites this paper
• Long-term depression as a model of cerebellar plasticity.

  2014cites this paper
• Motor learning in common marmosets: vestibulo-ocular reflex adaptation and its sensitivity to inhibitors of Purkinje cell long-term depression.

  2014cites this paper
• Learning-induced structural plasticity in the cerebellum.

  2014cites this paper
• Long-term Potentiation of Inhibitory Synaptic Transmission onto Cerebellar Purkinje Neurons Contributes to Adaptation of Vestibulo-Ocular Reflex

  2013cites this paper
• Purkinje Neurons: Synaptic Plasticy

  2013cites this paper
• Children with autism spectrum disorders show abnormal conditioned response timing on delay, but not trace, eyeblink conditioning.

  2013cites this paper
• Long-term depression and other synaptic plasticity in the cerebellum

  2013cites this paper
• Gating of long‐term depression by Ca2+/calmodulin‐dependent protein kinase II through enhanced cGMP signalling in cerebellar Purkinje cells

  2013cites this paper
• Motor Skill Training Induces Coordinated Strengthening and Weakening between Neighboring Synapses

  2013cites this paper
• Distinct cerebellar engrams in short-term and long-term motor learning

  2013cites this paper
• Dendritic SK channels convert NMDA-R-dependent LTD to burst timing-dependent plasticity.

  2013cites this paper
• Classical conditioning of motor responses: What is the learning mechanism?

  2013cites this paper
• The cerebellum: a new key structure in the navigation system

  2013cites this paper
• Cerebellar LTD vs. motor learning - Lessons learned from studying GluD2

  2013cites this paper
• An agonist–antagonist cerebellar nuclear system controlling eyelid kinematics during motor learning

  2012cites this paper
• A late phase of LTD in cultured cerebellar Purkinje cells requires persistent dynamin-mediated endocytosis.

  2012cites this paper
• Cellular Mechanisms and Behavioral Consequences of Kv1.2 Regulation in the Rat Cerebellum

  2012cites this paper
• Impact of Signaling and Plasticity on Cerebellar Function and Memory Formation

  2012cites this paper
• Deranged Calcium Signaling in Purkinje Cells and Pathogenesis in Spinocerebellar Ataxia 2 (SCA2) and Other Ataxias

  2012cites this paper
• Synaptic dynamics and long-term plasticity at synapses of Purkinje cells onto neighboring Purkinje cells of a mormyrid fish: a dual cell recording study.

  2012cites this paper
• Reevaluating the role of LTD in cerebellar motor learning.

  2011influential citation
• Motoring ahead with rodents.

  2011cites this paper
• Role of Calcium in Cerebellar Learning and Function

  2011cites this paper
• A new method for modulating the activity of parvalbumin- positive neurons and cerebellar Purkinje cells in vivo

  2011cites this paper
• Impact of Afferent Inputs on Purkinje Cell Spiking Patterns and Motor Coordination

  2011cites this paper
• The Cerebellum: Brain for an Implicit Self

  2011cites this paper
• Catalytic Asymmetric Hydrogenation of Ethyl 2-(Benzo[b]thiophen-5-yl)-2-oxoacetate with Ru-SunPhos in the Formal Synthesis of T-588

  2011cites this paper
• Cerebellar motor learning versus cerebellar motor timing: the climbing fibre story

  2011cites this paper
• Synaptic mechanisms of sensorimotor learning in the cerebellum.

  2011cites this paper
• Long-term depression in the CNS

  2010cites this paper
• Presynaptic plasticity at cerebellar parallel fiber terminals.

  2010cites this paper