Perspective and potential of oral lipid-based delivery to optimize pharmacological therapies against cardiovascular diseases.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of Controlled Release

• Publication date

  2014-11-10

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.jconrel.2014.05.013PMID 24852093
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• First in man bioavailability and tolerability studies of a silica–lipid hybrid (Lipoceramic) formulation: a Phase I study with ibuprofen

  2014cited by this paper
• Synergistic role of self-emulsifying lipids and nanostructured porous silica particles in optimizing the oral delivery of lovastatin.

  2014cited by this paper
• Tableting lipid-based formulations for oral drug delivery: a case study with silica nanoparticle-lipid-mannitol hybrid microparticles.

  2013cited by this paper
• Compritol®888 ATO a lipid excipient for sustained release of highly water soluble active: formulation, scale-up and IVIVC study.

  2013cited by this paper
• Coenzyme Q10 oral bioavailability: effect of formulation type

  2013cited by this paper
• Self nanoemulsifying drug delivery system (SNEDDS) of rosuvastatin calcium: design, formulation, bioavailability and pharmacokinetic evaluation.

  2013cited by this paper
• Recent developments in oral lipid-based drug delivery

  2013cited by this paper
• Characterization of semi-solid Self-Emulsifying Drug Delivery Systems (SEDDS) of atorvastatin calcium by Raman image spectroscopy and chemometrics.

  2013cited by this paper
• Transforming Lipid-Based Oral Drug Delivery Systems into Solid Dosage Forms: An Overview of Solid Carriers, Physicochemical Properties, and Biopharmaceutical Performance

  2013cited by this paper
• Combination pharmacotherapy to prevent cardiovascular disease: present status and challenges.

  2013cited by this paper
• Formulation and evaluation of novel solid lipid microparticles as a sustained release system for the delivery of metformin hydrochloride

  2013cited by this paper
• Liposomal Amiodarone Augments Anti-arrhythmic Effects and Reduces Hemodynamic Adverse Effects in an Ischemia/Reperfusion Rat Model

  2013cited by this paper
• Silica-lipid hybrid (SLH) formulations enhance the oral bioavailability and efficacy of celecoxib: An in vivo evaluation.

  2013cited by this paper
• Lipid nanoparticles as carrier for octyl-methoxycinnamate: in vitro percutaneous absorption and photostability studies.

  2012cited by this paper
• Assembling nanoparticle coatings to improve the drug delivery performance of lipid based colloids.

  2012cited by this paper
• Supersaturated Self-Nanoemulsifying Drug Delivery Systems (super-SNEDDS)

  2012cited by this paper
• Nanoemulsions as self-emulsified drug delivery carriers for enhanced permeability of the poorly water-soluble selective β₁-adrenoreceptor blocker Talinolol.

  2012cited by this paper
• Design and evaluation of polymer coated carvedilol loaded solid lipid nanoparticles to improve the oral bioavailability: a novel strategy to avoid intraduodenal administration.

  2012cited by this paper
• Hybrid nanomaterials that mimic the food effect: controlling enzymatic digestion for enhanced oral drug absorption.

  2012cited by this paper
• Solid lipid nanoparticles loading candesartan cilexetil enhance oral bioavailability: in vitro characteristics and absorption mechanism in rats.

  2012cited by this paper
• In situ intestinal permeability and in vivo absorption characteristics of olmesartan medoxomil in self-microemulsifying drug delivery system

  2012cited by this paper
• Food-Drug Interactions

  2012cited by this paper
• Multifunctional nanocapsules for simultaneous encapsulation of hydrophilic and hydrophobic compounds and on-demand release.

  2012cited by this paper
• Nanostructured Silica–Lipid Hybrid Microparticles: A Supersaturating Carrier for Water- and Lipid-resistant Compounds

  2012cited by this paper
• Lipid-based formulations for oral delivery of lipophilic drugs.

  2012cited by this paper
• An Excellent Delivery System for Improving the Oral Bioavailability of Natural Vitamin E in Rats

  2012cited by this paper
• Nanoemulsions versus microemulsions: terminology, differences, and similarities

  2012cited by this paper
• Enhancement of Intestinal Permeability Utilizing Solid Lipid Nanoparticles Increases γ-Tocotrienol Oral Bioavailability

  2012cited by this paper
• Development, Optimization, and Characterization of Solid Self-Nanoemulsifying Drug Delivery Systems of Valsartan Using Porous Carriers

  2012cited by this paper
• Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: basic approaches and practical applications.

  2011cited by this paper
• Formulation of Self-Nanoemulsifying Drug Delivery System for Telmisartan with Improved Dissolution and Oral Bioavailability

  2011cited by this paper
• Applications of Biotechnology in Cardiovascular Therapeutics

  2011cited by this paper
• Self-microemulsifying drug delivery system for improved oral bioavailability of dipyridamole: Preparation and evaluation

  2011cited by this paper
• Global status report on noncommunicable diseases 2010.

  2011cited by this paper
• Silica-Lipid Hybrid (SLH) Versus Non-lipid Formulations for Optimising the Dose-Dependent Oral Absorption of Celecoxib

  2011cited by this paper
• Effects of non-ionic surfactants on cytochrome P450-mediated metabolism in vitro.

  2011cited by this paper
• Nanoemulsion improves the oral absorption of candesartan cilexetil in rats: Performance and mechanism.

  2011cited by this paper
• Design and development of a self-nanoemulsifying drug delivery system for telmisartan for oral drug delivery

  2011cited by this paper
• Nanostructured lipid carrier versus solid lipid nanoparticles of simvastatin: comparative analysis of characteristics, pharmacokinetics and tissue uptake.

  2011cited by this paper
• Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: physicochemical characterization and pharmacokinetics.

  2010cited by this paper
• Solid self-emulsifying nitrendipine pellets: preparation and in vitro/in vivo evaluation.

  2010cited by this paper
• Self-nanoemulsifying drug delivery systems: formulation insights, applications and advances.

  2010cited by this paper
• Improved pH-independent dissolution and oral absorption of valsartan via the preparation of solid dispersion

  2010cited by this paper
• Colloidal nanocarriers: a review on formulation technology, types and applications toward targeted drug delivery.

  2010cited by this paper
• Phospholipids and Lipid-Based Formulations in Oral Drug Delivery

  2010cited by this paper
• New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

  2010cited by this paper
• Structured emulsion-based delivery systems: controlling the digestion and release of lipophilic food components.

  2010cited by this paper
• Lipid--an emerging platform for oral delivery of drugs with poor bioavailability.

  2009cited by this paper
• Nanostructure of liquid crystalline matrix determines in vitro sustained release and in vivo oral absorption kinetics for hydrophilic model drugs.

  2009cited by this paper
• Doxorubicin and paclitaxel-loaded lipid-based nanoparticles overcome multidrug resistance by inhibiting P-glycoprotein and depleting ATP.

  2009cited by this paper
• Silica-lipid hybrid (SLH) microcapsules: a novel oral delivery system for poorly soluble drugs.

  2009cited by this paper
• Preparation and Characterization of Oil in Water Nano-Reservoir Systems for Improved Oral Delivery of Atorvastatin

  2009cited by this paper
• Relative bioavailability comparison of different coenzyme Q10 formulations with a novel delivery system.

  2009cited by this paper
• Dry hybrid lipid-silica microcapsules engineered from submicron lipid droplets and nanoparticles as a novel delivery system for poorly soluble drugs.

  2009cited by this paper
• Glyceryl Monooleate/Poloxamer 407 Cubic Nanoparticles as Oral Drug Delivery Systems: I. In Vitro Evaluation and Enhanced Oral Bioavailability of the Poorly Water-Soluble Drug Simvastatin

  2009cited by this paper
• Effect of poloxamer 188 on lymphatic uptake of carvedilol-loaded solid lipid nanoparticles for bioavailability enhancement

  2009cited by this paper
• Solubilized formulation of olmesartan medoxomil for enhancing oral bioavailability

  2009cited by this paper
• Effect of lipid core material on characteristics of solid lipid nanoparticles designed for oral lymphatic delivery.

  2009cited by this paper
• Cytochrome P450-mediated metabolism in the human gut wall.

  2009cited by this paper
• Enhanced oral bioavailability of Coenzyme Q10 by self-emulsifying drug delivery systems.

  2009cited by this paper
• Comparison of self-microemulsifying drug delivery system versus solid dispersion technology used in the improvement of dissolution rate and bioavailability of vinpocetine.

  2009cited by this paper
• Formulation and in vivo evaluation of self-nanoemulsifying granules for oral delivery of a combination of ezetimibe and simvastatin.

  2008cited by this paper
• Multi-functional nanocarriers for targeted delivery of drugs and genes.

  2008cited by this paper
• Formulation and In Vivo Evaluation of Self-Nanoemulsifying Granules for Oral Delivery of a Combination of Ezetimibe and Simvastatin

  2008cited by this paper
• Lipid-based systems for the enhanced delivery of poorly water soluble drugs.

  2008cited by this paper
• Redispersible, dry emulsion of lovastatin protects against intestinal metabolism and improves bioavailability

  2008cited by this paper
• Arterial compliance and vitamin E blood levels with a self emulsifying preparation of tocotrienol rich vitamin E

  2008cited by this paper
• Nanoscale double emulsions stabilized by single-component block copolypeptides

  2008cited by this paper
• Challenges and opportunities in the encapsulation of liquid and semi-solid formulations into capsules for oral administration.

  2008cited by this paper
• Effects of intestinal constituents and lipids on intestinal formation and pharmacokinetics of desethylamiodarone formed from amiodarone

  2008cited by this paper
• Towards Quantitative Prediction of Oral Drug Absorption

  2008cited by this paper
• Current Methods for Predicting Human Food Effect

  2008cited by this paper
• Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

  2007cited by this paper
• Lipid excipients Peceol and Gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within Caco-2 cells.

  2007cited by this paper
• Lipid-based colloidal carriers for peptide and protein delivery – liposomes versus lipid nanoparticles

  2007cited by this paper
• Impact of cremophor-EL and polysorbate-80 on digoxin permeability across rat jejunum: delineation of thermodynamic and transporter related events using the reciprocal permeability approach.

  2007cited by this paper
• Preparation, characterization, and in vitro and in vivo evaluation of lovastatin solid lipid nanoparticles

  2007cited by this paper
• Development and evaluation of nitrendipine loaded solid lipid nanoparticles: influence of wax and glyceride lipids on plasma pharmacokinetics.

  2007cited by this paper
• Clinical studies with oral lipid based formulations of poorly soluble compounds

  2007cited by this paper
• Predicting Effect of Food on Extent of Drug Absorption Based on Physicochemical Properties

  2007cited by this paper
• Lipid-based delivery systems and intestinal lymphatic drug transport: A mechanistic update

  2007cited by this paper
• A lipid-based liquid crystalline matrix that provides sustained release and enhanced oral bioavailability for a model poorly water soluble drug in rats.

  2007cited by this paper
• Development and validation of a preclinical food effect model.

  2007cited by this paper
• Lipid formulation strategies for enhancing intestinal transport and absorption of P-glycoprotein (P-gp) substrate drugs: in vitro/in vivo case studies.

  2007cited by this paper
• Solid lipid nanoparticles as a drug delivery system for peptides and proteins.

  2007cited by this paper
• Improvement in intestinal coenzyme q10 absorption by food intake.

  2007cited by this paper
• Predicting Effect of Food on Extent of Drug Absorption Based on Physicochemical Properties

  2007cited by this paper
• Mechanism of inhibition of P-glycoprotein mediated efflux by vitamin E TPGS: influence on ATPase activity and membrane fluidity.

  2007cited by this paper
• Combination therapy with statins and omega-3 fatty acids.

  2006cited by this paper
• Improvement of bioavailability and photostability of amlodipine using redispersible dry emulsion.

  2006cited by this paper
• Pharmacokinetics, tissue distribution and bioavailability of nitrendipine solid lipid nanoparticles after intravenous and intraduodenal administration

  2006cited by this paper
• Preparation and evaluation of self‐microemulsifying drug delivery systems (SMEDDS) containing atorvastatin

  2006cited by this paper
• The Effects of Food on the Bioavailability of Fenofibrate Administered Orally in Healthy Volunteers via Sustained-Release Capsule

  2006cited by this paper
• Photostabilization of 1,4-dihydropyridine antihypertensives by incorporation into beta-cyclodextrin and liposomes.

  2006cited by this paper
• Role of efflux pumps and metabolising enzymes in drug delivery

  2005cited by this paper
• Pharmacokinetics, tissue distribution and bioavailability of clozapine solid lipid nanoparticles after intravenous and intraduodenal administration.

  2005cited by this paper
• Preparation and Evaluation of SEDDS and SMEDDS Containing Carvedilol

  2005cited by this paper
• Evaluation of a chylomicron flow blocking approach to investigate the intestinal lymphatic transport of lipophilic drugs.

  2005cited by this paper
• Accelerated photostability study of tretinoin and isotretinoin in liposome formulations.

  2005cited by this paper
• Influence of a Fat-Rich Meal on the Pharmacokinetics of a New Oral Formulation of Cyclosporine in a Crossover Comparison with the Market Formulation

  2004cited by this paper

• Advances in nanostructured drug delivery systems for cardiovascular therapeutics

  2025cites this paper
• Fillable Magnetic Microrobots for Drug Delivery to Cardiac Tissues In Vitro

  2024cites this paper
• Edible Coatings: Classification, applications and innovations in food preservation

  2024cites this paper
• Application of nanoparticles in the diagnosis and treatment of chronic kidney disease

  2023cites this paper
• Food–drug interactions and their implications on oral drug bioavailability

  2022cites this paper
• Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

  2022cites this paper
• Rationale utilization of phospholipid excipients: a distinctive tool for progressing state of the art in research of emerging drug carriers

  2022cites this paper
• Flaxseed-derived peptide, IPPF, inhibits intestinal cholesterol absorption in Caco-2 cells and hepatic cholesterol synthesis in HepG2 cells.

  2021cites this paper
• Design and Characterization of Elastic Artificial Skin Containing Adenosine-Loaded Solid Lipid Nanoparticles for Treating Wrinkles

  2020cites this paper
• Nanoparticle-Based Drug Delivery Systems for Cardiovascular Applications

  2019cites this paper
• Recent Advances in Understanding the Pathogenesis of Cardiovascular Diseases and Development of Treatment Modalities.

  2019cites this paper
• Food for thought: formulating away the food effect – a PEARRL review

  2019cites this paper
• Labrasol-Enriched Nanoliposomal Formulation: Novel Approach to Improve Oral Absorption of Water-Insoluble Drug, Carvedilol

  2018cites this paper
• Comparative Anti-Angiogenesis Study between Allicin Nanoparticle and Normal Allicin from Garlic (Allium Sativum Linn)

  2018cites this paper
• Eplerenone nanoemulsions for treatment of hypertension. Part I: Experimental design for optimization of formulations and physical characterization

  2018cites this paper
• Επιφανειακά τροποποιημένοι νανοράβδοι χρυσού για την στοχευμένη χορήγηση αντικαρκινικών ουσιών

  2018cites this paper
• Prospectives of Antihypertensive Nano-ceuticals as Alternative Therapeutics.

  2017cites this paper
• The Efficacy of Danshe n Injection as Adjunctive Therapy in Treating Angina Pectoris

  2017cites this paper
• Review and analysis of FDA approved drugs using lipid-based formulations

  2017cites this paper
• Nanocarriers as alternative strategies for treatment of mycobacterial infections

  2017cites this paper
• Drug Delivery and Nanoformulations for the Cardiovascular System.

  2017influential citation
• Selection of excipients for the development of carvedilol loaded lipid-based drug delivery systems

  2017cites this paper
• Self-Assembled Lipid Nanoparticles for Oral Delivery of Heparin-Coated Iron Oxide Nanoparticles for Theranostic Purposes

  2017cites this paper
• The Efficacy of Danshen Injection as Adjunctive Therapy in Treating Angina Pectoris: A Systematic Review and Meta-Analysis.

  2017cites this paper
• Polymer-lipid hybrid systems: merging the benefits of polymeric and lipid-based nanocarriers to improve oral drug delivery

  2016cites this paper
• Evaluation of carvedilol compatibility with lipid excipients for the development of lipid-based drug delivery systems

  2016cites this paper
• Oral nanomedicine approaches for the treatment of psychiatric illnesses.

  2016cites this paper
• Silica encapsulated lipid-based drug delivery systems for reducing the fed/fasted variations of ziprasidone in vitro.

  2016cites this paper
• Targeted Drug Delivery for Cardiovascular and Cerebrovascular Diseases.

  2016cites this paper
• Mechanical Force-Triggered Drug Delivery.

  2016cites this paper
• A comparative physicochemical, morphological and magnetic study of silane-functionalized superparamagnetic iron oxide nanoparticles prepared by alkaline coprecipitation.

  2016cites this paper
• Impact of solidification on the performance of lipid-based colloidal carriers: oil-based versus self-emulsifying systems.

  2015cites this paper
• Nano-constructed Carriers Loaded With Antioxidant: Boon For Cardiovascular System.

  2015cites this paper
• Nanomaterial Based Approaches for the Diagnosis and Therapy of Cardiovascular Diseases.

  2015cites this paper
• A New Type of Liquid Silymarin Proliposome Containing Bile Salts: Its Preparation and Improved Hepatoprotective Effects

  2015cites this paper