The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc02517b Click here for additional data file.

Reaction network starting from monomer mixtures of Aβ40 and Aβ42. Interaction at the level of primary nucleation only accelerates Aβ40 fibril formation. Separate fibrils form as secondary nucleation and elongation are highly specific.

• Publication year

  2015

• Venue

  Chemical Science

• Publication date

  2015-05-08

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1039/c4sc02517bPMID 29218188PMCID 5707514
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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