Integrin signaling: the platelet paradigm.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Blood

• Publication date

  1998-04-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1182/BLOOD.V91.8.2645.2645_2645_2657PMID 9531572
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Exposure of ligand-binding sites on platelet integrin α IIB / β 3 by phosphorylation of the β 3 subunit

  1998cited by this paper
• RhoA and the Function of Platelet Integrin αIIbβ3

  1998cited by this paper
• Rack1, a Receptor for Activated Protein Kinase C, Interacts with Integrin β Subunit*

  1998cited by this paper
• Integrin signalling and tyrosine phosphorylation: just the FAKs?

  1998cited by this paper
• Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3.

  1997cited by this paper
• Defective platelet activation in G alpha(q)-deficient mice.

  1997cited by this paper
• Tyrosine Phosphorylation of the Novel Protein-tyrosine Kinase RAFTK during an Early Phase of Platelet Activation by an Integrin Glycoprotein IIb-IIIa-independent Mechanism*

  1997cited by this paper
• Localization of the transmembrane 4 superfamily (TM4SF) member PETA-3 (CD151) in normal human tissues: comparison with CD9, CD63, and alpha5beta1 integrin.

  1997cited by this paper
• Wound Healing--Aiming for Perfect Skin Regeneration

  1997influential reference
• The Fc receptor γ‐chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen

  1997cited by this paper
• Tyrosine Phosphorylation and Relocation of SHIP Are Integrin-mediated in Thrombin-stimulated Human Blood Platelets*

  1997cited by this paper
• Negative regulation of mitogen-activated protein kinase activation by integrin alphaIIbbeta3 in platelets.

  1997cited by this paper
• Isolation of a Novel β4 Integrin-binding Protein (p27BBP) Highly Expressed in Epithelial Cells*

  1997cited by this paper
• The Platelet Antigens CD9, CD42 and Integrin αIIbβIIIa Can be Topographically Associated and Transduce Functionally Similar Signals

  1997cited by this paper
• Integrin-dependent tyrosine phoshorylation and cytoskeletal translocation of Tec in thrombin-activated platelets.

  1997cited by this paper
• Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor γ‐chain

  1997cited by this paper
• Calreticulin-integrin bidirectional signaling complex.

  1997cited by this paper
• Localization of the Transmembrane 4 Superfamily (TM4SF) Member PETA-3 (CD151) in Normal Human Tissues: Comparison with CD9, CD63, and α5β1 Integrin

  1997cited by this paper
• Co-localization of CD9 and GPIIb-IIIa (alpha IIb beta 3 integrin) on activated platelet pseudopods and alpha-granule membranes.

  1997cited by this paper
• UPDATE: PH Domains--A Universal Membrane Adapter

  1997cited by this paper
• Effects of fluid dynamic forces on vascular cell adhesion.

  1997cited by this paper
• Integrin-dependent translocation of p160ROCK to cytoskeletal complex in thrombin-stimulated human platelets.

  1997cited by this paper
• Cell adhesion in vascular biology. New insights into integrin-ligand interaction.

  1997cited by this paper
• The molecular structure of cell adhesion molecules.

  1997cited by this paper
• NAG-2, a Novel Transmembrane-4 Superfamily (TM4SF) Protein That Complexes with Integrins and Other TM4SF Proteins*

  1997cited by this paper
• Regulation of the pp72syk protein tyrosine kinase by platelet integrin αIIbβ3

  1997cited by this paper
• Identification of a Novel Calcium-binding Protein That Interacts with the Integrin αIIb Cytoplasmic Domain*

  1997cited by this paper
• Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion

  1997cited by this paper
• New insights into integrin-ligand interaction.

  1997cited by this paper
• Integrin signaling in vascular biology.

  1997cited by this paper
• Generation of monoclonal antibodies to integrin-associated proteins. Evidence that alpha3beta1 complexes with EMMPRIN/basigin/OX47/M6.

  1997cited by this paper
• Signalling and adhesive properties of the integrin leucocyte function-associated antigen 1 (LFA-1).

  1997cited by this paper
• Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway.

  1997cited by this paper
• Activation of ADP Receptors and Platelet Function

  1997cited by this paper
• Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain.

  1997cited by this paper
• Truncation of the cytoplasmic domain of beta3 in a variant form of Glanzmann thrombasthenia abrogates signaling through the integrin alpha(IIb)beta3 complex.

  1997cited by this paper
• A Collagen-Like Peptide Stimulates Tyrosine Phosphorylation of syk and Phospholipase Cγ2 in Platelets Independent of the Integrin α2β1

  1997cited by this paper
• Folding of the N-terminal, ligand-binding region of integrin α-subunits into a β-propeller domain

  1997cited by this paper
• Mechanisms Initiating Platelet Thrombus Formation

  1997cited by this paper
• Thrombspondin Acts via Integrin-associated Protein to Activate the Platelet Integrin αIIbβ3 *

  1997cited by this paper
• Purification and Characterization of Gβγ-responsive Phosphoinositide 3-Kinases from Pig Platelet Cytosol*

  1997cited by this paper
• Negative Regulation of Mitogen-activated Protein Kinase Activation by Integrin αIIbβ3 in Platelets*

  1997cited by this paper
• ICAP-1, a Novel β1 Integrin Cytoplasmic Domain–associated Protein, Binds to a Conserved and Functionally Important NPXY Sequence Motif of β1 Integrin

  1997cited by this paper
• Platelet GPIIb/IIIa antagonists: the first anti-integrin receptor therapeutics.

  1997cited by this paper
• Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain.

  1997cited by this paper
• Role of PSGL-1 binding to selectins in leukocyte recruitment.

  1997cited by this paper
• Self-association of bound fibrinogen on platelet surfaces.

  1997cited by this paper
• The Significance of Subendothelial von Willebrand Factor

  1997cited by this paper
• Calpain Regulation of Cytoskeletal Signaling Complexes in Von Willebrand Factor-stimulated Platelets

  1997cited by this paper
• Calpain Cleavage of Focal Adhesion Proteins Regulates the Cytoskeletal Attachment of Integrin αIIbβ3 (Platelet Glycoprotein IIb/IIIa) and the Cellular Retraction of Fibrin Clots*

  1997cited by this paper
• Nitric oxide released from activated platelets inhibits platelet recruitment.

  1997cited by this paper
• Signalling through the lipid products of phosphoinositide-3-OH kinase

  1997cited by this paper
• Platelet alpha granule deficiency associated with decreased P-selectin and selective impairment of thrombin-induced activation in a new patient with gray platelet syndrome (alpha-storage pool deficiency).

  1997cited by this paper
• A Novel Association of Fc Receptor γ-Chain with Glycoprotein VI and Their Co-expression as a Collagen Receptor in Human Platelets*

  1997cited by this paper
• The tetraspanin superfamily: molecular facilitators

  1997cited by this paper
• Ras activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase C.

  1997cited by this paper
• The endothelial cell ecto-ADPase responsible for inhibition of platelet function is CD39.

  1997cited by this paper
• Overexpression of the Integrin-linked Kinase Promotes Anchorage-independent Cell Cycle Progression*

  1997cited by this paper
• Affinity Modulation of Platelet Integrin αIIbβ3 by β3-Endonexin, a Selective Binding Partner of the β3 Integrin Cytoplasmic Tail

  1997cited by this paper
• Perspectives series: cell adhesion in vascular biology. Integrin signaling in vascular biology.

  1997cited by this paper
• Molecular interactions in cell adhesion complexes.

  1997cited by this paper
• Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain.

  1997cited by this paper
• Platelet Receptors for Collagen

  1997cited by this paper
• Signaling through G Proteins in Platelets: to the Integrins and Beyond

  1997cited by this paper
• Complementation of dominant suppression implicates CD98 in integrin activation

  1997cited by this paper
• Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factor.

  1997cited by this paper
• Defective platelet activation in Gαq-deficient mice

  1997cited by this paper
• A conserved sequence motif in the integrin beta3 cytoplasmic domain is required for its specific interaction with beta3-endonexin.

  1997cited by this paper
• Signaling by Phosphoinositide-3,4,5-Trisphosphate Through Proteins Containing Pleckstrin and Sec7 Homology Domains

  1997cited by this paper
• PH domains--a universal membrane adapter.

  1997cited by this paper
• Perspectives series: cell adhesion in vascular biology. Role of PSGL-1 binding to selectins in leukocyte recruitment.

  1997influential reference
• Platelet signal transduction defect with Galpha subunit dysfunction and diminished Galphaq in a patient with abnormal platelet responses.

  1997cited by this paper
• Reassessment of protein tyrosine phosphorylation in thrombasthenic platelets: evidence that phosphorylation of cortactin and a 64-kD protein is dependent on thrombin activation and integrin alphaIIb beta3.

  1997cited by this paper
• Purification and characterization of Gbetagamma-responsive phosphoinositide 3-kinases from pig platelet cytosol.

  1997cited by this paper
• Platelet signal transduction defect with Gα subunit dysfunction and diminished Gαq in a patient with abnormal platelet responses

  1997cited by this paper
• Stimulation of Platelet Activation and Aggregation by a Carboxyl-terminal Peptide from Thrombospondin Binding to the Integrin-associated Protein Receptor*

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• Urokinase-Type Plasminogen Activator Receptors Associate with β1 and β3 Integrins of Fibrosarcoma Cells: Dependence on Extracellular Matrix Components

  1997cited by this paper
• Urokinase-type plasminogen activator receptors associate with beta1 and beta3 integrins of fibrosarcoma cells: dependence on extracellular matrix components.

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• A Conserved Sequence Motif in the Integrin β3 Cytoplasmic Domain Is Required for Its Specific Interaction with β3-Endonexin*

  1997cited by this paper
• Platelet Activation and Signal Transduction by Convulxin, a C-type Lectin from Crotalus durissus terrificus (Tropical Rattlesnake) Venom via the p62/GPVI Collagen Receptor*

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• Rapid Ca2+‐mediated activation of Rap1 in human platelets

  1997cited by this paper
• A collagen-like peptide stimulates tyrosine phosphorylation of syk and phospholipase C gamma2 in platelets independent of the integrin alpha2beta1.

  1997cited by this paper
• The platelet antigens CD9, CD42 and integrin alpha IIb beta IIIa can be topographically associated and transduce functionally similar signals.

  1997cited by this paper
• Role of MacMARCKS in Integrin-dependent Macrophage Spreading and Tyrosine Phosphorylation of Paxillin*

  1996cited by this paper
• Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis.

  1996cited by this paper
• Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor.

  1996influential reference
• Regulating integrin-mediated adhesion: one more function for PI 3-kinase?

  1996cited by this paper
• Paxillin association in vitro with integrin cytoplasmic domain peptides

  1996cited by this paper
• Breaking the Integrin Hinge

  1996cited by this paper
• Adhesion-growth factor interactions during differentiation: an integrated biological response.

  1996cited by this paper
• Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase

  1996cited by this paper
• Self-association of bound fibrinogen on platelet surfaces.

  1996cited by this paper
• D3 Phosphoinositides and Outside-in integrin Signaling by Glycoprotein IIb-IIIa Mediate Platelet Actin Assembly and Filopodial Extension Induced by Phorbol 12-Myristate 13-Acetate*

  1996cited by this paper
• Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins).

  1996cited by this paper
• Tyrosine Phosphorylation of the Fc Receptor γ-Chain in Collagen-stimulated Platelets*

  1996cited by this paper
• Analysis of GPIIb/IIIa receptor number by quantification of 7E3 binding to human platelets.

  1996cited by this paper
• Ligand binding to integrin alphaIIbbeta3 is dependent on a MIDAS-like domain in the beta3 subunit.

  1996cited by this paper
• Affinity modulation of the platelet integrin alpha IIb beta 3 by alpha-chymotrypsin: a possible role for Na+/Ca2+ exchanger.

  1996cited by this paper
• The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin.

  1996cited by this paper
• Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes.

  1996cited by this paper

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