Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals

Ikaros is essential for pre-BCR down-regulation, Igκ germline transcription, Ig light chain recombination, and pre-B cell differentiation, in part by antagonizing IL-7–dependent gene regulation.

• Publication year

  2013

• Venue

  Journal of Experimental Medicine

• Publication date

  2013-12-16

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/jem.20131735PMID 24297995PMCID 3865471
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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