Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Nature Medicine

• Publication date

  1995-07-01

• Fields of study

  Medicine, Chemistry, Psychology

• Identifiers
  DOI 10.1038/NM0795-654PMID 7585146
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• β-Endorphin-induced locomotor stimulation and reinforcement are associated with an increase in dopamine release in the nucleus accumbens

  2005cited by this paper
• SPECT imaging of dopamine and serotonin transporters with [123I]β-CIT. Binding kinetics in the human brain

  2005cited by this paper
• No structural mutation in the dopamine D2 receptor gene in alcoholism or schizophrenia. Analysis using denaturing gradient gel electrophoresis.

  1994cited by this paper
• Pet study of [11C] β‐CIT binding to monoamine transporters in the monkey and human brain

  1994cited by this paper
• The dosimetry of iodine-123 labelled 2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane.

  1994cited by this paper
• Striatal D2 dopamine receptor binding characteristics in vivo in patients with alcohol dependence

  1994cited by this paper
• Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson disease.

  1993cited by this paper
• DRD2 dopamine receptor genotype, linkage disequilibrium, and alcoholism in American Indians and other populations.

  1993cited by this paper
• Physical performance of the Siemens MultiSPECT 3 gamma camera

  1993cited by this paper
• Substance abuse vulnerability and D2 receptor genes

  1993cited by this paper
• Effects of D1 and D2 dopamine receptor agents on ethanol consumption in the high-alcohol-drinking (HAD) line of rats.

  1993cited by this paper
• Initial experience with single-photon emission tomography using iodine-123-labelled 2 beta-carbomethoxy-3 beta-(4-iodophenyl) tropane in human brain.

  1993cited by this paper
• The A1 allele at the D2 dopamine receptor gene and alcoholism. A reappraisal.

  1993cited by this paper
• Modulation of cocaine self-administration in the rat through D-3 dopamine receptors.

  1993cited by this paper
• Neurotransmitter regulation of dopamine neurons in the ventral tegmental area.

  1993cited by this paper
• D2 dopamine receptor genotype and cerebrospinal fluid homovanillic acid, 5‐hydroxyindoleacetic acid and 3‐methoxy‐4‐hydroxyphenylglycol in alcoholics in Finland and the United States

  1992cited by this paper
• Alcohol stimulates the release of dopamine and serotonin in the nucleus accumbens.

  1992cited by this paper
• Neurotransmitter transporters (plus): a promising new gene family.

  1992cited by this paper
• Genetic vulnerability to drug abuse. The D2 dopamine receptor Taq I B1 restriction fragment length polymorphism appears more frequently in polysubstance abusers.

  1992cited by this paper
• 5-HT2 receptor antagonists reverse amphetamine-induced slowing of dopaminergic neurons by interfering with stimulated dopamine synthesis.

  1992cited by this paper
• Drugs of abuse: anatomy, pharmacology and function of reward pathways.

  1992cited by this paper
• D2 dopamine receptor gene is associated but not linked with alcoholism.

  1991cited by this paper
• D2 dopamine receptor gene is associated but not linked with alcoholism.

  1991cited by this paper
• Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism.

  1991cited by this paper
• The dopamine D2 receptor locus as a modifying gene in neuropsychiatric disorders.

  1991cited by this paper
• Repeated treatment with imipramine potentiates cocaine-induced dopamine release and motor stimulation.

  1991cited by this paper
• No linkage between D2 dopamine receptor gene region and schizophrenia.

  1991cited by this paper
• No association between an allele at the D2 dopamine receptor gene (DRD2) and alcoholism.

  1991cited by this paper
• Allelic association of human dopamine D2 receptor gene in alcoholism.

  1990cited by this paper
• Neurogenetic adaptive mechanisms in alcoholism.

  1987cited by this paper
• Aggression in mice associated with changes in the monoamine-metabolism of the brain

  1969cited by this paper

• Molecular Imaging Studies of Alcohol Use Disorder.

  2023cites this paper
• Dopamine and Alcohol: A Review of in vivo PET and SPECT Studies

  2023cites this paper
• Dopamine transporter availability in alcohol and opioid dependent subjects - a 99mTc-TRODAT-1SPECT imaging and genetic association study.

  2020cites this paper
• Addictions NeuroImaging Assessment (ANIA): towards an integrative framework for alcohol use disorder.

  2020cites this paper
• Positron Emission Tomography of the

  2020cites this paper
• Abnormalities of Neurotransmission in Drug Addiction

  2020cites this paper
• Dopamine and opioid systems adaptation in alcoholism revisited: Convergent evidence from positron emission tomography and postmortem studies.

  2019cites this paper
• Alcohol and Violence in Psychopathy and Antisocial Personality Disorder: Neural Mechanisms

  2019cites this paper
• Neurochemical Imaging in Addiction

  2019cites this paper
• AZI23’UTR Is a New SLC6A3 Downregulator Associated with an Epistatic Protection Against Substance Use Disorders

  2018cites this paper
• Cross-Species Alterations in Synaptic Dopamine Regulation After Chronic Alcohol Exposure.

  2018cites this paper
• Effects of sedative drug use on the dopamine system: a systematic review and meta-analysis of in vivo neuroimaging studies

  2018cites this paper
• Psychopathy Moderates the Relationship between Orbitofrontal and Striatal Alterations and Violence: The Investigation of Individuals Accused of Homicide

  2017cites this paper
• Deep Transcranial Magnetic Stimulation of the Dorsolateral Prefrontal Cortex in Alcohol Use Disorder Patients: Effects on Dopamine Transporter Availability and Alcohol Intake.

  2017cites this paper
• Neurochemical and metabolic effects of acute and chronic alcohol in the human brain: Studies with positron emission tomography.

  2017cites this paper
• Impulsive-antisocial dimension of psychopathy linked to enlargement and abnormal functional connectivity of the striatum.

  2017cites this paper
• Perspectives on fronto‐fugal circuitry from human imaging of alcohol use disorders

  2017cites this paper
• Reward Dependence and Reward Deficiency

  2016cites this paper
• How Imaging Glutamate, GABA, and Dopamine Can Inform the Clinical Treatment of Alcohol Dependence and Withdrawal

  2016cites this paper
• Neuropathology of Gene Expression during Alcohol Withdrawal

  2016cites this paper
• How Imaging Glutamate, γ-Aminobutyric Acid, and Dopamine Can Inform the Clinical Treatment of Alcohol Dependence and Withdrawal.

  2015cites this paper
• Mesocorticolimbic dopamine functioning in primary psychopathy: A source of within-group heterogeneity.

  2015cites this paper
• DAT1 methylation changes in alcohol-dependent individuals vs. controls.

  2015cites this paper
• The Relationship of Alcohol Dependence to Monoamine Oxidase A

  2015cites this paper
• Neural Mechanisms Associated with Stress‐Induced Drug Craving

  2015cites this paper
• Testosterone and Addiction

  2015cites this paper
• Possible role of a dysregulation of the endogenous opioid system in antisocial personality disorder

  2015cites this paper
• Impulsive alcohol-related risk-behavior and emotional dysregulation among individuals with a serotonin 2B receptor stop codon

  2015cites this paper
• Physiological correlates of psychopathy, antisocial personality disorder, habitual aggression, and violence.

  2014cites this paper
• Molecular imaging in alcohol dependence.

  2014cites this paper
• Epigenetic alteration of the dopamine transporter gene in alcohol‐dependent patients is associated with age

  2014cites this paper
• Hypothesizing dopaminergic genetic antecedents in schizophrenia and substance seeking behavior.

  2014cites this paper
• Electrophysiology and Psychophysiology in Psychiatry and Psychopharmacology

  2014cites this paper
• Imaging studies on dopamine transporter and depression: a review of literature and suggestions for future research.

  2014cites this paper
• Increased Turnover of Dopamine in Caudate Nucleus of Detoxified Alcoholic Patients

  2013cites this paper
• Differences in Behavior and Activity Associated with a Poly(A) Expansion in the Dopamine Transporter in Belgian Malinois

  2013cites this paper
• Characterization of a dopamine transporter polymorphism and behavior in Belgian Malinois

  2013cites this paper
• Neurochemical Imaging of Addictive Disorders

  2012cites this paper
• Neuroimaging in Psychopathy and Antisocial Personality Disorder: Functional Significance and a Neurodevelopmental Hypothesis

  2012cites this paper
• The potential role of the striatum in antisocial behavior and psychopathy.

  2012cites this paper
• Consensus Report of the APA Work Group on Neuroimaging Markers of Psychiatric Disorders RESOURCE DOCUMENT

  2012cites this paper
• Nuclear Medicine in Finland

  2012cites this paper
• Involvement of nucleus accumbens dopamine D1 receptors in ethanol drinking, ethanol-induced conditioned place preference, and ethanol-induced psychomotor sensitization in mice

  2012cites this paper
• Neurogenetics and Nutrigenomics of Reward Deficiency Syndrome

  2011cites this paper
• UNDERSTANDING THE HIGH MIND: HUMANS ARE STILL EVOLVING GENETICALLY

  2011cites this paper
• The association between the SLC6A3 VNTR 9-repeat allele and alcoholism-a meta-analysis.

  2011cites this paper
• Extrastriatal dopamine D2/3 receptors in schizophrenia

  2011cites this paper
• Structural and functional neuroimaging studies of the suicidal brain.

  2011cites this paper
• Alcohol and the human brain: a systematic review of different neuroimaging methods.

  2011cites this paper
• Dopamine dynamics associated with, and resulting from, schedule-induced alcohol self-administration: analyses in dopamine transporter knockout mice.

  2011cites this paper
• Low novelty seeking and high self directedness scores in alcohol-dependent patients without comorbid psychiatric disorders homozygous for the A10 allele of the dopamine transporter gene.

  2010cites this paper
• Increased volume of the striatum in psychopathic individuals.

  2010cites this paper
• Low novelty seeking and high self directedness scores in alcohol-dependent patients without comorbid psychiatric disorders homozygous for the A10 allele of the dopamine transporter gene

  2010cites this paper
• Are genetic variants of COMT associated with addiction?

  2010cites this paper
• In Vivo Imaging of Dopamine Receptors

  2010cites this paper
• Imaging receptor changes in human drug abusers.

  2010influential citation
• Endogenous cannabinoids in post-mortem brains of Cloninger type 1 and 2 alcoholics.

  2010cites this paper
• Association between harmful alcohol consumption behavior and dopamine transporter (DAT1) gene polymorphisms in a male Finnish population

  2009cites this paper
• Neurogenetics of Dopaminergic Receptor Supersensitivity in Activation of Brain Reward Circuitry and Relapse: Proposing “Deprivation-Amplification Relapse Therapy” (DART)

  2009cites this paper
• DOPAMINE AND SEROTONIN TRANSPORTER AVAILABILITY DURING ACUTE ALCOHOL WITHDRAWAL: EFFECTS OF COMORBID TOBACCO SMOKING

  2009cites this paper
• Typologies of Alcohol Dependence. From Jellinek to Genetics and Beyond

  2009cites this paper
• Polymorphisms in the dopamine transporter gene (SLC6A3/DAT1) and alcohol dependence in humans: a systematic review.

  2009cites this paper
• Role of the dopamine transporter in the action of psychostimulants, nicotine, and other drugs of abuse.

  2008cites this paper
• Cortical dopamine D(1) receptors in type 1 and type 2 alcoholics measured with human whole hemisphere autoradiography.

  2008cites this paper
• Psychophysiological correlates of aggression and violence: an integrative review

  2008cites this paper
• Appetitive Motivation Predicts the Neural Response to Facial Signals of Aggression

  2008cites this paper
• The Scientific Building Blocks of PeaceBuilders Nine Key Principles of the Science of PeaceBuilding

  2008cites this paper
• Ethanol potentiates dopamine uptake and increases cell surface distribution of dopamine transporters expressed in SK-N-SH and HEK-293 cells.

  2008influential citation
• Pharmacogenomic strategy for individualizing antidepressant therapy

  2008cites this paper
• Role of Serotonin and Dopamine System Interactions in the Neurobiology of Impulsive Aggression and its Comorbidity with other Clinical Disorders.

  2008cites this paper
• Striatal dopaminergic terminals in type 1 and type 2 alcoholics measured with [3H]dihydrotetrabenazine and human whole hemisphere autoradiography.

  2008cites this paper
• Approach to the genetics of alcoholism: a review based on pathophysiology.

  2008cites this paper
• Imaging the neurochemistry of alcohol and substance abuse.

  2007cites this paper
• Neurochemistry and Molecular Neurobiology of Aggressive Behavior

  2007cites this paper
• D2 dopamine receptor gene haplotypes and their influence on alcohol and tobacco consumption magnitude in alcohol-dependent individuals.

  2007cites this paper
• Chapter 9 – Neuroimaging

  2007cites this paper
• Dopamine Genes and Pathological Gambling in Discordant Sib-Pairs

  2007cites this paper
• Applications of Clinical Dopamine Imaging.

  2007cites this paper
• Epidemiological Study on Factors Associated with Severe Violent Offending

  2007cites this paper
• Investigating the Dopaminergic Synapse In Vivo. I. Molecular Imaging Studies in Humans

  2007cites this paper
• Amygdala serotonin transporters in alcoholics measured by whole hemisphere autoradiography

  2007cites this paper
• Synaptamine (SG8839),TM An Amino-Acid Enkephalinase Inhibition Nutraceutical Improves Recovery of Alcoholics, A Subtype of Reward Deficiency Syndrome (RDS)

  2007cites this paper
• Preliminary association of both the Dopamine D2 Receptor (DRD2) (Taq1 A1 Allele) and the Dopamine Transporter (DAT1) (480 bp Allele) genes with pathological aggressive behavior, a clinical subtype of Reward Deficiency Syndrome (RDS) in adolescents

  2007cites this paper
• Visualization of the cortical dopamine transporter in type 1 and 2 alcoholics with human whole hemisphere autoradiography.

  2006cites this paper
• Partly dissociable neural substrates for recognizing basic emotions: a critical review.

  2006cites this paper
• Evidence for Genetic Predispositions for Criminogenic Behavior

  2006cites this paper
• A genetic association study of dopamine metabolism‐related genes and chronic headache with drug abuse

  2006cites this paper
• Nucleus accumbens serotonin transporters in alcoholics measured by whole-hemisphere autoradiography.

  2006cites this paper
• Lower serotonin transporter binding in caudate in alcoholics

  2006cites this paper
• No role of the dopamine transporter in acute ethanol effects on striatal dopamine dynamics

  2006cites this paper
• Biological Influences on Criminal Behavior

  2006cites this paper
• Applications of clinical dopamine imaging.

  2006cites this paper
• Deep serotonergic and dopaminergic structures in fetal alcoholic syndrome: a study with nor-beta-CIT-single-photon emission computed tomography and magnetic resonance imaging volumetry.

  2005cites this paper
• Striatal dopamine transporter availability with [123I]β-CIT SPECT is unrelated to gender or menstrual cycle

  2005cites this paper
• Association of the dopamine transporter gene with alcoholism.

  2005influential citation
• Are dopaminergic genes involved in a predisposition to pathological aggression? Hypothesizing the importance of "super normal controls" in psychiatricgenetic research of complex behavioral disorders.

  2005cites this paper
• Neuroreceptor imaging in psychiatry: theory and applications.

  2005cites this paper
• Chapter IX Human forebrain dopamine systems: Characterization of the normal brain and in relation to psychiatric disorders

  2005cites this paper
• 123I-β-CIT binding and recovery from depression

  2004cites this paper
• Pharmacogenetic insights to monoaminergic dysfunction in alcohol dependence

  2004influential citation