Retromer Is Required for Apoptotic Cell Clearance by Phagocytic Receptor Recycling

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Science

• Publication date

  2010-03-05

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1126/science.1184840PMID 20133524
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulation of endosomal clathrin and retromer‐mediated endosome to Golgi retrograde transport by the J‐domain protein RME‐8

  2009cited by this paper
• The Retromer Coat Complex Coordinates Endosomal Sorting and Dynein-Mediated Transport, with Carrier Recognition by the trans-Golgi Network

  2009cited by this paper
• The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network.

  2008cited by this paper
• C. elegans AP-2 and retromer control Wnt signaling by regulating mig-14/Wntless.

  2008cited by this paper
• Wnt signaling requires retromer-dependent recycling of MIG-14/Wntless in Wnt-producing cells.

  2008cited by this paper
• Endosomal sorting and signalling: an emerging role for sorting nexins

  2008cited by this paper
• Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex

  2008cited by this paper
• Wingless secretion promotes and requires retromer-dependent cycling of Wntless

  2008cited by this paper
• The Structure and Function of the Retromer Protein Complex

  2008cited by this paper
• Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling

  2007cited by this paper
• Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans

  2006cited by this paper
• C. elegans GLA-3 is a novel component of the MAP kinase MPK-1 signaling pathway required for germ cell survival.

  2006cited by this paper
• C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells.

  2006cited by this paper
• Wnt Gradient Formation Requires Retromer Function in Wnt-Producing Cells

  2006cited by this paper
• Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor

  2004cited by this paper
• The engulfment process of programmed cell death in caenorhabditis elegans.

  2004cited by this paper
• The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor

  2004cited by this paper
• Genome-wide RNAi screening in Caenorhabditis elegans.

  2003cited by this paper
• CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans.

  2001cited by this paper
• Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

  1999cited by this paper
• A Membrane Coat Complex Essential for Endosome-to-Golgi Retrograde Transport in Yeast

  1998cited by this paper

• Plasma membrane-to-lysosome FGR signaling regulates endocytosis-associated lysosome homeostasis.

  2026cites this paper
• DHHC-1-dependent modulation of CED-1 protein stability regulates apoptotic cell clearance in C. elegans.

  2025cites this paper
• Proteomics Insights Into Lysosome Biogenesis and Maturation

  2025cites this paper
• Integrating transcriptomics, network analysis, and single-cell RNA sequencing to identify and validate key target genes of gynostemma in the treatment of non-alcoholic fatty liver disease.

  2025cites this paper
• Rising Star: Lysosomes as dead cell buriers and key guardians of organismal homeostasis.

  2025cites this paper
• Exploring lysosomal biology: current approaches and methods

  2024cites this paper
• CED-6/GULP and components of the clathrin-mediated endocytosis machinery act redundantly to correctly display CED-1 on the cell membrane in Caenorhabditis elegans

  2024cites this paper
• Efferocytosis by macrophages in physiological and pathological conditions: regulatory pathways and molecular mechanisms

  2024cites this paper
• A PI(3,5)P2 reporter reveals PIKfyve activity and dynamics on macropinosomes and phagosomes

  2023cites this paper
• Beclin 1 regulates astrocyte phagocytosis and phagosomal recruitment of retromer.

  2023cites this paper
• Hereditary spastic paraplegia: Novel insights into the pathogenesis and management

  2023influential citation
• The resolution of phagosomes

  2023cites this paper
• Diversity of retromer-mediated vesicular trafficking pathways in plants

  2023cites this paper
• Visualizing Phagocytic Cargo In Vivo from Engulfment to Resolution in Caenorhabditis elegans.

  2023cites this paper
• Soluble Trem2 is a negative regulator of erythrophagocytosis after intracerebral hemorrhage in a CD36 receptor recycling manner

  2022cites this paper
• trim-21 promotes proteasomal degradation of CED-1 for apoptotic cell clearance in C. elegans

  2022cites this paper
• Microglial efferocytosis: Diving into the Alzheimer's disease gene pool.

  2022cites this paper
• The Ubiquitin-Proteasome System in Apoptosis and Apoptotic Cell Clearance

  2022cites this paper
• Phagosome maturation in macrophages: Eat, digest, adapt, and repeat.

  2021cites this paper
• The retromer complex regulates C. elegans development and mammalian ciliogenesis

  2021cites this paper
• Toward Understanding the Molecular Role of SNX27/Retromer in Human Health and Disease

  2021cites this paper
• Lysosome biogenesis: Regulation and functions

  2021cites this paper
• Examining the Underappreciated Role of S-Acylated Proteins as Critical Regulators of Phagocytosis and Phagosome Maturation in Macrophages

  2021influential citation
• SNX-PXA-RGS-PXC Subfamily of SNXs in the Regulation of Receptor-Mediated Signaling and Membrane Trafficking

  2021cites this paper
• The developmental and physiological roles of phagocytosis in Caenorhabditis elegans.

  2021cites this paper
• Mechanism of cargo recognition by retromer-linked SNX-BAR proteins

  2020cites this paper
• Defective apoptotic cell clearance activates innate immune response to protect Caenorhabditis elegans against pathogenic bacteria

  2020influential citation
• Rab GTPases in the differential processing of phagocytosed pathogens versus efferocytosed apoptotic cells.

  2020cites this paper
• Loss of the Major Phosphatidylserine or Phosphatidylethanolamine Flippases Differentially Affect Phagocytosis

  2020influential citation
• Defective arginine metabolism impairs mitochondrial homeostasis in Caenorhabditiselegans.

  2020cites this paper
• Coupling of terminal differentiation deficit with neurodegenerative pathology in Vps35-deficient pyramidal neurons

  2020cites this paper
• Autophagy in C. elegans development.

  2019cites this paper
• The amino acid transporter SLC-36.1 cooperates with PtdIns3P 5-kinase to control phagocytic lysosome reformation

  2019cites this paper
• The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling.

  2018cites this paper
• C. elegans Blastomeres Clear the Corpse of the Second Polar Body by LC3-Associated Phagocytosis.

  2018cites this paper
• Retromer associated sorting nexins SNX1, SNX4, and SNX27 and the trafficking and basolateral membrane population of the intermediate conductance calcium activated potassium channel (KCa3.1) in polarised epithelial cells

  2018cites this paper
• Characterization Of A Novel Vps26c-Retromer Complex And Its Interaction With An Endosomal Trafficking Pathway Regulated By The Snare Vti13 In Controlling Polarized Growth And Cell Wall Organization In Arabidopsis Thaliana

  2018cites this paper
• Ubiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation

  2018cites this paper
• The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking

  2018cites this paper
• Extracellular vesicle budding is inhibited by redundant regulators of TAT-5 flippase localization and phospholipid asymmetry

  2018cites this paper
• To degrade or not to degrade: mechanisms and significance of endocytic recycling

  2018cites this paper
• The phosphorylation of sorting nexin 5 at serine 226 regulates retrograde transport and macropinocytosis

  2018cites this paper
• The lysine catabolite saccharopine impairs development by disrupting mitochondrial homeostasis

  2018cites this paper
• Endosomal Retrieval of Cargo: Retromer Is Not Alone.

  2018cites this paper
• Retromer's Role in Endosomal Trafficking and Impaired Function in Neurodegenerative Diseases.

  2017cites this paper
• JCB_201702137 3677..3694

  2017cites this paper
• The Recycling GTPase, RAB-10, Regulates Autophagy Flux in Caenorhabditis elegans

  2017influential citation
• COMMD10 Regulates Protein Trafficking

  2017cites this paper
• Updated Insight into the Physiological and Pathological Roles of the Retromer Complex

  2017cites this paper
• Dissecting Phagocytic Removal of Apoptotic Cells in Caenorhabditis elegans.

  2017cites this paper
• Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport

  2017cites this paper
• Ubiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation

  2017cites this paper
• Retromer in Polarized Protein Transport.

  2016cites this paper
• Role of the Retromer Complex in Neurodegenerative Diseases

  2016cites this paper
• Programmed Cell Death During Caenorhabditis elegans Development

  2016cites this paper
• Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis

  2016cites this paper
• Programmed cell death and clearance of cell corpses in Caenorhabditis elegans

  2016cites this paper
• Retromer in Osteoblasts Interacts With Protein Phosphatase 1 Regulator Subunit 14C, Terminates Parathyroid Hormone's Signaling, and Promotes Its Catabolic Response

  2016cites this paper
• WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptors

  2016cites this paper
• Retromer-Mediated Protein Sorting and Vesicular Trafficking.

  2016cites this paper
• Resolving the homology-function relationship through comparative genomics of membrane-trafficking machinery and parasite cell biology.

  2016cites this paper
• N-TERMINALLY ELONGATED SpliInx2 AND SpliInx3 REDUCE BACULOVIRUS-TRIGGERED APOPTOSIS VIA HEMICHANNEL CLOSURE.

  2016cites this paper
• Dictyostelium EHD associates with Dynamin and participates in phagosome maturation

  2016cites this paper
• Retromer Endosome Exit Domains Serve Multiple Trafficking Destinations and Regulate Local G Protein Activation by GPCRs.

  2016cites this paper
• C. elegans midbodies are released, phagocytosed and undergo LC3-dependent degradation independent of macroautophagy

  2016cites this paper
• Depletion of vacuolar protein sorting-associated protein 35 is associated with increased lysosomal degradation of aquaporin-2.

  2016cites this paper
• The proneurotrophin receptor sortilin is required for Mycobacterium tuberculosis control by macrophages

  2016cites this paper
• Synaptotagmin 1 directs repetitive release by coupling vesicle exocytosis to the Rab3 cycle

  2015influential citation
• High-Throughput All-Optical Analysis of Synaptic Transmission and Synaptic Vesicle Recycling in Caenorhabditis elegans

  2015cites this paper
• Retromer Contributes to Immunity-Associated Cell Death in Arabidopsis

  2015cites this paper
• A defect in the retromer accessory protein, SNX27, manifests by infantile myoclonic epilepsy and neurodegeneration

  2015cites this paper
• Formation of Tubulovesicular Carriers from Endosomes and Their Fusion to the trans-Golgi Network.

  2015cites this paper
• The GTP- and Phospholipid-Binding Protein TTD14 Regulates Trafficking of the TRPL Ion Channel in Drosophila Photoreceptor Cells

  2015cites this paper
• Antimicrobial Mechanisms of Macrophages and the Immune Evasion Strategies of Staphylococcus aureus

  2015cites this paper
• VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease

  2015cites this paper
• Biogenesis of endosome-derived transport carriers

  2015cites this paper
• Retromer and sorting nexins in endosomal sorting.

  2015cites this paper
• Identification of parkin interactions: implications for Parkinson’s disease

  2015cites this paper
• Exocytosis and Endocytosis

  2014cites this paper
• Retromer: a master conductor of endosome sorting.

  2014influential citation
• Subcellular localisation of retromer in post‐endocytic pathways of polarised Madin–Darby canine kidney cells

  2014cites this paper
• TREM-2 expression and regulation in inflammation and ischaemia

  2014cites this paper
• C. elegans as a model for membrane traffic.

  2014cites this paper
• TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation

  2014cites this paper
• Application of RNAi technology and fluorescent protein markers to study membrane traffic in C. elegans.

  2014cites this paper
• The lysosomal cathepsin protease CPL-1 plays a leading role in phagosomal degradation of apoptotic cells in Caenorhabditis elegans

  2014cites this paper
• Retromer Promotes Immune Quiescence by Suppressing Spätzle‐Toll Pathway in Drosophila

  2014cites this paper
• Sorting Through the Roles of Beclin 1 in Microglia and Neurodegeneration

  2014cites this paper
• mTOR regulates phagosome and entotic vacuole fission

  2013cites this paper
• Clathrin and AP2 Are Required for Phagocytic Receptor-Mediated Apoptotic Cell Clearance in Caenorhabditis elegans

  2013cites this paper
• Autophagy genes coordinate with the class II PI/PtdIns 3-kinase PIKI-1 to regulate apoptotic cell clearance in C. elegans

  2013cites this paper
• The VPS35 gene and Parkinson's disease

  2013cites this paper
• Retromer maintains basolateral distribution of the type II TGF-β receptor via the recycling endosome

  2013cites this paper
• Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling

  2013cites this paper
• Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease.

  2013cites this paper
• Role of phospholipids in endocytosis, phagocytosis, and macropinocytosis.

  2013cites this paper
• The giardial VPS35 retromer subunit is necessary for multimeric complex assembly and interaction with the vacuolar protein sorting receptor.

  2013cites this paper
• VPS 35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE 1

  2012cites this paper
• Membrane trafficking and phagosome maturation during the clearance of apoptotic cells.

  2012influential citation
• The Role of Retromer in Regulating the Apical-Basal Polarity and the Immune Response during Drosophila Development

  2012influential citation