Peroxisomal matrix protein receptor ubiquitination and recycling.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Biochimica et Biophysica Acta

• Publication date

  2006-12-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.BBAMCR.2006.08.046PMID 17028012
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The N-terminal half of the peroxisomal cycling receptor Pex5p is a natively unfolded domain.

  2006cited by this paper
• The ESCRT complexes: structure and mechanism of a membrane-trafficking network.

  2006cited by this paper
• Identification and characterization of three peroxins--PEX6, PEX10 and PEX12--involved in glycosome biogenesis in Trypanosoma brucei.

  2006cited by this paper
• Dynamics of the peroxisomal import cycle of PpPex20p

  2006influential reference
• The evolutionary origin of peroxisomes: an ER-peroxisome connection.

  2006cited by this paper
• Origin and evolution of the peroxisomal proteome

  2006cited by this paper
• Differential Regulation of Rad18 through Rad6-dependent Mono- and Polyubiquitination*

  2005cited by this paper
• Obstruction of polyubiquitination affects PTS1 peroxisomal matrix protein import.

  2005cited by this paper
• Ubiquitin-binding domains

  2005cited by this paper
• Hansenula polymorpha Pex20p is an oligomer that binds the peroxisomal targeting signal 2 (PTS2)

  2005cited by this paper
• Dynamin‐related proteins and Pex11 proteins in peroxisome division and proliferation

  2005cited by this paper
• Endoplasmic reticulum-associated degradation.

  2005cited by this paper
• Alternative splicing suggests extended function of PEX26 in peroxisome biogenesis.

  2005cited by this paper
• Requirement for Microtubules and Dynein Motors in the Earliest Stages of Peroxisome Biogenesis

  2005cited by this paper
• A genomic and functional inventory of deubiquitinating enzymes.

  2005cited by this paper
• The Saccharomyces cerevisiae Peroxisomal Import Receptor Pex5p Is Monoubiquitinated in Wild Type Cells*

  2005cited by this paper
• Ubiquitination of the Peroxisomal Targeting Signal Type 1 Receptor, Pex5p, Suggests the Presence of a Quality Control Mechanism during Peroxisomal Matrix Protein Import*

  2005cited by this paper
• Identification and Functional Characterization of Arabidopsis PEROXIN4 and the Interacting Protein PEROXIN22[W]

  2005cited by this paper
• Golgi reassembly after mitosis: the AAA family meets the ubiquitin family.

  2005cited by this paper
• AAA+ proteins: have engine, will work

  2005cited by this paper
• ERAD: the long road to destruction

  2005cited by this paper
• Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol

  2005cited by this paper
• Shuttling Mechanism of Peroxisome Targeting Signal Type 1 Receptor Pex5: ATP-Independent Import and ATP-Dependent Export

  2005influential reference
• A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting.

  2005cited by this paper
• Structure of the N-terminal domain of PEX1 AAA-ATPase. Characterization of a putative adaptor-binding domain.

  2005cited by this paper
• The Arabidopsis PEX12 Gene Is Required for Peroxisome Biogenesis and Is Essential for Development1[w]

  2005cited by this paper
• Delivery of ubiquitinated substrates to protein-unfolding machines

  2005cited by this paper
• Kinesin and Dynein Move a Peroxisome in Vivo: A Tug-of-War or Coordinated Movement?

  2005cited by this paper
• Peroxisomal matrix protein import: the transient pore model

  2005cited by this paper
• E3 ubiquitin ligases.

  2005cited by this paper
• Golgi reassembly after mitosis: the AAA family meets the ubiquitin family.

  2005cited by this paper
• Structural and functional analysis of the interaction of the AAA‐peroxins Pex1p and Pex6p

  2004cited by this paper
• An Arabidopsis indole-3-butyric acid-response mutant defective in PEROXIN6, an apparent ATPase implicated in peroxisomal function.

  2004cited by this paper
• Functional Similarity between the Peroxisomal PTS2 Receptor Binding Protein Pex18p and the N-Terminal Half of the PTS1 Receptor Pex5p

  2004cited by this paper
• Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane

  2004cited by this paper
• The N Terminus of the Peroxisomal Cycling Receptor, Pex5p, Is Required for Redirecting the Peroxisome-associated Peroxin Back to the Cytosol*

  2004cited by this paper
• An unstructured initiation site is required for efficient proteasome-mediated degradation

  2004cited by this paper
• Binding of Cdc48p to a ubiquitin‐related UBX domain from novel yeast proteins involved in intracellular proteolysis and sporulation

  2004cited by this paper
• Structure of the N-terminal Domain of PEX1 AAA-ATPase

  2004cited by this paper
• Pex7p translocates in and out of peroxisomes in Saccharomyces cerevisiae

  2004cited by this paper
• Ubiquitination of the peroxisomal import receptor Pex5p.

  2004cited by this paper
• Evolutionary history and higher order classification of AAA+ ATPases.

  2004influential reference
• VCIP135 acts as a deubiquitinating enzyme during p97–p47-mediated reassembly of mitotic Golgi fragments

  2004cited by this paper
• The Energetics of Pex5p-mediated Peroxisomal Protein Import*

  2003influential reference
• Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome

  2003cited by this paper
• The pathogenic peroxin Pex26p recruits the Pex1p–Pex6p AAA ATPase complexes to peroxisomes

  2003cited by this paper
• AthPEX10, a nuclear gene essential for peroxisome and storage organelle formation during Arabidopsis embryogenesis

  2003cited by this paper
• Pex 15 p of Saccharomyces cerevisiae provides the molecular basis for recruitment of the AAA peroxin Pex 6 p to peroxisomal membranes

  2003cited by this paper
• Pex15p of Saccharomyces cerevisiae provides a molecular basis for recruitment of the AAA peroxin Pex6p to peroxisomal membranes.

  2003cited by this paper
• The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state.

  2003cited by this paper
• Pex7p and Pex20p of Neurospora crassa function together in PTS2-dependent protein import into peroxisomes.

  2003cited by this paper
• Peroxisome biogenesis.

  2003cited by this paper
• Pex8p: an intraperoxisomal organizer of the peroxisomal import machinery.

  2003cited by this paper
• Insertion of Pex5p into the Peroxisomal Membrane Is Cargo Protein-dependent*

  2003cited by this paper
• Peroxisome biogenesis: advances and conundrums.

  2003cited by this paper
• Mono- Versus Polyubiquitination: Differential Control of p53 Fate by Mdm2

  2003cited by this paper
• Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins.

  2003cited by this paper
• Peroxisomal-protein import: is it really that complex?

  2002cited by this paper
• A specific protein substrate for a deubiquitinating enzyme: Liquid facets is the substrate of Fat facets.

  2002cited by this paper
• Role of the ubiquitin‐selective CDC48UFD1/NPL4 chaperone (segregase) in ERAD of OLE1 and other substrates

  2002cited by this paper
• VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo

  2002cited by this paper
• ER-associated degradation in protein quality control and cellular regulation.

  2002cited by this paper
• Cdc48 can distinguish between native and non‐native proteins in the absence of cofactors

  2002cited by this paper
• Yarrowia lipolytica Pex20p, Saccharomyces cerevisiae Pex18p/Pex21p and mammalian Pex5pL fulfil a common function in the early steps of the peroxisomal PTS2 import pathway

  2001cited by this paper
• Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly

  2001cited by this paper
• Dynamics of peroxisome assembly and function.

  2001cited by this paper
• The life cycle of the peroxisome

  2001cited by this paper
• Characterization of the Mammalian Peroxisomal Import Machinery

  2001cited by this paper
• Ubiquitin and proteasomes: Themes and variations on ubiquitylation

  2001cited by this paper
• The human peroxisomal targeting signal receptor, Pex5p, is translocated into the peroxisomal matrix and recycled to the cytosol.

  2001cited by this paper
• Pex18p Is Constitutively Degraded during Peroxisome Biogenesis*

  2001influential reference
• N-ethylmaleimide sensitive factor (NSF) structure and function.

  2001cited by this paper
• Pex12p of Saccharomyces cerevisiae is a component of a multi-protein complex essential for peroxisomal matrix protein import.

  2001cited by this paper
• AAA+ superfamily ATPases: common structure–diverse function

  2001cited by this paper
• Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism.

  2001cited by this paper
• The structures of HsIU and the ATP-dependent protease HsIU-HsIV.

  2000cited by this paper
• Molecular Anatomy of the Peroxin Pex12p

  2000cited by this paper
• Analysis of the Deubiquitinating Enzymes of the Yeast Saccharomyces cerevisiae

  2000cited by this paper
• The Peroxisome Biogenesis Factors Pex4p, Pex22p, Pex1p, and Pex6p Act in the Terminal Steps of Peroxisomal Matrix Protein Import

  2000cited by this paper
• Characterization of Peroxisomal Pex5p from Rat Liver

  2000cited by this paper
• Crystal and solution structures of an HslUV protease-chaperone complex.

  2000cited by this paper
• Rad6-dependent ubiquitination of histone H2B in yeast.

  2000cited by this paper
• Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila.

  2000cited by this paper
• Pex22p of Pichia pastoris, Essential for Peroxisomal Matrix Protein Import, Anchors the Ubiquitin-Conjugating Enzyme, Pex4p, on the Peroxisomal Membrane

  1999cited by this paper
• AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes.

  1999cited by this paper
• Pex 22 p of Pichia pastoris , Essential for Peroxisomal Matrix Protein Import , Anchors the Ubiquitin-conjugating Enzyme , Pex 4 p , on the Peroxisomal Membrane

  1999cited by this paper
• Hansenula polymorpha Pex1p and Pex6p are peroxisome‐associated AAA proteins that functionally and physically interact

  1999cited by this paper
• Pex12 Interacts with Pex5 and Pex10 and Acts Downstream of Receptor Docking in Peroxisomal Matrix Protein Import

  1999cited by this paper
• The Cytosolic DnaJ-like Protein Djp1p Is Involved Specifically in Peroxisomal Protein Import

  1998cited by this paper
• Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins.

  1998cited by this paper
• A cytoplasmic AAA family peroxin, Pex1p, interacts with Pex6p.

  1998cited by this paper
• Two AAA Family Peroxins, PpPex1p and PpPex6p, Interact with Each Other in an ATP-Dependent Manner and Are Associated with Different Subcellular Membranous Structures Distinct from Peroxisomes

  1998cited by this paper
• Identification of PEX10, the gene defective in complementation group 7 of the peroxisome-biogenesis disorders.

  1998cited by this paper
• Pex20p of the Yeast Yarrowia lipolytica Is Required for the Oligomerization of Thiolase in the Cytosol and for Its Targeting to the Peroxisome

  1998cited by this paper
• Nucleotide triphosphates are required for the transport of glycolate oxidase into peroxisomes.

  1998cited by this paper
• The ubiquitin‐conjugating enzyme Pex4p of Hansenula polymorpha is required for efficient functioning of the PTS1 import machinery

  1998cited by this paper
• Mutations in PEX1 are the most common cause of peroxisome biogenesis disorders

  1997cited by this paper
• Multiple PEX genes are required for proper subcellular distribution and stability of Pex5p, the PTS1 receptor: evidence that PTS1 protein import is mediated by a cycling receptor

  1996cited by this paper
• The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor.

  1996cited by this paper
• Formation of the peroxisome lumen is abolished by loss of Pichia pastoris Pas7p, a zinc-binding integral membrane protein of the peroxisome

  1995cited by this paper

• Pex6 and ubiquitination regulate topological remodeling of the peroxisomal membrane protein Pex14.

  2026cites this paper
• The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity

  2025cites this paper
• Peroxisome protein import deficiency causes heart failure in mouse and human

  2025cites this paper
• RNF20/RNF40 supports the aggressive behavior in cervical cancer by regulating a peroxisome-based anti-ferroptotic mechanism

  2025cites this paper
• PEX5-mediated modulation of apoptotic pathways in response to Newcastle disease virus infection1

  2024cites this paper
• The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging

  2023cites this paper
• An adaptive stress response that confers cellular resilience to decreased ubiquitination

  2023cites this paper
• Peroxisomal Stress Response and Inter-Organelle Communication in Cellular Homeostasis and Aging

  2022cites this paper
• The peroxisomal disorder spectrum and Heimler syndrome: Deep phenotyping and review of the literature

  2020cites this paper
• An Overview of AAA+ Superfamily Proteins Associated Helicases

  2019cites this paper
• Direct visualization of the expression and localization of chlamydial effector proteins within infected host cells

  2018cites this paper
• Disruption of peroxisome function leads to metabolic stress, mTOR inhibition, and lethality in liver cancer cells.

  2018cites this paper
• Serine Proteases as Metabolic Regulators in Yeast

  2017cites this paper
• TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import

  2017cites this paper
• PEX6 is Expressed in Photoreceptor Cilia and Mutated in Deafblindness with Enamel Dysplasia and Microcephaly

  2016cites this paper
• Genetic Interactions between PEROXIN12 and Other Peroxisome-Associated Ubiquitination Components1[OPEN]

  2016cites this paper
• Genetic Interactions between PEROXIN 12 and Other Peroxisome-Associated Ubiquitination Components 1 [ OPEN ]

  2016cites this paper
• Structural and functional insights into the mechanism of the Pex1/6 complex

  2015cites this paper
• ATM Functions at the Peroxisome to Induce Pexophagy in Response to ROS

  2015cites this paper
• Conserved targeting information in mammalian and fungal peroxisomal tail-anchored proteins

  2015cites this paper
• Evolutionary loss of peroxisomes – not limited to parasites

  2015cites this paper
• Elevated growth temperature decreases levels of the PEX5 peroxisome-targeting signal receptor and ameliorates defects of Arabidopsis mutants with an impaired PEX4 ubiquitin-conjugating enzyme

  2015influential citation
• Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders.

  2014cites this paper
• Peroxisomal Ubiquitin-Protein Ligases Peroxin2 and Peroxin10 Have Distinct But Synergistic Roles in Matrix Protein Import and Peroxin5 Retrotranslocation in Arabidopsis1[W][OPEN]

  2014cites this paper
• Protein Transport In and Out of Plant Peroxisomes

  2014cites this paper
• Global Analysis of Condition-specific Subcellular Protein Distribution and Abundance*

  2013cites this paper
• Genetic Dissection of Peroxisome-Associated Matrix Protein Degradation in Arabidopsis thaliana

  2013cites this paper
• PTS1 Peroxisomal Import Pathway Plays Shared and Distinct Roles to PTS2 Pathway in Development and Pathogenicity of Magnaporthe oryzae

  2013cites this paper
• Arabidopsis glyoxylate reductase 1 is localized in the cytosol and not peroxisomes in plant cells

  2012cites this paper
• Characterization of two common 5' polymorphisms in PEX1 and correlation to survival in PEX1 peroxisome biogenesis disorder patients

  2011cites this paper
• Influence of Peroxisomal Import and Receptor Recycling of Peroxisomal Function

  2011cites this paper
• UBIQUITINATION AND DEUBIQUITINATION IN THE MAMMALIAN PEX5-MEDIATED PEROXISOMAL PROTEIN IMPORT PATHWAY

  2009cites this paper
• Peroxisome-associated matrix protein degradation in Arabidopsis

  2009influential citation
• Dynamic Changes in the Subcellular Distribution of Gpd1p in Response to Cell Stress*

  2009cites this paper
• Peroxisome Biogenesis and Function

  2009cites this paper
• Identification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disorders

  2009cites this paper
• Caracterização estrutural e funcional da PEX5P: implicações mecanísticas no processo de importação proteica para a matriz peroxissomal.

  2009influential citation
• Molecular components required for the targeting of PEX7 to peroxisomes in Arabidopsis thaliana.

  2009cites this paper
• Organelle interplay in peroxisomal disorders.

  2009cites this paper
• The AAA+ superfamily of functionally diverse proteins

  2008cites this paper
• Therapy of X-linked adrenoleukodystrophy

  2008cites this paper
• The peroxisome: still a mysterious organelle

  2008cites this paper
• The Peroxisome RING‐Finger Complex is Required for Meiocyte Formation in the Fungus Podospora anserina

  2008cites this paper
• Contribution of peroxisome-specific isoform of Lon protease in sorting PTS1 proteins to peroxisomes.

  2008cites this paper
• [Structure and function of peroxisomal tetrameric carbonyl reductase].

  2008cites this paper
• Lpx1p is a peroxisomal lipase required for normal peroxisome morphology

  2008cites this paper
• Characterisation of zinc-binding domains of peroxisomal RING finger proteins using size exclusion chromatography/inductively coupled plasma-mass spectrometry

  2007cites this paper
• Protein translocation into peroxisomes by ring‐shaped import receptors

  2007cites this paper
• A Conserved Cysteine Residue of Pichia pastoris Pex20p Is Essential for Its Recycling from the Peroxisome to the Cytosol*

  2007cites this paper
• Therapy of X-linked adrenoleukodystrophy

  2006cites this paper