5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  American Journal of Epidemiology

• Publication date

  2000-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1093/OXFORDJOURNALS.AJE.A010290PMID 10791559
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Metabolic and Molecular Bases of Inherited Disease

  2001cited by this paper
• Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention.

  2000cited by this paper
• Mortality risk in men is associated with a common mutation in the methylenetetrahydrofolate reductase gene (MTHFR)

  1999cited by this paper
• Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome.

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• Analysis of select folate pathway genes, PAX3, and human T in a Midwestern neural tube defect population.

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• A methylenetetrahydrofolate reductase gene polymorphism in ischaemic stroke and in carotid artery stenosis

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• A common mutation in the methylenetetrahydrofolate reductase gene and risk of coronary heart disease: results among U.S. men.

  1998cited by this paper
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  1998cited by this paper
• Analysis of the 677 C→T Mutation of the Methylenetetrahydrofolate Reductase Gene in Different Ethnic Groups

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• Methylenetetrahydrofolate reductase gene polymorphism and ischemic stroke in Japanese.

  1998cited by this paper
• The C677T mutation of the 5,10-methylenetetrahydrofolate reductase gene is a moderate risk factor for spina bifida in Italy.

  1998cited by this paper
• Susceptibility to spina bifida; an association study of five candidate genes

  1998cited by this paper
• The High Prevalence of Thermolabile 5-10 Methylenetetrahydrofolate Reductase (MTHFR) in Italians Is not Associated to an Increased Risk for Coronary Artery Disease (CAD)

  1998influential reference
• Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)

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• The Methylenetetrahydrofolate Reductase TT677 Genotype Is Associated with Venous Thrombosis Independently of the Coexistence of the FV Leiden and the Prothrombin

  1998cited by this paper
• Evaluation of the MTHFR C677T allele and the MTHFR gene locus in a German spina bifida population

  1998cited by this paper
• Absence of association between a common mutation in the methylenetetrahydrofolate reductase gene and the risk of coronary artery disease

  1998influential reference
• Low blood folates in NTD pregnancies are only partly explained by thermolabile 5,10-methylenetetrahydrofolate reductase: low folate status alone may be the critical factor.

  1998cited by this paper
• 677→CT mutation on the methylenetetrahydrofolate reductase gene is not a risk factor for neural tube defects in Turkey

  1998cited by this paper
• Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and cleft lip.

  1998influential reference
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• Factor V Leiden (G1691A), the Prothrombin 3’-Untranslated Region Variant (G20210A) and Thermolabile Methylenetetrahydrofolate Reductase (C677T): A Single Genetic Test Genotypes all Three Loci – Determination of Frequencies in the S. Wales Population of the UK

  1998influential reference
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  1998cited by this paper
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  1998influential reference
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  1998influential reference
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  1998cited by this paper
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  1998influential reference
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  1998cited by this paper
• Worldwide distribution of a common methylenetetrahydrofolate reductase mutation.

  1998influential reference
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  1998cited by this paper
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  1998cited by this paper
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  1998influential reference
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  1998cited by this paper
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  1998cited by this paper
• Is the common 677C-->T mutation in the methylenetetrahydrofolate reductase gene a risk factor for neural tube defects? A meta-analysis.

  1997cited by this paper
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  1997cited by this paper
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  1997influential reference
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  1997influential reference
• The 677C-->T mutation in the methylenetetrahydrofolate reductase gene: associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease.

  1997influential reference
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  1997cited by this paper
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  1997influential reference
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997influential reference
• [Gene Polymorphism of 5, 10-methylenetetrahydrofolate reductase as a coronary risk factor].

  1997cited by this paper
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  1997influential reference
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  1997influential reference
• Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease.

  1997cited by this paper
• The Mutation Ala677→Val in the Methylene Tetrahydrofolate Reductase Gene: A Risk Factor for Arterial Disease and Venous Thrombosis

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  1997influential reference
• C677T (thermolabile alanine/valine) polymorphism in methylenetetrahydrofolate reductase (MTHFR): its frequency and impact on plasma homocysteine concentration in different European populations. EARS group.

  1997cited by this paper
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  1997influential reference
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  1997influential reference
• A common mutation in the methylenetetrahydrofolate reductase gene (C677T) increases the risk for deep-vein thrombosis in patients with mutant factor V (factor V:Q506).

  1997influential reference
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  1996cited by this paper
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  1996influential reference
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  1996cited by this paper
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  1996influential reference
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  1996influential reference
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  1996influential reference
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  1996cited by this paper
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  1996influential reference
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  1996influential reference
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  1995cited by this paper
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  1995cited by this paper
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