START domain proteins and the intracellular trafficking of cholesterol in steroidogenic cells.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Molecular and Cellular Endocrinology

• Publication date

  2003-04-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0303-7207(03)00063-7PMID 12770731
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6

  2002cited by this paper
• Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain

  2002cited by this paper
• Rapid regulation of steroidogenesis by mitochondrial protein import

  2002cited by this paper
• MLN64 Mediates Mobilization of Lysosomal Cholesterol to Steroidogenic Mitochondria* 210

  2002cited by this paper
• Steroidogenic Acute Regulatory Protein Binds Cholesterol and Modulates Mitochondrial Membrane Sterol Domain Dynamics*

  2001cited by this paper
• Quantitative Analysis of the Hormone-induced Hyperacetylation of Histone H3 Associated with the Steroidogenic Acute Regulatory Protein Gene Promoter*

  2001cited by this paper
• The Steroidogenic Acute Regulatory Protein Homolog MLN64, a Late Endosomal Cholesterol-binding Protein*

  2001cited by this paper
• Binding of Steroidogenic Acute Regulatory Protein to Synthetic Membranes Suggests an Active Molten Globule*

  2001cited by this paper
• Structure and lipid transport mechanism of a StAR-related domain

  2000cited by this paper
• Identification of HE1 as the second gene of Niemann-Pick C disease.

  2000cited by this paper
• NPC1-containing compartment of human granulosa-lutein cells: a role in the intracellular trafficking of cholesterol supporting steroidogenesis.

  2000cited by this paper
• Steroidogenic acute regulatory protein (StAR) and the intramitochondrial translocation of cholesterol.

  2000cited by this paper
• The Niemann-Pick C1 Protein Resides in a Vesicular Compartment Linked to Retrograde Transport of Multiple Lysosomal Cargo*

  1999cited by this paper
• The Mechanism of Action of Steroidogenic Acute Regulatory Protein (StAR)

  1998cited by this paper
• Steroidogenic Acute Regulatory Protein (StAR) Is A Sterol Transfer Protein*

  1998cited by this paper
• Phosphorylation of Steroidogenic Acute Regulatory Protein (StAR) Modulates Its Steroidogenic Activity*

  1997cited by this paper
• Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia.

  1997cited by this paper
• Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis.

  1997cited by this paper
• MLN64 contains a domain with homology to the steroidogenic acute regulatory protein (StAR) that stimulates steroidogenesis.

  1997cited by this paper
• Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis.

  1995cited by this paper

• Lipid droplets-mitochondria interaction involved in testosterone synthesis in Leydig cells of dairy goats (Capra hircus).

  2025cites this paper
• Multifaceted landscape of the StAR protein in steroid biosynthesis: from development to degeneration.

  2025cites this paper
• Is There Conservation of Vitellogenins in a Placentotrophic Lizard?

  2025cites this paper
• Cotton STARD Gene Family: Characterization, Evolution, and Expression Profiles During Salt Stress

  2025cites this paper
• Propolis extract nanoparticles alleviate diabetes-induced reproductive dysfunction in male rats: antidiabetic, antioxidant, and steroidogenesis modulatory role

  2024cites this paper
• Steroidogenic Acute Regulatory Protein Mediated Variations of Gender-Specific Sex Neurosteroids in Alzheimer's Disease: Relevance to Hormonal Imbalance.

  2024cites this paper
• Expression and Function of StAR in Cancerous and Non-Cancerous Human and Mouse Breast Tissues: New Insights into Diagnosis and Treatment of Hormone-Sensitive Breast Cancer

  2023cites this paper
• SREBF2–STARD4 axis confers sorafenib resistance in hepatocellular carcinoma by regulating mitochondrial cholesterol homeostasis

  2022cites this paper
• Evolutionary relationship analysis of STARD gene family and VvSTARD5 improves tolerance of salt stress in transgenic tomatoes.

  2022cites this paper
• Role of STAR and SCP2/SCPx in the Transport of Cholesterol and Other Lipids

  2022cites this paper
• Dysregulation of cellular membrane homeostasis as a crucial modulator of cancer risk

  2022cites this paper
• Evolutionary Analysis of the Steroidogenic Acute Regulatory Protein-Related Lipid Transfer Domain and Its Response to Salt Stress In Vitis Vinifera

  2021cites this paper
• Intermembrane Translocation of Photodynamically Generated Lipid Hydroperoxides: Broadcasting of Redox Damage †

  2021cites this paper
• Extra-adrenal glucocorticoid biosynthesis: Implications for autoimmune and inflammatory disorders.

  2020cites this paper
• Identifying genes associated with the development of human polycystic ovary syndrome

  2020cites this paper
• Analysis of phospholipid synthesis in mitochondria.

  2020cites this paper
• Cholesterol homeostasis: researching a dialogue between the brain and peripheral tissues.

  2020cites this paper
• The macular carotenoids: A biochemical overview.

  2020cites this paper
• Genetic polymorphisms associated with polycystic ovary syndrome among Iranian women

  2020cites this paper
• Membrane Lipid Composition: Effect on Membrane and Organelle Structure, Function and Compartmentalization and Therapeutic Avenues

  2019cites this paper
• Proteolytic Control of Lipid Metabolism.

  2019cites this paper
• The Effects of Fish Meal Supplementation on Gene Expression in the Bovine Corpus Luteum Following Low Dose Administration of Prostaglandin F2A

  2019cites this paper
• Aspectos generales del transporte de colesterol en la esteroidogénesis de la placenta humana

  2019cites this paper
• Mitochondrial Dysfunctions: A Thread Sewing Together Alzheimer's Disease, Diabetes, and Obesity

  2019cites this paper
• Genomic Profiling of the Steroidogenic Acute Regulatory Protein in Breast Cancer: In Silico Assessments and a Mechanistic Perspective

  2019cites this paper
• Transcription regulation of NRF1 on StAR reduces testosterone synthesis in hypoxemic murine.

  2019cites this paper
• Lipid bilayer stress in obesity‐linked inflammatory and metabolic disorders

  2018cites this paper
• Regulation of Adrenal Steroidogenesis

  2018cites this paper
• Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis

  2017cites this paper
• Measurement of Mitochondrial Cholesterol Import Using a Mitochondria-Targeted CYP11A1 Fusion Construct.

  2017cites this paper
• MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content

  2017cites this paper
• The role of cellular lipid homeostasis in the hepatitis C virus replication cycle

  2017cites this paper
• Mitochondrial cholesterol import.

  2017cites this paper
• Interacción colesterol-gangliósido GD3 en la fibrosis hepática

  2017cites this paper
• PPP1, a plant-specific regulator of transcription controls Arabidopsis development and PIN expression

  2016cites this paper
• Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function

  2016cites this paper
• Retraction Note: PPP1, a plant-specific regulator of transcription controls Arabidopsis development and PIN expression

  2016cites this paper
• High-yield soluble expression, purification and characterization of human steroidogenic acute regulatory protein (StAR) fused to a cleavable Maltose-Binding Protein (MBP).

  2016cites this paper
• Female Reproductive Physiology

  2015cites this paper
• Role of the steroidogenic acute regulatory protein in health and disease

  2015cites this paper
• Characterization of STARD4 and STARD6 Proteins in Human Ovarian Tissue and Human Granulosa Cells and Cloning of Human STARD4 Transcripts

  2015cites this paper
• Multiple functions of syncytiotrophoblast mitochondria.

  2015cites this paper
• No relationship between most polymorphisms of steroidogenic acute regulatory (StAR) gene with polycystic ovarian syndrome

  2015cites this paper
• The STARD4 Subfamily: STARD4 and STARD5 in Cholesterol Metabolism

  2014cites this paper
• An Introduction to the Steroidogenic Acute Regulatory Protein (StAR)-Related Lipid Transfer Domain Protein Family

  2014cites this paper
• Steroidogenic Acute Regulatory Protein-related Lipid Transfer (START) Proteins in Non-vesicular Cholesterol Transport

  2014cites this paper
• The StarD4 subfamily of steroidogenic acute regulatory-related lipid transfer (START) domain proteins: new players in cholesterol metabolism.

  2014cites this paper
• Estrus synchronization and ovarian hyper‐stimulation treatments have negligible effects on cumulus oocyte complex gene expression whereas induction of ovulation causes major expression changes

  2013cites this paper
• START-GAP/DLC Family Proteins: Molecular Mechanisms for Anti-Tumor Activities

  2013cites this paper
• Organelle plasticity and interactions in cholesterol transport and steroid biosynthesis.

  2013cites this paper
• Thermodynamic and solution state NMR characterization of the binding of secondary and conjugated bile acids to STARD5.

  2013cites this paper
• Structural and functional aspects of PR‐10 proteins

  2013cites this paper
• Global gene expression in the bovine corpus luteum is altered after stimulatory and superovulatory treatments.

  2013cites this paper
• The HER2 amplicon in breast cancer: Topoisomerase IIA and beyond.

  2013cites this paper
• Drug ligand-induced activation of translocator protein (TSPO) stimulates steroid production by aged brown Norway rat Leydig cells.

  2013cites this paper
• Conséquence d'une carence gestationnelle en donneurs de méthyles sur l'expression des protéines clés de la neurostéroïdogenèse chez le rat

  2013cites this paper
• Investigation of START Domain Proteins in Human Luteinized Cells and COS-1 Cells

  2013cites this paper
• Transport and Retinal Capture of the Macular Carotenoids

  2013cites this paper
• STARD5 specific ligand binding: comparison with STARD1 and STARD4 subfamilies.

  2013cites this paper
• STARD4 knockdown in HepG2 cells disrupts cholesterol trafficking associated with the plasma membrane, ER, and ERC

  2012cites this paper
• StAR-related lipid transfer domain protein 5 binds primary bile acids[S]

  2012cites this paper
• Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes

  2012cites this paper
• ER stress increases StarD5 expression by stabilizing its mRNA and leads to relocalization of its protein from the nucleus to the membranes

  2012cites this paper
• The mammalian START domain protein family in lipid transport in health and disease.

  2012cites this paper
• Bile Formation and the Enterohepatic Circulation

  2012cites this paper
• Gene expression analysis of toxicological pathways in TM3 leydig cell lines treated with Ethane dimethanesulfonate

  2012cites this paper
• Translocator protein as a promising target for novel anxiolytics.

  2012cites this paper
• Metabolism and translocation of aminophospholipids in mammalian cells

  2012cites this paper
• Exosomes act as molecular vehicles contributing to cellular cholesterol efflux

  2011cites this paper
• Mitochondrial protein import and the genesis of steroidogenic mitochondria.

  2011cites this paper
• The in Vivo and in Vitro Stimulatory Effects of Cordycepin on Mouse Leydig Cell Steroidogenesis

  2011cites this paper
• Deleted in liver cancer protein family in human malignancies (Review).

  2011cites this paper
• JCB: Review

  2011cites this paper
• Osh Proteins Regulate Membrane Sterol Organization but Are Not Required for Sterol Movement Between the ER and PM

  2011cites this paper
• Making heads or tails of phospholipids in mitochondria

  2011cites this paper
• Effects of sesamol on apoptosis and steroidogenesis in MA-10 mouse Leydig tumor cells.

  2011cites this paper
• Subcellular localization and regulation of StarD4 protein in macrophages and fibroblasts.

  2011cites this paper
• STARD4 abundance regulates sterol transport and sensing

  2011cites this paper
• articleDownregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFδ / δ mouse model of amyotrophic lateral sclerosis

  2010cites this paper
• High-throughput computational structure-based characterization of protein families: START domains and implications for structural genomics

  2010cites this paper
• Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFδ/δ mouse model of amyotrophic lateral sclerosis

  2010cites this paper
• Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease.

  2010cites this paper
• 17q12-21 - the pursuit of targeted therapy in breast cancer.

  2010cites this paper
• Sterols and sphingolipids: dynamic duo or partners in crime?

  2010cites this paper
• Effect of Plastoquinone Derivative 10-(6′-Plastoquinonyl)decyltriphenylphosphonium (SkQ1) on Contents of Steroid Hormones and NO Level in Rats

  2010cites this paper
• Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones

  2010cites this paper
• Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism[S]

  2010cites this paper
• Biliary cholesterol secretion: more than a simple ABC.

  2010cites this paper
• Regulation of the steroidogenic acute regulatory protein gene expression: present and future perspectives.

  2009cites this paper
• Validation of the mechanism of cholesterol binding by StAR using short molecular dynamics simulations.

  2009cites this paper
• Cholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states.

  2009cites this paper
• The mechanism of specific binding of free cholesterol by the steroidogenic acute regulatory protein: evidence for a role of the C-terminal alpha-helix in the gating of the binding site.

  2009cites this paper
• mucolipidosis type IV pathogenesis Membrane traffic and turnover in TRP-ML1-deficient cells: a revised model for

  2009cites this paper
• SR-BI-mediated HDL cholesteryl ester delivery in the adrenal gland.

  2009cites this paper
• Temporal expression of progesterone and proteins associated with prostaglandin F2alpha-induced luteolysis in the sheep

  2009cites this paper
• Molecular cloning and expression of steroidogenic acute regulatory protein from bullfrog (Rana catesbeiana).

  2009cites this paper
• Toward the NMR structure of StAR.

  2009cites this paper
• Lipid assembly into cell membranes

  2008cites this paper
• Cholesterol interaction with the related steroidogenic acute regulatory lipid‐transfer (START) domains of StAR (STARD1) and MLN64 (STARD3)

  2008cites this paper
• Production and application of a polyclonal peptide antiserum for universal detection of StAR protein.

  2008cites this paper