Update on nonalcoholic fatty liver disease.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Journal of Clinical Gastroenterology

• Publication date

  2002-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/00004836-200203000-00013PMID 11873108
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nonalcoholic steatohepatitis in obesity: a reversible condition.

  2009cited by this paper
• Trends in body weight and overweight in the U.S. population.

  2009cited by this paper
• Nonalcoholic steatohepatitis

  2004cited by this paper
• Nonalcoholic steatohepatitis in children

  2003cited by this paper
• Nonalcoholic fatty liver disease: a feature of the metabolic syndrome.

  2001influential reference
• Animal Models of Steatosis

  2001cited by this paper
• Peroxisomal beta-oxidation and steatohepatitis.

  2001cited by this paper
• Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities.

  2001cited by this paper
• Ursodiol Use Is Associated with Lower Prevalence of Colonic Neoplasia in Patients with Ulcerative Colitis and Primary Sclerosing Cholangitis

  2001cited by this paper
• Mitochondrial oxidative injury and energy metabolism alteration in rat fatty liver: Effect of the nutritional status

  2001cited by this paper
• Treatment of Nonalcoholic Fatty Liver: Present and Emerging Therapies

  2001cited by this paper
• Mitochondria in Steatohepatitis

  2001cited by this paper
• Diagnosis and management of hemochromatosis

  2001cited by this paper
• Obesity and female gender increase breath ethanol concentration: potential implications for the pathogenesis of nonalcoholic steatohepatitis

  2001cited by this paper
• Etiopathogenesis of Nonalcoholic Steatohepatitis

  2001cited by this paper
• Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus.

  2001cited by this paper
• Peroxisomal β-Oxidation and Steatohepatitis

  2001cited by this paper
• A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis

  2001cited by this paper
• Clinical Features and Natural History of Nonalcoholic Steatosis Syndromes

  2001cited by this paper
• Nonalcoholic steatohepatitis in children.

  2000cited by this paper
• Obesity as a medical problem

  2000cited by this paper
• CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis.

  2000cited by this paper
• Oxidant stress in rat liver after lipopolysaccharide administration: effect of inducible nitric-oxide synthase inhibition.

  2000cited by this paper
• Changes in microsomal activity in alcoholism and obesity.

  2000cited by this paper
• Concise Review for CliniciansNonalcoholic Steatohepatitis

  2000cited by this paper
• Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: A case‐control study

  2000cited by this paper
• Betaine for the treatment of nonalcoholic steatohepatitis: A promising new agent

  2000cited by this paper
• Bioavailability of four ursodeoxycholic acid preparations

  2000cited by this paper
• Prevalence of and Risk Factors for Hepatic Steatosis in Northern Italy

  2000cited by this paper
• Metformin reverses fatty liver disease in obese, leptin-deficient mice

  2000cited by this paper
• Treatment of non-alcoholic steatohepatitis with N-acetyl cystein

  2000cited by this paper
• Mitochondrial adaptations to obesity-related oxidant stress.

  2000cited by this paper
• Vitamin E treatment of nonalcoholic steatohepatitis in children: a pilot study.

  2000cited by this paper
• Liver fibrosis in overweight patients.

  2000cited by this paper
• Metabolic and nutritional considerations in nonalcoholic fatty liver

  2000cited by this paper
• Nonalcoholic steatohepatitis.

  2000cited by this paper
• Hepatic stellate cell activation in nonalcoholic steatohepatitis and fatty liver.

  2000cited by this paper
• Hepatocellular Injury in a Patient Receiving Rosiglitazone: A Case Report

  2000cited by this paper
• Increased gastrointestinal ethanol production in obese mice: implications for fatty liver disease pathogenesis.

  2000cited by this paper
• Leptin deficiency enhances sensitivity to endotoxin-induced lethality.

  1999cited by this paper
• Body composition and hepatic steatosis as precursors for fibrotic liver disease

  1999cited by this paper
• Association of nonalcoholic fatty liver disease with insulin resistance.

  1999influential reference
• Non-alcoholic steatohepatitis and iron: increased prevalence of mutations of the HFE gene in non-alcoholic steatohepatitis.

  1999cited by this paper
• A controlled trial of gemfibrozil in the treatment of patients with nonalcoholic steatohepatitis.

  1999cited by this paper
• Cryptogenic cirrhosis: Clinical characterization and risk factors for underlying disease

  1999cited by this paper
• Comparison of serum concentrations of α-tocopherol and β-carotene in a cross-sectional sample of obese and nonobese children (NHANES III)

  1999cited by this paper
• Ursodeoxycholic acid protects hepatocytes against oxidative injury via induction of antioxidants.

  1999cited by this paper
• Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions

  1999cited by this paper
• Obesity Induces Expression of Uncoupling Protein-2 in Hepatocytes and Promotes Liver ATP Depletion*

  1999cited by this paper
• Schiff's diseases of the liver

  1999cited by this paper
• Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study.

  1999cited by this paper
• Mechanism of hepatoprotective action of bile salts in liver disease.

  1999cited by this paper
• Hepatic iron and nonalcoholic fatty liver disease

  1999cited by this paper
• Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis

  1999cited by this paper
• Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity.

  1999influential reference
• Withdrawal of life support, altruistic suicide, fratricidal killing and euthanasia by lymphocytes: different forms of drug-induced hepatic apoptosis.

  1999cited by this paper
• The ratio of aspartate aminotransferase to alanine aminotransferase: potential value in differentiating nonalcoholic steatohepatitis from alcoholic liver disease

  1999cited by this paper
• Comparison of serum concentrations of alpha-tocopherol and beta-carotene in a cross-sectional sample of obese and nonobese children (NHANES III). National Health and Nutrition Examination Survey.

  1999cited by this paper
• Leptin deficiency enhances sensitivity to endotoxin-induced lethality.

  1999cited by this paper
• A Risk-Benefit Assessment of Anti-Obesity Drugs

  1999cited by this paper
• Hepatic steatosis: Innocent bystander or guilty party?

  1998cited by this paper
• Cytokine Expression in Hepatocytes: Role of Oxidant Stress

  1998cited by this paper
• Steatohepatitis: a tale of two "hits"?

  1998cited by this paper
• Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

  1998cited by this paper
• Alcoholic liver disease: proposed recommendations for the American College of Gastroenterology

  1998cited by this paper
• Liver and biliary ultrasonography in diabetic and non-diabetic obese women.

  1998cited by this paper
• Identification of a Transforming Growth Factor-β1/Bone Morphogenetic Protein 4 (TGF-β1/BMP4) Response Element within the Mouse Tissue Transglutaminase Gene Promoter*

  1998cited by this paper
• Unsuspected cirrhosis discovered during elective obesity operations.

  1998cited by this paper
• Peripheral pulmonary adenocarcinomas with bronchioloalveolar features: immunophenotypes correlate with histologic patterns.

  1998cited by this paper
• Liver and biliary ultrasonography in diabetic and non-diabetic obese women.

  1998cited by this paper
• Nonalcoholic fatty liver disease: assessment of variability in pathologic interpretations.

  1998cited by this paper
• Transdifferentiation of rat hepatic stellate cells results in leptin expression.

  1998cited by this paper
• Hepatic dysfunction associated with troglitazone.

  1998cited by this paper
• Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis.

  1998cited by this paper
• Gender-dependent alterations in serum leptin in alcoholic cirrhosis.

  1998cited by this paper
• Mallory body formation by ethanol feeding in drug‐primed mice

  1998cited by this paper
• Nonalcoholic steatohepatitis.

  1997cited by this paper
• Therapeutic effects of restricted diet and exercise in obese patients with fatty liver.

  1997cited by this paper
• Liver Involvement in Obese Children (Ultrasonography and Liver Enzyme Levels at Diagnosis and During Follow-up in an Italian Population)

  1997cited by this paper
• Nonalcoholic fatty liver (NASH syndrome).

  1997cited by this paper
• Excess weight risk factor for alcoholic liver disease

  1997cited by this paper
• Drinking habits as cofactors of risk for alcohol induced liver damage

  1997cited by this paper
• The bright liver syndrome. Prevalence and determinants of a "bright" liver echopattern.

  1997cited by this paper
• Varying body mass index cutoff points to describe overweight prevalence among U.S. adults: NHANES III (1988 to 1994).

  1997cited by this paper
• Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis.

  1997cited by this paper
• Activation of CPP32-like protease in tumor necrosis factor-induced apoptosis is dependent on mitochondrial function.

  1997cited by this paper
• The lipid peroxidation end product 4‐hydroxy‐2,3‐nonenal up‐regulates transforming growth factor β1 expression in the macrophage lineage: a link between oxidative injury and fibrosclerosis 1

  1997cited by this paper
• Study of human isoursodeoxycholic acid metabolism.

  1997cited by this paper
• Acute and chronic hepatic steatosis lead to in vivo lipid peroxidation in mice.

  1996cited by this paper
• The OB Protein (Leptin) Pathway - A Link Between Adipose Tissue Mass and Central Neural Networks

  1996cited by this paper
• Ursodeoxycholic acid or clofibrate in the treatment of non‐alcohol‐induced steatohepatitis: A pilot study

  1996cited by this paper
• Prediction of risk of liver disease by alcohol intake, sex, and age: A prospective population study

  1996cited by this paper
• The natural history of nonalcoholic fatty liver: A follow‐up study

  1995cited by this paper
• Nonalcoholic steatohepatitis: an expanded clinical entity: Bacon BR, Farakvash MJ, Janney CG, Neuschwander-Tetri BA. Gastroenterology 1994; 107: 1103–1109

  1995cited by this paper
• Nuclear migration of NF-kappa B correlates with TNF-alpha mRNA accumulation.

  1995cited by this paper
• Nonalcoholic steatohepatitis: Tightening the morphological screws on a hepatic rambler

  1995cited by this paper
• Nonalcoholic steatohepatitis: tightening the morphological screws on a hepatic rambler.

  1995cited by this paper
• Nuclear migration of NF-κB correlates with TNF-α mRNA accumulation

  1995cited by this paper
• Two cases from the spectrum of nonalcoholic steatohepatitis.

  1995cited by this paper
• Idiopathic steatohepatitis in childhood: a multicenter retrospective study.

  1995cited by this paper

• Non-Alcoholic Fatty Liver Disease and Possibilities of Its Therapy (Review)

  2026cites this paper
• Correlation Between Liver-to-Spleen Hounsfield Unit Ratio and Metabolic Improvement in Patients With Bariatric Surgery

  2025cites this paper
• Serum gamma-glutamyl transferase level is associated with the risk of pancreatic cystic neoplasms: A nationwide retrospective cohort study

  2025cites this paper
• Nonalcoholic fatty liver disease and associated risk factors in obese Nigerians: A cross-sectional study

  2024cites this paper
• Feasibility of joint mapping of triglyceride saturation and water longitudinal relaxation in a single breath hold applied to high fat-fraction adipose depots in the periclavicular anatomy.

  2023cites this paper
• THE EFFECT OF FATTY LIVER DISEASE ON PORTAL VEIN FLOW IN OBESE ADOLESCENTS

  2023cites this paper
• Palmitate로 유발된 비알코올성 지방간 세포 모델에서 블랙커런트 초임계 추출물의 지방증 개선효과

  2023cites this paper
• The Role of Bifidobacterium in Liver Diseases: A Systematic Review of Next-Generation Sequencing Studies

  2023cites this paper
• Acetyl-CoA carboxylase inhibitor increases LDL-apoB production rate in NASH with cirrhosis: prevention by fenofibrate

  2023cites this paper
• Sex difference in the associations among liver function parameters with incident diabetes mellitus in a large Taiwanese population follow-up study

  2023influential citation
• Comparative Study of Serum Levels of Gamma-glutamyl Transferase, Aspartate Aminotransferase (AST), Alanine Transaminase (ALT), AST:ALT, and Bilirubin in Patients with Chronic Hepatitis

  2023cites this paper
• Elevated serum γ-glutamyl transferase is associated with low muscle function in adults independent of muscle mass.

  2022cites this paper
• Changes in abdominal adipose tissue depots accessed by MRI correlate with hepatic histologic improvement in non-alcoholic steatohepatitis.

  2022cites this paper
• Potential cytotoxic effect of caffeinated and non-caffeinated carbonated soft drinks on liver and pancreas of adult male Albino rats; (biochemical, histological and DNA study)

  2022cites this paper
• Determination of Chemotherapy Associated Fatty Liver Disease Among Colorectal Cancer Patients by Non-Invasive Methods

  2022cites this paper
• Apolipoprotein A4 Restricts Diet-induced Hepatic Steatosis via SREBF1-mediated Lipogenesis and Enhances IRS-PI3K-Akt Signaling.

  2022cites this paper
• The Serum Levels of IL-1\beta, IL-6, IL-8 and TNF-\alpha in Nonalcoholic Fatty Liver

  2022cites this paper
• Risk factors for chronic liver disease in population of Central India: a case-control study from rural India

  2021cites this paper
• Non-invasive Methods in Diagnosis of Nonalcoholic Fatty Liver Disease

  2021influential citation
• Abnormal Liver Biochemistry Tests and Acute Liver Injury in COVID-19 Patients: Current Evidence and Potential Pathogenesis

  2021cites this paper
• Does the FT3-to-FT4 ratio easily predict the progression of NAFLD and NASH cirrhosis?

  2021cites this paper
• Properties of Plasma Clots in Adult Patients Following Fontan Procedure: Relation to Clot Permeability and Lysis Time—Multicenter Study

  2021cites this paper
• The importance of Cyclophilins and Mps1 in cancer

  2021cites this paper
• Does a high intake of green leafy vegetables protect from NAFLD? Evidence from a large population study.

  2021cites this paper
• Magnetic resonance biomarkers in radiation oncology: The report of AAPM Task Group 294

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  2020cites this paper
• Quantification of liver fat content with ultrasonographic attenuation measurement function: Correlation with unenhanced multidimensional computerized tomography.

  2020cites this paper
• The Effect of Resveratrol Supplementation on Improving Non-Alcoholic Fatty Liver: A Review on Randomized Clinical Trials

  2020cites this paper
• Evaluation of Hepatic Steatosis with CT and Correlation with Anthropometric Measurements.

  2020cites this paper
• Secreted phosphoglucose isomerase is a novel biomarker of nonalcoholic fatty liver in mice and humans

  2020cites this paper
• The dark side of gamma-glutamyltransferase (GGT): Pathogenic effects of an 'antioxidant' enzyme.

  2020cites this paper
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  2020cites this paper
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  2020cites this paper
• Sugar-free Workplace: A Step for Fighting Obesity

  2019cites this paper
• Optimal Evaluation of the Results of Liver Function Tests

  2019cites this paper
• The effect of omega-3 supplementation on glycemic indices and lipid profile in type 2 diabetic patients with non-alcoholic fatty liver disease: A double-blind, randomized, clinical trial

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018influential citation
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017influential citation
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  2017cites this paper
• Traditional Markers in Liver Disease

  2017cites this paper
• Effects of ginsenoside Rg1 on glucose metabolism and liver injury in streptozotocin-induced type 2 diabetic rats.

  2017cites this paper
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  2016cites this paper
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  2016cites this paper
• Acidophil bodies in nonalcoholic steatohepatitis.

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• Quantitative Proteomic Investigation of Disease Models of Type 2 Diabetes

  2016cites this paper
• [[The Modern View on Pathogenesis and Treatment of Nonalcoholic Fatty Liver Disease].]

  2016cites this paper
• Growth Trajectories of Refugee and Nonrefugee Children in the United States

  2016cites this paper
• The Liver-Impaired Patient

  2015cites this paper
• Ultrasound, anthropometry and bioimpedance: a comparison in predicting fat deposition in non-alcoholic fatty liver disease

  2015cites this paper
• Enhanced liver fibrosis (ELF) test in obese children with ultrasound-proven liver steatosis.

  2015influential citation
• Physical Activity is Related to Fatty Liver Marker in Obese Youth, Independently of Central Obesity or Cardiorespiratory Fitness.

  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
• Non-alcoholic fatty liver disease: The diagnosis and management.

  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper