Cell death and immunity: Apoptosis as an HIV strategy to escape immune attack

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Nature reviews. Immunology

• Publication date

  2003-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nri1087PMID 12766761
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Therapeutic dendritic-cell vaccine for simian AIDS

  2003cited by this paper
• Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions

  2003cited by this paper
• Decision making in the immune system: The lineage decisions of helper T cells

  2002cited by this paper
• Longitudinal evolution of HIV‐1‐associated lipodystrophy is correlated to serum cortisol:DHEA ratio and IFN‐α

  2002cited by this paper
• CD4 T Cell Depletion Is Linked Directly to Immune Activation in the Pathogenesis of HIV-1 and HIV-2 but Only Indirectly to the Viral Load1

  2002cited by this paper
• HIV Antigens Can Induce TGF-β1-Producing Immunoregulatory CD8+ T Cells1

  2002cited by this paper
• Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV‐1 envelope

  2002cited by this paper
• Stromal cell-derived factor 1/CXCR4 signaling is critical for early human T-cell development.

  2002cited by this paper
• Interleukin-7-treated naive T cells can be productively infected by T-cell-adapted and primary isolates of human immunodeficiency virus 1.

  2002cited by this paper
• Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: relation to expression of Bcl-2 and active caspase-8 and caspase-3.

  2002cited by this paper
• Lymphocide: cytokines and the control of lymphoid homeostasis

  2002cited by this paper
• HIV antigens can induce TGF-beta(1)-producing immunoregulatory CD8+ T cells.

  2002cited by this paper
• Molecular mechanisms of activated T cell death in vivo.

  2002cited by this paper
• Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

  2002cited by this paper
• Effects of Antiretroviral Drugs on Human Immunodeficiency Virus Type 1-Induced CD4+ T-Cell Death

  2002cited by this paper
• HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication

  2002cited by this paper
• HIV preferentially infects HIV-specific CD4+ T cells

  2002cited by this paper
• HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

  2002cited by this paper
• CD4 lymphocytes in the blood of HIV+ individuals migrate rapidly to lymph nodes and bone marrow: support for homing theory of CD4 cell depletion

  2002cited by this paper
• Live and let die: Nef functions beyond HIV replication.

  2002cited by this paper
• In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: Why are CD4+ but not CD8+ T cells depleted?

  2002cited by this paper
• Influence of mitochondrial control of apoptosis on the pathogenesis, complications and treatment of HIV infection.

  2002cited by this paper
• Cytopathic Killing of Peripheral Blood CD4+ T Lymphocytes by Human Immunodeficiency Virus Type 1 Appears Necrotic rather than Apoptotic and Does Not Require env

  2002cited by this paper
• CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

  2002cited by this paper
• Development of alphabeta T cells in the human thymus.

  2002cited by this paper
• Lack of control of T cell apoptosis under HAART. Influence of therapy regimen in vivo and in vitro

  2002cited by this paper
• CD4+ T helper cells and the role they play in viral control

  2002cited by this paper
• Structured intermittent treatment for HIV disease: Necessary concession or premature compromise?

  2002cited by this paper
• CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause?

  2002cited by this paper
• Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance.

  2002cited by this paper
• To kill or be killed: viral evasion of apoptosis

  2002cited by this paper
• Development of αβ T cells in the human thymus

  2002cited by this paper
• Antitumorigenic effects of HIV protease inhibitor ritonavir: inhibition of Kaposi sarcoma.

  2002cited by this paper
• Effects of exogenous interleukin-7 on human thymus function.

  2002cited by this paper
• The dynamics of CD4+ T-cell depletion in HIV disease

  2001cited by this paper
• Tumor Necrosis Factor a and Interleukin 11 Secreted by Malignant Breast Epithelial Cells Inhibit Adipocyte Differentiation by Selectively Down- Regulating CCAAT/Enhancer Binding Protein a and Peroxisome Proliferator-activated Receptor g: Mechanism of Desmoplastic Reaction

  2001cited by this paper
• Induction of Cell Death in Human Immunodeficiency Virus-Infected Macrophages and Resting Memory CD4 T Cells by TRAIL/Apo2L

  2001cited by this paper
• Induction of antigen‐specific human CD4+ T cell anergy by peripheral blood DC2 precursors

  2001cited by this paper
• Immunological and virological effects of long term IL-2 therapy in HIV-1-infected patients.

  2001cited by this paper
• Plasmacytoid Dendritic Cells Are Highly Susceptible to Human Immunodeficiency Virus Type 1 Infection and Release Infectious Virus

  2001cited by this paper
• Increased CD95/Fas-induced apoptosis of HIV-specific CD8(+) T cells.

  2001cited by this paper
• Cellular immune responses to HIV

  2001cited by this paper
• High-level HIV-1 viremia suppresses viral antigen-specific CD4+ T cell proliferation

  2001cited by this paper
• Apoptosis Enhancement by the HIV-1 Nef Protein1

  2001cited by this paper
• Increased Turnover of T Lymphocytes in HIV-1 Infection and Its Reduction by Antiretroviral Therapy

  2001cited by this paper
• Critical Contribution of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) to Apoptosis of Human Cd4+T Cells in HIV-1–Infected Hu-Pbl-Nod-Scid Mice

  2001cited by this paper
• Breaking the mitochondrial barrier

  2001cited by this paper
• Evidence for Increased T Cell Turnover and Decreased Thymic Output in HIV Infection1

  2001cited by this paper
• Identification of a Potential HIV-Induced Source of Bystander-Mediated Apoptosis in T Cells: Upregulation of TRAIL in Primary Human Macrophages by HIV-1 Tat

  2001cited by this paper
• Biochemical mechanisms of HIV induced T cell apoptosis

  2001cited by this paper
• Identification of a potential HIV-induced source of bystander-mediated apoptosis in T cells: upregulation of trail in primary human macrophages by HIV-1 tat.

  2001cited by this paper
• Increased production of IL-7 accompanies HIV-1–mediated T-cell depletion: implications for T-cell homeostasis

  2001cited by this paper
• Apoptosis Control in Syncytia Induced by the HIV Type 1–Envelope Glycoprotein Complex

  2000cited by this paper
• CD95's deadly mission in the immune system

  2000cited by this paper
• Immune control of HIV-1 after early treatment of acute infection

  2000cited by this paper
• In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline.

  2000cited by this paper
• Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection

  2000cited by this paper
• The HIV-1 Viral Protein R Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore

  2000cited by this paper
• HIV-1 envelope induces activation of caspase-3 and cleavage of focal adhesion kinase in primary human CD4(+) T cells.

  2000cited by this paper
• Effect of recent thymic emigrants on progression of HIV-1 disease.

  2000cited by this paper
• Reduced immune activation and T cell apoptosis in human immunodeficiency virus type 2 compared with type 1: correlation of T cell apoptosis with beta2 microglobulin concentration and disease evolution.

  2000cited by this paper
• Alteration of tumor necrosis factor-alpha T-cell homeostasis following potent antiretroviral therapy: contribution to the development of human immunodeficiency virus-associated lipodystrophy syndrome.

  2000cited by this paper
• Human Immunodeficiency Virus Type 1 Vpr Induces Apoptosis through Caspase Activation

  2000cited by this paper
• Protease inhibitors stimulate hematopoiesis and decrease apoptosis and ICE expression in CD34(+) cells.

  2000cited by this paper
• HIV protease inhibitors restore impaired T-cell proliferative response in vivo and in vitro: a viral-suppression-independent mechanism.

  2000cited by this paper
• Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4+ and CD8+ T cell turnover in HIV-infected patients.

  2000cited by this paper
• T-cell progenitor function during progressive human immunodeficiency virus-1 infection and after antiretroviral therapy.

  2000cited by this paper
• Virus and target cell evolution in human immunodeficiency virus type 1 infection

  2000cited by this paper
• Envelope Glycoprotein Determinants of Increased Fusogenicity in a Pathogenic Simian-Human Immunodeficiency Virus (SHIV-KB9) Passaged In Vivo

  2000cited by this paper
• Alteration of tumor necrosis factor–α T-cell homeostasis following potent antiretroviral therapy: contribution to the development of human immunodeficiency virus–associated lipodystrophy syndrome

  2000cited by this paper
• Apoptosis and the CD95 system in HIV disease: impact of highly active anti-retroviral therapy (HAART).

  1999cited by this paper
• Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans

  1999cited by this paper
• Human immunodeficiency virus type 1 protease inhibitor modulates activation of peripheral blood CD4(+) T cells and decreases their susceptibility to apoptosis in vitro and in vivo.

  1999cited by this paper
• Dynamic correlation of apoptosis and immune activation during treatment of HIV infection

  1999cited by this paper
• Vpu Increases Susceptibility of Human Immunodeficiency Virus Type 1-Infected Cells to Fas Killing

  1999cited by this paper
• Activation, survival and apoptosis of CD45RO+ and CD45RO− T cells of human immunodeficiency virus‐infected individuals: effects of interleukin‐15 and comparison with interleukin‐2

  1999cited by this paper
• Enhanced survival and potent expansion of the natural killer cell population of HIV-infected individuals by exogenous interleukin-15.

  1999cited by this paper
• Human Immunodeficiency Virus Type 1 Tat Induces Apoptosis and Increases Sensitivity to Apoptotic Signals by Up-Regulating FLICE/Caspase-8

  1999cited by this paper
• Interleukin-15 is a potent survival factor in the prevention of spontaneous but not CD95-induced apoptosis in CD4 and CD8 T lymphocytes of HIV-infected individuals. Correlation with its ability to increase BCL-2 expression

  1999cited by this paper
• Caspase-3-dependent Cleavage of Bcl-2 Promotes Release of Cytochrome c *

  1999cited by this paper
• A novel mechanism of CD4 lymphocyte depletion involves effects of HIV on resting lymphocytes: induction of lymph node homing and apoptosis upon secondary signaling through homing receptors.

  1999cited by this paper
• Human immunodeficiency virus type 1 Nef protein sensitizes CD4(+) T lymphoid cells to apoptosis via functional upregulation of the CD95/CD95 ligand pathway.

  1999cited by this paper
• Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes.

  1999cited by this paper
• Programmed Cell Death as a Mechanism of CD4 and CD8 T Cell Deletion in AIDS: Molecular Control and Effect of Highly Active Anti‐retroviral Therapy

  1999cited by this paper
• Upregulation of Fas ligand secretion in non-lymphopenic stages of HIV-1 infection.

  1998cited by this paper
• The role of interleukin-converting enzyme in Fas-mediated apoptosis in HIV-1 infection.

  1998cited by this paper
• Tumor necrosis factor beta and soluble APO-1/Fas independently predict progression to AIDS in HIV-seropositive patients.

  1998cited by this paper
• Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA.

  1998cited by this paper
• All-trans retinoic acid inhibition of anti-CD3-induced T cell apoptosis in human immunodeficiency virus infection mostly concerns CD4 T lymphocytes and is mediated via regulation of CD95 ligand expression.

  1998cited by this paper
• Supraoptimal Peptide–Major Histocompatibility Complex Causes a Decrease in Bcl-2 Levels and Allows Tumor Necrosis Factor α Receptor II–mediated Apoptosis of Cytotoxic T Lymphocytes

  1998cited by this paper
• Tumor Necrosis Factor β and Soluble APO-1/Fas Independently Predict Progression to AIDS in HIV-Seropositive Patients

  1998cited by this paper
• Distinct Mechanisms Trigger Apoptosis in Human Immunodeficiency Virus Type 1-Infected and in Uninfected Bystander T Lymphocytes

  1998cited by this paper
• CXCR4 and CD4 mediate a rapid CD95-independent cell death in CD4(+) T cells.

  1998cited by this paper
• Loss of CD4+ T Cells in Human Immunodeficiency Virus Type 1-Infected Chimpanzees Is Associated with Increased Lymphocyte Apoptosis

  1998cited by this paper
• A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors

  1998cited by this paper
• Diminished spontaneous apoptosis in lymphocytes from human immunodeficiency virus-infected long-term nonprogressors.

  1998cited by this paper
• HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes

  1998cited by this paper
• Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4

  1998cited by this paper
• Changes in thymic function with age and during the treatment of HIV infection

  1998cited by this paper
• TRAIL/Apo‐2‐ligand‐induced apoptosis in human T cells

  1998cited by this paper

• Peculiar Cat with Many Lives: PUMA in Viral Infections

  2026cites this paper
• Apoptosis and FoxO signaling axis form the core antiviral defense in mud crab (Scylla paramamosain) against MCRV

  2026cites this paper
• The Interplay Between Viral Infection and Cell Death: A Ping-Pong Effect

  2025cites this paper
• Review of research progress on detection methods for CD4+ T lymphocytes infected with HIV

  2025cites this paper
• HIV immune evasin Nef enhances allogeneic CAR T cell potency

  2025cites this paper
• Intracellular ISG-virus interactions determine viral infection severity and persistence.

  2025cites this paper
• Propolis consumption by asymptomatic HIV-individuals: Better redox state? A prospective, randomized, double-blind, placebo-controlled trial.

  2023cites this paper
• Cellular Targets of HIV-1 Protease: Just the Tip of the Iceberg?

  2023cites this paper
• Mapping the interplay between NK cells and HIV: therapeutic implications

  2023cites this paper
• SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction

  2020cites this paper
• Associations between recent thymic emigrants and CD4+ T-cell recovery after short-term antiretroviral therapy initiation

  2019cites this paper
• Histone methyltransferase NSD2 regulates apoptosis and chemosensitivity in osteosarcoma

  2019cites this paper
• Mass cytometry identifies distinct CD4+ T cell clusters distinguishing HIV-1-infected patients according to antiretroviral therapy initiation.

  2019cites this paper
• Natural Infection with Rabies Virus: A Histopathological and Immunohistochemical Study of Human Brains

  2019cites this paper
• Growth scaling for the early dynamics of HIV/AIDS epidemics in Brazil and the influence of socio-demographic factors.

  2018cites this paper
• Mini Review - Epigenetics: Quest for no-escape to HIV, a persistent pathogen.

  2018cites this paper
• Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease

  2018cites this paper
• Ostreid Herpesvirus-1 Infects Specific Hemocytes in Ark Clam, Scapharca broughtonii

  2018cites this paper
• Prediction of HIV-1 and HIV-2 proteins by using Chou’s pseudo amino acid compositions and different classifiers

  2018cites this paper
• The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4+ T cell apoptosis.

  2017cites this paper
• RNAa Induced by TATA Box-Targeting MicroRNAs.

  2017cites this paper
• The levels of DNGR-1 and its ligand-bearing cells were altered after human and simian immunodeficiency virus infection

  2017cites this paper
• Wasserdeprivation und Tyrosinase als Trigger des erythrozytären programmierten Zelltodes

  2017cites this paper
• The Antiviral Immune Response and Its Impact on the HIV-1 Reservoir.

  2017cites this paper
• HIV-1 Tat potently stabilises Mdm2 and enhances viral replication

  2017cites this paper
• On the Potential for Multiscale Oscillatory Behavior in HIV

  2017cites this paper
• Alarmins and central nervous system inflammation in HIV‐associated neurological disorders

  2017cites this paper
• Mitochondria as a Favourite Organelle for Invading Viruses

  2016cites this paper
• A Novel Generation of Lentiviral Vectors for Gene Therapy

  2016cites this paper
• Subversion of the Immune Response by Rabies Virus

  2016cites this paper
• HMGB1 Is Involved in IFN-α Production and TRAIL Expression by HIV-1-Exposed Plasmacytoid Dendritic Cells: Impact of the Crosstalk with NK Cells

  2016cites this paper
• Design and Synthesis of Peptide and Peptidomimetics Involved in Antiretroviral and Anticancer Therapies

  2016cites this paper
• Interactions of Opioids and HIV Infection in the Pathogenesis of Chronic Pain

  2016cites this paper
• Analyse du profil d'expression de la protéine pro-apoptotique Dap-3 dans les vésicules extracellulaires produites dans le contexte de l'infection au VIH-1

  2016cites this paper
• EAR, NOSE AND THROAT-HEAD AND NECK MANIFESTATIONS AND EFFECT OF ANTIRETROVIRAL THERAPY IN HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN CHILDREN

  2016cites this paper
• HIV-1 Infection-Induced Suppression of the Let-7i/IL-2 Axis Contributes to CD4+ T Cell Death

  2016cites this paper
• Early IFN type I response: Learning from microbial evasion strategies

  2015cites this paper
• Evaluation of type I interferon responses to HIV infection in CD4+ T cells

  2015cites this paper
• Terminal Differentiation of CD56dimCD16+ Natural Killer Cells Is Associated with Increase in Natural Killer Cell Frequencies After Antiretroviral Treatment in HIV-1 Infection

  2015cites this paper
• The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation

  2015cites this paper
• A review of in silico approaches for analysis and prediction of HIV-1-human protein-protein interactions

  2015cites this paper
• Dissecting mechanisms underlying increased TLR7-mediated IFNα production in pDCs in physiological and pathophysiological settings : between sex differences and HIV-1-HCV co-infection

  2015cites this paper
• 73 – Human Immunodeficiency Virus and Allergic Disease

  2014cites this paper
• HIV-1 Vpu Accessory Protein Induces Caspase-mediated Cleavage of IRF3 Transcription Factor*

  2014cites this paper
• Characterization of HIV specific T cell responses during acute and early HIV-1 subtype C infection

  2014cites this paper
• Dendritic Cell Dysfunction : A Key to HIV Spread and Persistence

  2014cites this paper
• HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cells

  2014cites this paper
• Capacité des protéines du VIH Tat et Nef et des inhibiteurs de la protéase virale à induire une sénescence des cellules souches mésenchymateuses de la moelle osseuse et à inhiber leur différenciation ostéoblastique

  2014cites this paper
• Elevated CD57 and CD95 expressions are associated with lower numbers of CD4⁺ recent thymic emigrants in HIV-1 infected immune responders following antiretroviral treatment.

  2014cites this paper
• The Majority of CD4+ T-Cell Depletion during Acute Simian-Human Immunodeficiency Virus SHIV89.6P Infection Occurs in Uninfected Cells

  2014cites this paper
• MicroRNAs and HIV-1 infection: antiviral activities and beyond.

  2014cites this paper
• Effect of Hepatitis C Infection on HIV-Induced Apoptosis

  2013cites this paper
• impaired proliferative capacity in acute and chronic SIVmac251 infection SIV-specific CD8+T-cells express high levels of PD1 and cytokines but have

  2013cites this paper
• HIV-specific CD8+ T cells Increased mitochondrial mass characterizes the survival defect of

  2013cites this paper
• Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling

  2013cites this paper
• Neuronal Apoptosis in HIV-1-Associated Central Nervous Diseases and Neuropathic Pain

  2013cites this paper
• Foxo 3 a : an integrator of immune dysfunction during HIV infection

  2013cites this paper
• Lentiviral Gene Therapy Vectors: Challenges and Future Directions

  2013cites this paper
• Mitochondrial function and apoptosis of peripheral mononuclear cells (PBMCs) in the HIV infected patients.

  2013cites this paper
• Université de Montréal-Thèse numérique

  2013cites this paper
• Präklinische Evaluation von Titanocenverbindungen als potentielle Zytostatika

  2013cites this paper
• Directly Infected Resting CD4+T Cells Can Produce HIV Gag without Spreading Infection in a Model of HIV Latency

  2012cites this paper
• HIV-1 subtype B and C GP120-mediated apoptosis of bystander CD4+ T lymphocytes

  2012cites this paper
• GO for Integration of Expression Data

  2012cites this paper
• Citopaticitat de la glicoproteïna de l’embolcall del VIH-1. Mecanismes directes i indirectes i implicació en la progressió clínica.

  2012cites this paper
• Foxo3a: an integrator of immune dysfunction during HIV infection.

  2012cites this paper
• The HR2 polymorphism N140I in the HIV-1 gp41 combined with the HR1 V38A mutation is associated with a less cytopathic phenotype

  2012cites this paper
• A Monoclonal Antibody Directed against a Conformational Epitope of the HIV-1 Trans-activator (Tat) Protein Neutralizes Cross-clade

  2012cites this paper
• Clinical implications of immune recovery during antiretroviral treatment for HIV infection

  2012cites this paper
• IFN-α and TRAIL: a double edge sword in HIV-1 disease?

  2012cites this paper
• Gene Array Studies in HIV-1 Infection

  2012cites this paper
• FasL and TRAIL signaling in the skin during cutaneous leishmaniasis - implications for tissue immunopathology and infectious control

  2012cites this paper
• An HIVgp41 vaccine protects CD4 central memory T cells in SHIV-infected macaques.

  2012cites this paper
• Prediction of host-virus interaction networks

  2012cites this paper
• Host genetic effects on HIV-1 replication in macrophages

  2011cites this paper
• Natural killer cells, dendritic cells, and the alarmin high-mobility group box 1 protein: a dangerous trio in HIV-1 infection?

  2011cites this paper
• Influenza A and Flavivirus Manipulation of Cell Death

  2011cites this paper
• CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis

  2011cites this paper
• Survival and proliferation of CD28- T cells during HIV-1 infection relate to the amplitude of viral replication.

  2011cites this paper
• Réponse innée des cellules dendritiques plasmacytoides lors de stimulations rétrovirales (HTLV-1, VIH-1)

  2011cites this paper
• HMGB1, an alarmin promoting HIV dissemination and latency in dendritic cells

  2011cites this paper
• Role of IL-7 in immune activation during HIV-1 infection

  2011influential citation
• The suppression of immune activation during enfuvirtide‐based salvage therapy is associated with reduced CCR5 expression and decreased concentrations of circulating interleukin‐12 and IP‐10 during 48 weeks of longitudinal follow‐up

  2011cites this paper
• The HIV-1-Specific Protein Casp8p41 Induces Death of Infected Cells through Bax/Bak

  2011cites this paper
• HIV envelope-mediated, CCR5/α4β7-dependent killing of CD4-negative γδ T cells which are lost during progression to AIDS.

  2011cites this paper
• Targeting the HIV entry, assembly and release pathways for anti-HIV gene therapy.

  2011cites this paper
• IL-7 Promotes CD95-Induced Apoptosis in B Cells via the IFN-γ/STAT1 Pathway

  2011cites this paper
• Genome-Wide Association Study Identifies Single Nucleotide Polymorphism in DYRK1A Associated with Replication of HIV-1 in Monocyte-Derived Macrophages

  2011cites this paper
• Intracellular Events and Cell Fate in Filovirus Infection

  2011cites this paper
• Production of Retroviral and Lentiviral Gene Therapy Vectors: Challenges in the Manufacturing of Lipid Enveloped Virus

  2011cites this paper
• Impact of γ‐chain cytokines on T cell homeostasis in HIV‐1 infection: therapeutic implications

  2010cites this paper
• Inability of Plasmacytoid Dendritic Cells To Directly Lyse HIV-Infected Autologous CD4 (cid:1) T Cells despite Induction of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (cid:1)

  2010cites this paper
• Selective killing of human immunodeficiency virus infected cells by non-nucleoside reverse transcriptase inhibitor-induced activation of HIV protease

  2010cites this paper
• Proteomic analysis identifies prohibitin down-regulation as a crucial event in the mitochondrial damage observed in HIV-infected patients

  2010cites this paper
• Caveolin-1 Modulates HIV-1 Envelope-Induced Bystander Apoptosis through gp41

  2010cites this paper
• Intracellular accumulation of cell cycle regulatory proteins and nucleolin re-localization are associated with pre-lethal ultrastructural lesions in circulating T lymphocytes: The HIV-induced cell cycle dysregulation revisited

  2010cites this paper
• Structural similarity-based predictions of protein interactions between HIV-1 and Homo sapiens

  2010cites this paper
• Effectiveness of a ‘hunter’ virus in controlling human immunodeficiency virus type 1 infection

  2010influential citation
• The cell death regulator GRIM-19 is involved in HIV-1 induced T-cell apoptosis

  2010cites this paper
• Kinoids: a family of immunogens for active anticytokine immunotherapy applied to autoimmune diseases and cancer.

  2010cites this paper