Liver as the primary site of erythropoietin formation in the fetus.

No abstract is available for this paper.

• Publication year

  1977

• Venue

  Journal of Laboratory and Clinical Medicine

• Publication date

  1977-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  PMID 839121
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Evidence for a physiologic role of erythropoietin in fetal erythropoiesis.

  1974cited by this paper
• Erythropoietin production in the fetus: role of the kidney and maternal anemia.

  1974cited by this paper
• Hepatic erythropoietin production in the lead-poisoned rat.

  1974cited by this paper
• Extrarenal Sites of Erythrogenin Production 1

  1973cited by this paper
• Erythropoietin production in nephrectomized rats: possible role of the renal erythropoietic factor.

  1972cited by this paper
• The liver as a source of extrarenal erythropoietin production.

  1972cited by this paper
• Immunologic aspects of the biogenesis of erythropoietin.

  1970cited by this paper
• Erythropoietin production in the fetal lamb.

  1969cited by this paper
• ANDROGEN ACTIONS ON ERYTHROPOIESIS *

  1968cited by this paper
• REGULATION OF ERYTHROPOIESIS. XV. NEONATAL ERYTHROPOIESIS AND THE EFFECT OF NEPHRECTOMY.

  1964cited by this paper
• The production of an erythropoietic factor by the in situ perfused kidney.

  1961cited by this paper
• Role of the Kidney in Erythropoiesis

  1957cited by this paper
• Presence of Plasma Erythropoietin in Hypoxic Rats with or without Kidney(s) and/or Spleen

  1957cited by this paper

• Detection of a Distinct Erythropoietin (EPO) Profile After Isoelectric Focusing in Patients With Familial Erythrocytosis.

  2026cites this paper
• Middle Cerebral Artery Peak Systolic Velocity in Fetuses With Transposition of the Great Arteries

  2025cites this paper
• Novel roles of cardiac-derived erythropoietin in cardiac development and function.

  2024cites this paper
• Erythropoietin and Skeletal Cells CrossTalks in Physiology and Disease

  2023cites this paper
• In Vitro Human Haematopoietic Stem Cell Expansion and Differentiation

  2023cites this paper
• Neonatal administration of erythropoietin attenuates cognitive deficits in adult rats following placental insufficiency

  2021cites this paper
• Systematic Review of Erythropoietin (EPO) for Neuroprotection in Human Studies

  2021cites this paper
• Pleiotropic effects of Erythropoietin. Influence of Erythropoietin on processes of mesenchymal stem cells differentiation

  2019cites this paper
• Erythropoietin Prevents Anemia and Transfusions in Extremely Premature Lambs Supported by an EXTrauterine Environment for Neonatal Development (EXTEND)

  2019cites this paper
• Time to reconsider extended erythropoietin treatment for infantile traumatic brain injury?

  2019cites this paper
• Erythropoietin-Mediated Regulation of Central Respiratory Command.

  2017cites this paper
• Endogenous Erythropoietin.

  2017cites this paper
• Studies on tissue protective cytokines in remyelination and regenerative medicine

  2016cites this paper
• Pharmacological modulation of inflammation associated with inflammatory bowel disease : - study in an animal model

  2016cites this paper
• The pathophysiology of retinopathy of prematurity: an update of previous and recent knowledge

  2014cites this paper
• Selective expression of transgene using hypoxia-inducible trans-splicing group I intron ribozyme.

  2014cites this paper
• The potential of erythropoietin to treat asphyxia in newborns

  2014cites this paper
• Population pharmacodynamic analysis of erythropoiesis in preterm infants for determining the anemia treatment potential of erythropoietin.

  2013cites this paper
• Enhanced erythropoiesis in mice exposed to low environmental temperature

  2013cites this paper
• Erythropoietin levels in premature neonates in relation to red blood cell transfusions

  2013cites this paper
• Stem Cells and Progenitors in Liver Development

  2013cites this paper
• Erythropoietin and Diabetic Retinopathy

  2013cites this paper
• Analysis about the influence on the fetus infected with parvovirus B19 using amniotic erythropoietin and troponin-T

  2013cites this paper
• Human erythropoietin gene delivery using an arginine-grafted bioreducible polymer system.

  2012cites this paper
• cDNA cloning and expression of erythropoietin in the plateau zokor (Myospalax baileyi) from the Qinghai-Tibet Plateau

  2012cites this paper
• Predicted structural change in erythropoietin of plateau zokors--adaptation to high altitude.

  2012cites this paper
• Population pharmacokinetic / pharmacodynamic analysis of erythropoiesis kinetics

  2012cites this paper
• The Protective Role of Erythropoietin in the Developing Brain

  2012cites this paper
• Erythropoietin produced by the retina: its role in physiology and diabetic retinopathy

  2012cites this paper
• Preterm Birth - Mother and Child

  2012cites this paper
• Involvement of placental/umbilical cord blood acid–base status and gas values on the radiosensitivity of human fetal/neonatal hematopoietic stem/progenitor cells

  2012cites this paper
• Erythropoietin in neonatal brain protection: the past, the present and the future.

  2011cites this paper
• EVALUATION OF PH/BUFFERING CONDITIONS EFFECT ON THE OPTIMIZATION OF RECOMBINANT HUMAN ERYTHROPOIETIN EXPRESSION IN THE METHYLOTROPHIC YEAST, PICHIA PASTORIS

  2011cites this paper
• Der Tumorsuppressor Wt1 aktiviert die Transkription des Erythropoietinrezeptors in hämatopoietischen Vorläuferzellen

  2011cites this paper
• Etude des mécanismes cellulaires et moléculaires de l'inhibition de l'érythropoïèse par la cytokine pro-inflammatoire Tumor necrosis factor (TNF)-alpha

  2011cites this paper
• Enhanced recombinant human erythropoietin production by Pichia pastoris in methanol fed-batch/sorbitol batch fermentation through pH optimization

  2011cites this paper
• Erytropoetyna ó alternatywne leczenie niedokrwistoúci u niemowl"t Erythropoietin ó the alternative treatment of anemia in infants

  2011cites this paper
• Tissue Protection and Regeneration Aided by Erythropoietin and Erythropoietin-derived Peptides

  2011cites this paper
• Erythropoietin as a neuroprotective agent.

  2011cites this paper
• Erythropoietin, erythropoiesis and beyond.

  2011cites this paper
• Anemia and Progression of Chronic Kidney Disease

  2011cites this paper
• Erythropoietin as a Neuroprotective Agent

  2011cites this paper
• Renoprotective effect of erythropoietin against ischaemia-reperfusion injury in a non-human primate model.

  2011cites this paper
• Response to chronic intermittent hypoxia in blood system of Mandarin vole (Lasiopodomys mandarinus).

  2010cites this paper
• Landmark advances in the development of erythropoietin

  2010cites this paper
• UPSTREAM PATHWAYS REGULATING ERYTHROPOIETIN GENE EXPRESSION IN THE LIVER DURING ACUTE PHASE RESPONSE: A CENTRAL ROLE FOR IL-6.

  2010cites this paper
• Quelle place reste-t-il pour l’érythropoïétine en néonatalogie ?

  2009cites this paper
• Growth factors in ischemic stroke

  2009cites this paper
• Erythropoietin and renoprotection

  2009cites this paper
• Is there a role for erythropoietin in neonatal medicine?

  2008cites this paper
• Alterations in Methylation of the Erythropoietin Gene During Human Fetal Development

  2008cites this paper
• Physiology of erythropoiesis

  2008cites this paper
• The non‐haematopoietic biological effects of erythropoietin

  2008cites this paper
• Characterization of the Sleeping Beauty transposon system for gene therapy applications

  2008cites this paper
• Increased Fetal Plasma and Amniotic Fluid Erythropoietin Concentrations: Markers of Intrauterine Hypoxia

  2008cites this paper
• Hétérérogénéité génétique de la polyglobulie

  2008cites this paper
• Therapeutic strategy of erythropoietin in neurological disorders.

  2008cites this paper
• Human erythropoietin induces lung failure and erythrocytosis in transgenic mice.

  2007cites this paper
• The role of erythropoietin in central and peripheral nerve injury.

  2007cites this paper
• Study of hepatocytes using RNA interference

  2007cites this paper
• zur Erlangung des Doktorgrades

  2007cites this paper
• Production of recombinant human erythropoietin from Pichia pastoris and its structural analysis

  2007cites this paper
• Wilms tumor suppressor, Wt1, is a transcriptional activator of the erythropoietin gene.

  2006cites this paper
• Erythropoietin-producing cells in the liver of ICR-derived glomerulonephritis (ICGN) mice.

  2006cites this paper
• Érythropoïèse et bronchopneumopathie chronique obstructive

  2006cites this paper
• Studies on the specificities of in vivo and in vitro bioassays used in the potency determination of therapeutic erythropoietin

  2006cites this paper
• Erythropoietin receptor spliced forms differentially expressed in blind subterranean mole rats

  2005cites this paper
• Human growth hormone and insulin-like growth factor-I inhibit erythropoietin secretion from the kidneys of adult rats.

  2005cites this paper
• Erythropoietin: the story of hypoxia and a finely regulated hematopoietic hormone.

  2005cites this paper
• AVALIAÇÃO DA POTÊNCIA BIOLÓGICA DA ERITROPOETINA HUMANA RECOMBINANTE EM PRODUTOS FARMACÊUTICOS: Estudo comparativo entre as linhagens de camundongos B6D2F1 e Swiss Webster.

  2004cites this paper
• Hepatic Erythropoietin Gene Regulation by GATA-4*

  2004cites this paper
• A cross-talk between hypoxia and TGF-beta orchestrates erythropoietin gene regulation through SP1 and Smads.

  2004cites this paper
• Combinación del sacarato férrico y eritropoyetina frente a sulfato ferroso. Sus efectos sobre el binomio madre-feto

  2004cites this paper
• Anemia with chronic renal disorder and disrupted metabolism of erythropoietin in ICR-derived glomerulonephritis (ICGN) mice.

  2004cites this paper
• Hypoxic stress tolerance of the blind subterranean mole rat: expression of erythropoietin and hypoxia-inducible factor 1 alpha.

  2004cites this paper
• Erythropoietin: Physiology and Pharmacology Update 2

  2003cites this paper
• Prenatal smoke exposure alters growth in limb proportions and head shape in the midgestation human fetus

  2003cites this paper
• Autocrine stimulation by erythropoietin in transgenic mice results in erythroid proliferation without neoplastic transformation.

  2003cites this paper
• Types of Programmed Cell Death: Two Variants Expressed by Neonatal Murine Hepatocytes

  2003cites this paper
• CHAPTER 7 – Erythropoietin

  2003cites this paper
• ENU mutagenesis for the generation of mouse mutants and identification of genes involved in hematolymphoid development

  2003cites this paper
• Renal and placental secretion of erythropoietin during anemia or hypoxia in the ovine fetus.

  2003cites this paper
• Erythropoietin and hypoxia inducible factor‐1 expression in the mid‐trimester human fetus

  2002cites this paper
• Erythropoieti nProtect sNeuron sAgainst Chemica lHypoxi aan dCerebra lIschemic Injur yb yUp-Regulatin gBcl-x L Expression

  2002cites this paper
• Does administration of recombinant human erythropoietin attenuate the increase of S-100 protein observed in cerebrospinal fluid after experimental subarachnoid hemorrhage?

  2002cites this paper
• Developmental stage-specific expression of the alpha and beta subunits of the HIF-1 protein in the mouse and human fetus.

  2002cites this paper
• Erythropoietin protects neurons against chemical hypoxia and cerebral ischemic injury by up‐regulating Bcl‐xL expression

  2002cites this paper
• Management of the Anemia of Prematurity Using Human Recombinant Erythropoietin

  2002cites this paper
• Human Recombinant Erythropoietin in the Prevention and Treatment of Anemia of Prematurity

  2002cites this paper
• Ontogeny of erythropoietin mRNA expression in liver, kidneys and testes of the foetal and the neonatal pig.

  2002cites this paper
• Placental expression of erythropoietin mRNA, protein and receptor in sheep.

  2001cites this paper
• Erythropoietin responses to progressive blood loss over 10 days in the ovine fetus.

  2001cites this paper
• Stimulation of GATA‐2 as a mechanism of hydrogen peroxide suppression in hypoxia‐induced erythropoietin gene expression

  2001cites this paper
• Serum erythropoietin levels in ovarian cancer patients receiving chemotherapy.

  2001cites this paper
• N(G)-monomethyl-L-arginine inhibits erythropoietin gene expression by stimulating GATA-2.

  2000cites this paper
• DNA methylation represses the expression of the human erythropoietin gene by two different mechanisms.

  2000cites this paper
• The use of erythropoietin in neonates.

  2000cites this paper
• Zinc Induces the Accumulation of Hypoxia-Inducible Factor (HIF)-1α, but Inhibits the Nuclear Translocation of HIF-1β, Causing HIF-1 Inactivation

  2000cites this paper
• Zinc induces the accumulation of hypoxia-inducible factor (HIF)-1alpha, but inhibits the nuclear translocation of HIF-1beta, causing HIF-1 inactivation.

  2000cites this paper
• Neurons and astrocytes express EPO mRNA: Oxygen‐sensing mechanisms that involve the redox‐state of the brain

  2000cites this paper