Transcript and metabolite profiling during cold acclimation of Arabidopsis reveals an intricate relationship of cold-regulated gene expression with modifications in metabolite content.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  The Plant Journal

• Publication date

  2007-04-25

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1111/J.1365-313X.2007.03100.XPMID 17461790
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A nuclear gene encoding mitochondrial Delta-pyrroline-5-carboxylate dehydrogenase and its potential role in protection from proline toxicity.

  2008cited by this paper
• Water and salinity stress in grapevines: early and late changes in transcript and metabolite profiles

  2007cited by this paper
• Profiling lipid changes in plant response to low temperatures

  2006cited by this paper
• Carbon partitioning and export in transgenic Arabidopsis thaliana with altered capacity for sucrose synthesis grown at low temperature: a role for metabolite transporters.

  2006cited by this paper
• Unraveling abiotic stress tolerance mechanisms--getting genomics going.

  2006cited by this paper
• Proteomics and low-temperature studies : bridging the gap between gene expression and metabolism

  2006cited by this paper
• Natural Genetic Variation of Freezing Tolerance in Arabidopsis[W][OA]

  2006cited by this paper
• Non-linear PCA: a missing data approach

  2005cited by this paper
• Endogenous siRNAs Derived from a Pair of Natural cis-Antisense Transcripts Regulate Salt Tolerance in Arabidopsis

  2005cited by this paper
• Metabolomics, genomics, proteomics, and the identification of enzymes and their substrates and products.

  2005cited by this paper
• Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor.

  2005cited by this paper
• Integrating genomics and metabolomics for engineering plant metabolic pathways.

  2005cited by this paper
• Elucidation of Gene-to-Gene and Metabolite-to-Gene Networks in Arabidopsis by Integration of Metabolomics and Transcriptomics*

  2005cited by this paper
• The meaning of systems biology.

  2005cited by this paper
• A global reorganization of the metabolome in Arabidopsis during cold acclimation is revealed by metabolic fingerprinting

  2005cited by this paper
• Diurnal Changes in the Transcriptome Encoding Enzymes of Starch Metabolism Provide Evidence for Both Transcriptional and Posttranscriptional Regulation of Starch Metabolism in Arabidopsis Leaves1

  2004cited by this paper
• A prominent role for the CBF cold response pathway in configuring the low-temperature metabolome of Arabidopsis.

  2004cited by this paper
• Counting the cost of a cold-blooded life: metabolomics of cold acclimation.

  2004cited by this paper
• GABA in plants: just a metabolite?

  2004cited by this paper
• Connecting genes to metabolites by a systems biology approach.

  2004cited by this paper
• Exploring the Temperature-Stress Metabolome of Arabidopsis1[w]

  2004cited by this paper
• myo-Inositol and sucrose concentrations affect the accumulation of raffinose family oligosaccharides in seeds.

  2004cited by this paper
• Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana.

  2004cited by this paper
• Heterosis in the freezing tolerance of crosses between two Arabidopsis thaliana accessions (Columbia-0 and C24) that show differences in non-acclimated and acclimated freezing tolerance.

  2004cited by this paper
• Roles of the CBF2 and ZAT12 transcription factors in configuring the low temperature transcriptome of Arabidopsis.

  2004cited by this paper
• Physiological and Molecular Assessment of Altered Expression of Hsc70-1 in Arabidopsis. Evidence for Pleiotropic Consequences1

  2003cited by this paper
• Role of the Arabidopsis Glucose Sensor HXK1 in Nutrient, Light, and Hormonal Signaling

  2003cited by this paper
• Acquired tolerance to temperature extremes.

  2003cited by this paper
• Insights into metabolism obtained from microarray analysis.

  2003cited by this paper
• Regulatory network of gene expression in the drought and cold stress responses.

  2003cited by this paper
• Cell signalling and gene regulation: global analyses of signal transduction and gene expression profiles.

  2003cited by this paper
• Mitochondrial succinic-semialdehyde dehydrogenase of the γ-aminobutyrate shunt is required to restrict levels of reactive oxygen intermediates in plants

  2003cited by this paper
• Freezing Sensitivity in the sfr4 Mutant of Arabidopsis Is Due to Low Sugar Content and Is Manifested by Loss of Osmotic Responsiveness1

  2003cited by this paper
• Transcriptome Changes for Arabidopsis in Response to Salt, Osmotic, and Cold Stress1,212

  2002cited by this paper
• Arabidopsis Transcriptome Profiling Indicates That Multiple Regulatory Pathways Are Activated during Cold Acclimation in Addition to the CBF Cold Response Pathway Online version contains Web-only data. Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1

  2002cited by this paper
• A plant for all seasons: alterations in photosynthetic carbon metabolism during cold acclimation in Arabidopsis.

  2002cited by this paper
• Important roles of drought- and cold-inducible genes for galactinol synthase in stress tolerance in Arabidopsis thaliana.

  2002cited by this paper
• Monitoring the expression profiles of 7000 Arabidopsis genes under drought, cold and high-salinity stresses using a full-length cDNA microarray.

  2002cited by this paper
• Functional expression of a cDNA encoding pea (Pisum sativum L.) raffinose synthase, partial purification of the enzyme from maturing seeds, and steady-state kinetic analysis of raffinose synthesis

  2002cited by this paper
• Sugar Sensing and Signaling in Plants Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.010455.

  2002cited by this paper
• Transcriptome meets metabolome: hierarchical and metabolic regulation of the glycolytic pathway

  2001cited by this paper
• The 5' untranslated region of the At-P5R gene is involved in both transcriptional and post-transcriptional regulation.

  2001cited by this paper
• Metabolite profiling for plant functional genomics

  2000cited by this paper
• Oscillation and regulation of proline content by P5CS and ProDH gene expressions in the light/dark cycles in Arabidopsis thaliana L.

  2000cited by this paper
• Overexpression of the Arabidopsis CBF3 transcriptional activator mimics multiple biochemical changes associated with cold acclimation.

  2000cited by this paper
• Removal of feedback inhibition of delta(1)-pyrroline-5-carboxylate synthetase results in increased proline accumulation and protection of plants from osmotic stress.

  2000cited by this paper
• Regulation of a plant SNF1-related protein kinase by glucose-6-phosphate.

  2000cited by this paper
• Cold-induced freezing tolerance in Arabidopsis.

  1999cited by this paper
• Molecular responses of plants to cold shock and cold acclimation.

  1999cited by this paper
• PLANT COLD ACCLIMATION: Freezing Tolerance Genes and Regulatory Mechanisms.

  1999cited by this paper
• The Metabolism and Functions of [gamma]-Aminobutyric Acid.

  1999cited by this paper
• Eskimo1 mutants of Arabidopsis are constitutively freezing-tolerant.

  1998cited by this paper
• Differential expression of two P5CS genes controlling proline accumulation during salt-stress requires ABA and is regulated by ABA1, ABI1 and AXR2 in Arabidopsis.

  1997cited by this paper
• The Metabolism and Functions of [gamma]-Aminobutyric Acid

  1997cited by this paper
• A nuclear gene encoding mitochondrial proline dehydrogenase, an enzyme involved in proline metabolism, is upregulated by proline but downregulated by dehydration in Arabidopsis.

  1996cited by this paper
• Reciprocal regulation of Δ1-pyrroline-5-carboxylate synthetase and proline dehydrogenase genes controls proline levels during and after osmotic stress in plants

  1996cited by this paper
• Correlation between the induction of a gene for delta 1-pyrroline-5-carboxylate synthetase and the accumulation of proline in Arabidopsis thaliana under osmotic stress.

  1995cited by this paper
• Osmoregulation of a Pyrroline-5-Carboxylate Reductase Gene in Arabidopsis thaliana

  1993cited by this paper
• Sucrose phosphate synthase and sucrose accumulation at low temperature.

  1992cited by this paper
• A bifunctional enzyme (delta 1-pyrroline-5-carboxylate synthetase) catalyzes the first two steps in proline biosynthesis in plants.

  1992cited by this paper
• Cold Acclimation and Freezing Stress Tolerance: Role of Protein Metabolism

  1990cited by this paper
• The mechanism of cryoprotection of proteins by solutes.

  1988cited by this paper
• Stabilization of lipid bilayer vesicles by sucrose during freezing.

  1986cited by this paper
• Living with water stress: evolution of osmolyte systems.

  1982cited by this paper
• Stabilization and inactivation of biological membranes during freezing in the presence of amino acids.

  1971cited by this paper

• Interaction of 4-Aminobutyrate (GABA) with the Tricarboxylic Acid Cycle in Plants Under Salinity Stress

  2026cites this paper
• Integrated physiological and transcriptomic analysis reveals novel key genes underlying cold tolerance in Nicotiana tabacum

  2026influential citation
• Effects of Ca2+ signaling inhibition on cold acclimation in winter rapeseed

  2025cites this paper
• Synergistic Interaction Between VyMYB24 from Chinese Wild Grape Vitis yeshanensis and Cytokinin Enhances Cold Tolerance in Transgenic Tobacco

  2025cites this paper
• The Vacuolar Inositol Transporter BvINT1;1 Contributes to Raffinose Biosynthesis and Reactive Oxygen Species Scavenging During Cold Stress in Sugar Beet

  2025cites this paper
• Integrative Profiling of Phytohormones, Metabolomics, and Transcriptomics Reveals Key Regulators of Cold Tolerance in Cucumber Leaves

  2025cites this paper
• Recovery Dynamics of Photosynthetic Performance and Antioxidant Defense in Resurrection Plants Ramonda serbica and Ramonda nathaliae After Freezing-Induced Desiccation

  2025cites this paper
• The inositol-phosphate synthase gene, MdMIPS1, enhances cold stress tolerance in transgenic apple plants.

  2025cites this paper
• A xyloglucan endotransglucosylase/hydrolase gene, IbXTH16, increases cold tolerance in transgenic sweetpotato

  2025cites this paper
• Integrated physiological, biochemical, and transcriptomic analysis of the cold-sensitive response in Mussaenda anomala

  2025cites this paper
• WRKY27-SPDS1 module of Ichang papeda (Citrus ichangensis) promotes cold tolerance by modulating spermidine content

  2025cites this paper
• Network disintegration of photosynthesis-antioxidant coordination underpins thermal vulnerability in Ochroma lagopus Swartz: A 5°C threshold triggers carbon starvation

  2025cites this paper
• Genome-Wide Identification of DREB Gene Family in Kiwifruit and Functional Characterization of Exogenous 5-ALA-Mediated Cold Tolerance via ROS Scavenging and Hormonal Signaling

  2025cites this paper
• Integrative Transcriptomic and Metabolomic Analysis Reveal the Flavonoid Biosynthesis of Physalis Under Low Temperature Stress

  2025cites this paper
• Cold-induced biochemical changes in leaves of two commercial clones of Eucalyptus

  2025cites this paper
• Cucurbita ficifolia Rootstock Enhances Resistance to Low-Temperature Stress in Cucumber

  2025cites this paper
• Effects of Temperature Fluctuations on Cabernet Sauvignon Branches and Wine Grape Appellation Yields: An Analysis Based on the Standardized Temperature Adaptation Index

  2025cites this paper
• Interplay between γ-aminobutyric acid metabolism and other crucial amino acid pathways in modulating plant growth and stress conditions

  2025cites this paper
• Pomegranate freezing tolerance evaluation and its relationship with biochemical parameters

  2024cites this paper
• Analysis of the Mechanism of Wood Vinegar and Butyrolactone Promoting Rapeseed Growth and Improving Low-Temperature Stress Resistance Based on Transcriptome and Metabolomics

  2024cites this paper
• Insights into physiological roles of flavonoids in plant cold acclimation

  2024cites this paper
• Biochemical parameters of carob (Ceratonia siliqua L.) pods and seeds as affected by different geographical sites in Morocco

  2024cites this paper
• From Sensing to Acclimation: The Role of Membrane Lipid Remodeling in Plant Responses to Low Temperatures.

  2024cites this paper
• Carbon and nitrogen signaling regulate FLOWERING LOCUS C and impact flowering time in Arabidopsis

  2024cites this paper
• Comparative study of free amino acids at metabolite and gene expression levels in Triticeae during cold acclimation

  2024influential citation
• Transcriptomic analysis of Asparagus officinalis cultivars with varying levels of freezing tolerance over fall acclimation and spring deacclimation periods

  2024cites this paper
• Comparative study of ambiguity in market collected ‘Sariva’ sample using HPTLC and antioxidant assay

  2024cites this paper
• GABA does not regulate stomatal CO2 signalling in Arabidopsis

  2024cites this paper
• Advances in plant response to low-temperature stress

  2024cites this paper
• UPP affects chloroplast development by interfering with chloroplast proteostasis

  2024cites this paper
• Autotetraploid synthetic seeds of Ficus carica L. exhibit a superior cold acclimation system than their corresponding diploids

  2024cites this paper
• VvbHLH036, a basic helix-loop-helix transcription factor regulates the cold tolerance of grapevine.

  2024cites this paper
• Comprehensive Evaluation of 65 Leafy Mustard Cultivars for Chilling Tolerance to Low Temperature Stress at the Seedling Stage

  2024cites this paper
• CsWRKY29, a key transcription factor in tea plant for freezing tolerance, ABA sensitivity, and sugar metabolism

  2024cites this paper
• Effect of Low Temperature on Content of Primary Metabolites in Two Wheat Genotypes Differing in Cold Tolerance

  2024cites this paper
• The AaERF64-AaTPPA module participates in cold acclimatization of Actinidia arguta (Sieb. et Zucc.) Planch ex Miq

  2024cites this paper
• MrERF039 transcription factor plays an active role in the cold response of Medicago ruthenica as a sugar molecular switch.

  2024cites this paper
• Low frequency of the wild-type freezing-tolerance LsCBF7 allele among lettuce population suggests a negative selection during domestication and breeding

  2024cites this paper
• Genome-Wide Identification of Freezing-Responsive Genes in a Rapeseed Line NTS57 Tolerant to Low-Temperature

  2024cites this paper
• Chloroplast-localized transporter OsNTP1 mediates cadmium transport from root to shoot and sugar metabolism in rice.

  2024cites this paper
• Uracil phosphoribosyltransferase is required to establish a functional cytochrome b6f complex.

  2024cites this paper
• Integrated metabolomics and transcriptomics analysis during seed germination of waxy corn under low temperature stress

  2023cites this paper
• Effect of Different Accumulative Temperate Zones in Heilongjiang on Glycine Soja Metabolites as Analyzed by Non-Target Metabolomics

  2023cites this paper
• Variations of Chlorophyll, Proline, and Abscisic Acid (ABA) Contents in Grapevines (Vitis Vinifera L.) Under Water Deficit Conditions

  2023cites this paper
• Plant Metabolomics: An Overview of the Role of Primary and Secondary Metabolites against Different Environmental Stress Factors

  2023cites this paper
• Evolutionary footprints of cold adaptation in arctic-alpine Cochlearia (Brassicaceae) – Evidence from freezing experiments and electrolyte leakage

  2023cites this paper
• Signaling and protection systems in the adaptation of plants to cold

  2023cites this paper
• A chromosome-level genome assembly for Erianthus fulvus provides insights into its biofuel potential and facilitates breeding for improvement of sugarcane

  2023cites this paper
• Lysine malonylation of DgnsLIPID TRANSFER PROTEIN1 at the K81 site improves cold resistance in chrysanthemum.

  2023cites this paper
• Rapid response of nonstructural carbohydrate allocation and photosynthesis to short photoperiod, low temperature, or elevated CO2 in Pinus strobus.

  2023cites this paper
• Transcriptome Analysis of Diurnal and Nocturnal-Warmed Plants, the Molecular Mechanism Underlying Cold Deacclimation Response in Deschampsia antarctica

  2023cites this paper
• Abiotic Stress in Rice: Visiting the Physiological Response and Its Tolerance Mechanisms

  2023cites this paper
• Anti-nutrient contents and methane reduction potential of medicinal plants from maize stover based diet

  2023cites this paper
• A large-effect fitness trade-off across environments is explained by a single mutation affecting cold acclimation

  2023cites this paper
• Integrated physiological and metabolomic analyses reveal changes during the natural senescence of Quercus mongolica leaves

  2023cites this paper
• Integration of Metabolome and Transcriptome Reveals the Major Metabolic Pathways and Potential Biomarkers in Response to Freeze-Stress Regulation in Apple (Malus domestica)

  2023cites this paper
• Responses of rice cultivars with different cold tolerance to chilling in booting and flowering stages: An experiment in Northeast China

  2023cites this paper
• Functional characterization of a cold related flavanone 3-hydroxylase from Tetrastigma hemsleyanum: an in vitro, in silico and in vivo study

  2023cites this paper
• Lipid and Amino Acid Pathway Metabolites Contribute to Cold Tolerance in Quercus wutaishanica

  2023cites this paper
• Deciphering the myth of cold tolerance in soybean: An overview of molecular breeding applications

  2023cites this paper
• Nanotechnology in improving photosynthesis under adverse climatic conditions: Cell to Canopy action

  2023cites this paper
• Integration of chromatin accessibility and gene expression reveals new regulators of cold hardening to enhance freezing tolerance in Prunus mume.

  2023cites this paper
• Advances and opportunities in unraveling cold‐tolerance mechanisms in the world's primary staple food crops

  2023cites this paper
• Genetic and lipidomic analyses reveal the key role of lipid metabolism for cold tolerance in maize.

  2023cites this paper
• Why did glutamate, GABA, and melatonin become intercellular signalling molecules in plants?

  2023cites this paper
• Combined Effect of Trehalose and Serendipita indica Inoculation Might Participate in Solanum lycopersicum Induced Cold Tolerance

  2023cites this paper
• Exploring the mechanism of blindness physiopathy in Brassica oleracea var italica L. by comprehensive transcriptomics and metabolomics analysis.

  2023cites this paper
• Transcription Factor VvDREB2A from Vitis vinifera Improves Cold Tolerance

  2023cites this paper
• Genome-wide identification of core components of ABA signaling and transcriptome analysis reveals gene circuits involved in castor bean (Ricinus communis L.) response to drought.

  2023cites this paper
• Nucleotide Imbalance, Provoked by Downregulation of Aspartate Transcarbamoylase Impairs Cold Acclimation in Arabidopsis

  2023cites this paper
• Effects of chiral herbicide dichlorprop on Arabidopsis thaliana metabolic profile and its implications for microbial communities in the phyllosphere

  2022cites this paper
• Wild relatives of plants as sources for the development of abiotic stress tolerance in plants

  2022cites this paper
• Temperature is an important driver for cold acclimation in garden roses

  2022cites this paper
• Transcriptional and physiological data revealed cold tolerance in a photo-thermo sensitive genic male sterile line Yu17S

  2022cites this paper
• Transcriptome and Expression Analysis of Genes Related to Regulatory Mechanisms in Holly (Ilex dabieshanensis) under Cold Stress

  2022cites this paper
• Jasmonate Positively Regulates Cold Tolerance by Promoting ABA Biosynthesis in Tomato

  2022cites this paper
• Diverse Physiological Roles of Flavonoids in Plant Environmental Stress Responses and Tolerance

  2022cites this paper
• Physio-biochemical and molecular stress regulators and their crosstalk for low-temperature stress responses in fruit crops: A review

  2022cites this paper
• Effects of Chilling Treatment on Baicalin, Baicalein, and Wogonin Biosynthesis in Scutellaria baicalensis Plantlets

  2022cites this paper
• The Arabidopsis thaliana trehalose-6-phosphate phosphatase gene AtTPPI improve chilling tolerance through accumulating soluble sugar and JA

  2022cites this paper
• Bioplastic (PHBV) Addition to Soil Alters Microbial Community Structure and Negatively Affects Plant-microbial Metabolic Functioning in Maize

  2022cites this paper
• Genome-wide transcriptome profiling revealed biological macromolecules respond to low temperature stress in Brassica napus L

  2022cites this paper
• Natural polymorphism of ZmICE1 contributes to amino acid metabolism that impacts cold tolerance in maize

  2022cites this paper
• Comparative carbohydrate metabolism in the shoots of a cold-hardy and a cold-sensitive peach (Prunus persica) cultivar during cold acclimation and deacclimation

  2022cites this paper
• Overexpression of PgCBF3 and PgCBF7 Transcription Factors from Pomegranate Enhances Freezing Tolerance in Arabidopsis under the Promoter Activity Positively Regulated by PgICE1

  2022cites this paper
• Transcription-associated metabolomic profiling reveals the critical role of frost tolerance in wheat

  2022cites this paper
• Combined nature and human selections reshaped peach fruit metabolome

  2022cites this paper
• Coronatine Enhances Chilling Tolerance of Tomato Plants by Inducing Chilling-Related Epigenetic Adaptations and Transcriptional Reprogramming

  2022cites this paper
• The effect of cold acclimation, deacclimation and reacclimation on metabolite profiles and freezing tolerance in winter wheat

  2022cites this paper
• Maize ZmBES1/BZR1-3 and -9 Transcription Factors Negatively Regulate Drought Tolerance in Transgenic Arabidopsis

  2022cites this paper
• Heat shock induced cold acclimation in cucumber through CsHSFA1d activated JA biosynthesis and signaling.

  2022cites this paper
• Nitrogen metabolism plays a major role in the adaptation of the halophytic forage species Sulla carnosa to water deficit and upon stress recovery

  2022cites this paper
• Short-term suboptimal low temperature has short- and long-term effects on melon seedlings

  2022cites this paper
• Metabolic signatures of Arabidopsis thaliana abiotic stress responses elucidate patterns in stress priming, acclimation, and recovery

  2022cites this paper
• Reprogramming of Plant Central Metabolism in Response to Abiotic Stresses: A Metabolomics View

  2022influential citation
• Recent insights into cell responses to cold stress in plants: Signaling, defence, and potential functions of phosphatidic acid

  2022cites this paper
• A Survey of Enhanced Cold Tolerance and Low-Temperature-Induced Anthocyanin Accumulation in a Novel Zoysia japonica Biotype

  2022cites this paper
• Comprehensive analysis of cucumber C-repeat/dehydration-responsive element binding factor family genes and their potential roles in cold tolerance of cucumber

  2022cites this paper
• Exogenous Glycine Betaine Application Improves Freezing Tolerance of Cabbage (Brassica oleracea L.) Leaves

  2021cites this paper
• Role of Soluble Sugars in Metabolism and Sensing Under Abiotic Stress

  2021cites this paper