TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse

Bo-Ra Na,Hye-Ran Kim,Indre Piragyte,H. Oh,M. Kwon,Uroos Akber,Hyun-Su Lee,Do-Sim Park,W. Song,Z. Park,S. Im,M. Rho,Young-Min Hyun,Minsoo Kim,C. Jun

Published 2015 in Journal of Cell Biology

ABSTRACT

TAGLN2 stabilizes cortical F-actin and thereby maintains F-actin contents at the immunological synapse, which allows T cell activation following T cell receptor stimulation.

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