Inactivation of the essential autophagy gene Atg5 results in selective accumulation of aggregation-prone proteins independently of substrate ubiquitination.
Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection
B. Riley,S. Kaiser,T. Shaler,Aylwin Ng,Taichi Hara,M. Hipp,K. Lage,R. Xavier,K. Ryu,K. Taguchi,Masayuki Yamamoto,Keiji Tanaka,N. Mizushima,M. Komatsu,R. Kopito
Published 2010 in Journal of Cell Biology
ABSTRACT
PUBLICATION RECORD
- Publication year
2010
- Venue
Journal of Cell Biology
- Publication date
2010-11-01
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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