The regulation and function of c-fos and other immediate early genes in the nervous system.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Neuron

• Publication date

  1990-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0896-6273(90)90106-PPMID 1969743
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterization of a bipartite activator domain in transcription factor CREB.

  1990cited by this paper
• Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB.

  1990cited by this paper
• Both the basic region and the ‘leucine zipper’ domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation.

  1990cited by this paper
• Preferential heterodimer formation by isolated leucine zippers from fos and jun.

  1989cited by this paper
• Regulation of synaptic transmission in the central nervous system: long-term potentiation.

  1989cited by this paper
• Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation

  1989cited by this paper
• Leucine zipper structure of the protein CRE‐BP1 binding to the cyclic AMP response element in brain.

  1989cited by this paper
• The NGFI-B gene, a transcriptionally inducible member of the steroid receptor gene superfamily: genomic structure and expression in rat brain after seizure induction

  1989cited by this paper
• 5-HT modulates protein synthesis and the expression of specific proteins during long-term facilitation in Aplysia sensory neurons.

  1989cited by this paper
• The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.

  1989cited by this paper
• Structure of the NGFI-A gene and detection of upstream sequences responsible for its transcriptional induction by nerve growth factor.

  1989cited by this paper
• Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun.

  1989cited by this paper
• In primary cultures of cerebellar granule cells the activation of N-methyl-D-aspartate-sensitive glutamate receptors induces c-fos mRNA expression.

  1989cited by this paper
• Two functionally different regions in Fos are required for the sequence-specific DNA interaction of the Fos/Jun protein complex

  1989cited by this paper
• Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers.

  1989cited by this paper
• A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

  1989cited by this paper
• c-Fos mRNA induction under vitamin B6 antagonist-induced seizure.

  1989cited by this paper
• Electrical activity, cAMP, and cytosolic calcium regulate mRNA encoding sodium channel α subunits in rat muscle cells

  1989cited by this paper
• Electrical activity, cAMP, and cytosolic calcium regulate mRNA encoding sodium channel alpha subunits in rat muscle cells.

  1989cited by this paper
• NGF induction of the gene encoding the protease transin accompanies neuronal differentiation in PC12 cells.

  1989cited by this paper
• Dynamic alterations occur in the levels and composition of transcription factor AP-1 complexes after seizure.

  1989cited by this paper
• Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence.

  1989cited by this paper
• Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

  1989cited by this paper
• jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun.

  1989cited by this paper
• Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction.

  1989cited by this paper
• The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation.

  1989cited by this paper
• The carboxy terminus of the viral Jun oncoprotein is required for complex formation with the cellular Fos protein.

  1989cited by this paper
• Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains.

  1989cited by this paper
• Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins.

  1989cited by this paper
• Regulation of muscle AChR α subunit gene expression by electrical activity: Involvement of protein kinase C and Ca 2+

  1989cited by this paper
• Regulation of proenkephalin by Fos and Jun.

  1989cited by this paper
• The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity.

  1989cited by this paper
• Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133.

  1989cited by this paper
• High-frequency discharge of dentate granule cells, but not long-term potentiation, induces c-fos protein.

  1988cited by this paper
• A nerve growth factor-regulated messenger RNA encodes a new intermediate filament protein

  1988cited by this paper
• Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences

  1988cited by this paper
• Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

  1988cited by this paper
• Influence of calcium ions on proopiomelanocortin mRNA levels in clonal anterior pituitary cells.

  1988cited by this paper
• The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.

  1988cited by this paper
• Calcium as a modulator of the immediate-early gene cascade in neurons.

  1988cited by this paper
• The role of the leucine zipper in the fos–jun interaction

  1988cited by this paper
• Fos and Jun: the AP-1 connection.

  1988cited by this paper
• Localization and induction of c-fos protein-like immunoreactive material in the nuclei of adult mammalian neurons.

  1988cited by this paper
• The NGF-inducible SCG10 mRNA encodes a novel membrane-bound protein present in growth cones and abundant in developing neurons.

  1988cited by this paper
• Nerve growth factor induces the genes for two proteins related to a family of calcium-binding proteins in PC12 cells.

  1988cited by this paper
• A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences.

  1988cited by this paper
• DNA binding activities of three murine Jun proteins: stimulation by Fos.

  1988cited by this paper
• Electrical stimulation in vivo increases the expression of proenkephalin mRNA and decreases the expression of prodynorphin mRNA in rat hippocampal granule cells.

  1988cited by this paper
• Convulsant-induced increase in transcription factor messenger RNAs in rat brain.

  1988cited by this paper
• Transcriptional and post-transcriptional effects of nerve growth factor on expression of the three neurofilament subunits in PC-12 cells.

  1988cited by this paper
• Neural and humoral factors separately regulate neuropeptide Y, enkephalin, and chromogranin A and B mRNA levels in rat adrenal medulla.

  1988cited by this paper
• c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities.

  1988cited by this paper
• Acetylcholine receptor alpha-, beta-, gamma-, and delta-subunit mRNA levels are regulated by muscle activity.

  1988cited by this paper
• Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro.

  1988cited by this paper
• Complexity of the early genetic response to growth factors in mouse fibroblasts

  1988cited by this paper
• The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins.

  1988cited by this paper
• A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily.

  1988cited by this paper
• Membrane depolarization and carbamoylcholine stimulate phosphatidylinositol turnover in intact nerve terminals.

  1988cited by this paper
• fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen

  1988cited by this paper
• The steroid and thyroid hormone receptor superfamily.

  1988cited by this paper
• Expression of c-fos protein in brain: metabolic mapping at the cellular level.

  1988cited by this paper
• A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization.

  1988cited by this paper
• Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA.

  1988cited by this paper
• A quantitative analysis of 2-D gels identifies proteins in which labeling is increased following long-term sensitization in Aplysia.

  1988cited by this paper
• Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells.

  1988cited by this paper
• Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene.

  1988cited by this paper
• Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells

  1988cited by this paper
• Common DNA binding site for Fos protein complexes and transcription factor AP-1.

  1988cited by this paper
• A gene activated by growth factors is related to the oncogene v-jun.

  1988cited by this paper
• Acetylcholine receptor α-, β-, γ-, and δ-subunit mRNA levels are regulated by muscle activity

  1988cited by this paper
• Nerve growth factor‐induced changes in neural cell adhesion molecule (N‐CAM) in PC12 cells.

  1987cited by this paper
• Cloning of tetradecanoyl phorbol ester-induced 'primary response' sequences and their expression in density-arrested Swiss 3T3 cells and a TPA non-proliferative variant.

  1987cited by this paper
• Induction of c-fos-like protein in spinal cord neurons following sensory stimulation

  1987cited by this paper
• Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP.

  1987cited by this paper
• Mechanisms of trans-synaptic regulation of gene expression

  1987cited by this paper
• Involvement of ion channels in the induction of proenkephalin A gene expression by nicotine and cAMP in bovine chromaffin cells.

  1987cited by this paper
• Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

  1987cited by this paper
• Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1.

  1987cited by this paper
• Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

  1987cited by this paper
• Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements.

  1987cited by this paper
• Induction of transiently expressed genes in PC-12 pheochromocytoma cells.

  1987cited by this paper
• Memories of fos

  1987cited by this paper
• Mapping patterns of c-fos expression in the central nervous system after seizure.

  1987cited by this paper
• Kindling stimulation induces c-fos protein(s) in granule cells of the rat dentate gyrus

  1987cited by this paper
• Avian sarcoma virus 17 carries the jun oncogene.

  1987cited by this paper
• Differential regulation of neuropeptide and proto-oncogene mRNA content in the hippocampus following recurrent seizures.

  1987cited by this paper
• Receptor Activation and Inositol Lipid Hydrolysis in Neural Tissues

  1987cited by this paper
• Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor.

  1987cited by this paper
• Mutation of the c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and the nuclear regulatory factor binding in vitro

  1987cited by this paper
• Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells.

  1987cited by this paper
• Biochemistry of information storage in the nervous system.

  1987cited by this paper
• A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor.

  1987cited by this paper
• Inducible binding of a factor to the c-fos enhancer.

  1986cited by this paper
• Role of ion flux in the control of c-fos expression

  1986cited by this paper
• A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia.

  1986cited by this paper
• Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression

  1986cited by this paper
• Barium modulates c-fos expression and post-translational modification.

  1986cited by this paper
• Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

  1986cited by this paper
• Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors.

  1986cited by this paper
• A cyclic AMP- and phorbol ester-inducible DNA element

  1986cited by this paper

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