Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  1997-06-10

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1073/PNAS.94.12.6474PMID 9177242PMCID PMC21074
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Renal fate of circulating advanced glycated end products (AGE): evidence for reabsorption and catabolism of AGE-peptides by renal proximal tubular cells

  1996cited by this paper
• Antibacterial activity of lysozyme and lactoferrin is inhibited by binding of advanced glycation–modified proteins to a conserved motif

  1995cited by this paper
• Advanced Glycation Endproducts Promote Adhesion Molecule (VCAM-1, ICAM-1) Expression and Atheroma Formation in Normal Rabbits

  1995cited by this paper
• Identification of the Major Site of Apolipoprotein B Modification by Advanced Glycosylation End Products Blocking Uptake by the Low Density Lipoprotein Receptor (*)

  1995cited by this paper
• Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose.

  1995cited by this paper
• Pathogenic effects of advanced glycosylation: biochemical, biologic, and clinical implications for diabetes and aging.

  1994cited by this paper
• Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease.

  1994cited by this paper
• Advanced glycation end products induce glomerular sclerosis and albuminuria in normal rats.

  1994cited by this paper
• Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency.

  1994cited by this paper
• Reactive glycosylation endproducts in diabetic uraemia and treatment of renal failure.

  1994cited by this paper
• The pathogenesis of atherosclerosis: a perspective for the 1990s

  1993cited by this paper
• beta 2-Microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis.

  1993cited by this paper
• Exogenous advanced glycosylation end products induce complex vascular dysfunction in normal animals: a model for diabetic and aging complications.

  1992cited by this paper
• Immunochemical detection of advanced glycosylation end products in vivo.

  1992cited by this paper
• Advanced glycosylation end products in patients with diabetic nephropathy.

  1991cited by this paper
• Mechanism of formation of the Maillard protein cross-link pentosidine. Glucose, fructose, and ascorbate as pentosidine precursors.

  1991cited by this paper
• Nutritional and toxicological aspects of the Maillard browning reaction in foods.

  1989cited by this paper
• Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications.

  1988cited by this paper
• Novel macrophage receptor for glucose-modified proteins is distinct from previously described scavenger receptors

  1986cited by this paper
• High-affinity-receptor-mediated uptake and degradation of glucose-modified proteins: a potential mechanism for the removal of senescent macromolecules.

  1985cited by this paper
• Physiological and safety aspects of Maillard browning of foods.

  1981cited by this paper
• Metabolic transit of early and advanced Maillard products.

  1981cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Nutritional consequences of the Maillard reaction. Amino acid availability from fructose-leucine and fructose-tryptophan in the rat.

  1973cited by this paper

• Enterococcus faecalis: A Key Metabolic Strain of Myofibrillar Protein-Bound Nε-(Carboxymethyl)lysine In Vitro Simulated Colon after Gastrointestinal Digestion.

  2026cites this paper
• Peony Root Extract Controls AGE–RAGE Interaction, Suppresses AGE Formation, and Reduces Skin Dullness

  2025cites this paper
• Tissue distribution of endogenously formed and orally administered low molecular mass advanced glycation end-products in rats.

  2025cites this paper
• The Potential Role of Advanced Glycation End Products in the Development of Kidney Disease

  2025cites this paper
• From Fork to Brain: The Role of AGE–RAGE Signaling and the Western Diet in Neurodegenerative Disease

  2025cites this paper
• LC-Orbitrap-MS/MS Analysis of Chosen Glycation Products in Infant Formulas

  2025cites this paper
• Uncovering the possible link between dietary advanced glycation end products and mortality risk: A systematic review and meta-analysis.

  2025cites this paper
• Oral bacterium contributes to periodontal inflammation by forming advanced glycation end products

  2025cites this paper
• Non-invasive evaluation of advanced glycation end products in hair as early markers of diabetes and aging

  2025cites this paper
• Dietary methylglyoxal induces renal lipotoxicity primarily through adipose tissue dysfunction in mice fed normal or obesogenic high-fat diets.

  2025cites this paper
• Balancing the dual nature of glycotoxins: interplay of diet, digestion, and gut microbiome

  2025cites this paper
• Dietary Advanced Glycation End Products (AGEs): A Modifiable Risk Factor in the Prevention of Chronic Diseases Associated with Aging?

  2025cites this paper
• Intestinal permeability, food antigens and the microbiome: a multifaceted perspective

  2025cites this paper
• Effect of Dietary Intake of Advanced Glycation End Products on Metabolic Parameters and Anthropometric Measurements in Adults

  2025cites this paper
• Comparison of Metabolic and Hormonal Profiles between Low-Advanced Glycation End Products (AGEs) and Standard AGEs-Containing Weight-Loss Diets in Overweight Phenotype-A PCOS Patients: A Randomized Clinical Trial

  2025cites this paper
• Advanced Glycation End-Products Acting as Immunomodulators for Chronic Inflammation, Inflammaging and Carcinogenesis in Patients with Diabetes and Immune-Related Diseases

  2024cites this paper
• The dynamic roles of advanced glycation end products.

  2024cites this paper
• Liquid Chromatography with Tandem Mass Spectrometry Analysis of Carboxymethyl Lysine in Indonesian Foods

  2024cites this paper
• Associations of circulating advanced glycation end products and their soluble receptors with cancer risk: A systematic review and meta-analysis of observational studies

  2024cites this paper
• Association of Serum Afamin Concentrations With Kidney Failure in Patients With CKD: Findings From the German CKD Cohort Study.

  2024cites this paper
• Revealing the Hypoglycemic Effect of Red Yeast Rice: Perspectives from the Inhibition of α-Glucosidase and the Anti-Glycation Capability by Ankaflavin and Monascin

  2024influential citation
• Dietary Restriction of Advanced Glycation End-Products (AGEs) in Patients with Diabetes: A Systematic Review of Randomized Controlled Trials

  2024cites this paper
• Effect of advanced glycation end-products in a wide range of medical problems including COVID-19.

  2024cites this paper
• Potential inhibitory effect of Auricularia auricula polysaccharide on advanced glycation end-products (AGEs).

  2024cites this paper
• Changes in α-Dicarbonyl Compound Contents during Storage of Various Fruits and Juices

  2024cites this paper
• The contribution of dietary advanced glycation end‐products and genetic risk in the development of inflammatory bowel disease: a prospective cohort study

  2024cites this paper
• The effect of synbiotic supplementation on plasma levels of advanced glycation end products and cardiovascular risk factors in hemodialysis patients: A double‐blind clinical trial

  2024cites this paper
• Comprehensive research on the properties of advanced glycation end products in food and biological samples and their harmful role in inducing metabolic diseases.

  2024cites this paper
• Advanced glycation end products and insulin resistance in diabetic nephropathy.

  2024cites this paper
• The Interaction between Human Microbes and Advanced Glycation End Products: The Role of Klebsiella X15 on Advanced Glycation End Products’ Degradation

  2024cites this paper
• Dietary advanced glycation end products, body composition, and anthropometric measures: A cross-sectional analysis in women with excess body weight.

  2024cites this paper
• Advanced glycation end products consumption and the decline of functional capacity in patients with Parkinson's disease: Cross-sectional study

  2024cites this paper
• Determination of α-Dicarbonyl compounds in traditional Chinese herbal medicines.

  2024cites this paper
• Fructose-mediated AGE-RAGE axis: approaches for mild modulation

  2024cites this paper
• A Mediterranean diet improves glycation markers in healthy people and in those with chronic diseases: a systematic review of clinical trials.

  2024cites this paper
• The Anti-AGEing and RAGEing Potential of Isothiocyanates

  2024influential citation
• Dietary Advanced Glycation End Products (AGEs) and Urinary Fluorescent AGEs in Children and Adolescents: Findings from the Italian I.Family Project

  2024cites this paper
• Developing a Portable Autofluorescence Detection System and Its Application in Biological Samples

  2024cites this paper
• Impact of Extrusion Parameters on the Formation of Nε-(Carboxymethyl)lysine, Nε-(Carboxyethyl)lysine and Acrylamide in Plant-Based Meat Analogues

  2024cites this paper
• Substituting animal protein with black soymilk reduces advanced glycation end product level and improves gut microbiota composition in obese prediabetic individuals: a randomized crossover intervention trial.

  2024cites this paper
• Contents and Correlations of Nε-(carboxymethyl)lysine, Nε-(carboxyethyl)lysine, Acrylamide and Nutrients in Plant-Based Meat Analogs

  2023cites this paper
• Do advanced glycation end products contribute to food allergy?

  2023cites this paper
• Exploring the molecular interactions and binding affinity of resveratrol and calcitriol with RAGE and its intracellular proteins and kinases involved in colorectal cancer

  2023influential citation
• Dietary and serum advanced glycation end-products and clinical outcomes in breast cancer.

  2023cites this paper
• Diet’s Role in Modifying Risk of Alzheimer’s Disease: History and Present Understanding

  2023cites this paper
• Ultra-High Temperature Treatment of Liquid Infant Formula, Systemic Immunity, and Kidney Development in Preterm Neonates.

  2023cites this paper
• İleri Glikasyon Son Ürünleri (AGE) ve Polikistik Over Sendromu İlişkisi

  2023cites this paper
• Higher dietary advanced glycation products intake is associated with increased risk of dementia, independent from genetic predisposition.

  2023cites this paper
• Long-term ingestion of β-lactoglobulin-bound AGEs induces colonic inflammation by modulating RAGE (TLR4)/MYD88/NF-κB signaling pathway and gut microbiota in mice

  2023cites this paper
• Effects of exogenous advanced glycation end products on oxidative stress and renal injury in healthy mice

  2023cites this paper
• Lifestyle Modification: Evaluation of the Effects of Physical Activity and Low-Glycemic-Index Mediterranean Diet on Fibrosis Score

  2023cites this paper
• The Effect of Free and Protein-Bound Maillard Reaction Products N-ε-Carboxymethyllysine, N-ε-Fructosyllysine, and Pyrraline on Nrf2 and NFκB in HCT 116 Cells.

  2023cites this paper
• Correlation between serum advanced glycation end products and dietary intake of advanced glycation end products estimated from home cooking and food frequency questionnaires.

  2023cites this paper
• A Role for Advanced Glycation End Products in Molecular Ageing

  2023cites this paper
• Effects of advanced glycation end products via oxidative stress on beta cells: insights from in vitro and in vivo studies and update on emerging therapies.

  2023cites this paper
• Signaling pathways in vascular function and hypertension: molecular mechanisms and therapeutic interventions

  2023cites this paper
• Recent updates in anti-glycation strategies: selection of natural products and lactic acid bacteria as potential inhibitors based on the multi-pathway anti-glycation targets

  2023cites this paper
• Dietary Advanced Glycation End products interacting with the intestinal epithelium: What do we really know?

  2023cites this paper
• Association between Urinary AGEs and Circulating miRNAs in Children and Adolescents with Overweight and Obesity from the Italian I.Family Cohort: A Pilot Study

  2023cites this paper
• Natural Biologics Accelerate Healing of Diabetic Foot Ulcers by Regulating Oxidative Stress.

  2022cites this paper
• Role of Advanced Glycation End Products in Intervertebral Disc Degeneration: Mechanism and Therapeutic Potential

  2022cites this paper
• Fructose might be a clue to the origin of preeclampsia insights from nature and evolution

  2022cites this paper
• Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs

  2022cites this paper
• The Intake of Dicarbonyls and Advanced Glycation Endproducts as Part of the Habitual Diet Is Not Associated with Intestinal Inflammation in Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients

  2022cites this paper
• Inhibition of advanced glycation end products and protein oxidation by leaf extracts and phenolics from Chilean bean landraces

  2022cites this paper
• Accumulation of Advanced Glycation End-Products in the Body and Dietary Habits

  2022cites this paper
• Bone matrix quality in a developing high-fat diet mouse model is altered by RAGE deletion.

  2022cites this paper
• Advanced Glycation End Products in Health and Disease

  2022cites this paper
• Comparison of tissue distribution of free and protein bound Nɛ-carboxymethyllysine after long-term oral administration to mice.

  2022cites this paper
• Role of RAGE in the Pathogenesis of Neurological Disorders

  2022cites this paper
• 5-Demethylnobiletin: Insights into its pharmacological activity, mechanisms, pharmacokinetics and toxicity.

  2022cites this paper
• Advanced Glycation End Products (AGEs) and Chronic Kidney Disease: Does the Modern Diet AGE the Kidney?

  2022cites this paper
• Dietary advanced glycation end products and cancer risk in Japan: From the Takayama study

  2022cites this paper
• High Molecular Weight Fucoidan Restores Intestinal Integrity by Regulating Inflammation and Tight Junction Loss Induced by Methylglyoxal-Derived Hydroimidazolone-1

  2022cites this paper
• Advanced glycation end-products in raw and commercially sterilized pork tenderloin and offal

  2022cites this paper
• Dietary Advanced Glycation End Products in an Elderly Population with Diabetic Nephropathy: An Exploratory Investigation

  2022cites this paper
• A 4-Week Diet Low or High in Advanced Glycation Endproducts Has Limited Impact on Gut Microbial Composition in Abdominally Obese Individuals: The deAGEing Trial

  2022cites this paper
• Differences in kinetics and dynamics of endogenous versus exogenous advanced glycation end products (AGEs) and their precursors.

  2022cites this paper
• Revisiting Methodologies for In Vitro Preparations of Advanced Glycation End Products

  2022cites this paper
• Food-Related Carbonyl Stress in Cardiometabolic and Cancer Risk Linked to Unhealthy Modern Diet

  2022cites this paper
• Nutrient and Maillard reaction product concentrations of commercially available pet foods and treats.

  2022cites this paper
• Dual Nature of RAGE in Host Reaction and Nurturing the Mother–Infant Bond

  2022cites this paper
• Is dietary intake of advanced glycation end products associated with mortality among adults with diabetes?

  2022cites this paper
• Receptor Mediated Effects of Advanced Glycation End Products (AGEs) on Innate and Adaptative Immunity: Relevance for Food Allergy

  2022cites this paper
• In Vitro Methodologies to Study the Role of Advanced Glycation End Products (AGEs) in Neurodegeneration

  2022cites this paper
• Could high heat cooking and food processing promoting neo-formed contaminants partially explain the high prevalence of chronic kidney disease in South Asian populations? A hypothesis.

  2022cites this paper
• Dietary Advanced Glycation End Products Shift the Gut Microbiota Composition and Induce Insulin Resistance in Mice

  2022cites this paper
• Advanced Glycation End Products: A Sweet Flavor That Embitters Cardiovascular Disease

  2022cites this paper
• Selective transportation and energy homeostasis regulation of dietary advanced glycation end-products in human intestinal Caco-2 cells.

  2022cites this paper
• The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis

  2022cites this paper
• Etiopathogenesis of insulin resistance

  2022cites this paper
• COMPREH ENS IVE REVIEWS IN FOOD SC IENCE AND FOOD SAFETY Aspects of high hydrostatic pressure food processing: Perspectives on technology and food safety

  2021cites this paper
• Circulating Advanced Glycation End Products and Their Soluble Receptors in Relation to All-Cause and Cardiovascular Mortality: A Systematic Review and Meta-analysis of Prospective Observational Studies.

  2021cites this paper
• Aspects of high hydrostatic pressure food processing: Perspectives on technology and food safety.

  2021cites this paper
• The Effect of Glycation Stress on Skeletal Muscle

  2021cites this paper
• The Maillard reactions

  2021cites this paper
• Effect of dietary advanced glycation end-products restriction on type 2 diabetes mellitus control: a systematic review.

  2021cites this paper
• Inflammation Meets Metabolism: Roles for the Receptor for Advanced Glycation End Products Axis in Cardiovascular Disease

  2021cites this paper
• Recent developments in in-vitro assessment of advanced glycation end products

  2021cites this paper
• Dysbiosis-Related Advanced Glycation Endproducts and Trimethylamine N-Oxide in Chronic Kidney Disease

  2021cites this paper