Bradykinin receptor subtype 1 expression and function in prostate cancer.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Cancer Research

• Publication date

  2003-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 12727816
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Requirement for direct cross-talk between B1 and B2 kinin receptors for the proliferation of androgen-insensitive prostate cancer PC3 cells.

  2003influential reference
• Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

  2002cited by this paper
• Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations

  2002cited by this paper
• β-Arrestins regulate a Ral-GDS–Ral effector pathway that mediates cytoskeletal reorganization

  2002cited by this paper
• Arresting developments in heptahelical receptor signaling and regulation.

  2002cited by this paper
• Lysophosphatidic acid‐regulated mitogenic ERK signaling in androgen‐insensitive prostate cancer PC‐3 cells

  2002cited by this paper
• Gα12 and Gα13 Negatively Regulate the Adhesive Functions of Cadherin*

  2002cited by this paper
• Focus on prostate cancer.

  2002cited by this paper
• Signalling: Seven-transmembrane receptors

  2002cited by this paper
• Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice

  2002cited by this paper
• Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin.

  2002cited by this paper
• Substrate specificity of human kallikrein 2 (hK2) as determined by phage display technology.

  2002cited by this paper
• Bradykinin B1 receptor up-regulation by interleukin-1beta and B1 agonist occurs through independent and synergistic intracellular signaling mechanisms in human lung fibroblasts.

  2001cited by this paper
• Bradykinin induced mitogenesis of androgen independent prostate cancer cells.

  2001cited by this paper
• Cancer Statistics, 2001

  2001cited by this paper
• Activation of MAPKs by Angiotensin II in Vascular Smooth Muscle Cells

  2001cited by this paper
• Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells.

  2001cited by this paper
• Comparison of tissue kallikrein and kinin receptor expression in gastric ulcers and neoplasms.

  2001cited by this paper
• Clinical states in prostate cancer: toward a dynamic model of disease progression.

  2000cited by this paper
• Essential role for G proteins in prostate cancer cell growth and signaling.

  2000cited by this paper
• Prostatic intraepithelial neoplasia

  2000cited by this paper
• The new human kallikrein gene family: implications in carcinogenesis.

  2000cited by this paper
• Focal Adhesion Kinase Facilitates Platelet-derived Growth Factor-BB-stimulated ERK2 Activation Required for Chemotaxis Migration of Vascular Smooth Muscle Cells*

  2000cited by this paper
• Activation of mitogen-activated protein kinase associated with prostate cancer progression.

  1999cited by this paper
• Treatment of prostate cancer

  1999cited by this paper
• Activation of extracellular signal-regulated kinase in human prostate cancer.

  1999cited by this paper
• Kininogenase activity of prostate-derived human glandular kallikrein (hK2) purified from seminal fluid.

  1999cited by this paper
• Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

  1999cited by this paper
• Differential Involvement of Gα12 and Gα13 in Receptor-mediated Stress Fiber Formation*

  1999cited by this paper
• Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation.

  1999cited by this paper
• c-Src-mediated Phosphorylation of the Epidermal Growth Factor Receptor on Tyr845 and Tyr1101 Is Associated with Modulation of Receptor Function*

  1999cited by this paper
• Update on the diagnosis and treatment of prostate cancer.

  1998cited by this paper
• Human Kallikrein 2 (hK2) and prostate-specific antigen (PSA): two closely related, but distinct, kallikreins in the prostate.

  1998cited by this paper
• The Sixth Transmembrane Domains of the Human B1 and B2 Bradykinin Receptors Are Structurally Compatible and Involved in Discriminating between Subtype-selective Agonists*

  1997cited by this paper
• The Role of Sequestration in G Protein-coupled Receptor Resensitization

  1997cited by this paper
• Receptors for bradykinin and related kinins: a critical analysis.

  1993influential reference
• Bioregulation of kinins: kallikreins, kininogens, and kininases.

  1992cited by this paper
• Prostatic intraepithelial neoplasia (PIN).

  1989cited by this paper

• The immunomodulatory potential of bradykinin signaling in autoimmune conditions.

  2026cites this paper
• Theranostic Potential of a New 64Cu-Labeled NOTA-R954 Peptide Conjugate for Kinin B1R Expressing Prostate Cancer

  2025cites this paper
• Bradykinin receptors in GtoPdb v.2025.3

  2025cites this paper
• Kinin B1 and B2 Receptors: Role in Tumor Progression and Pain Associated With Tumor and Anticancer Therapy.

  2025cites this paper
• GPCR-Gα13 Involvement in Mitochondrial Function, Oxidative Stress, and Prostate Cancer

  2024cites this paper
• Kinin Receptors B1 and B2 Mediate Breast Cancer Cell Migration and Invasion by Activating the FAK-Src Axis

  2024cites this paper
• Plasma Kinins- A Pharmacological Perspective

  2022cites this paper
• An overview of kinin mediated events in cancer progression and therapeutic applications.

  2022cites this paper
• Bradykinin receptors in GtoPdb v.2021.3

  2021cites this paper
• An Insight into GPCR and G-Proteins as Cancer Drivers

  2021cites this paper
• Activation of GPR56, a novel adhesion GPCR, is necessary for nuclear androgen receptor signaling in prostate cells

  2019cites this paper
• Bradykinin B1 receptor contributes to interleukin‐8 production and glioblastoma migration through interaction of STAT3 and SP‐1

  2019cites this paper
• Activation of PSGR with β-ionone suppresses prostate cancer progression by blocking androgen receptor nuclear translocation.

  2019cites this paper
• ADRB2-Targeting Therapies for Prostate Cancer

  2019cites this paper
• Bradykinin Receptor B1 and C-Reactive Protein as Prognostic Factors for Pharyngocutaneous Fistula Development After Laryngectomy

  2019cites this paper
• A Testosterone Metabolite 19-Hydroxyandrostenedione Induces Neuroendocrine Trans-Differentiation of Prostate Cancer Cells via an Ectopic Olfactory Receptor

  2018cites this paper
• Kinin B1 receptors as a therapeutic target for inflammation

  2018cites this paper
• Exploiting cancer’s phenotypic guise against itself: targeting ectopically expressed peptide G-protein coupled receptors for lung cancer therapy

  2017cites this paper
• ATP/pH Dual Responsive Nanoparticle with d-[des-Arg10 ]Kallidin Mediated Efficient In Vivo Targeting Drug Delivery.

  2017cites this paper
• 32 Calcium , Ca 2 +-Sensing Receptor and Breast Cancer

  2017cites this paper
• Synthesis and evaluation of a 68Ga-labeled bradykinin B1 receptor agonist for imaging with positron emission tomography.

  2017cites this paper
• Radiolabeled R954 Derivatives for Imaging Bradykinin B1 Receptor Expression with Positron Emission Tomography.

  2017cites this paper
• Exploiting cancer's phenotypic guise against itself: targeting ectopically expressed peptide G-protein coupled receptors for lung cancer therapy.

  2017cites this paper
• Activation of the human keratinocyte B1 bradykinin receptor induces expression and secretion of metalloproteases 2 and 9 by transactivation of epidermal growth factor receptor

  2016cites this paper
• Host kinin B1 receptor plays a protective role against melanoma progression

  2016cites this paper
• Repository of the Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association

  2016cites this paper
• G protein-coupled receptor GPR160 is associated with apoptosis and cell cycle arrest of prostate cancer cells

  2016cites this paper
• The activation of OR51E1 causes growth suppression of human prostate cancer cells

  2016cites this paper
• Surface-enhanced Raman studies of bradykinin using colloidal gold

  2016cites this paper
• Vibrational and ab initio molecular dynamics studies of bradykinin

  2016cites this paper
• Synthesis and Characterization of Bradykinin Derivatives Based on a β-Cyclodextrin Core

  2016cites this paper
• Non-androgen Signaling Pathways in Castration-Resistant Prostate Cancer

  2016cites this paper
• G protein-coupled receptors as promising cancer targets.

  2016cites this paper
• PET/CT imaging of the human bradykinin 1 receptor using radiolabeled peptides for cancer detection

  2016cites this paper
• Comparative Studies of Three 68Ga-Labeled [Des-Arg10]Kallidin Derivatives for Imaging Bradykinin B1 Receptor Expression with PET

  2015cites this paper
• Surface- and tip-enhanced Raman scattering of bradykinin onto the colloidal suspended Ag surface.

  2015cites this paper
• Identification and Functional Analysis of a Novel Tryptophyllin Peptide from the Skin of the Red-eye Leaf Frog, Agalychnis callidryas

  2015cites this paper
• Tip-enhanced Raman spectroscopy of bradykinin and its B2 receptor antagonists adsorbed onto colloidal suspended Ag nanowires.

  2015cites this paper
• (18)F-trifluoroborate derivatives of [des-arg(10)]kallidin for imaging bradykinin b1 receptor expression with positron emission tomography.

  2015cites this paper
• Intracellular signaling pathways involved in the release of IL-4 and VEGF from human keratinocytes by activation of kinin B1 receptor: functional relevance to angiogenesis

  2015cites this paper
• Kinin‐B1 and B2 receptor activity in proliferation and neural phenotype determination of mouse embryonic stem cells

  2015cites this paper
• Differential expression of the Bradykinin and Retinoic Acid Receptors in human colorectal cancer cell lines

  2015cites this paper
• Imaging Bradykinin B1 Receptor with 68Ga-Labeled [des-Arg10]Kallidin Derivatives: Effect of the Linker on Biodistribution and Tumor Uptake.

  2015cites this paper
• Expression and Functional Role of Orphan Receptor GPR158 in Prostate Cancer Growth and Progression

  2015cites this paper
• In vivo radioimaging of bradykinin receptor b1, a widely overexpressed molecule in human cancer.

  2015cites this paper
• Роль рецепторного аппарата калликреин-кининовой системы в пролиферативных процессах предстательной железы

  2014cites this paper
• The role of the Kinin-Kallikrein System in chronic lymphocytic leukaemia

  2014cites this paper
• B1 but not B2 bradykinin receptor agonists promote DU145 prostate cancer cell proliferation and migration.

  2014cites this paper
• The role of kinin receptors in cancer and therapeutic opportunities.

  2014cites this paper
• The role of seminal plasma in the regulation of inflammation and inflammatory pathways in the cervix: potential for cervical cancer progression and HIV transmission in South African women

  2014cites this paper
• Non-canonical signalling and roles of the vasoactive peptides angiotensins and kinins.

  2014cites this paper
• Identification of novel molecular targets for cutaneous squamous cell carcinoma

  2014cites this paper
• Functional and molecular characterization of kinin B1 and B2 receptors in human bladder cancer: implication of the PI3Kγ pathway

  2013cites this paper
• Unravelling the molecular complexity of GPCR‐mediated EGFR transactivation using functional genomics approaches

  2013cites this paper
• Bradykinin enhances cell migration in human prostate cancer cells through B2 receptor/PKCδ/c‐Src dependent signaling pathway

  2013cites this paper
• The kinin–kallikrein system: physiological roles, pathophysiology and its relationship to cancer biomarkers

  2013cites this paper
• Activation of the Kinin B1 Receptor Attenuates Melanoma Tumor Growth and Metastasis

  2013influential citation
• EXPRESSÃO E FUNÇÃO DOS RECEPTORES PARA CININAS EM CÉLULAS DE TUMOR DE BEXIGA: MECANISMOS RELACIONADOS

  2012cites this paper
• REGULATION OF TUMOUR-ANGIOGENESIS BY PROTEASE INHIBITORS AND RECEPTOR ANTAGONISTS

  2012influential citation
• Signaling Pathways Coupled to Activation of the Kinin B1 Receptor

  2012cites this paper
• GPCRs and cancer

  2012cites this paper
• Expression of HER2 and bradykinin B₁ receptors in precursor lesions of gallbladder carcinoma.

  2012cites this paper
• Discovery and therapeutic potential of kinin receptor antagonists

  2012cites this paper
• Kinin receptors as targets for cancer therapy

  2012cites this paper
• Kallikrein-kinin system: a surgical perspective in post-aprotinin era.

  2011cites this paper
• β-arrestin2 mediates β-2 adrenergic receptor signaling inducing prostate cancer cell progression.

  2011cites this paper
• The bradykinin B1 receptor antagonist R-954 inhibits Ehrlich tumor growth in rodents.

  2011cites this paper
• Effects of the Demethylating Agent, 5-Azacytidine, on Expression of the Kallikrein-Kinin Genes in Carcinoma Cells of the Lung and Pleura

  2011cites this paper
• Improved Fmoc synthesis of bradykinin.

  2011cites this paper
• Role of p115RhoGEF in the regulation of extracellular Ca2+‐induced choline kinase activation and prostate cancer cell proliferation

  2011cites this paper
• Calcium, Ca2+-Sensing Receptor and Breast Cancer

  2011cites this paper
• 14 Kinins: kallikreins and kinins in cancer

  2011cites this paper
• 10 Kallikreins and kinin receptors: Modulators of skin homeostasis

  2011cites this paper
• Tumor interactions with soluble factors and the nervous system

  2010cites this paper
• Bradykinin B1 receptor antagonists as potential therapeutic agents for pain.

  2010cites this paper
• Guided Tour of Cell Migration: Signals and Pathways

  2010cites this paper
• Regulation of Kinin Receptor Expression in Heart Failure with a Focus on Vascular Endothelium

  2010cites this paper
• Bradykinin‐induced cell migration and COX‐2 production mediated by the bradykinin B1 receptor in glioma cells

  2010cites this paper
• Activation of an Olfactory Receptor Inhibits Proliferation of Prostate Cancer Cells*

  2009cites this paper
• Stimulation of the bradykinin B1 receptor induces the proliferation of estrogen-sensitive breast cancer cells and activates the ERK1/2 signaling pathway

  2009cites this paper
• Bradykinin enhances cell migration in human chondrosarcoma cells through BK receptor signaling pathways

  2009influential citation
• Caveolae Contribute to the Apoptosis Resistance Induced by the α1A-Adrenoceptor in Androgen-Independent Prostate Cancer Cells

  2009cites this paper
• Bradykinin-induced Ca 2+ signaling in human oral squamous cell carcinoma HSC-3 cells

  2009cites this paper
• Peptide hormone regulation of angiogenesis.

  2009cites this paper
• B-1 Bradykinin Receptor

  2008cites this paper
• Influence of the Kallikrein-Kinin System on Prostate and Breast Tumour Angiogenesis

  2008cites this paper
• Activation of kinin B1 receptor triggers differentiation of cultured human keratinocytes

  2008cites this paper
• Structural modification of the highly potent peptide bradykinin B1 receptor antagonist B9958.

  2008cites this paper
• Kinin B2 Receptor Mediates Induction of Cyclooxygenase-2 and Is Overexpressed in Head and Neck Squamous Cell Carcinomas

  2008cites this paper
• Doxorubicin cardiomyopathy-induced inflammation and apoptosis are attenuated by gene deletion of the kinin B1 receptor

  2008cites this paper
• Erratum

  2008cites this paper
• Kinin B 2 Receptor Mediates Induction of Cyclooxygenase-2 and Is Overexpressed in Head and Neck Squamous Cell Carcinomas

  2008cites this paper
• Epinephrine Protects Cancer Cells from Apoptosis via Activation of cAMP-dependent Protein Kinase and BAD Phosphorylation*

  2007cites this paper
• The renin angiotensin system in the regulation of angiogenesis.

  2007cites this paper
• Androgen-regulated genes differentially modulated by the androgen receptor coactivator L-dopa decarboxylase in human prostate cancer cells

  2007influential citation
• Antagonist, partial agonist and antiproliferative actions of B‐9870 (CU201) as a function of the expression and density of the bradykinin B1 and B2 receptors

  2007influential citation
• G-protein-coupled receptors and cancer

  2007cites this paper
• Neurotransmitter effects on tumor cells and leukocytes.

  2007cites this paper
• Inhibition of human and rabbit arterial smooth muscle cell migration mediated by the kinin B1 receptor: role of receptor density and released mediators.

  2006cites this paper
• Expression and function of lysophosphatidic acid LPA1 receptor in prostate cancer cells.

  2006cites this paper