Dietary flavonoids and the development of type 2 diabetes and cardiovascular diseases: review of recent findings

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Current Opinion in Lipidology

• Publication date

  2013-02-01

• Fields of study

  Agricultural and Food Sciences, Medicine

• Identifiers
  DOI 10.1097/MOL.0b013e32835bcdffPMID 23254472
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2012influential reference
• Chronic Ingestion of Flavan-3-ols and Iso fl avones Improves Insulin Sensitivity and Lipoprotein Status and Attenuates Estimated 10-Year CVD Risk in Medicated Postmenopausal Women With Type 2 Diabetes A 1-year, double-blind, randomized, controlled trial

  2012cited by this paper
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  2011influential reference
• Hesperidin contributes to the vascular protective effects of orange juice: a randomized crossover study in healthy volunteers.

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  2008cited by this paper
• Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials.

  2008influential reference
• Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies?

  2008cited by this paper
• Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women.

  2007cited by this paper
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  2007cited by this paper
• EuroFIR-BASIS - a combined composition and biological activity database for bioactive compounds in plant-based foods

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  2006cited by this paper
• Dietary flavonoids and flavonoid-rich foods are not associated with risk of type 2 diabetes in postmenopausal women.

  2006cited by this paper
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  2002cited by this paper
• Antioxidant flavonols from fruits, vegetables and beverages: measurements and bioavailability.

  2000cited by this paper

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