Regulation of T cell receptor signaling by activation-induced zinc influx

Mingcan Yu,Won-Woo Lee,D. Tomar,S. Pryshchep,M. Cześnikiewicz-Guzik,David L. Lamar,Guangjin Li,Karnail Singh,L. Tian,C. Weyand,J. Goronzy

Published 2011 in Journal of Experimental Medicine

ABSTRACT

Zinc enhances TCR signaling in part by inhibiting Shp-1 recruitment to the TCR synapse.

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