The necessary junk: new functions for transposable elements.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Human Molecular Genetics

• Publication date

  2007-10-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/HMG/DDM196PMID 17911158
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• All APOBEC3 family proteins differentially inhibit LINE-1 retrotransposition

  2007cited by this paper
• Different evolutionary fates of recently integrated human and chimpanzee LINE-1 retrotransposons.

  2007cited by this paper
• Mobile element-based forensic genomics.

  2007cited by this paper
• Stem cell regulatory function mediated by expression of a novel mouse Oct4 pseudogene.

  2007cited by this paper
• L1 retrotransposition can occur early in human embryonic development.

  2007cited by this paper
• Developmentally Regulated piRNA Clusters Implicate MILI in Transposon Control

  2007cited by this paper
• A Slicer-Mediated Mechanism for Repeat-Associated siRNA 5' End Formation in Drosophila

  2007cited by this paper
• Selective inhibition of Alu retrotransposition by APOBEC3G.

  2007cited by this paper
• Evolutionary dynamics of transposable elements in the short-tailed opossum Monodelphis domestica.

  2007cited by this paper
• RNA-editing-mediated exon evolution

  2007cited by this paper
• Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

  2007cited by this paper
• Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres

  2007cited by this paper
• Selection against LINE-1 retrotransposons results principally from their ability to mediate ectopic recombination.

  2007cited by this paper
• Which transposable elements are active in the human genome?

  2007cited by this paper
• LINE-1 retrotransposition in human embryonic stem cells.

  2007influential reference
• Noncoding RNAs in the mammalian central nervous system.

  2006cited by this paper
• Distinct catalytic and non-catalytic roles of ARGONAUTE4 in RNA-directed DNA methylation

  2006cited by this paper
• Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation

  2006cited by this paper
• A distal enhancer and an ultraconserved exon are derived from a novel retroposon

  2006cited by this paper
• Generation of neuronal variability and complexity

  2006cited by this paper
• Alu elements contain many binding sites for transcription factors and may play a role in regulation of developmental processes

  2006cited by this paper
• Alu elements as regulators of gene expression

  2006cited by this paper
• LINE-1 RNA splicing and influences on mammalian gene expression

  2006cited by this paper
• APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons.

  2006cited by this paper
• APOBEC3 Proteins Inhibit Human LINE-1 Retrotransposition*

  2006cited by this paper
• Emergence of primate genes by retrotransposon-mediated sequence transduction

  2006influential reference
• Fitness cost of LINE-1 (L1) activity in humans.

  2006cited by this paper
• Active retrotransposition by a synthetic L1 element in mice

  2006cited by this paper
• High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition

  2006cited by this paper
• Selection against Line-1 Retrotransposons Results Principally from Their Ability to Mediate Ectopic Recombination

  2006cited by this paper
• Human genomic deletions mediated by recombination between Alu elements.

  2006cited by this paper
• A Novel Repeat-Associated Small Interfering RNA-Mediated Silencing Pathway Downregulates Complementary Sense gypsy Transcripts in Somatic Cells of the Drosophila Ovary

  2006cited by this paper
• Alu elements within human mRNAs are probable microRNA targets.

  2006cited by this paper
• Recently mobilized transposons in the human and chimpanzee genomes.

  2006cited by this paper
• MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis

  2006cited by this paper
• Characterization of the piRNA Complex from Rat Testes

  2006cited by this paper
• Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome.

  2006cited by this paper
• RNA polymerase III transcribes human microRNAs

  2006influential reference
• Functional noncoding sequences derived from SINEs in the mammalian genome.

  2006cited by this paper
• Cellular inhibitors of long interspersed element 1 and Alu retrotransposition.

  2006cited by this paper
• APOBEC3B and APOBEC3F Inhibit L1 Retrotransposition by a DNA Deamination-independent Mechanism*

  2006cited by this paper
• L1 retrotransposition in nondividing and primary human somatic cells.

  2006cited by this paper
• L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells

  2006cited by this paper
• Human Population Genetic Structure and Diversity Inferred from Polymorphic L1(LINE-1) and Alu Insertions

  2006cited by this paper
• Comparison of multiple vertebrate genomes reveals the birth and evolution of human exons

  2006influential reference
• Retroposition of processed pseudogenes: the impact of RNA stability and translational control.

  2006cited by this paper
• Extensive individual variation in L1 retrotransposition capability contributes to human genetic diversity.

  2006cited by this paper
• A Distinct Small RNA Pathway Silences Selfish Genetic Elements in the Germline

  2006cited by this paper
• Alu RNP and Alu RNA regulate translation initiation in vitro

  2006cited by this paper
• RNA editing level in the mouse is determined by the genomic repeat repertoire.

  2006cited by this paper
• Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition

  2005cited by this paper
• Multiple Retropseudogenes from Pluripotent Cell-specific Gene Expression Indicates a Potential Signature for Novel Gene Identification*

  2005cited by this paper
• SVA elements: a hominid-specific retroposon family.

  2005cited by this paper
• Mammalian microRNAs derived from genomic repeats.

  2005cited by this paper
• LINEs, SINEs and processed pseudogenes: parasitic strategies for genome modeling

  2005cited by this paper
• Human retroelements may introduce intragenic polyadenylation signals

  2005cited by this paper
• A potential role for RNA interference in controlling the activity of the human LINE-1 retrotransposon

  2005cited by this paper
• Natural Genetic Variation Caused by Transposable Elements in Humans

  2004cited by this paper
• Genome sequence of the Brown Norway rat yields insights into mammalian evolution

  2004cited by this paper
• The insertional history of an active family of L1 retrotransposons in humans.

  2004cited by this paper
• Genetic variation of recent Alu insertions in human populations

  2004cited by this paper
• Millions of years of evolution preserved: a comprehensive catalog of the processed pseudogenes in the human genome.

  2003cited by this paper
• Whole-genome screening indicates a possible burst of formation of processed pseudogenes and Alu repeats by particular L1 subfamilies in ancestral primates

  2003cited by this paper
• Hot L1s account for the bulk of retrotransposition in the human population

  2003cited by this paper
• Alu repeats and human genomic diversity

  2002cited by this paper
• Initial sequencing and comparative analysis of the mouse genome

  2002cited by this paper
• Selective stimulation of translational expression by Alu RNA.

  2002cited by this paper
• Initial sequencing and analysis of the human genome

  2001cited by this paper
• Specific interference with gene function by double-stranded RNA in early mouse development

  2000cited by this paper
• Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference.

  2000cited by this paper
• The Mouse Gene Encoding the Testis-Specific Isoform of Poly(A) Binding Protein (Pabp2) Is an Expressed Retroposon: Intimations That Gene Expression in Spermatogenic Cells Facilitates the Creation of New Genes

  1998cited by this paper
• The frequency and position of Alu repeats in cDNAs, as determined by database searching.

  1995cited by this paper
• Cell stress and translational inhibitors transiently increase the abundance of mammalian SINE transcripts.

  1995cited by this paper
• Intron phylogeny: a new hypothesis.

  1991cited by this paper
• Origin and evolution of retroelements based upon their reverse transcriptase sequences.

  1990cited by this paper
• Selfish genes, the phenotype paradigm and genome evolution

  1980cited by this paper
• Selfish DNA: the ultimate parasite

  1980cited by this paper

• The Chromaverse Is Colored by Triplexes Formed Through the Interactions of Noncoding RNAs with HNPRNPU, TP53, AGO, REL Proteins, Intrinsically-Disordered Regions, and Flipons

  2026cites this paper
• Mutation protocols share with sexual reproduction the physiological role of producing genetic variation within ‘constraints that deconstrain’

  2024cites this paper
• High resolution genomes of multiple Xiphophorus species provide new insights into microevolution, hybrid incompatibility, and epistasis

  2023cites this paper
• Frequency of cytosine methylation in the adjacent regions of soybean retrotransposon SORE-1 depends on chromosomal location.

  2023cites this paper
• Comparative analysis of repeat content in plant genomes, large and small

  2023cites this paper
• Chromosome-level genome and recombination map of the male buffalo

  2022cites this paper
• Not functional yet a difference maker: junk DNA as a case study

  2022cites this paper
• Clustered and dispersed chromosomal distribution of the two classes of Revolver transposon family in rye (Secale cereale)

  2021cites this paper
• Mitophagy: At the heart of mitochondrial quality control in cardiac aging and frailty.

  2021cites this paper
• Gallop Racing Shifts Mature mRNA towards Introns: Does Exercise-Induced Stress Enhance Genome Plasticity?

  2020cites this paper
• AGO2 and its partners: a silencing complex, a chromatin modulator, and new features

  2020cites this paper
• What Doesn't Kill You Makes You Stronger: Transposons as Dual Players in Chromatin Regulation and Genomic Variation

  2020cites this paper
• A model of autowave self-organization as a hierarchy of active media in the biological evolution

  2020cites this paper
• Genome Size Dynamics within Multiple Genera of Diploid Seed Plants

  2020cites this paper
• Insights into the heterochromatin evolution in the genus Melipona (Apidae: Meliponini)

  2020cites this paper
• Chromosomal distribution of the retroelements Rex 1, Rex 3 and Rex 6 in species of the genus Harttia and Hypostomus (Siluriformes: Loricariidae)

  2019cites this paper
• Transposon Ecology: The Power of Community Ecology Methods on Genomic Transposable Element Data

  2019cites this paper
• Conciencia en e-prime. La (di)solución del problema mente-cerebro

  2019cites this paper
• Cause of Cambrian Explosion-Terrestrial or Co

  2019cites this paper
• Oxidative stress causes Alu RNA accumulation via PIWIL4 sequestration into stress granules

  2019cites this paper
• Evolutionary history and classification of Micropia retroelements in Drosophilidae species

  2019cites this paper
• ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer

  2019cites this paper
• Transcription of soybean retrotransposon SORE-1 is temporally upregulated in developing ovules

  2018cites this paper
• Do Human Endogenous Retroviruses Contribute to Multiple Sclerosis, and if So, How?

  2018cites this paper
• The Role of Transposable Elements in Speciation

  2018cites this paper
• New Supercoiling Theory and Model of Chromosomal Structures in Eukaryotic Cells

  2018cites this paper
• Developmentally regulated transcription and silencing cycle of nuclear RNAi-targeted LTR retrotransposons in Caenorhabditis elegans

  2018cites this paper
• Cause of Cambrian Explosion - Terrestrial or Cosmic?

  2018cites this paper
• Histoire évolutive des remaniements chromosomiques en liaison avec la mobilisation d'éléments transposables chez les téléostéens antarctiques Nototheniidae : la radiation adaptative du groupe " Trematomus "

  2018cites this paper
• The spatial and temporal dynamics of the nuclear RNAi-targeted RNA transcripts in Caenorhabditis elegans

  2018cites this paper
• The role of transposable elements in functional evolution of amphioxus genome: the case of opsin gene family

  2018cites this paper
• Genome and stress-reaction in animals and humans

  2018cites this paper
• The spatial and temporal dynamics of nuclear RNAi-targeted retrotransposon transcripts in Caenorhabditis elegans

  2018cites this paper
• Peroxisome Proliferator Activated Receptor Agonists Modulate Transposable Element Expression in Brain and Liver

  2018cites this paper
• Retrotransposons and the Mammalian Germline

  2017cites this paper
• Enhancer SINEs Link Pol III to Pol II Transcription in Neurons

  2017cites this paper
• Potential impact of primate‐specific SVA retrotransposons during the evolution of human cognitive function.

  2017cites this paper
• Repetitive Sequences in the Potato and Related Genomes

  2017cites this paper
• The genomes and transposable elements in plants: are they friends or foes?

  2017cites this paper
• Uloga transpozona u nastanku introna

  2017cites this paper
• Alignment and reconciliation strategies for large-scale de novo assembly

  2016cites this paper
• Transposable elements activity reveals punctuated patterns of speciation in mammals

  2016cites this paper
• The canine X chromosome is a sink for canine endogenous retrovirus transposition

  2016cites this paper
• Histone Deacetylases as Therapeutic Targets in Neurodegenerative Diseases

  2016cites this paper
• L1 Retrotransposition in Neural Progenitor Cells.

  2016cites this paper
• LINE-1 distribution in six rodent genomes follow a species-specific pattern

  2016cites this paper
• Characterization of irritans mariner-like elements in the olive fruit fly Bactrocera oleae (Diptera: Tephritidae): evolutionary implications

  2016cites this paper
• Virus-like attachment sites as structural landmarks of plants retrotransposons

  2016cites this paper
• Primate specific retrotransposons, SVAs, in the evolution of networks that alter brain function

  2016cites this paper
• Novel Role of 3’UTR-Embedded Alu Elements as Facilitators of Processed Pseudogene Genesis and Host Gene Capture by Viral Genomes

  2016cites this paper
• DNA Elements Tetris: A Strategy for Gene Correction

  2016cites this paper
• The Cell-Free Mitochondrial DNA: A Novel Biomarker of Cardiovascular Risk?

  2016cites this paper
• Evaluation and validation of retrotransposons-based kits for DNA analysis of degraded biological evidence and rootless hair

  2016cites this paper
• Trend of different molecular markers in the last decades for studying human migrations.

  2015cites this paper
• A Deluge of Complex Repeats: The Solanum Genome

  2015cites this paper
• Species-specific exon loss in human transcriptomes.

  2015cites this paper
• U6 snRNA Pseudogenes: Markers of Retrotransposition Dynamics in Mammals

  2015cites this paper
• Adaptation and possible ancient interspecies introgression in pigs identified by whole-genome sequencing

  2015cites this paper
• Changes of Osvaldo expression patterns in germline of male hybrids between the species Drosophila buzzatii and Drosophila koepferae

  2015cites this paper
• A Unique HMG-Box Domain of Mouse Maelstrom Binds Structured RNA but Not Double Stranded DNA

  2015cites this paper
• What's in a genome? The C-value enigma and the evolution of eukaryotic genome content

  2015cites this paper
• Transposable element-driven transcript diversification and its relevance to genetic disorders.

  2015cites this paper
• Strong nucleosomes reside in meiotic centromeres of C. elegans

  2015cites this paper
• Circulating Cell-Free Mitochondrial DNA as Biomarker of Cardiovascular risk: New Challenges of Old Findings

  2015cites this paper
• Variation in salamanders: an essay on genomes, development, and evolution.

  2015cites this paper
• Transposable Elements in Neural Progenitor Cells

  2015influential citation
• Mating System Shifts and Transposable Element Evolution in Plants

  2015cites this paper
• DNA Revolution and the Social and Behavioral Sciences

  2015cites this paper
• Auswirkungen ausgewählter Einflussfaktoren auf die genomweite DNA-Methylierung beim Menschen

  2015cites this paper
• Transposable elements dynamics in taxa with different reproductive strategies or speciation rate

  2014cites this paper
• TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells

  2014cites this paper
• Transposable elements and psychiatric disorders

  2014cites this paper
• LINE-1 retrotransposons: from ‘parasite’ sequences to functional elements

  2014cites this paper
• Mobile DNA elements in the generation of diversity and complexity in the brain

  2014cites this paper
• Reflections on Ancestral Haplotypes: Medical Genomics, Evolution, and Human Individuality

  2014cites this paper
• Physiology of the read–write genome

  2014cites this paper
• Dietary and Flight Energetic Adaptations in a Salivary Gland Transcriptome of an Insectivorous Bat

  2014cites this paper
• Epigenetic memory: the Lamarckian brain

  2014cites this paper
• Evolutionary history and diversification of duplicated fatty-acyl elongase genes of Atlantic salmon (Salmo salar)

  2014cites this paper
• Roles of piRNA Pathway Components Piwi and Aubergine In Drosophila melanogaster Female Germline Development

  2014cites this paper
• Transposition-Driven Genomic Heterogeneity in the Drosophila Brain

  2013cites this paper
• An epigenetic framework for neurodevelopmental disorders: from pathogenesis to potential therapy.

  2013cites this paper
• Functional Mapping of Mu Transposition Machinery : MuA Protein Modification and Engineering for Hyperactivity

  2013cites this paper
• How do mammalian transposons induce genetic variation? A conceptual framework

  2013cites this paper
• Environmental stress and transposon transcription in the mammalian brain

  2013cites this paper
• Distinctive Expansion of Potential Virulence Genes in the Genome of the Oomycete Fish Pathogen Saprolegnia parasitica

  2013cites this paper
• Hominid retrotransposons as a modulator of genomic function

  2013influential citation
• Integrating Omics Approaches in Sugarcane Improvement

  2013cites this paper
• Multidimensional control of cell structural robustness

  2013cites this paper
• Epigenetic Tracking: a Model for Multicellular Biology

  2013cites this paper
• Angiotensin Converting Enzyme Insertion/Deletion (ACE I/D) and Methylene Tetrahydrofolate Reductase C677T (MTHFR C677T) genetic polymorphisms in the pathogenesis of abdominal aortic aneurysms (AAA)

  2013cites this paper
• Identification of Specific Markers Linked to Regional Differentiation of Warburgia ugandensis

  2013cites this paper
• Differential LINE-1 regulation in pluripotent stem cells of humans and other great apes

  2013cites this paper
• Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline

  2013cites this paper
• A gene expression restriction network mediated by sense and antisense Alu sequences located on protein-coding messenger RNAs

  2013cites this paper
• L1 RETROTRANSPOSITION AS A SOURCE OF SOMATIC GENOME MOSAICISM IN NEURONS

  2013cites this paper
• Caractérisation de l'expression des éléments Alu et du phénomène d'édition de l'ARN chez l'humain et la souris

  2012cites this paper
• Characterization of rainbow trout gonad, brain and gill deep cDNA repertoires using a Roche 454-Titanium sequencing approach.

  2012cites this paper
• The evolutionary dynamics of transposable elements in eukaryote genomes.

  2012cites this paper
• Posttraumatic regeneration involves differential expression of long terminal repeat (LTR) retrotransposons

  2012cites this paper