Initial sequencing and comparative analysis of the mouse genome

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Nature

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nature01262PMID 12466850
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Compositional patterns in vertebrate genomes: Conservation and change in evolution

  2005cited by this paper
• The compositional distribution of coding sequences and DNA molecules in humans and murids

  2005cited by this paper
• Compositional compartmentalization and gene composition in the genome of vertebrates

  2005cited by this paper
• Compositional constraints and genome evolution

  2005cited by this paper
• Genes, isochores and bands in human chromosomes 21 and 22

  2004cited by this paper
• Human-mouse alignments with BLASTZ.

  2003cited by this paper
• Comparative gene prediction in human and mouse.

  2003cited by this paper
• Comparison of mouse and human genomes followed by experimental verification yields an estimated 1,019 additional genes

  2003cited by this paper
• Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution.

  2003cited by this paper
• Leveraging the mouse genome for gene prediction in human: from whole-genome shotgun reads to a global synteny map.

  2003cited by this paper
• The phusion assembler.

  2003cited by this paper
• Distinguishing regulatory DNA from neutral sites.

  2003cited by this paper
• SLAM: cross-species gene finding and alignment with a generalized pair hidden Markov model.

  2003cited by this paper
• Whole-genome sequence assembly for mammalian genomes: Arachne 2.

  2003cited by this paper
• An Expanding Universe of Noncoding RNAs

  2002cited by this paper
• Structure and function of natural killer cell receptors: multiple molecular solutions to self, nonself discrimination.

  2002cited by this paper
• Using the transcriptome to annotate the genome

  2002cited by this paper
• The K(A)/K(S) ratio test for assessing the protein-coding potential of genomic regions: an empirical and simulation study.

  2002cited by this paper
• PatternHunter: faster and more sensitive homology search

  2002cited by this paper
• The role of lineage-specific gene family expansion in the evolution of eukaryotes.

  2002cited by this paper
• Recent improvements to the SMART domain-based sequence annotation resource

  2002cited by this paper
• Deficient pheromone responses in mice lacking a cluster of vomeronasal receptor genes

  2002cited by this paper
• The Structure of Haplotype Blocks in the Human Genome

  2002cited by this paper
• Identification and characterization of a dense cluster of placenta-specific cysteine peptidase genes and related genes on mouse chromosome 13.

  2002cited by this paper
• Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays

  2002cited by this paper
• The olfactory receptor gene superfamily of the mouse

  2002cited by this paper
• The mosaic structure of variation in the laboratory mouse genome

  2002cited by this paper
• High-throughput retroviral tagging to identify components of specific signaling pathways in cancer

  2002cited by this paper
• Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

  2002cited by this paper
• Evolution of transcription factor binding sites in Mammalian gene regulatory regions: conservation and turnover.

  2002cited by this paper
• Predicting protein cellular localization using a domain projection method.

  2002cited by this paper
• Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

  2002cited by this paper
• Numerous potentially functional but non-genic conserved sequences on human chromosome 21

  2002cited by this paper
• Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice

  2002cited by this paper
• Human l1 retrotransposition is associated with genetic instability in vivo.

  2002cited by this paper
• SCORE FUNCTIONS FOR ASSESSING CONSERVATION IN LOCALLY ALIGNED REGIONS OF DNA FROM TWO SPECIES UCSC TECH REPORT UCSC-CRL-02-30

  2002cited by this paper
• Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome.

  2002cited by this paper
• MHC class I recognition by Ly49 natural killer cell receptors.

  2002cited by this paper
• Genomic deletions created upon LINE-1 retrotransposition.

  2002cited by this paper
• Molecular clocks in reptiles: life history influences rate of molecular evolution.

  2002cited by this paper
• Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis

  2002cited by this paper
• Comparative genomic sequence analysis of the human chromosome 21 Down syndrome critical region.

  2002cited by this paper
• The vitelliform macular dystrophy protein defines a new family of chloride channels

  2002cited by this paper
• A physical map of the mouse genome

  2002cited by this paper
• Control and expression of cystatin C by mouse decidual cultures

  2002cited by this paper
• ARACHNE: a whole-genome shotgun assembler.

  2002cited by this paper
• The natural history of protein domains.

  2002cited by this paper
• A draft sequence of the rice genome (Oryza sativa L. ssp. japonica).

  2002cited by this paper
• The Ensembl genome database project

  2002cited by this paper
• Genes on human chromosome 19 show extreme divergence from the mouse orthologs and a high GC content.

  2002cited by this paper
• Mutations of the BRAF gene in human cancer

  2002cited by this paper
• Multifactorial genetics: Mapping and analysis of quantitative trait loci in experimental populations

  2002cited by this paper
• Obox, a family of homeobox genes preferentially expressed in germ cells.

  2002cited by this paper
• The complex history of a gene proposed to participate in a sexual isolation mechanism in house mice.

  2002cited by this paper
• Prolactin: the new biology of an old hormone.

  2002cited by this paper
• HGVbase: a human sequence variation database emphasizing data quality and a broad spectrum of data sources

  2002cited by this paper
• Human chromosome 21 gene expression atlas in the mouse

  2002cited by this paper
• Function and genetics of dystrophin and dystrophin-related proteins in muscle.

  2002cited by this paper
• Mutation rates in mammalian genomes

  2002cited by this paper
• A Comparison of Whole-Genome Shotgun-Derived Mouse Chromosome 16 and the Human Genome

  2002cited by this paper
• Deterministic mutation rate variation in the human genome.

  2002cited by this paper
• A high-resolution recombination map of the human genome

  2002cited by this paper
• Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

  2002cited by this paper
• Human SNP variability and mutation rate are higher in regions of high recombination.

  2002cited by this paper
• Comparative developmental anatomy of the murine and human definitive placentae.

  2002cited by this paper
• The mouse: genetics meets behaviour

  2002cited by this paper
• Recent Segmental Duplications in the Human Genome

  2002cited by this paper
• Large-Scale Transcriptional Activity in Chromosomes 21 and 22

  2002cited by this paper
• Mutation of melanosome protein RAB38 in chocolate mice

  2002cited by this paper
• rVista for comparative sequence-based discovery of functional transcription factor binding sites.

  2002cited by this paper
• A Draft Sequence of the Rice Genome (Oryza sativa L. ssp. japonica)

  2002cited by this paper
• Minireview Computational Genomics of Noncoding RNA Genes

  2002cited by this paper
• Genome-scale evolution: reconstructing gene orders in the ancestral species.

  2002cited by this paper
• Ca(2+)-independent but voltage-dependent secretion in mammalian dorsal root ganglion neurons.

  2002cited by this paper
• Genomic divergence between human and chimpanzee estimated from large-scale alignments of genomic sequences.

  2001cited by this paper
• A predictive model for regulatory sequences directing liver-specific transcription.

  2001cited by this paper
• Parallel adaptive radiations in two major clades of placental mammals

  2001cited by this paper
• Functional annotation of a full-length mouse cDNA collection

  2001cited by this paper
• Expression and phylogeny of claudins in vertebrate primordia

  2001cited by this paper
• Molecular phylogenetics and the origins of placental mammals

  2001cited by this paper
• Human Chromosome 19 and Related Regions in Mouse: Conservative and Lineage-Specific Evolution

  2001cited by this paper
• The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men

  2001cited by this paper
• CGH, cDNA and Tissue Microarray Analyses Implicate FGFR2 Amplification in a Small Subset of Breast Tumors

  2001cited by this paper
• Integrating genomic homology into gene structure prediction

  2001cited by this paper
• Insertional polymorphisms of full-length endogenous retroviruses in humans.

  2001cited by this paper
• Of mice and genome sequence.

  2001cited by this paper
• SGP-1: prediction and validation of homologous genes based on sequence alignments.

  2001cited by this paper
• Sequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/Fhit

  2001cited by this paper
• Sequence variation and disease in the wake of the draft human genome.

  2001cited by this paper
• Creating the Gene Ontology Resource : Design and Implementation The Gene Ontology Consortium 2

  2001cited by this paper
• Recombineering: a powerful new tool for mouse functional genomics

  2001cited by this paper
• The sequence of the human genome (abstract only)

  2001cited by this paper
• Evidence for genomic rearrangements mediated by human endogenous retroviruses during primate evolution

  2001cited by this paper
• Estimation of divergence times from multiprotein sequences for a few mammalian species and several distantly related organisms

  2001cited by this paper
• Design of a compartmentalized shotgun assembler for the human genome

  2001cited by this paper
• FEMALE PREFERENCE FOR MALE SALIVA: IMPLICATIONS FOR SEXUAL ISOLATION OF MUS MUSCULUS SUBSPECIES

  2001cited by this paper
• Single nucleotide polymorphisms and recombination rate in humans.

  2001cited by this paper
• InterProScan - an integration platform for the signature-recognition methods in InterPro

  2001cited by this paper
• Identification of two rodent genes encoding homologues to seminal vesicle autoantigen: a gene family including the gene for prolactin-inducible protein.

  2001cited by this paper
• A comparison of the Celera and Ensembl predicted gene sets reveals little overlap in novel genes.

  2001cited by this paper

• Metabolic dysfunction-associated steatotic liver disease and steatohepatitis-associated hepatocarcinoma preclinical models.

  2026cites this paper
• Animal models of hypoplastic left heart syndrome: genetic and anatomical approaches.

  2026cites this paper
• Advances in the diagnosis and treatment of oligoasthenozoospermia based on epigenetic regulation

  2026cites this paper
• Intermittent Propofol Exposure Induces Neurodevelopmental Alterations in Human Brain Organoids

  2026cites this paper
• Repeated adenosine A1 receptor antagonism rewires ventral hippocampus-ventral tegmental area transmission and enhances stress-coping responses.

  2026cites this paper
• Challenges and Opportunities in Multi-Omics Data Acquisition and Analysis: Toward Integrative Solutions.

  2026cites this paper
• SIRT5 Induces Tubulointerstitial Fibrosis via GLS1 in Diabetic Nephropathy.

  2026cites this paper
• From exposure models to multi-organ toxicity of 6PPD-quinone in mice: A mini-review.

  2026cites this paper
• Expression of endogenous retroviral elements is associated with extracellular matrix remodeling in prostate cancer

  2026cites this paper
• Chromosome length is constrained by spindle scaling to ensure faithful mitosis in mammals.

  2026cites this paper
• Genome variations reveal rapid adaptation to domestication and habitat changes in the brown algae Saccharina japonica.

  2026cites this paper
• Acute testicular hyperthermia leads to rapid loss of global piRNA and a concurrent increase in LINE1 activity within heat sensitive male germ cells

  2026cites this paper
• PRPF8 Mutation-Induced Defects in Human iPSC-Derived RPE Are Rescued by Adenine Base Editing

  2026cites this paper
• Fifteen years of the Diversity Outbred mouse model: a review

  2026cites this paper
• Diversity of Integration Sites of Bovine Leukemia Virus (BLV) and Roles of Genes Related to Development of BLV-Induced Lymphoma in a Large Cohort

  2026cites this paper
• Association of tumour-associated macrophage states with non-conserved lncrnas in lung cancer.

  2026cites this paper
• Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice

  2026cites this paper
• Endogenous Metabolic Incorporation of Inhaled Soot Particles Revealed by Bottom-up 13C Labeling.

  2026cites this paper
• 4D multimodal wound healing atlas reveals organ-level controls of repair phase transitions

  2026cites this paper
• A scalable two-step genome editing strategy for generating full-length gene-humanized mice at diverse genomic loci

  2026cites this paper
• Functional analysis of two uncharacterized genes, C130074G19Rik and I830077J02Rik, during early haematopoietic development.

  2026cites this paper
• A comprehensive N-glycoproteome atlas reveals tissue-specific glycan remodeling but non-random structural microheterogeneities

  2026cites this paper
• Topological Approaches in Animal Comparative Genomics.

  2026cites this paper
• Design of a Head Position and Orientation Detection System Based on Improved Markerless Visual Tracking for Unrestrained Awake Mice

  2025cites this paper
• Murine model for investigating severe trauma.

  2025cites this paper
• LINE-1 transposition into murine Thyroglobulin results in congenital thyroid dysplasia

  2025cites this paper
• Mouse metastable epialleles are extremely rare

  2025cites this paper
• Genetic Diseases of Fucosylation: Insights from Model Organisms

  2025cites this paper
• Forced expression of MSR repeat transcripts above a threshold limit breaks heterochromatin organisation

  2025cites this paper
• Body ownership: A cephalopod has a sense of self.

  2025cites this paper
• Epigenetic and experimental approaches influencing non-coding RNAs.

  2025cites this paper
• Nanoneedles enable spatiotemporal lipidomics of living tissues

  2025cites this paper
• Establishment of Dental Pulp Cell Culture System for Analyzing Dentinogenesis in Mouse Incisors

  2025cites this paper
• Sigma‑2 Receptor/Transmembrane Protein 97 in Pain Modulation: Tracing Historical Roots and Current Research Directions.

  2025cites this paper
• Gene therapy advances using canine and feline animal models of inherited retinal degeneration

  2025cites this paper
• Research progress in high-throughput DNA synthesis and its applications.

  2025cites this paper
• Effect of Mouse (Mus musculus) Sex and C57BL/6 Substrain on Sensitivity to Isoflurane and Ketamine-Xylazine-Acepromazine Anesthesia.

  2025cites this paper
• Genetically engineered mouse models in gastric precancerous lesions research

  2025cites this paper
• The CpG Landscape of Protein Coding DNA in Vertebrates

  2025cites this paper
• Mouse Models of HIV-Associated Atherosclerosis

  2025cites this paper
• Myelin regulatory factor (MYRF) is a critical early regulator of retinal pigment epithelial development

  2025cites this paper
• Three-Dimensional Culture Systems in Neuroblastoma Research

  2025cites this paper
• Functional profiling of KCNE1 variants informs population carrier frequency of Jervell and Lange-Nielsen syndrome type 2

  2025cites this paper
• Building better genome annotations across the tree of life

  2025cites this paper
• Positive-Negative Selection: The Counterselection Breakthrough that Conventionalized Reverse Genetics in the Mouse.

  2025cites this paper
• A genome-scale CRISPR deletion screen in Chinese Hamster Ovary cells reveals essential regions of the coding and non-coding genome

  2025cites this paper
• The landscape of fitness effects of putatively functional noncoding mutations in humans

  2025cites this paper
• A review of the efficacy of clinical tuberculosis vaccine candidates in mouse models

  2025cites this paper
• Slow-Timescale Regulation of Dopamine Release and Mating Drive Over Days

  2025cites this paper
• Memories of the Human Genome Project at the Sanger Centre.

  2025cites this paper
• Selection signatures in Gir and Holstein cattle.

  2025cites this paper
• CSLAN: Cross-Species Latent Alignment Network for Trauma-Related Cell-Type Classification

  2025cites this paper
• Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

  2025cites this paper
• Insights from human NF-κB knockouts

  2025cites this paper
• Preclinical models in the study of lymph node metastasis

  2025cites this paper
• LINE-1 retrotransposon activation drives age-associated inflammation via cytoplasmic cDNA-STING/type I interferon signalling: therapeutic potential of reverse transcriptase inhibition

  2025cites this paper
• Neurological Tissue Dissection Techniques in Mouse Models for Reproducible Scientific Results: Brain, Spinal Cord, CSF, and Sciatic Nerve

  2025cites this paper
• Clinical Characteristics of Women With Chest Pain: Men From Mars, Women From Venus

  2025cites this paper
• Intramolecular Epistatic Interactions in Genetic Diseases

  2025cites this paper
• Dual roles of N6-methyladenosine in R-loop regulation of gene transcription and genome stability

  2025cites this paper
• Evolution of endogenous retroviruses (ERVs) in the Bovinae subfamily.

  2025cites this paper
• Evaluation and application analysis of animal models of PIPNP based on data mining

  2025cites this paper
• Systematic revelation and meditation on the significance of long exons using representative eukaryotic genomes

  2025cites this paper
• AGO2 slicing of a domesticated retrotransposon is necessary for normal vasculature development

  2025cites this paper
• Intact, recombinant, and spliced forms of endogenous mouse mammary tumor viruses in inbred and wild mice

  2025cites this paper
• GrimACE: Automated, multimodal cage-side assessment of pain and well-being in mice

  2025cites this paper
• Innate Immunity and Asthma Exacerbations: Insights From Human Models

  2025cites this paper
• Translating animal models of SARS-CoV-2 infection to vascular, neurological and gastrointestinal manifestations of COVID-19

  2025cites this paper
• Gfi1 controls the formation of effector-like CD8+ T cells during chronic infection and cancer

  2025cites this paper
• Computational modeling of human genetic variants in mice

  2025cites this paper
• Alternative Splicing as a Modulator of the Interferon-Gamma Pathway

  2025cites this paper
• Transposon-host arms race: a saga of genome evolution.

  2025cites this paper
• An Exploratory Genomic and Transcriptomic Analysis Between Choloepus didactylus and Homo sapiens

  2025cites this paper
• Expression of LINE-1 elements is required for preimplantation development and totipotency

  2025cites this paper
• 20 years of stemness: From stem cells to hypertranscription and back

  2025cites this paper
• A genome-wide study of ruminants uncovers two endogenous retrovirus families recently active in goats

  2025cites this paper
• Asymmetric sampling in time: evidence and perspectives.

  2025cites this paper
• Development of an intranodal drug delivery system using a mouse model with lymphadenopathy: novel discoveries and clinical application

  2025cites this paper
• Insights into Virus-Host Interactions: Lessons from Caenorhabditis elegans-Orsay Virus Model

  2025cites this paper
• Activation of endogenous retroviruses characterizes the maternal-fetal interface in the BTBR mouse model of autism spectrum disorder

  2025cites this paper
• Exon-intron boundary detection made easy by physicochemical properties of DNA.

  2025cites this paper
• KRAB zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptomes and genome evolution

  2025cites this paper
• Generation of a Ym1 deficient mouse utilising CRISPR-Cas9 in CB6 embryos

  2025cites this paper
• Role of lncRNAs related to NRs in the regulation of gene expression

  2025cites this paper
• OpenSpliceAI: An efficient, modular implementation of SpliceAI enabling easy retraining on non-human species

  2025cites this paper
• Detection of central and obstructive sleep apneas in mice: A new surgical and recording protocol

  2025cites this paper
• Phenogenomic resources immortalized in a panel of wild-derived strains of five species of house mice

  2025cites this paper
• Optimization of 3D Extrusion-Printed Particle-Containing Hydrogels for Osteogenic Differentiation

  2025cites this paper
• Advances in Detection Methods for A‐to‐I RNA Editing

  2025cites this paper
• Single cell spatial proteomics maps human liver zonation patterns and their vulnerability to fibrosis

  2025cites this paper
• Establishing genome sequencing and assembly for non-model and emerging model organisms: a brief guide

  2025cites this paper
• Zygotic activation of transposable elements during zebrafish early embryogenesis

  2025cites this paper
• Ultrasound guidance for intervertebral disc location and paravertebral tissue swelling quantification in a mouse model of intervertebral disc herniation

  2025cites this paper
• Quantifying Hierarchical Conflicts in Homology Statements

  2025cites this paper
• The mouse pangenome reveals the structural complexity of the murine protein-coding landscape

  2025cites this paper
• Biochemical and hematological reference intervals in rhesus and cynomolgus macaques and implications for vaccine and drug development

  2025cites this paper
• MORE-RNAseq: a pipeline for quantifying retrotransposition-capable LINE1 expression based on RNA-seq data

  2025cites this paper
• The impact of micro- and nanoplastics on immune system development and functions: Current knowledge and future directions.

  2025cites this paper
• Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary sex classification of somatic tissues

  2025cites this paper
• Male reproductive phenotype alterations in heterozygous β-globin gene knockout thalassemia (BKO) mice as a model for β-thalassemia patients

  2025cites this paper