Macrophages retain hematopoietic stem cells in the spleen via VCAM-1

Dutta et al. show that targeting VACM-1 expression in splenic macrophages impairs extramedullary hematopoiesis, thus reducing inflammation in mouse ischemic heart and atherosclerotic plaques.

• Publication year

  2015

• Venue

  Journal of Experimental Medicine

• Publication date

  2015-04-06

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/jem.20141642PMID 25800955PMCID 4387283
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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