Exposure to DEHP and MEHP from hatching to adulthood causes reproductive dysfunction and endocrine disruption in marine medaka (Oryzias melastigma).

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Aquatic Toxicology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.aquatox.2013.10.025PMID 24292025
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Endocrine disruption by di‐(2‐ethylhexyl)‐phthalate in Chinese rare minnow (Gobiocypris rarus)

  2013cited by this paper
• Whole spectrum of cytochrome P450 genes and molecular responses to water-accommodated fractions exposure in the marine medaka.

  2013cited by this paper
• Assay of vtg, ERs and PPARs as endpoint for the rapid in vitro screening of the harmful effect of Di-(2-ethylhexyl)-phthalate (DEHP) and phthalic acid (PA) in zebrafish primary hepatocyte cultures.

  2013cited by this paper
• Deep sequencing-based transcriptome profiling analysis of Oryzias melastigma exposed to PFOS.

  2012cited by this paper
• Transcriptional responses of the brain-gonad-liver axis of fathead minnows exposed to untreated and ozone-treated oil sands process-affected water.

  2012cited by this paper
• PFOS elicits transcriptional responses of the ER, AHR and PPAR pathways in Oryzias melastigma in a stage-specific manner.

  2012cited by this paper
• A mixture of an environmentally realistic concentration of a phthalate and herbicide reduces testosterone in male fathead minnow (Pimephales promelas) through a novel mechanism of action.

  2012cited by this paper
• Effect of mono-(2-ethylhexyl) phthalate on human and mouse fetal testis: In vitro and in vivo approaches.

  2012cited by this paper
• Evaluation of ovarian toxicity of mono-(2-ethylhexyl) phthalate (MEHP) using cultured rat ovarian follicles.

  2012cited by this paper
• Phthalates exposure of Chinese reproductive age couples and its effect on male semen quality, a primary study.

  2012cited by this paper
• Effects of the UV-filter 2-ethyl-hexyl-4-trimethoxycinnamate (EHMC) on expression of genes involved in hormonal pathways in fathead minnows (Pimephales promelas) and link to vitellogenin induction and histology.

  2011cited by this paper
• Salinity influences glutathione S-transferase activity and lipid peroxidation responses in the Crassostrea gigas oyster exposed to diesel oil.

  2011cited by this paper
• Molecular staging of marine medaka: a model organism for marine ecotoxicity study.

  2011cited by this paper
• A twenty-volunteer study using deuterium labelling to determine the kinetics and fractional excretion of primary and secondary urinary metabolites of di-2-ethylhexylphthalate and di-iso-nonylphthalate.

  2011cited by this paper
• Transcriptional responses in Japanese medaka (Oryzias latipes) exposed to binary mixtures of an estrogen and anti-estrogens.

  2011cited by this paper
• Urinary di‐(2‐ethylhexyl)phthalate metabolites in athletes as screening measure for illicit blood doping: a comparison study with patients receiving blood transfusion

  2010cited by this paper
• Insulin-like Growth Factors and Fish Reproduction

  2010cited by this paper
• Bioaccumulation of perfluorochemicals in Pacific oyster under different salinity gradients.

  2010cited by this paper
• Mechanisms of toxicity of di(2-ethylhexyl) phthalate on the reproductive health of male zebrafish.

  2010cited by this paper
• DEHP Impairs Zebrafish Reproduction by Affecting Critical Factors in Oogenesis

  2010cited by this paper
• Toxicity of seven phthalate esters to embryonic development of the abalone Haliotis diversicolor supertexta

  2009cited by this paper
• Ultra-trace determination of phthalate ester metabolites in seawater, sediments, and biota from an urbanized marine inlet by LC/ESI-MS/MS.

  2009cited by this paper
• Rapid adaptation of molecular resources from zebrafish and medaka to develop an estuarine/marine model.

  2009cited by this paper
• Endocrine Disruption in Aquatic Vertebrates

  2009cited by this paper
• Endocrine/paracrine control of zebrafish ovarian development.

  2009cited by this paper
• Development of a marine fish model for studying in vivo molecular responses in ecotoxicology.

  2008cited by this paper
• Tissue and sexually dimorphic expression of ovarian and brain aromatase mRNA in the Japanese medaka (Oryzias latipes): implications for their preferential roles in ovarian and neural differentiation and development.

  2008cited by this paper
• Estrogenic activity and reproductive effects of the UV-filter oxybenzone (2-hydroxy-4-methoxyphenyl-methanone) in fish.

  2008cited by this paper
• Non-monotonic dose-response relationship in steroid hormone receptor-mediated gene expression.

  2007cited by this paper
• Expression of IGF-I and IGF-I receptor in male and female sterlet, Acipenser ruthenus--evidence for an important role in gonad maturation.

  2007cited by this paper
• Gene expression profiles revealing the mechanisms of anti-androgen- and estrogen-induced feminization in fish.

  2007cited by this paper
• Occurrence and air$/$sea-exchange of novel organic pollutants in the marine environment

  2006cited by this paper
• A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl)-phthalate (DEHP): non-monotonic dose-response and low dose effects on rat brain aromatase activity.

  2006cited by this paper
• Multiple molecular effect pathways of an environmental oestrogen in fish.

  2006cited by this paper
• Effects of 4-tert-pentylphenol on the gene expression of P450 11beta-hydroxylase in the gonad of medaka (Oryzias latipes).

  2005cited by this paper
• Evaluation of anti-androgenic activity of di-(2-ethylhexyl)phthalate.

  2005cited by this paper
• ESTIMATED EXPOSURE TO PHTHALATES IN COSMETICS AND RISK ASSESSMENT

  2004cited by this paper
• Effects of endocrine disrupters on sex steroid synthesis and metabolism pathways in fish.

  2004cited by this paper
• Nonmonotonic dose-response relationships: mechanistic basis, kinetic modeling, and implications for risk assessment.

  2004cited by this paper
• Effects of 17alpha-ethinylestradiol in a fathead minnow (Pimephales promelas) gonadal recrudescence assay.

  2004cited by this paper
• Effects of bis(2-ethylhexyl) phthalate and benzo[a]pyrene on the embryos of Japanese medaka (Oryzias latipes).

  2004cited by this paper
• Effects of bis(2-ethylhexyl) phthalate, γ-hexachlorocyclohexane, and 17β-estradiol on the fry stage of medaka (Oryzias latipes).

  2004cited by this paper
• Di(2-ethylhexyl)phthalate (DEHP) metabolites in human urine and serum after a single oral dose of deuterium-labelled DEHP

  2004cited by this paper
• Endocrine-disrupting effects of cattle feedlot effluent on an aquatic sentinel species, the fathead minnow.

  2003cited by this paper
• Analysis of zebrafish cyp19 promoters.

  2003cited by this paper
• Inhibition of oocyte development in Japanese medaka (Oryzias latipes) exposed to di-2-ethylhexyl phthalate.

  2002cited by this paper
• Sexually dimorphic expression of steroidogenic factor 1 (SF-1) in developing gonads of the American bullfrog, Rana catesbeiana.

  2002cited by this paper
• Effects of ethynylestradiol on the reproductive physiology in zebrafish (Danio rerio): Time dependency and reversibility

  2002cited by this paper
• Monitoring of phthalic acid monoesters in river water by solid-phase extraction and GC-MS determination.

  2001cited by this paper
• Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

  2001cited by this paper
• Differential tissue distribution, developmental programming, estrogen regulation and promoter characteristics of cyp19 genes in teleost fish.

  2001cited by this paper
• Development of a Reproductive Performance Test for Endocrine Disrupting Chemicals Using Pair-Breeding Fathead Minnows (Pimephales promelas)

  2000cited by this paper
• Effects of waterborne exposure of 17 β-estradiol on secondary sex characteristics and gonads of fathead minnows (Pimephales promelas)

  1999cited by this paper
• The environmental fate of phthalate esters: A literature review

  1997cited by this paper
• Insulin‐like growth factor (IGF‐I) mRNA and IGF‐I receptor in trout testis and in isolated spermatogenic and Sertoli cells

  1996cited by this paper
• Biotransformation of di(2‐ethylhexyl)phthalate by rainbow trout

  1995cited by this paper
• Phthalate ester plasticizers: a new class of marine pollutant.

  1978cited by this paper
• Metabolism and tissue distribution of mono-2-ethylhexyl phthalate in the rat.

  1978cited by this paper
• Toxicity, residue dynamics, and reproductive effects of phthalate esters in aquatic invertebrates.

  1973cited by this paper
• Phthalate ester residues--their metabolism and analysis in fish.

  1973cited by this paper

• Di-(2-Ethylhexyl) phthalate causes testicular ferroptosis though deficiency of androgen receptor and disruption of mitochondrial quality control.

  2026cites this paper
• Toxicological implications of emerging pollutants on aquatic organisms

  2026cites this paper
• Interactions of phthalate plasticizers with model stratum corneum lipid matrix. Langmuir monolayer and X-ray diffraction studies

  2026cites this paper
• Multibiomarker assessment in the microalgae Isochrysis zhanjiangensis exposed to di-(2-ethylhexyl) phthalate

  2025cites this paper
• Are Microplastic (∼25–1000 μm) and Plasticizer Concentrations Correlated in Sediments of an Urbanized UK Estuary?

  2025cites this paper
• Di(2-ethylhexyl) Phthalate Alters Primordial Germ Cell Distribution and the Reproductive Neuroendocrine Regulatory Axis in Zebrafish Embryos

  2025cites this paper
• Influence of Methomyl and Salinity on the Freshwater Snail Physa venustula: Egestion, Movement, and Hydration Index

  2025cites this paper
• Toxicological impacts of microplastic fibers: A review assessing risk to human and aquatic health

  2025influential citation
• Endocrine Disrupting Agents: Toxicological Aspects on Male Reproduction

  2025cites this paper
• Embryonic exposure to the WAF of crude oil impairs male Oryzias melastigma reproduction and the mechanism involved.

  2025cites this paper
• Transcriptomic Analysis Reveals Developmental Toxicity Induced by Environmentally Relevant Concentrations of Fenvalerate and Sulfamethoxazole in Embryo and Juvenile Marine Medaka (Oryzias melastigma, McClelland, 1839)

  2025cites this paper
• Comparing phthalate exposure between bottlenose dolphins (Tursiops truncatus) residing in urban and rural environments

  2025cites this paper
• Non‐Phthalate Plasticizer Bis(2‐ethylhexyl) Sebacate Induces Testis‐Ova Formation and Suppresses Reproduction in Japanese Medaka

  2025cites this paper
• Mangrove consortium resistant to the emerging contaminant DEHP: Composition, diversity, and ecological function of bacteria

  2025cites this paper
• Recent advances on photocatalytic degradation of phthalate ester plasticizers using nanomaterial photocatalysts.

  2025cites this paper
• Ecotoxicological effects of soft plastic fishing lures on the benthic amphipod Hyalella azteca

  2025cites this paper
• Phthalic acid esters as an ecological hazard to the coral reef ecosystems: A case study from the coral reef waters of the Lakshadweep Archipelago, Arabian Sea.

  2025cites this paper
• Chronic paternal or maternal exposure to florfenicol causes reproductive and developmental toxicity in marine medaka (Oryzias melastigma).

  2025cites this paper
• Silent Disruptors: The Multifaceted Impact of Phthalates Across Aquatic Invertebrate and Vertebrate Taxa

  2025cites this paper
• Di(2-ethylhexyl) phthalate disrupts circadian rhythm associated with changes in metabolites and cytochrome P450 gene expression in Caenorhabditis elegans.

  2024cites this paper
• Sources and fates of NO3- and PO43- in an alluvial plain wetland - Insights from the Auzon oxbow and the alluvial aquifer of the Allier (Auvergne, France)

  2024cites this paper
• Exposure of endocrine disruptive phthalates from fruit juices packed in plastic bottles and their risk assessment in Pakistan

  2024cites this paper
• Plastic additives affect estrogenic pathways and lipid metabolism in precision - cut - liver slices in Atlantic cod (Gadus morhua).

  2024cites this paper
• Exposure to environmentally relevant concentrations of di-(2-ethylhexyl) phthalate (DEHP) induced reproductive toxicity in female koi carp (Cyprinus carpio).

  2024cites this paper
• Early-life exposure to di(2-ethylhexyl) phthalate impairs reproduction in adult female zebrafish (Danio rerio).

  2024cites this paper
• MEHP induced mitochondrial damage by promoting ROS production in CIK cells, leading to apoptosis, autophagy, cell cycle arrest.

  2024cites this paper
• Combined effects and potential mechanisms of phthalate metabolites on serum sex hormones among reproductive-aged women: An integrated epidemiology and computational toxicology study.

  2024cites this paper
• Pollution Characterization, Ecological Risks and Human Exposure to Phthalates in the Environment

  2024cites this paper
• Phthalate ester and cholesterol profiles of blubber samples of the free-ranging Amazon River dolphin (Cetacea: Iniidae: Inia geoffrensis) in the Brazilian Amazon.

  2024cites this paper
• Occurrence of plastic additives in coral-reef invertebrates on natural and plastic substrates.

  2024cites this paper
• Exposure to environmental doses of DEHP causes phenotypes of polycystic ovary syndrome.

  2024cites this paper
• Phthalates released from microplastics can't be ignored: Sources, fate, ecological risks, and human exposure risks

  2024cites this paper
• Embryonic exposure to water accommodated fraction of crude oil inhibits reproductive capability in adult female marine medaka (Oryzias melastigma).

  2024cites this paper
• Thyroid and neurobehavioral effects of DiNP on GH3 cells and larval zebrafish (Danio rerio).

  2024cites this paper
• Toxicity assessment of di(2-ethylhexyl) phthalate using zebrafish embryos: Cardiotoxic potential.

  2024cites this paper
• Phthalate esters and nonylphenols in fractionated marine harbor phytoplankton and concentrations of microplastics in seawater

  2024cites this paper
• Thyroid and sex hormone disrupting effects of DEHTP at different life stages of zebrafish (Danio rerio).

  2024cites this paper
• Exposure to Plasticiser DEHP Affects Eggs Spawned by Blue Mussels: A Possible Risk to Fertilisation?

  2024influential citation
• Effect of diisobutyl adipate on the expression of biomarker genes that respond to endocrine disruption and on gonadal sexual differentiation in Japanese medaka (Oryzias latipes).

  2024cites this paper
• High production volume chemicals in the most consumed seafood species in Tarragona area (Spain): Occurrence, exposure, and risk assessment.

  2023cites this paper
• Chromatin modifiers: A new class of pollutants with potential epigenetic effects revealed by in vitro assays and transcriptomic analyses.

  2023cites this paper
• Recent advances in remediation strategies for mitigating the impacts of emerging pollutants in water and ensuring environmental sustainability.

  2023cites this paper
• Evaluation of precopulatory pairing behaviour and male fertility in a marine amphipod exposed to plastic additives.

  2023cites this paper
• Emerging and legacy plasticisers in coastal and estuarine environments: A review.

  2023cites this paper
• Influence of phthalate and non-phthalate plasticizers on reproductive endocrine system-related gene expression profiles in Japanese medaka (Oryzias latipes)

  2023cites this paper
• Physiological impact of personal care product constituents on non-target aquatic organisms.

  2023cites this paper
• Effects of Di-(2-Ethylhexyl) Phthalate (DEHP) on Gamete Quality Parameters of Male Koi Carp (Cyprinus carpio)

  2023cites this paper
• Weathering alters the profile of trace metals and organic compounds in leachates and bioavailability extracts from microplastics of trail running shoes.

  2023cites this paper
• Endocrine disruptor responses in the embryos of marine medaka (Oryzias melastigma) after exposure to aged plastic leachates.

  2023cites this paper
• Phthalate induced hormetic effect reveals susceptibility of gill compared to muscle tissue after depuration in commercially important fish (Etroplus suratensis).

  2023cites this paper
• Impact of Metabolic disrupting chemicals on redox homeostasis, energy sensors, receptor modulation, and hormone metabolism: A comparative account in Teleost and mammalian model organisms

  2023cites this paper
• Contaminants and their ecological risk assessment in beach sediments and water along the Maharashtra coast of India: A comprehensive approach using microplastics, heavy metal(loid)s, pharmaceuticals, personal care products and plasticizers.

  2023cites this paper
• Effects of di-(2-ethylhexyl) terephthalate on hypothalamus-pituitary-gonad axis in adult zebrafish.

  2023cites this paper
• Impact of acetyl tributyl citrate on gonadal sex differentiation and expression of biomarker genes for endocrine disruption in Japanese medaka.

  2023cites this paper
• Chronic diflubenzuron exposure causes reproductive toxic effects in female marine medaka (Oryzias melastigma).

  2023cites this paper
• Seafood consumption as a source of exposure to high production volume chemicals: A comparison between catalonia and the Canary Islands.

  2023cites this paper
• Role of COX-2/PGE2 signaling pathway in the apoptosis of rat ovarian granulosa cells induced by MEHP.

  2023cites this paper
• Reproductive toxicity in marine medaka (Oryzias melastigma) due to embryonic exposure to PCB 28 or 4'-OH-PCB 65.

  2023cites this paper
• Long-term tralopyril exposure results in endocrinological and transgenerational toxicity: A two-generation study of marine medaka (Oryzias melastigma).

  2023cites this paper
• Impacts of di-(2-ethylhexyl) phthalate on Folsomia candida (Collembola) assessed with a multi-biomarker approach.

  2022cites this paper
• Concentrations of phthalate esters on Indian Ocean silky sharks and their long-term dietary consumption risks

  2022cites this paper
• Evaluating the alterations of the estrogen-responsive genes in Cyprinodon variegatus larvae for biomonitoring the impacts of estrogenic endocrine disruptors (EEDs).

  2022cites this paper
• Bisphenol A alters sexual dimorphism and gene expression in marine medaka Oryzias melastigma

  2022cites this paper
• Thyroid hormone disruption by bis-(2-ethylhexyl) phthalate (DEHP) and bis-(2-ethylhexyl) adipate (DEHA) in Japanese medaka Oryzias latipes.

  2022cites this paper
• Effects of bisphenol AF on growth, behavior, histology and gene expression in marine medaka (Oryzias melastigma).

  2022cites this paper
• Release of phthalate esters (PAEs) and microplastics (MPs) from face masks and gloves during the COVID-19 pandemic

  2022cites this paper
• Norethindrone alters growth, sex differentiation and gene expression in marine medaka (Oryzias melastigma)

  2022cites this paper
• Plastic additive di(2-ethylhexyl)phthalate (DEHP) causes cell death and micronucleus induction on a bottlenose dolphin’s (Tursiops truncatus) in vitro-exposed skin cell line

  2022cites this paper
• Aquatic and human health risk assessment of Humanogenic Emerging Contaminants (HECs), Phthalate Esters from the Indian Rivers.

  2022cites this paper
• Micro-contaminant, but immense impact: Source and influence of diethyl phthalate plasticizer on bottom-dwelling fishes.

  2022cites this paper
• Kinetic Modelling of the Photocatalytic Degradation of Diisobutyl Phthalate and Coupling with Acoustic Cavitation

  2022cites this paper
• A Novel Ex Vivo Approach Based on Proteomics and Biomarkers to Evaluate the Effects of Chrysene, MEHP, and PBDE-47 on Loggerhead Sea Turtles (Caretta caretta)

  2022cites this paper
• Species Persistence with Hybridization in Toad-Headed Lizards Driven by Divergent Selection and Low Recombination

  2022cites this paper
• Long-term exposure of the Mediterranean mussels, Mytilus galloprovincialis to polyethylene terephthalate microfibers: Implication for reproductive and neurotoxic effects.

  2022cites this paper
• Phthalate esters in marine ecosystems: analytical methods, occurrence and distribution

  2022cites this paper
• Four plastic additives reduce larval growth and survival in the sea urchin Strongylocentrotus purpuratus.

  2022cites this paper
• Hazards of phthalates (PAEs) exposure: A review of aquatic animal toxicology studies.

  2021cites this paper
• Seasonal distribution and ecological risks of phthalic acid esters in surface water of Taihu Lake, China.

  2021cites this paper
• Size-dependent adverse effects of microplastics on intestinal microbiota and metabolic homeostasis in the marine medaka (Oryzias melastigma).

  2021cites this paper
• In vitro evaluation of cytotoxic effects of di (2-ethylhexyl) phthalate (DEHP) produced by Bacillus velezensis strain RP137 isolated from Persian Gulf.

  2021cites this paper
• Reproductive toxicity and underlying mechanisms of di(2-ethylhexyl) phthalate in nematode Caenorhabditis elegans.

  2021cites this paper
• Rapid in-situ analysis of phthalates in face masks by desorption corona beam ionization tandem mass spectrometry.

  2021cites this paper
• Can phthalates move into the eggs of the loggerhead sea turtle Caretta caretta? The case of the nests on the Linosa Island in the Mediterranean Sea.

  2021cites this paper
• Evaluation of reproductive hormones in Egyptian workers occupationally exposed to di-2-ethylhexyl phthalate (DEHP): a cross-sectional study

  2021cites this paper
• Atresia of ovarian follicles in fishes, and implications and uses in aquaculture and fisheries

  2021cites this paper
• Consequences of combined exposure to thermal stress and the plasticiser DEHP in Mytilus spp. differ by sex.

  2021cites this paper
• Insights Into the Prevalence and Impacts of Phthalate Esters in Aquatic Ecosystems

  2021cites this paper
• The Effects of Endocrine Disruptors on Fish

  2021cites this paper
• Effects of endocrine disrupting chemicals on gonad development: Mechanistic insights from fish and mammals.

  2021cites this paper
• Endocrine disruption of pharmaceuticals on marine organisms: Thyroidal, gonadotrophic, and behavioral responses

  2021cites this paper
• Targeted and non-targeted analysis of young-of-year smallmouth bass using comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry.

  2021cites this paper
• Long-term chronic exposure to di-(2-ethylhexyl)-phthalate induces obesity via disruption of host lipid metabolism and gut microbiota in mice.

  2021cites this paper
• Di(2-ethylhexyl) phthalate (DEHP) and thyroid: biological mechanisms of interference and possible clinical implications

  2021cites this paper
• Phthalic Acid Esters Increased Activation of Urease by Altering the Molecular Conformation

  2021cites this paper
• Regulation of TRAF6 by MicroRNA-146a in Zebrafish Embryos after Exposure to Di(2-Ethylhexyl) Phthalate at Different Concentrations.

  2021cites this paper
• Reality Check: Experimental Studies on Microplastics Lack Realism

  2021cites this paper
• Aging of microplastics and their role as vector for copper in aqueous solution

  2021cites this paper
• Transient exposure to environmentally realistic concentrations of di-(2-ethylhexyl)-phthalate during sensitive windows of development impaired larval survival and reproduction success in Japanese medaka

  2020cites this paper
• Effects of DEHP on the ecdysteroid pathway, sexual behavior and offspring of the moth Spodoptera littoralis.

  2020cites this paper
• Occurrence of phthalic acid esters in sediment samples from East China Sea.

  2020cites this paper