Implications of the Blood-Brain Barrier and Its Manipulation

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Springer US

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1007/978-1-4613-0701-3
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• THE DIRECT DEMONSTRATION OF A BARRIER MECHANISM IN THE BRAIN CAPILLARIES.

  2009influential reference
• Prostaglandins and leukotrienes.

  1989cited by this paper
• Pharmacology of the Blood-Brain Barrier

  1989cited by this paper
• Strategies for drug delivery through the blood-brain barrier.

  1989cited by this paper
• Regulation of pH and HCO3 in brain and CSF of the developing mammalian central nervous system.

  1988cited by this paper
• Permeability of human brain tumor to 99mTc-gluco-heptonate and 99mTc-albumin. Implications for monoclonal antibody therapy.

  1986cited by this paper
• Blood-brain barrier: interface between internal medicine and the brain.

  1986cited by this paper
• Osmotic blood-brain barrier opening to IgM monoclonal antibody in the rat.

  1986cited by this paper
• Developments in the diagnosis and treatment of primary CNS lymphoma: A prospective series

  1986cited by this paper
• Monocytes Become Macrophages; They Do Not Become Microglia: A Light and Electron Microscopic Autoradiographic Study Using 125‐lododeoxyuridine

  1986cited by this paper
• Disorders that mimic CNS infections.

  1986cited by this paper
• [Neuropathology in acquired immune deficiency syndrome].

  1986cited by this paper
• The Effects of Brain Blood Flow on Brain Bilirubin Deposition in Newborn Piglets

  1985cited by this paper
• Osmotic blood-brain barrier modification: monoclonal antibody, albumin, and methotrexate delivery to cerebrospinal fluid and brain.

  1985cited by this paper
• Adoptive immunotherapy of intracerebral murine lymphomas: Role of different lymphoid populations

  1985cited by this paper
• Brain Bilirubin Deposition and Brain Blood Flow during Acute Urea-Induced Hyperosmolality in Newborn Piglets

  1985cited by this paper
• Clinical Significance of Esterases in Man

  1985cited by this paper
• Neuroanatomic and neurotransmitter influences on immune function.

  1985cited by this paper
• The blood-brain barrier. Transport across the cerebral endothelium.

  1985cited by this paper
• Blood–Brain Barrier Transport of Valproic Acid

  1985cited by this paper
• Adrenergic-Induced Enhancement of Brain Barrier System Permeability to Small Nonelectrolytes: Choroid Plexus versus Cerebral Capillaries

  1985cited by this paper
• Cl-HCO3 exchange in choroid plexus: analysis by the DMO method for cell pH.

  1985cited by this paper
• Autopsy findings in the acquired immune deficiency syndrome.

  1985cited by this paper
• Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer.

  1985cited by this paper
• Neural modulation of immune function.

  1985cited by this paper
• Blood pH and Brain Uptake of 14C‐Morphine

  1984cited by this paper
• Immunotherapy of cancer by systemic administration of lymphoid cells plus interleukin-2.

  1984cited by this paper
• Fracture faces of cell junctions in cerebral endothelium during normal and hyperosmotic conditions.

  1984cited by this paper
• Study of blood-brain tissue [H+] gradient during respiratory alkalosis and experimental seizures in newborn piglets. Effect on phenobarbital distribution.

  1984cited by this paper
• Effect of acidosis on bilirubin deposition in rat brain.

  1984cited by this paper
• Activated T lymphocytes produce a matrix-degrading heparan sulphate endoglycosidase

  1984cited by this paper
• Brain grafts can restore irradiation-damaged neuronal connections in newborn rats

  1984cited by this paper
• Blood-brain interfaces in vertebrates: a comparative approach.

  1984cited by this paper
• Specific adoptive immunotherapy with tumor-specific cytotoxic T-lymphocyte clone for murine malignant gliomas.

  1984cited by this paper
• Synthesis of compounds with properties of leukotrienes C4 and D4 in gerbil brains after ischemia and reperfusion.

  1984cited by this paper
• Antigen presentation: comments on its regulation and mechanism.

  1984cited by this paper
• INTRACEREBRAL ALLOTRANSPLANTATION OF PURIFIED PANCREATIC ENDOCRINE CELLS AND PANCREATIC ISLETS IN DIABETIC RATS

  1984cited by this paper
• Agarose electrophoresis and immunonephelometric quantitation of cerebrospinal fluid immunoglobulins: criteria for application in the diagnosis of neurologic disease.

  1984cited by this paper
• Ultracytochemical distribution of myelin basic protein after injection into the cerebrospinal fluid. Evidence for transport through the blood-brain barrier and binding to the luminal surface of cerebral veins.

  1984cited by this paper
• The Effects of Variations in Paco2 on Brain Blood Flow and Cardiac Output in the Newborn Piglet

  1984cited by this paper
• Differential effects of acetazolamide, benzolamide and systemic acidosis on hydrogen and bicarbonate gradients across the apical and basolateral membranes of the choroid plexus.

  1984cited by this paper
• Subacute sclerosing panencephalitis

  1983cited by this paper
• Etiology and pathogenesis of monophasic and relapsing inflammatory demyelination - human and experimental.

  1983cited by this paper
• Transport of alpha-aminoisobutyric acid across brain capillary and cellular membranes.

  1983influential reference
• Adrenergic-Receptor Mechanisms in Mammalian Choroid Plexus

  1983cited by this paper
• Immune responses in patients with brain tumors: Factors such as anti‐convulsants that may contribute to impaired cell‐mediated immunity

  1983cited by this paper
• Cellular pharmacokinetics of the phenylalanine mustards.

  1983cited by this paper
• Developmental changes in the pattern of amino acid transport at the blood-brain barrier in rats.

  1983cited by this paper
• Intrathecal IgG synthesis and blood-brain barrier impairment in patients with systemic lupus erythematosus and central nervous system dysfunction.

  1983cited by this paper
• Neuropeptides and the blood-brain barrier.

  1983cited by this paper
• Intracarotid dehydrocholate infusion: a new method for prolonged reversible blood-brain barrier disruption.

  1983cited by this paper
• Brain metabolism: a perspective from the blood-brain barrier.

  1983cited by this paper
• Increased Blood—Brain Barrier Transport of Protein-Bound Anticonvulsant Drugs in the Newborn

  1983cited by this paper
• Circulating myelinotoxic factors in human and experimental demyelinative disease.

  1983cited by this paper
• Neuroimmunology II: Antigenic specificity of the nervous system

  1982cited by this paper
• Kinetics of Neutral Amino Acid Transport Through the Blood‐Brain Barrier of the Newborn Rabbit

  1982cited by this paper
• Blood-Brain Barrier Permeability to Lactic Acid in the Newborn Dog: Lactate as a Cerebral Metabolic Fuel

  1982cited by this paper
• Comparison of lipid-mediated blood-brain-barrier penetrability in neonates and adults.

  1982cited by this paper
• Weakening of the blood-brain barrier by alcohol-related stresses in the rat.

  1982cited by this paper
• Developmental Modulations of Blood-Brain Barrier Permeability as an Indicator of Changing Nutritional Requirements in the Brain

  1982cited by this paper
• UCLA conference. Interferon: immunobiology and clinical significance.

  1982cited by this paper
• Pharmacokinetics of continuous intravenous and subcutaneous infusions of cytosine arabinoside.

  1982cited by this paper
• Absence of evoked potential abnormalities in acute transverse myelopathy

  1982cited by this paper
• Acidosis‐Induced Enhanced Activity of the Na‐K Exchange Pump in the In Vivo Choroid Plexus: An Ontogenetic Analysis of Possible Role in Cerebrospinal Fluid pH Homeostasis

  1982cited by this paper
• Immunopathologic Disease of the Central Nervous System

  1982cited by this paper
• Combined cyclotron fast-neutron and BCNU therapy in a rat brain-tumor model.

  1981cited by this paper
• Transplantation of central nervous tissue

  1981cited by this paper
• Does ethanol damage the blood--brain barrier?

  1981cited by this paper
• Development of brain capillaries in euthyroid and hypothyroid rats.

  1981cited by this paper
• Non-saturable transport of [3H]oestradiol across the blood-brain barrier in female rats is reduced by neonatal serum.

  1981cited by this paper
• Rapid evolution of central nervous system lymphoma in renal transplant recipient.

  1981cited by this paper
• Loss of suppressor T cells in active multiple sclerosis. Analysis with monoclonal antibodies.

  1980cited by this paper
• Chlorambucil inhibition by dimethyl sulfoxide and thiosulfate: implications for chlorambucil chemotherapy.

  1980cited by this paper
• A study of cephalothin and desacetylcephalothin in cerebrospinal fluid in therapy for experimental pneumococcal meningitis.

  1980cited by this paper
• Permeability and vascularity of the developing brain: cerebellum vs cerebral cortex.

  1980cited by this paper
• Immunobiologic aspects of the brain and human gliomas. A review.

  1980cited by this paper
• Interaction between phenytoin and valproic acid: Plasma protein binding and metabolic effects

  1980cited by this paper
• Autoregulation of cerebral blood flow in the newborn dog.

  1980cited by this paper
• Sparing of the brain in neonatal undernutrition: amino acid transport and incorporation into brain and muscle.

  1980cited by this paper
• Autoantibodies against axonal neurofilaments in patients with Kuru and Creutzfeldt-Jakob disease.

  1980cited by this paper
• Transport of Albumin‐bound Melatonin Through the Blood‐Brain Barrier

  1980cited by this paper
• Effect of various lead doses on some cerebral capillary functions in the suckling rat.

  1980cited by this paper
• Transport of thyroid and steroid hormones through the blood-brain barrier of the newborn rabbit: primary role of protein-bound hormone.

  1980cited by this paper
• Molecular biology and chemistry of the alternative pathway of complement.

  1980cited by this paper
• Protein mediated chemical reactions of chloroethylnitrosoureas.

  1980cited by this paper
• Prolactin in cerebrospinal fluid: a probable site of prolactin autoregulation.

  1980cited by this paper
• Clinical Aspects of Neuroimmunology

  1980cited by this paper
• Newborn Rabbit Blood–Brain Barrier Is Selectively Permeable and Differs Substantially from the Adult

  1980cited by this paper
• Impaired autoregulation of cerebral blood flow in the distressed newborn infant.

  1979cited by this paper
• Studies of the development of brain barrier systems to lipid insoluble molecules in fetal sheep.

  1979cited by this paper
• KINETICS OF BLOOD‐BRAIN BARRIER TRANSPORT OF PYRUVATE, LACTATE AND GLUCOSE IN SUCKLING, WEANLING AND ADULT RATS

  1979cited by this paper
• Distribution of fluid between extracellular and intracellular compartments in the heart, lungs, liver and spleen of neonatal rats.

  1979cited by this paper
• Experimental approaches to the treatment of CNS leukemia.

  1979cited by this paper
• Clinical Pharmacokinetics of Methotrexate

  1978cited by this paper
• Clinical studies of intrathecal autologous lymphocyte infusions in patients with malignant glioma: A toxicity study

  1978cited by this paper
• Baclofen: effects on amino acid release.

  1978cited by this paper
• Fast-neutron irradiation of glioblastoma multiforme. Neuropathological analysis.

  1978cited by this paper
• The effect of age upon the influx of glucose into the brain.

  1978cited by this paper
• CEREBRAL BLOOD FLOW AND CEREBRAL METABOLIC RATES FOR OXYGEN, GLUCOSE, AND KETONE BODIES IN NEWBORN DOGS

  1978cited by this paper
• Choroid epithelial cell pH.

  1978cited by this paper

• ANN multi-layer perceptron for prediction of blood–brain barrier permeable compounds for central nervous system therapeutics

  2024cites this paper
• The S1 protein of SARS-CoV-2 crosses the blood-brain barrier: Kinetics, distribution, mechanisms, and influence of ApoE genotype, sex, and inflammation

  2020cites this paper
• Seeing the Brain Through the Eye: What Is Next for Neuroimaging and Neurology Applications

  2020cites this paper
• Mannitol Enhances the Antinociceptive Effects of Diphenhydramine as an Alternative Local Anesthetic

  2020cites this paper
• Delivery of Antineoplastic Therapeutics to the Central Nervous System

  2019cites this paper
• Mécanismes de neuroprotection liés au glutathion dans la barrière sang - liquide céphalorachidien choroïdienne au cours du développement périnatal

  2019cites this paper
• Solid lipid nanoparticles as a drug delivery system to across the blood-brain barrier.

  2019cites this paper
• Convection-Enhanced Delivery in Malignant Gliomas: A Review of Toxicity and Efficacy

  2019cites this paper
• Improved Classification of Blood-Brain-Barrier Drugs Using Deep Learning

  2019cites this paper
• Potential role of arteether on N-methyl-D-aspartate (NMDA) receptor expression in experimental cerebral malaria mice and extension of their survival

  2019cites this paper
• Role of Blood Retinal Barrier in Drug Absorption

  2018cites this paper
• Barriers to Drug Distribution into the Perinatal and Postnatal Brain

  2018cites this paper
• Small endogenous molecules as moiety to improve targeting of CNS drugs

  2017influential citation
• Differential modulation of glial cell mediated neuroinflammation in Plasmodium berghei ANKA infection by TGF &bgr; and IL 6

  2017cites this paper
• Mutant smoothened et méthodes d'utilisation dudit mutant

  2017cites this paper
• Retinal microvascular network alterations: potential biomarkers of cerebrovascular and neural diseases.

  2017cites this paper
• Optimizing superparamagnetic iron oxide nanoparticles as drug carriers using an in vitro blood–brain barrier model

  2016cites this paper
• Inhibiteurs de dlk tricycliques et utilisations associées

  2016cites this paper
• Computational pharmacokinetic rationale for intra-arterial delivery to the brain

  2016cites this paper
• DEVELOPMENT OF THE BLOOD-BRAIN BARRIER IN THE ONTOGENESIS IN THE LIGHT OF IMMUNOHISTOCHEMICAL ANALYSIS OF NEUROSPECIFIC PROTEINS

  2016cites this paper
• Reassessing the Role of Intra-Arterial Drug Delivery for Glioblastoma Multiforme Treatment

  2015cites this paper
• Recent prospective of surface engineered Nanoparticles in the management of Neurodegenerative disorders

  2015cites this paper
• Anticorps contre bace1 et utilisation de ceux-ci pour l'immunothérapie contre les maladies neurales

  2015cites this paper
• Anticorps anti-tau humanisés dans la maladie d'alzheimer

  2015cites this paper
• Delivery of chemotherapeutics across the blood-brain barrier: challenges and advances.

  2014cites this paper
• Osmotic Opening of the BBB for Drug Treatment of Brain Tumors (Focus on Methodological Issues)

  2014cites this paper
• Highly Sensitive Visualization of Inorganic Mercury in Mouse Neurons Using a Fluorescent Probe

  2014cites this paper
• BRITISH BIOMEDICAL BULLETIN

  2014cites this paper
• Electron microscopic features of brain edema in rodent cerebral malaria in relation to glial fibrillary acidic protein expression.

  2014cites this paper
• Composés de sulfonamide substitués

  2013cites this paper
• Effects of blockade of NMDA receptors on cerebral oxygen consumption during hyperosmolar BBB disruption in rats.

  2013cites this paper
• Mechanism of polymeric nanoparticle-based drug transport across the blood-brain barrier (BBB)

  2013cites this paper
• Prediction of passive blood-brain barrier permeability with PAMPA: from small molecules to complex formulations

  2013cites this paper
• Benzamides n-substitués et leurs procédés d'utilisation

  2013cites this paper
• In Vivo Approaches to Assessing the Blood–Brain Barrier

  2013cites this paper
• Effects of the Thioredoxin-1 Inhibitor PX-12 on Blood-Brain Barrier Permeability in the Early Stage of Focal Cerebral Ischemia

  2013cites this paper
• Anticorps tau humanisé

  2013cites this paper
• Methodologies to Assess Drug Permeation Through the Blood–Brain Barrier for Pharmaceutical Research

  2013cites this paper
• A new method of quantitatively assessing the opening of the blood-brain barrier in murine animal models.

  2012cites this paper
• Kreislaufstörungen des ZNS

  2012cites this paper
• Pharmacokinetics and modeling of immune cell trafficking: quantifying differential influences of target tissues versus lymphocytes in SJL and lipopolysaccharide-treated mice

  2012cites this paper
• Central Nervous System: Viral Infection and Immune-Mediated Inflammation

  2012cites this paper
• Evaluation of the increase in permeability of the blood–brain barrier during tumor progression after pulsed focused ultrasound

  2012cites this paper
• Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model

  2012cites this paper
• A model for lupus brain disease

  2012cites this paper
• Kinetics of transport of doxorubicin bound to nanoparticles across the blood-brain barrier.

  2011cites this paper
• Préparation d'un produit de recombinaison antigénique

  2011cites this paper
• Vaccin obtenu par génie génétique

  2011cites this paper
• Blood-brain barrier disruption in the treatment of brain tumors.

  2011cites this paper
• Strategies to optimize the brain availability of central nervous system drug candidates

  2011cites this paper
• A novel free radical scavenger rescues retinal cells in vivo.

  2011cites this paper
• Brain Metastases from Breast Cancer: Treatment and Prognosis

  2011cites this paper
• Effect of Vitamin E on Blood-Brain Barrier Permeability in Aged Rats with PTZ-Induced Convulsions

  2011cites this paper
• Micro-SPECT/CT–Based Pharmacokinetic Analysis of 99mTc-Diethylenetriaminepentaacetic Acid in Rats with Blood–Brain Barrier Disruption Induced by Focused Ultrasound

  2011cites this paper
• The Use of Convection-Enhanced Delivery with Liposomal Toxins in Neurooncology

  2011cites this paper
• A Carrier for Non-Covalent Delivery of Functional Beta-Galactosidase and Antibodies against Amyloid Plaques and IgM to the Brain

  2011cites this paper
• Effects of GABA(A) receptor blockade on regional cerebral blood flow and blood-brain barrier disruption in focal cerebral ischemia.

  2011cites this paper
• Anticorps humanisés sûrs et fonctionnels

  2011cites this paper
• Transporters in the Blood-Brain Barrier

  2011cites this paper
• Nano-interventions for neurodegenerative disorders.

  2010cites this paper
• The blood-brain barrier and immune function and dysfunction.

  2010cites this paper
• The Effects of Isoflurane Pretreatment on Cerebral Blood Flow, Capillary Permeability, and Oxygen Consumption in Focal Cerebral Ischemia in Rats

  2010cites this paper
• Homeostatic regulation of the endoneurial microenvironment during development, aging and in response to trauma, disease and toxic insult

  2010cites this paper
• Mouse models of neurological disorders: a view from the blood-brain barrier.

  2010cites this paper
• Circulating brain-reactive autoantibodies and behavioral deficits in the MRL model of CNS lupus.

  2010cites this paper
• NEUROSURGICAL STRATEGY FOR DRUG DELIVERY TO BRAIN

  2010cites this paper
• Modulation de la dégénérescence axonale

  2010cites this paper
• Chemotherapy for Glioblastoma: Past, Present, and Future

  2010cites this paper
• Blood-brain interfaces and cerebral drug bioavailability.

  2009cites this paper
• Manganese Flux Across the Blood–Brain Barrier

  2009cites this paper
• The possible use of oximes as antidotal therapy in organophosphate-induced brain damage.

  2009cites this paper
• CNS drug delivery systems: novel approaches.

  2009cites this paper
• Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones.

  2009cites this paper
• Getting into the Brain

  2009cites this paper
• Peripheral and central biodistribution of (111)In-labeled anti-beta-amyloid autoantibodies in a transgenic mouse model of Alzheimer's disease.

  2009cites this paper
• Mechanisms of the Penetration of Blood-Borne Substances into the Brain

  2009cites this paper
• Vanishing glioblastoma after corticosteroid therapy.

  2009cites this paper
• Examining Committee

  2009cites this paper
• Brain herniation

  2008cites this paper
• Altered consciousness associated with brain neoplasms.

  2008cites this paper
• Biomedical Technologies for in vitro Screening and Controlled Delivery of Neuroactive Compounds.

  2008cites this paper
• Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation.

  2008cites this paper
• Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease.

  2008cites this paper
• Recent Advances in Blood–Brain Barrier Disruption as a CNS Delivery Strategy

  2008cites this paper
• Effects of VEGF on the Blood-Brain Barrier Disruption Caused by Hyperosmolarity

  2008cites this paper
• Osmotic- and Stroke-Induced Blood-Brain Barrier Disruption Detected by Manganese-Enhanced Magnetic Resonance Imaging

  2007influential citation
• rt-PA causes a dose-dependent increase in the extravasation of cellular and non-cellular blood elements after focal cerebral ischemia.

  2007cites this paper
• Differentiating embryonic neural progenitor cells induce blood–brain barrier properties

  2007cites this paper
• Treatment and prognosis of brain metastases from breast cancer

  2007cites this paper
• Procédés et compositions se rapportant aux polypeptides zpa

  2007cites this paper
• Cholestanol metabolism in patients with cerebrotendinous xanthomatosis: absorption, turnover, and tissue deposition Published, JLR Papers in Press, October 1, 2006.

  2007cites this paper
• Blood–Retina Barriers

  2007cites this paper
• Enhanced Disruption of the Blood Brain Barrier by Intracarotid Mannitol Injection During Transient Cerebral Hypoperfusion in Rabbits

  2007cites this paper
• Neuroimmunopathology in a murine model of neuropsychiatric lupus.

  2007cites this paper
• Transient cortical blindness after cardiac catheterization with iobitridol.

  2007cites this paper
• Prodrug Approaches for Drug Delivery to the Brain

  2007cites this paper
• Human lupus autoantibodies against NMDA receptors mediate cognitive impairment

  2006cites this paper
• Long-term L-NAME treatment potentiates the blood-brain barrier disruption during pentylenetetrazole-induced seizures in rats.

  2006cites this paper
• Ferroportin in the postnatal rat brain: implications for axonal transport and neuronal export of iron.

  2006cites this paper
• A PHARMACOKINETIC STUDY OF DIPHENHYDRAMINE TRANSPORT ACROSS THE BLOOD-BRAIN BARRIER IN ADULT SHEEP: POTENTIAL INVOLVEMENT OF A CARRIER-MEDIATED MECHANISM

  2006cites this paper