Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Archives of General Psychiatry

• Publication date

  2009-09-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1001/archgenpsychiatry.2009.114PMID 19736354PMCID PMC3750953
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Diagnostic Interview Schedule for DSM-IV (DIS-IV)

  2010cited by this paper
• Genetic Effects on Environmental Vulnerability to Disease

  2009cited by this paper
• Neural substrates of increased memory sensitivity for negative stimuli in major depression.

  2008cited by this paper
• Meta-analyses of genetic studies on major depressive disorder

  2008cited by this paper
• Elevated inflammation levels in depressed adults with a history of childhood maltreatment.

  2008cited by this paper
• An unnecessary battle

  2008cited by this paper
• Psychiatric genetics: progress amid controversy

  2008cited by this paper
• Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene.

  2008influential reference
• Interactions of child maltreatment and serotonin transporter and monoamine oxidase A polymorphisms: Depressive symptomatology among adolescents from low socioeconomic status backgrounds

  2007cited by this paper
• Depression, chronic diseases, and decrements in health: results from the World Health Surveys.

  2007cited by this paper
• Activation of basolateral amygdala corticotropin-releasing factor 1 receptors modulates the consolidation of contextual fear.

  2007cited by this paper
• [Depression and stress: is there an endophenotype?].

  2007cited by this paper
• The neurobiology of stress and development.

  2007cited by this paper
• Amygdala reactivity and mood-congruent memory in individuals at risk for depressive relapse.

  2007cited by this paper
• Gene–environment interactions in psychiatry: joining forces with neuroscience

  2006cited by this paper
• MAOA and the "cycle of violence:" childhood abuse and neglect, MAOA genotype, and risk for violent and antisocial behavior.

  2006cited by this paper
• Sticks, stones, and hurtful words: relative effects of various forms of childhood maltreatment.

  2006cited by this paper
• Strategy for investigating interactions between measured genes and measured environments.

  2005cited by this paper
• Importance of Studying the Contributions of Early Adverse Experience to Neurobiological Findings in Depression

  2004cited by this paper
• The amygdala modulates the consolidation of memories of emotionally arousing experiences.

  2004cited by this paper
• Social supports and serotonin transporter gene moderate depression in maltreated children.

  2004cited by this paper
• Comparison of prospective and retrospective methods for haplotype inference in case‐control studies

  2004cited by this paper
• Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene

  2003cited by this paper
• Estimation and Tests of Haplotype-Environment Interaction when Linkage Phase Is Ambiguous

  2003cited by this paper
• Will the genomics revolution revolutionize psychiatry?

  2003cited by this paper
• Involvement of stress-released corticotropin-releasing hormone in the basolateral amygdala in regulating memory consolidation

  2002cited by this paper
• Teen-aged mothers in contemporary Britain.

  2002cited by this paper
• Addictions: A Community Reinforcement Approach to Addiction Treatment. Edited by R. J. Meyers and W. R. Miller. (Pp. 188; £49.95/$74.95.) Cambridge University Press: Cambridge. 2001.

  2002cited by this paper
• Role of Genotype in the Cycle of Violence in Maltreated Children

  2002cited by this paper
• Memory--a century of consolidation.

  2000cited by this paper
• Genetic epidemiology of major depression: review and meta-analysis.

  2000cited by this paper
• Immunocytochemical distribution of corticotropin‐releasing hormone receptor type‐1 (CRF1)‐like immunoreactivity in the mouse brain: Light microscopy analysis using an antibody directed against the C‐terminus

  2000cited by this paper
• Corticotropin-releasing hormone receptor subtypes and emotion.

  1999influential reference
• Childhood Trauma Questionnaire: A retrospective self-report

  1998cited by this paper
• Clinical characteristics of women with a history of childhood abuse: unhealed wounds.

  1997cited by this paper
• Implicit and explicit memory for emotion-congruent information in clinical depression and anxiety.

  1995cited by this paper
• Childhood adversities and adult depression: basic patterns of association in a US national survey

  1993cited by this paper
• Mood-congruent memory in depression: emotional priming or elaboration?

  1992cited by this paper
• Physiology and pharmacology of corticotropin-releasing factor.

  1991cited by this paper

• The role of MED22 and its transcriptional interactions with childhood trauma and trauma-focused psychotherapy in patients with major depressive disorder.

  2025cites this paper
• The Influence of Genetic Polymorphisms and Psychosocial Determinants on Suicidal Behaviors: A Case–Control Study of CRHR1, NTRK2, and FKBP5

  2025cites this paper
• Glucocorticoid receptor gene (NR3C1) methylation, childhood maltreatment, multilevel reward responsiveness and depressive and anxiety symptoms: A neuroimaging epigenetic study

  2025cites this paper
• Polygenic Predisposition, Multifaceted Family Protection, and Mental Health Development from Middle to Late Adulthood: A National Life Course Gene–Environment Study

  2025cites this paper
• Integrative Genome-Wide Association Studies of COVID-19 Susceptibility and Hospitalization Reveal Risk Loci for Long COVID

  2025cites this paper
• Narrative Review: A Neurobiological Perspective on Resilience in Youth

  2024cites this paper
• Early life adversities, psychopathologies and novel pharmacological strategies.

  2024cites this paper
• [Emotional Abuse in Childhood and Adolescence: Biological Embedding and Clinical Implications].

  2024cites this paper
• The Individual and Societal Burden of Treatment-Resistant Depression: An Overview.

  2023cites this paper
• Sleep and violence perpetration: A review of biological and environmental substrates

  2022cites this paper
• Genetic Variants Associated With Resilience in Human and Animal Studies

  2022cites this paper
• Child Maltreatment and Global Health: Biocultural Perspectives

  2022cites this paper
• Relations among CRFR1 and FKBP5 genotype, cortisol, and cognitive function in aging humans: A Project FRONTIER study.

  2022cites this paper
• Exploration of the Moderating Effects of Physical Activity and Early Life Stress on the Relation between Brain-Derived Neurotrophic Factor (BDNF) rs6265 Variants and Depressive Symptoms among Adolescents

  2022cites this paper
• Involvement of Nuclear Factor-κB in Inflammation and Neuronal Plasticity Associated with Post-Traumatic Stress Disorder

  2022cites this paper
• Stress and Susceptibility: A Systematic Review of Prenatal Epigenetic Risks for Developing Post-Traumatic Stress Disorder

  2022cites this paper
• Etiology of Depression: Biological and Environmental Factors in the Development of Depression

  2021cites this paper
• Gestational Stress and Resilience: Perspectives to Guide Interdisciplinary Research

  2021cites this paper
• Posttraumatic Stress Disorder and Anxiety-Related Conditions

  2021cites this paper
• Transcriptional and Epigenetic Regulation of the Corticotropin-Releasing Hormone System and Genetic Associations With Neuropsychiatric Disorders

  2021cites this paper
• The association between abusive supervision and anxiety in female employees is stronger in carriers of the CRHR1 TAT haplotype

  2021cites this paper
• Child Maltreatment

  2021cites this paper
• Multiomic biological approaches to the study of child abuse and neglect.

  2021cites this paper
• Prenatal and postnatal exposure to Tangshan earthquake and CRHR1 gene polymorphism influence risk of sleep disturbance in adulthood

  2021cites this paper
• A comprehensive gene-centric pleiotropic association analysis for 14 psychiatric disorders with GWAS summary statistics

  2021cites this paper
• Corticotropin releasing hormone receptor CRHR1 gene is associated with tianeptine antidepressant response in a large sample of outpatients from real-life settings

  2020cites this paper
• Salivary cortisol response to psychosocial stress in the late evening depends on CRHR1 genotype.

  2020cites this paper
• Biological correlates of early life stressful events in major depressive disorder.

  2020cites this paper
• Interaction Between Genes and Childhood Trauma on the Outcome of Psychiatric Disorders

  2020cites this paper
• Maltreatment timing, HPA axis functioning, multigenic risk, and depressive symptoms in African American youth: Differential associations without moderated mediation

  2020cites this paper
• Interactions of childhood maltreatment and genetic variations in adult depression: A systematic review.

  2020cites this paper
• Measuring resilience in children: a review of recent literature and recommendations for future research

  2020cites this paper
• Corticotropin-Releasing Factor Family: A Stress Hormone-Receptor System’s Emerging Role in Mediating Sex-Specific Signaling

  2020cites this paper
• HPA-axis multilocus genetic profile score moderates the association between maternal prenatal perceived stress and offspring depression in early adulthood

  2020cites this paper
• Understanding resilience

  2020cites this paper
• Gene–environment interactions between HPA-axis genes and childhood maltreatment in depression: a systematic review

  2020influential citation
• Childhood Trauma in Mental Disorders: A Comprehensive Approach

  2020cites this paper
• Effect of corticotropin-releasing hormone receptor1 gene variation on psychosocial stress reaction via the dorsal anterior cingulate cortex in healthy adults.

  2019cites this paper
• Systems Approach to Identify Common Genes and Pathways Associated with Response to Selective Serotonin Reuptake Inhibitors and Major Depression Risk

  2019cites this paper
• FAAH genotype, CRFR1 genotype, and cortisol interact to predict anxiety in an aging, rural Hispanic population: A Project FRONTIER study

  2019cites this paper
• Stress, psychiatric disorders, molecular targets, and more.

  2019cites this paper
• Ethical considerations for conducting cross-cultural biological psychiatry and prevention research on depression among adolescents in low- and middle-income countries

  2019cites this paper
• Early traumatic experiences and their relationship with the emergence of depressive symptoms in adulthood

  2019cites this paper
• Gene-Environment Interactions and Epigenetic Mechanisms in Depression

  2019cites this paper
• Bringing Together Cognitive and Genetic Approaches to the Understanding of Stress Vulnerability and Psychological Well-Being

  2019cites this paper
• Genetics of Resilience: Gene-by-Environment Interaction Studies as a Tool to Dissect Mechanisms of Resilience.

  2019cites this paper
• DNA methylation of HPA-axis genes and the onset of major depressive disorder in adolescent girls: a prospective analysis

  2019cites this paper
• Depressive Disorders: Mechanisms, Measurement and Management

  2019cites this paper
• Advance in Stress for Depressive Disorder.

  2019cites this paper
• Genetics of resilience: Implications from genome‐wide association studies and candidate genes of the stress response system in posttraumatic stress disorder and depression

  2019cites this paper
• Psychobiological Consequences of Child Maltreatment

  2018cites this paper
• Physiological Resilience and the Impact on Health

  2018cites this paper
• Family environment interacts with CRHR1 rs17689918 to predict mental health and behavioral outcomes

  2018cites this paper
• HPA-axis multilocus genetic variation moderates associations between environmental stress and depressive symptoms among adolescents

  2018influential citation
• Childhood adversity as a transdiagnostic risk factor for affective disorders in adulthood: A systematic review focusing on biopsychosocial moderating and mediating variables.

  2018cites this paper
• Corticotropin-releasing factor 1 receptor haplotype and cognitive features of major depression

  2018cites this paper
• Childhood interpersonal violence and adult alcohol, cannabis, and tobacco use disorders: variation by race/ethnicity?

  2018cites this paper
• The Corticotropin-Releasing Factor Family: Physiology of the Stress Response.

  2018cites this paper
• Childhood trauma interacted with BDNF Val66Met influence schizophrenic symptoms

  2018cites this paper
• Biological alterations affecting risk of adult psychopathology following childhood trauma: A review of sex differences.

  2018cites this paper
• Maternal depression in the intergenerational transmission of childhood maltreatment and its sequelae: Testing postpartum effects in a longitudinal birth cohort

  2018cites this paper
• Psychopathological consequences of maltreatment among children and adolescents: A systematic review of the GxE literature.

  2018cites this paper
• Internalizing Psychopathology across the Life Course: From Genes and Environment to Gene-Environment Interaction

  2017cites this paper
• HPA Axis Multilocus Genetic Profile Score Moderates the Impact of Interpersonal Stress on Prospective Increases in Depressive Symptoms for Offspring of Depressed Mothers

  2017influential citation
• RORA Polymorphism Interacts with Childhood Maltreatment in Determining Anxiety Sensitivity by Sex: A Preliminary Study in Healthy Young Adults

  2017cites this paper
• Traumatic stress and accelerated DNA methylation age: A meta-analysis.

  2017cites this paper
• Trauma and traumatic stress in a sample of pregnant women.

  2017cites this paper
• Do children fare for better and for worse? Associations among child features and parenting with child competence and symptoms

  2017cites this paper
• Effects of adolescent alcohol exposure on stress-induced reward deficits, brain CRF, monoamines and glutamate in adult rats

  2017cites this paper
• Resilience in refugee and Dutch adolescents: Genetic variability in the corticotropin releasing hormone receptor 1 ☆

  2017cites this paper
• Treating Chronic Stress to Address the Growing Problem of Depression and Anxiety

  2017cites this paper
• Genetic Influence on Resilience to Potentially Traumatic Events

  2017influential citation
• The sex-dependent role of the glucocorticoid receptor in depression: variations in the NR3C1 gene are associated with major depressive disorder in women but not in men

  2017cites this paper
• The interaction of corticotropin‐releasing hormone receptor gene and early life stress on emotional empathy

  2017cites this paper
• Gene × Environment Interactions: From Molecular Mechanisms to Behavior

  2017cites this paper
• Molecular and Epigenetic Mechanisms for the Complex Effects of Stress on Synaptic Physiology and Cognitive Functions

  2017cites this paper
• Effects of crack cocaine addiction and stress-related genes on peripheral BDNF levels.

  2017cites this paper
• Polymorphism in CRHR1 gene affects the IL-1β levels in suicidal attempters.

  2017cites this paper
• Adapting to Stress: Understanding the Neurobiology of Resilience

  2017cites this paper
• Role of neuroinflammation and sex hormones in war-related PTSD.

  2016cites this paper
• RDoC and translational perspectives on the genetics of trauma‐related psychiatric disorders

  2016cites this paper
• The Links Between Stress and Depression: Psychoneuroendocrinological, Genetic, and Environmental Interactions.

  2016cites this paper
• The Factor Structure, Predictors, and Percentile Norms of the Center for Epidemiologic Studies Depression (CES-D) Scale in the Dutch-speaking Adult Population of Belgium

  2016cites this paper
• Comportamento social e volume de substância branca cerebral em adolescentes vítimas de maus tratos

  2016cites this paper
• The CRF System as a Therapeutic Target for Neuropsychiatric Disorders.

  2016influential citation
• Childhood trauma and treatment outcome in bipolar disorder

  2016cites this paper
• Allelic variation in CRHR1 predisposes to panic disorder: evidence for biased fear processing

  2016cites this paper
• Neurobehavioral foundation of environmental reactivity.

  2016cites this paper
• Alterations in the corticotropin-releasing hormone (CRH) neurocircuitry: Insights into post stroke functional impairments.

  2016cites this paper
• Cardiac CRFR1 Expression Is Elevated in Human Heart Failure and Modulated by Genetic Variation and Alternative Splicing.

  2016cites this paper
• Neural correlates of gene-environment interactions in ADHD

  2016cites this paper
• Attentional biases to emotional stimuli: Key components of the RDoC constructs of sustained threat and loss

  2016cites this paper
• Associations between Single-Nucleotide Polymorphisms in Corticotropin-Releasing Hormone-Related Genes and Irritable Bowel Syndrome

  2016cites this paper
• Dopamine Rebound-Excitation Theory: Putting Brakes on PTSD

  2016cites this paper
• Genetic Process in Resilience and Vulnerability and the Consequence of Abuse

  2016cites this paper
• Influence of maternal depression on children's brooding rumination: Moderation by CRHR1 TAT haplotype

  2016influential citation
• Borderline Personality Disorder 'fast and furious'?

  2016cites this paper
• Integrating Cognitive Processing, Brain Activity, Molecules and Genes to Advance Evidence-Based Psychological Treatment for Depression and Anxiety: From Cognitive Neurogenetics to CBT-Based Neurogenetics

  2016cites this paper
• Corticotropin-Releasing Hormone Receptor 2 Gene Variants in Irritable Bowel Syndrome

  2016cites this paper
• A role for CRH and HPA Activation in the Regulation of Plasticity Signaling, Neuroinflammation and Emotional/Mnesic Behavior Following Global Cerebral Ischemia in Rats

  2016cites this paper