Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2004-11-05

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.BBRC.2004.09.047PMID 15465013
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Clinical applications of PET in oncology.

  2004influential reference
• Measurement of cerebral glucose metabolic rates in the anesthetized rat by dynamic scanning with 18F-FDG, the ATLAS small animal PET scanner, and arterial blood sampling.

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