Differential blood flow responses to CO2 in human internal and external carotid and vertebral arteries

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Physiology

• Publication date

  2012-07-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1113/jphysiol.2012.230425PMID 22526884PMCID PMC3459042
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The distribution of blood flow in the carotid and vertebral arteries during dynamic exercise in humans

  2011cited by this paper
• Regulation of cerebral blood flow in mammals during chronic hypoxia: a matter of balance

  2010cited by this paper
• Influence of Changes in Blood Pressure on Cerebral Perfusion and Oxygenation

  2010cited by this paper
• Different blood flow responses to dynamic exercise between internal carotid and vertebral arteries in women.

  2010cited by this paper
• Integration of cerebrovascular CO2 reactivity and chemoreflex control of breathing: mechanisms of regulation, measurement, and interpretation.

  2009influential reference
• Cerebral blood flow during exercise: mechanisms of regulation.

  2009cited by this paper
• Human cerebral arteriovenous vasoactive exchange during alterations in arterial blood gases.

  2008cited by this paper
• Human cardiorespiratory and cerebrovascular function during severe passive hyperthermia: effects of mild hypohydration.

  2008cited by this paper
• Cerebellar Autoregulation Dynamics in Humans

  2008influential reference
• Interaction between the ventilatory and cerebrovascular responses to hypo‐ and hypercapnia at rest and during exercise

  2008cited by this paper
• Morning attenuation in cerebrovascular CO2 reactivity in healthy humans is associated with a lowered cerebral oxygenation and an augmented ventilatory response to CO2.

  2007influential reference
• Early morning impairment in cerebral autoregulation and cerebrovascular CO2 reactivity in healthy humans: relation to endothelial function

  2007influential reference
• Human cerebrovascular and ventilatory CO2 reactivity to end‐tidal, arterial and internal jugular vein PCO2

  2007influential reference
• Enhanced cerebral CO2 reactivity during strenuous exercise in man

  2006cited by this paper
• Differential responses to CO2 and sympathetic stimulation in the cerebral and femoral circulations in humans

  2005cited by this paper
• The effect of changes in cardiac output on middle cerebral artery mean blood velocity at rest and during exercise

  2005cited by this paper
• Regional cerebral autoregulation during orthostatic stress: age-related differences.

  2005cited by this paper
• Dynamic Autoregulation Testing in the Posterior Cerebral Artery

  2004cited by this paper
• Autoregulatory Response and CO2 Reactivity of the Basilar Artery

  2003influential reference
• Relationship between middle cerebral artery blood velocity and end-tidal PCO2 in the hypocapnic-hypercapnic range in humans.

  2003influential reference
• Cerebral Changes During Exercise in the Heat

  2003cited by this paper
• Inadequate heat release from the human brain during prolonged exercise with hyperthermia

  2002cited by this paper
• Regional differences in mechanisms of cerebral circulatory response to neuronal activation.

  2001cited by this paper
• Middle Cerebral Artery Flow Velocity Correlates With Common Carotid Artery Volume Flow Rate After CO2 Inhalation

  2001cited by this paper
• Regional Differences in Cerebral Vascular Response to Paco2 Changes in Humans Measured by Positron Emission Tomography

  2000cited by this paper
• MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis.

  2000cited by this paper
• Analysis of CO2 vasomotor reactivity and vessel diameter changes by simultaneous venous and arterial Doppler recordings.

  1999cited by this paper
• Influence of acetazolamide and CO2 on extracranial flow volume and intracranial blood flow velocity.

  1999influential reference
• Cerebral vasodilators.

  1998cited by this paper
• Sex dependency of cerebrovascular CO2 reactivity in normal subjects.

  1997cited by this paper
• CO2 response for the brain stem artery blood flow velocity in man.

  1996influential reference
• The Variability of Cerebrovascular Reactivity with Posture and Time

  1996cited by this paper
• Nitric oxide-dependent and -independent components of cerebrovasodilation elicited by hypercapnia.

  1994cited by this paper
• Estimation of Cerebral Blood Flow Through Color Duplex Sonography of the Carotid and Vertebral Arteries in Healthy Adults

  1994cited by this paper
• Nitric Oxide and the Cerebral Circulation

  1994cited by this paper
• Cerebral arterial diameters during changes in blood pressure and carbon dioxide during craniotomy.

  1993cited by this paper
• Cerebral autoregulation dynamics in humans.

  1989cited by this paper
• Heterogeneous vasomotor responses of anatomically distinct feline cerebral arteries

  1988cited by this paper
• Carbondioxide reactivity of the blood flow in human basilar artery estimated by the transcranial Doppler method in normal men: a comparison with that of the middle cerebral artery.

  1988influential reference
• Comparative Studies of Regional CNS Blood Flow Autoregulation and Responses to CO2 in the Cat: Effects of Altering Arterial Blood Pressure and PaCO2 on rCBF of Cerebrum, Cerebellum, and Spinal Cord

  1984cited by this paper
• Autonomic nerves, mast cells, and amine receptors in human brain vessels. A histochemical and pharmacological study.

  1976cited by this paper
• Cerebrovascular CO2 Reactivity in Normotensive and Hypertensive Man

  1976cited by this paper
• The Relationship of Regional Cerebrovascular CO2 Reactivity to Blood Pressure and Regional Resting Flow

  1973cited by this paper
• Effect of some respiratory maneuvers on cerebral and peripheral circulation, with special reference to maximum breathing, voluntary hyperventilation and the Valsalva maneuver.

  1973cited by this paper
• Cerebral vasodilators.

  1971cited by this paper
• The cerebral vascular response to reduction in arterial carbon dioxide tension.

  1962cited by this paper
• Cerebral blood flow and oxygen consumption in man.

  1959cited by this paper
• THE EFFECTS OF ALTERED ARTERIAL TENSIONS OF CARBON DIOXIDE AND OXYGEN ON CEREBRAL BLOOD FLOW AND CEREBRAL OXYGEN CONSUMPTION OF NORMAL YOUNG MEN.

  1948cited by this paper
• THE BLOOD FLOW IN THE BRAIN AND THE LEG OF MAN, AND THE CHANGES INDUCED BY ALTERATION OF BLOOD GASES.

  1932cited by this paper
• Journal of Cerebral Blood Flow and Metabolism Role of Potassium Channels in Regulation of Cerebral Vascular Tone

  year unknowncited by this paper

• A comparison of normobaric and hypobaric hypoxia effects on cerebrovascular response pre and post maximal exercise.

  2026cites this paper
• Regional changes in cerebral blood flow between the upright and supine posture and over 3 days of bed rest.

  2025cites this paper
• Correlation between hemodynamic characterizations of cervical arteries and changes in cerebral microcirculation under dobutamine stress: a self-controlled study

  2025cites this paper
• Cerebral Blood Flow in Orthostatic Intolerance

  2025cites this paper
• Regional dynamic cerebral autoregulation in acute poikilocapnic hypoxia.

  2025cites this paper
• Hot water immersion increases internal carotid artery shear rate but does not alter intracranial vascular reactivity to carbon dioxide.

  2025cites this paper
• Problems and solutions in quantifying cerebrovascular reactivity using BOLD-MRI

  2025influential citation
• Effect of short-term high-altitude acclimatization on the relationship between cerebral blood flow and symptoms of mild acute mountain sickness in males.

  2025cites this paper
• Ventilatory response to head‐down‐tilt in healthy human subjects

  2024cites this paper
• Comparable dynamic cerebral autoregulation and neurovascular coupling of the posterior cerebral artery between healthy men and women

  2024cites this paper
• Cerebrospinal fluid pressure dynamics across the intra- and postoperative setting: Retrospective study of a spine surgery cohort.

  2024cites this paper
• The complexity of cerebral blood flow regulation: the interaction of posture and vasomotor reactivity.

  2024cites this paper
• Regional cerebral perfusion and sympathetic activation during exercise in hypoxia and hypercapnia: preliminary insight into ‘Cushing's mechanism’

  2024cites this paper
• Exposure to passive heat and cold stress differentially modulates cerebrovascular-CO2 responsiveness

  2023cites this paper
• Lifelong exposure to high‐altitude hypoxia in humans is associated with improved redox homeostasis and structural–functional adaptations of the neurovascular unit

  2023cites this paper
• Influence of end‐tidal CO2 on cerebral blood flow during orthostatic stress in controls and adults with myalgic encephalomyelitis/chronic fatigue syndrome

  2023cites this paper
• Internal Carotid Artery Blood Flow Response to Anaesthesia, Pneumoperitoneum and Head-Up Tilt During Laparoscopic Cholecystectomy: A Clinical Study

  2023cites this paper
• Can Alterations in Cerebrovascular CO2 Reactivity Be Identified Using Transfer Function Analysis without the Requirement for Carbon Dioxide Inhalation?

  2023cites this paper
• Association of Intensive vs Standard Blood Pressure Control With Regional Changes in Cerebral Small Vessel Disease Biomarkers

  2023cites this paper
• Characterising spinal cerebrospinal fluid flow in the pig with phase-contrast magnetic resonance imaging

  2023cites this paper
• Menstrual phase influences cerebrovascular responsiveness in females but may not affect sex differences

  2023cites this paper
• Comparison of computational fluid dynamics with transcranial Doppler ultrasound in response to physiological stimuli

  2023cites this paper
• Acute Gravitational Stress Selectively Impairs Dynamic Cerebrovascular Reactivity in the Anterior Circulation Independent of Changes to the Central Respiratory Chemoreflex

  2022cites this paper
• Validity of transcranial Doppler ultrasonography-determined dynamic cerebral autoregulation estimated using transfer function analysis

  2022cites this paper
• Site-specific different dynamic cerebral autoregulation and cerebrovascular response to carbon dioxide in posterior cerebral circulation during isometric exercise in healthy young men.

  2022cites this paper
• How does head position induced intracranial pressure changes impact sympathetic activity and cerebral blood flow?

  2022cites this paper
• The relationships between age, sex, and cerebrovascular reactivity to hypercapnia using traditional and kinetic-based analyses in healthy adults

  2022cites this paper
• Caveolar disruption with methyl-β-cyclodextrin causes endothelium-dependent contractions in Wistar rat carotid arteries

  2022cites this paper
• Hypocapnia attenuates local skin thermal perception to innocuous warm and cool stimuli in normothermic resting humans.

  2022cites this paper
• Increased Carbon Dioxide Respiration Prevents the Effects of Acceleration/Deceleration Elicited Mild Traumatic Brain Injury.

  2022cites this paper
• Near Infrared Spectroscopy For Cerebral Hemodynamic Monitoring During Carotid Endarterectomy Under General Anesthesia

  2022cites this paper
• Hypercapnia elicits differential vascular and blood flow responses in the cerebral circulation and active skeletal muscles in exercising humans

  2022cites this paper
• Noninvasive Monitoring of Intracranial Pulse Waves

  2022cites this paper
• Effects of electrical muscle stimulation on cerebral blood flow

  2021cites this paper
• Cerebral blood flow remains reduced after tilt testing in myalgic encephalomyelitis/chronic fatigue syndrome patients

  2021cites this paper
• Intraoperative Monitoring of CSF Pressure in Patients with Degenerative Cervical Myelopathy (COMP-CORD Study): A Prospective Cohort Study

  2021cites this paper
• Regional Differences in Cerebrovascular Reactivity in Response to Acute Isocapnic Hypoxia in Healthy Humans: Methodological Considerations.

  2021cites this paper
• Integrated respiratory chemoreflex‐mediated regulation of cerebral blood flow in hypoxia: Implications for oxygen delivery and acute mountain sickness

  2021cites this paper
• A novel method of quantifying hemodynamic delays to improve hemodynamic response, and CVR estimates in CO2 challenge fMRI

  2021cites this paper
• The Acute Cardiorespiratory and Cerebrovascular Response to Resistance Exercise

  2021influential citation
• Arterial Spin Labeling Imaging Assessment of Cerebrovascular Reactivity in Hypertensive Small Vessel Disease

  2021cites this paper
• Dynamic cerebral autoregulation and cerebrovascular carbon dioxide reactivity in middle and posterior cerebral arteries in young endurance-trained women.

  2021cites this paper
• Reactive oxygen species play a modulatory role in the hyperventilatory response to poikilocapnic hyperoxia in humans

  2021influential citation
• Cerebral blood flow, cerebrovascular reactivity and their influence on ventilatory sensitivity

  2021cites this paper
• University of Birmingham Contrasting measures of cerebrovascular reactivity between MRI and Doppler

  2021cites this paper
• Cerebral blood flow impairment and cognitive decline in heart failure

  2021cites this paper
• Contrasting Measures of Cerebrovascular Reactivity Between MRI and Doppler: A Cross-Sectional Study of Younger and Older Healthy Individuals

  2021cites this paper
• Cerebrovascular carbon dioxide reactivity and flow mediated dilation in 1 young healthy South Asian and Caucasian European men 2

  2021cites this paper
• Bilateral regional extracranial blood flow regulation to hypoxia and unilateral duplex ultrasound measurement error

  2021cites this paper
• Effect of breath-hold on the responses of arterial blood pressure and cerebral blood velocity to isometric exercise

  2021cites this paper
• Parasympathetic brainstem origin sites of triggered external and internal carotid vasodilation are not distributed topographically in the rat.

  2021cites this paper
• Hemodynamic Modeling of the Circle of Willis Reveals Unanticipated Functions during Cardiovascular Stress.

  2021cites this paper
• Effect of 3% CO2 inhalation on respiratory exchange ratio and cardiac output during constant work-rate exercise.

  2020cites this paper
• Characterizing near‐infrared spectroscopy signal under hypercapnia

  2020cites this paper
• Gravitational transitions increase posterior cerebral perfusion and systemic oxidative-nitrosative stress: implications for neurovascular unit integrity.

  2020cites this paper
• Gravitational effects on intracranial pressures and blood flow regulation in young men: a potential shunting role for the external carotid artery.

  2020cites this paper
• Hypercapnia augments resistive exercise‐induced elevations in intraocular pressure in older individuals

  2020cites this paper
• Cerebrovascular carbon dioxide reactivity and flow mediated dilation in young healthy South Asian and Caucasian European men.

  2020cites this paper
• Specific effect of hypobaria on cerebrovascular hypercapnic responses in hypoxia

  2020cites this paper
• The effect of hypercapnia on regional cerebral blood flow regulation during progressive lower-body negative pressure

  2020cites this paper
• Dynamic cerebral autoregulation in anterior and posterior cerebral circulation during cold pressor test

  2020cites this paper
• The effect of hypercapnia on regional cerebral blood flow regulation during progressive lower-body negative pressure

  2020cites this paper
• Haemodynamic effects of hyperventilation on healthy men with different levels of autonomic tone

  2020cites this paper
• Respiratory alkalinization and posterior cerebral artery dilatation predict acute mountain sickness severity during 10 h normobaric hypoxia

  2020cites this paper
• Long‐duration spaceflight alters estimated intracranial pressure and cerebral blood velocity

  2020cites this paper
• Origin of the Time Lag Phenomenon and the Global Signal in Resting-State fMRI

  2020cites this paper
• Characterization of regional differences in cerebral vascular response to breath holding using BOLD fMRI

  2020cites this paper
• Acute effect of increased arterial stiffness with high-intensity resistance exercise on cerebral blood flow

  2019cites this paper
• The age‐related reduction in cerebral blood flow affects vertebral artery more than internal carotid artery blood flow

  2019influential citation
• Differential contribution of cyclooxygenase to basal cerebral blood flow and hypoxic cerebral vasodilation.

  2019cites this paper
• Sex differences in the circulatory responses to an isocapnic cold pressor test

  2019cites this paper
• The effect of muscle metaboreflex on the distribution of blood flow in cerebral arteries during isometric exercise

  2019cites this paper
• Arterial and venous cerebral blood flow responses to long‐term head‐down bed rest in male volunteers

  2019cites this paper
• Dietary nitrate supplementation enhances cerebrovascular CO2 reactivity in a sex-specific manner.

  2019cites this paper
• Effects of Resistance Exercise and Nutritional Supplementation on Dynamic Cerebral Autoregulation in Head-Down Bed Rest

  2019cites this paper
• Retractorless Surgery for Giant Vestibular Schwannomas via the Retrosigmoid Approach.

  2019cites this paper
• Regulation of the Cerebral Circulation by Arterial Carbon Dioxide.

  2019cites this paper
• Dynamic cerebral autoregulation is preserved during isometric handgrip and head‐down tilt in healthy volunteers

  2018influential citation
• Reduced arterial vasodilatation in response to hypoxia impairs cerebral and peripheral oxygen delivery in hypertensive men

  2018cites this paper
• Topographical distribution of perioperative cerebral infarction associated with transcatheter aortic valve implantation

  2018cites this paper
• Similarity between carotid and coronary artery responses to sympathetic stimulation and the role of α1-receptors in humans.

  2018cites this paper
• 1 RESPIRATION-RELATED CEREBRAL BLOOD FLOW VARIABILITY 1 INCREASES DURING CONTROL-MODE NON-INVASIVE VENTILATION IN 2 NORMOVOLEMIA AND HYPOVOLEMIA 3

  2018influential citation
• Acute reduction in posterior cerebral blood flow following isometric handgrip exercise is augmented by lower body negative pressure

  2018influential citation
• Cerebral arterial time constant calculated from the middle and posterior cerebral arteries in healthy subjects

  2018cites this paper
• Increase in carbon dioxide accelerates the performance of endurance exercise in rats

  2018cites this paper
• Cerebrovascular Reactivity during Prolonged Breath-Hold in Experienced Freedivers

  2018cites this paper
• Regulation of Regional Cerebral Blood Flow During Graded Reflex-Mediated Sympathetic Activation via Lower Body Negative Pressure.

  2018cites this paper
• Cerebral blood flow alteration following acute myocardial infarction in mice

  2018cites this paper
• Sodium nitroprusside dilates cerebral vessels and enhances internal carotid artery flow in young men

  2018cites this paper
• Human brain blood flow and metabolism during isocapnic hyperoxia: the role of reactive oxygen species

  2018influential citation
• Effect of healthy aging on cerebral blood flow, CO2 reactivity, and neurovascular coupling during exercise.

  2018cites this paper
• Cardiovascular adjustments during anticipated postural changes

  2018cites this paper
• Aging decreases CO2 reactivity in the retinal artery, but not in the ocular choroidal vessels; a cross-sectional study

  2018cites this paper
• Acute anti-psychotic modulation of the structure and function of the brain

  2018cites this paper
• Fluid intake restores retinal blood flow early after exhaustive exercise in healthy subjects

  2018cites this paper
• Similarity between carotid and coronary artery responses to sympathetic stimulation and the role of (cid:2) 1 -receptors in humans

  2018cites this paper
• On the regulation of oxygen delivery to the brain in humans

  2018cites this paper
• Aalborg Universitet Cardiovascular control during whole body exercise

  2017cites this paper
• Regulation of cerebral blood flow and metabolism during exercise

  2017cites this paper
• Relationship between cerebral arterial inflow and venous outflow during dynamic supine exercise

  2017cites this paper