Beyond early development: Xenopus as an emerging model for the study of regenerative mechanisms

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Developmental Dynamics

• Publication date

  2009-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/dvdy.21890PMID 19280606
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Xenopus Wnt-5a induces an ectopic larval tail at injured site, suggesting a crucial role for noncanonical Wnt signal in tail regeneration.

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  2009cited by this paper
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• Faulty old ideas about translational regulation paved the way for current confusion about how microRNAs function.

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• Spinal cord is required for proper regeneration of the tail in Xenopus tadpoles

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• Requirement for Wnt and FGF signaling in Xenopus tadpole tail regeneration.

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• Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish.

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• Identification of genes associated with regenerative success of Xenopus laevis hindlimbs

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  2007influential reference
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• MicroRNAs and regeneration: Let-7 members as potential regulators of dedifferentiation in lens and inner ear hair cell regeneration of the adult newt.

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• H+ pump-dependent changes in membrane voltage are an early mechanism necessary and sufficient to induce Xenopus tail regeneration

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• Wnt/beta-catenin signaling has an essential role in the initiation of limb regeneration.

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• Apoptosis is required during early stages of tail regeneration in Xenopus laevis.

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• MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3.

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• Light-controlled gene silencing in zebrafish embryos.

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• The diverse functions of microRNAs in animal development and disease.

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• Limb Regeneration in Xenopus laevis Froglet

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• Analysis of scleraxis and dermo‐1 genes in a regenerating limb of Xenopus laevis

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• Wnt/β-catenin signaling regulates vertebrate limb regeneration

  2006influential reference
• Genetic Screens for Mutations Affecting Development of Xenopus tropicalis

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• Temporal requirement for bone morphogenetic proteins in regeneration of the tail and limb of Xenopus tadpoles.

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• Wnt/beta-catenin signaling regulates vertebrate limb regeneration.

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• A bivalent chromatin structure marks key developmental genes in embryonic stem cells.

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• Experimental analysis of lens-forming capacity in Xenopus borealis larvae.

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• Global analysis of gene expression in Xenopus hindlimbs during stage‐dependent complete and incomplete regeneration

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• Cell-type-specific signatures of microRNAs on target mRNA expression.

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• Distinct Wnt signaling pathways have opposing roles in appendage regeneration

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• The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

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• How to build and rebuild a lens

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• Reversibility of the differentiated state: regeneration in amphibians.

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• Identification of microRNAs and other small RNAs from the adult newt eye.

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• Highly efficient transgenesis in Xenopus tropicalis using I-SceI meganuclease.

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• I‐SceI meganuclease‐mediated transgenesis in Xenopus

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• Newt Opportunities for Understanding the Dedifferentiation Process

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• Control of muscle regeneration in the Xenopus tadpole tail by Pax7

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• Multiple noggins in vertebrate genome: cloning and expression of noggin2 and noggin4 in Xenopus laevis.

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• Controlling cell behavior electrically: current views and future potential.

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• Hedgehog signaling controls dorsoventral patterning, blastema cell proliferation and cartilage induction during axolotl tail regeneration

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• Stage‐specific expression of microRNAs during Xenopus development

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• Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration

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• Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor

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• Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling.

  2005cited by this paper
• Lens-forming competence in the epidermis of Xenopus laevis during development.

  2005cited by this paper
• Strategies to reduce variation in Xenopus regeneration studies

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• fgf20 Is Essential for Initiating Zebrafish Fin Regeneration

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• Muscle formation in regenerating Xenopus froglet limb

  2005influential reference
• Macroarray‐based analysis of tail regeneration in Xenopus laevis larvae

  2005cited by this paper
• Characteristics of initiation and early events for muscle development in the Xenopus limb bud

  2005influential reference
• Therapeutic potential of transdifferentiated cells.

  2005cited by this paper
• Joint development in Xenopus laevis and induction of segmentations in regenerating froglet limb (spike)

  2005influential reference
• Nerve-dependent and -independent events in blastema formation during Xenopus froglet limb regeneration.

  2005cited by this paper
• Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb

  2005cited by this paper
• A critical role for thrombin in vertebrate lens regeneration.

  2004cited by this paper
• Cellular and molecular mechanisms of regeneration in Xenopus.

  2004influential reference
• Forelimb spike regeneration in Xenopus laevis: Testing for adaptiveness.

  2004influential reference
• Cell lineage tracing during Xenopus tail regeneration

  2004cited by this paper
• A stepwise model system for limb regeneration.

  2004cited by this paper
• Differential gene expression between the embryonic tail bud and regenerating larval tail in Xenopus laevis

  2004influential reference
• The Regenerative Plasticity of Isolated Urodele Myofibers and Its Dependence on Msx1

  2004cited by this paper
• Early regeneration genes: Building a molecular profile for shared expression in cornea–lens transdifferentiation and hindlimb regeneration in Xenopus laevis

  2004influential reference
• Regeneration‐specific expression pattern of three posterior Hox genes

  2003influential reference
• Tales of regeneration in zebrafish

  2003cited by this paper
• Tissue interactions and lens-forming competence in the outer cornea of larval Xenopus laevis.

  2003cited by this paper
• Molecular cloning of Xenupus HGF cDNA and its expression studies in Xenopus early embryogenesis

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• Tagging muscle cell lineages in development and tail regeneration using Cre recombinase in transgenic Xenopus.

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• Identification of genes expressed during Xenopus laevis limb regeneration by using subtractive hybridization

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• Molecular pathways needed for regeneration of spinal cord and muscle in a vertebrate.

  2003influential reference
• In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb.

  2002cited by this paper
• Cyclopamine induces digit loss in regenerating axolotl limbs.

  2002cited by this paper
• Characterizing gene expression during lens formation in Xenopus laevis: Evaluating the model for embryonic lens induction

  2002cited by this paper
• Limb muscle development.

  2002cited by this paper
• Plasticity and reprogramming of differentiated cells in amphibian regeneration

  2002cited by this paper
• Mps1 defines a proximal blastemal proliferative compartment essential for zebrafish fin regeneration.

  2002cited by this paper
• Ectoderm to Mesoderm Lineage Switching During Axolotl Tail Regeneration

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• Notch is required for outgrowth of the Xenopus tail bud.

  2002cited by this paper
• In vivo imaging indicates muscle fiber dedifferentiation is a major contributor to the regenerating tail blastema.

  2001cited by this paper
• FGF-10 stimulates limb regeneration ability in Xenopus laevis.

  2001cited by this paper
• Nerve-independence of limb regeneration in larval Xenopus laevis is correlated to the level of fgf-2 mRNA expression in limb tissues.

  2001cited by this paper
• An epidermal signal regulates Lmx-1 expression and dorsal-ventral pattern during Xenopus limb regeneration.

  2001cited by this paper
• The role of BMP signaling in outgrowth and patterning of the Xenopus tail bud.

  2001cited by this paper
• Cornea-lens transdifferentiation in the anuran, Xenopus tropicalis

  2001cited by this paper
• A simplified method of generating transgenic Xenopus.

  2000cited by this paper

• The Regenerative Stage‐Defined Neurogenic Properties in the Spinal Cord of Xenopus laevis: Correlation Between Neurogenic Potential and Functional Repair of the Spinal Cord

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• Programmed cell revival from imminent cell death enhances tissue repair and regeneration

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• Ageing versus developmental silencing: Answers from the epigenome

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• Commensal skin bacteria interact with the innate immune system to promote tail regeneration in Xenopus laevis tadpoles

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• Putative muscle stem cells promote Xenopus tail regeneration by modifying macrophage function via c1qtnf3.

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• Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

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• Injury-induced cooperation of InhibinβA and JunB is essential for cell proliferation in Xenopus tadpole tail regeneration

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• Notch Is Required for Neural Progenitor Proliferation During Embryonic Eye Regrowth

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• Tail Tales: What We Have Learned About Regeneration from Xenopus Laevis Tadpoles

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• Characterization of regeneration initiating cells during Xenopus laevis tail regeneration

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• Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

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• Adipose tissue derived stem cell secretome induces motor and histological gains after complete spinal cord injury in Xenopus laevis and mice

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• Deep transcriptome profiling reveals limited conservation of A-to-I RNA editing in Xenopus

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• Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax

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• regeneration factors expressed on myeloid expression in macrophage-like cells is required for tail regeneration in Xenopus laevis tadpoles

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• Characterization of regeneration initiating cells during Xenopus laevis tail regeneration

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• Xenopus laevis il11ra.L is an experimentally proven interleukin-11 receptor component that is required for tadpole tail regeneration

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• Tissue Rotation of the Xenopus Anterior–Posterior Neural Axis Reveals Profound but Transient Plasticity at the Mid-Gastrula Stage

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• Cellular responses in the FGF10‐mediated improvement of hindlimb regenerative capacity in Xenopus laevis revealed by single‐cell transcriptomics

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• Crustacean leg regeneration restores complex microanatomy and cell diversity

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• Effective enrichment of stem cells in regenerating Xenopus laevis tadpole tails using the side population method

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• Downregulation of Yap1 During Limb Regeneration Results in Defective Bone Formation in Axolotl

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• Chromatin accessibility analysis reveals distinct functions for HDAC and EZH2 activities in early appendage regeneration

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• Elevated pentose phosphate pathway flux supports appendage regeneration

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• To regenerate or not to regenerate: Vertebrate model organisms of regeneration‐competency and ‐incompetency

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• Inducing Vertebrate Limb Regeneration: A Review of Past Advances and Future Outlook.

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• Transcriptome profiling reveals gene regulation programs underlying tail development in the Ornamented Pygmy frog Microhyla fissipes.

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• Manipulating the microbiome alters regenerative outcomes in Xenopus laevis tadpoles via lipopolysaccharide signalling

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