BMP4 (bone morphogenetic protein 4)

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Atlas of genetics and cytogenetics in oncology and haematology

• Publication date

  2013-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4267/2042/50186
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Bone morphogenetic protein 4 expression in multiple normal and tumor tissues reveals its importance beyond development

  2013cited by this paper
• Upregulation of Bone Morphogenetic Protein 4 is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma

  2012cited by this paper
• The Activation of MEK/ERK Signaling Pathway by Bone Morphogenetic Protein 4 to Increase Hepatocellular Carcinoma Cell Proliferation and Migration

  2012influential reference
• Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus

  2012cited by this paper
• Genetic variation in bone morphogenetic protein and colon and rectal cancer

  2012cited by this paper
• Oncogenic KRAS regulates BMP4 expression in colon cancer cell lines.

  2012cited by this paper
• Bone morphogenetic protein 4-a fascinating regulator of cancer cell behavior.

  2012cited by this paper
• Integrated epigenomics identifies BMP4 as a modulator of cisplatin sensitivity in gastric cancer

  2012cited by this paper
• The 14q22.2 colorectal cancer variant rs4444235 shows cis-acting regulation of BMP4

  2012cited by this paper
• Establishment of a biomarker model for predicting bone metastasis in resected stage III non-small cell lung cancer

  2012cited by this paper
• Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC

  2012cited by this paper
• An Evolutionarily Conserved Enhancer Regulates Bmp4 Expression in Developing Incisor and Limb Bud

  2012cited by this paper
• Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production.

  2011cited by this paper
• Analysis of BMP4 and BMP7 signaling in breast cancer cells unveils time-dependent transcription patterns and highlights a common synexpression group of genes

  2011cited by this paper
• BMP-4 expression has prognostic significance in advanced serous ovarian carcinoma and is affected by cisplatin in OVCAR-3 cells

  2011cited by this paper
• mRNA Expression of Bone Morphogenetic Proteins and Their Receptors in Human Renal Cell Carcinoma

  2011cited by this paper
• Expression of bone morphogenic protein-4 is inversely related to prevalence of lymph node metastasis in gastric adenocarcinoma

  2011influential reference
• Bone morphogenetic protein -4 and -5 in pancreatic cancer--novel bidirectional players.

  2011cited by this paper
• BMP4 promotes prostate tumor growth in bone through osteogenesis.

  2011cited by this paper
• Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

  2011cited by this paper
• Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.

  2011cited by this paper
• Evaluation of Germline BMP4 Mutation as a Cause of Colorectal Cancer

  2011influential reference
• Identification of Common Differentially Expressed Genes in Urinary Bladder Cancer

  2011cited by this paper
• Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age‐related macular degeneration

  2011cited by this paper
• Bone morphogenetic protein-2 and -4 play tumor suppressive roles in human diffuse-type gastric carcinoma.

  2011cited by this paper
• Bone morphogenetic proteins: a critical review.

  2011cited by this paper
• Bone morphogenetic protein 4 (BMP4) is required for migration and invasion of breast cancer

  2011cited by this paper
• Effect of Bone Morphogenetic Protein 4 in the Human Brain Glioma Cell Line U251

  2010cited by this paper
• Parallel inhibition of cell growth and induction of cell migration and invasion in breast cancer cells by bone morphogenetic protein 4

  2010cited by this paper
• Hypoxia Regulates BMP4 Expression in the Murine Spleen during the Recovery from Acute Anemia

  2010cited by this paper
• Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart

  2010cited by this paper
• Pituitary tumors: cell type-specific roles for BMP-4.

  2010cited by this paper
• CpG island hypermethylation in human astrocytomas.

  2010cited by this paper
• Bone morphogenetic protein receptors and signal transduction.

  2010cited by this paper
• Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells

  2010cited by this paper
• An FGF4‐FRS2α‐Cdx2 Axis in Trophoblast Stem Cells Induces Bmp4 to Regulate Proper Growth of Early Mouse Embryos

  2009cited by this paper
• Bone morphogenetic protein 4 is induced in hepatocellular carcinoma by hypoxia and promotes tumour progression

  2009cited by this paper
• Control of BMP gene expression by long-range regulatory elements.

  2009cited by this paper
• A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling

  2009cited by this paper
• Bone Morphogenetic Protein 4 and Its Receptors Are Expressed in the Leptomeninges and Meningiomas and Signal via the Smad Pathway

  2009cited by this paper
• A predicted functional single-nucleotide polymorphism of bone morphogenetic protein-4 gene affects mRNA expression and shows a significant association with cutaneous melanoma in Southern Italian population

  2009cited by this paper
• Identification of an ancient Bmp4 mesoderm enhancer located 46 kb from the promoter.

  2009cited by this paper
• BMP4-Smad Signaling Pathway Mediates Adriamycin-induced Premature Senescence in Lung Cancer Cells*

  2009cited by this paper
• Bone morphogenetic proteins induce pancreatic cancer cell invasiveness through a Smad1-dependent mechanism that involves matrix metalloproteinase-2.

  2009cited by this paper
• Bone morphogenetic protein-4 induced by NDRG2 expression inhibits MMP-9 activity in breast cancer cells.

  2009cited by this paper
• Mutations in BMP4 are associated with subepithelial, microform, and overt cleft lip.

  2009cited by this paper
• Bone morphogenetic protein-4 strongly potentiates growth factor-induced proliferation of mammary epithelial cells.

  2008cited by this paper
• Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development.

  2008cited by this paper
• Role of the Transcriptional Corepressor Bcor in Embryonic Stem Cell Differentiation and Early Embryonic Development

  2008cited by this paper
• Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

  2008cited by this paper
• Bone morphogenetic proteins 1 to 7 in human breast cancer, expression pattern and clinical/prognostic relevance.

  2008cited by this paper
• Bone morphogenetic protein 4 induces epithelial‐mesenchymal transition through MSX2 induction on pancreatic cancer cell line

  2007cited by this paper
• Bone morphogenetic protein-4 inhibits heat-induced apoptosis by modulating MAPK pathways in human colon cancer HCT116 cells.

  2007cited by this paper
• BMP4 induces EMT and Rho GTPase activation in human ovarian cancer cells.

  2007cited by this paper
• Bone morphogenetic protein-4 abrogates lumen formation by mammary epithelial cells and promotes invasive growth.

  2007cited by this paper
• Expression of bone morphogenetic proteins, the subfamily of the transforming growth factor-beta superfamily, in renal cell carcinoma.

  2007cited by this paper
• A comprehensive expression survey of bone morphogenetic proteins in breast cancer highlights the importance of BMP4 and BMP7

  2007cited by this paper
• Bone morphogenetic protein-4 is overexpressed in colonic adenocarcinomas and promotes migration and invasion of HCT116 cells.

  2007influential reference
• Functional implication of BMP4 expression on angiogenesis in malignant melanoma

  2006cited by this paper
• Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity

  2006cited by this paper
• Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells

  2006cited by this paper
• Bone morphogenetic protein-4 inhibits corticotroph tumor cells: involvement in the retinoic acid inhibitory action.

  2006cited by this paper
• Genome-wide midrange transcription profiles reveal expression level relationships in human tissue specification

  2005cited by this paper
• Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration.

  2005cited by this paper
• SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS

  2005cited by this paper
• Influence of BMPs on the Formation of Osteoblastic Lesions in Metastatic Prostate Cancer

  2005cited by this paper
• Genome-wide aberrations in pancreatic adenocarcinoma.

  2005cited by this paper
• BMP4 signaling induces senescence and modulates the oncogenic phenotype of A549 lung adenocarcinoma cells.

  2004cited by this paper
• Restoration of Bone Morphogenetic Protein Receptor Type II Expression Leads to a Decreased Rate of Tumor Growth in Bladder Transitional Cell Carcinoma Cell Line TSU-Pr1

  2004cited by this paper
• Bone morphogenetic protein signaling in prostate cancer cell lines

  2004cited by this paper
• The bone morphogenetic protein system in mammalian reproduction.

  2004cited by this paper
• Signal transduction of bone morphogenetic protein receptors.

  2004cited by this paper
• Controlling cell fate by bone morphogenetic protein receptors.

  2003cited by this paper
• Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6.

  2003cited by this paper
• Identification of a putative autocrine bone morphogenetic protein-signaling pathway in human ovarian surface epithelium and ovarian cancer cells.

  2003cited by this paper
• GeneNote: whole genome expression profiles in normal human tissues.

  2003cited by this paper
• 14q(22) deletion in a familial case of anophthalmia with polydactyly

  2003cited by this paper
• Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells.

  2001cited by this paper
• Smads as transcriptional co-modulators.

  2000cited by this paper
• Linkage exclusion and mutational analysis of the noggin gene in patients with fibrodysplasia ossificans progressiva (FOP)

  2000cited by this paper
• Silencing of TGF-β signalling by the pseudoreceptor BAMBI

  1999cited by this paper
• Bone morphogenetic proteins‐2 and ‐4 attenuate apoptosis in a cerebellar primitive neuroectodermal tumor cell line

  1999cited by this paper
• Del(14)(q22.1q23.2) in a patient with anophthalmia and pituitary hypoplasia.

  1998cited by this paper
• BMP‐4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development

  1998cited by this paper
• The Human Bone Morphogenetic Protein 4 (BMP-4) Gene: Molecular Structure and Transcriptional Regulation

  1998cited by this paper
• Signal transduction by bone morphogenetic proteins.

  1998cited by this paper
• Transcriptional regulation of BMP-4 in the Xenopus embryo: analysis of genomic BMP-4 and its promoter.

  1998cited by this paper
• Transcriptional regulation of the mBMP-4 gene through an E-box in the 5'-flanking promoter region involving USF.

  1997cited by this paper
• Bone morphogenetic protein 2/4 in early fibromatous lesions of fibrodysplasia ossificans progressiva.

  1997cited by this paper
• Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva.

  1996cited by this paper
• Genomic organization of the human bone morphogenetic protein-4 gene: molecular basis for multiple transcripts.

  1996cited by this paper
• Regulation of dorsal-ventral patterning: the ventralizing effects of the novel Xenopus homeobox gene Vox.

  1996cited by this paper
• The Xvent-2 homeobox gene is part of the BMP-4 signalling pathway controling dorsoventral patterning of Xenopus mesoderm

  1996cited by this paper
• The Mouse Bone Morphogenetic Protein-4 Gene

  1995cited by this paper
• Cloning and sequence of bone morphogenetic protein 4 (BMP-4) from a human placental cDNA library.

  1995cited by this paper
• Congenital healed cleft lip.

  1995cited by this paper
• Osteogenic protein-1 (OP-1) expression and processing in Chinese hamster ovary cells: isolation of a soluble complex containing the mature and pro-domains of OP-1.

  1994cited by this paper
• Anophthalmia with cleft palate and micrognathia: a new syndrome?

  1994cited by this paper
• Murine bone morphogenetic protein-4 gene: existence of multiple promoters and exons for the 5'-untranslated region.

  1993cited by this paper
• A case of deletion 14(q22.1-->q22.3) associated with anophthalmia and pituitary abnormalities.

  1993cited by this paper

• Cell number in mesenchymal stem cell aggregates dictates cell stiffness and chondrogenesis

  2019cites this paper