The αβ T Cell Response to Self-Glycolipids Shows a Novel Mechanism of CD1b Loading and a Requirement for Complex Oligosaccharides

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Immunity

• Publication date

  2000-08-01

• Fields of study

  Biology

• Identifiers
  DOI 10.1016/S1074-7613(00)00025-X
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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• Crystal structure of an MHC class I presented glycopeptide that generates carbohydrate-specific CTL.

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• CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides.

  1997cited by this paper
• Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells.

  1997cited by this paper
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• Mouse CD1 is mainly expressed on hemopoietic-derived cells.

  1997cited by this paper
• Preparation of radiolabeled gangliosides.

  1996cited by this paper
• Cytoplasmic Tail-Dependent Localization of CD1b Antigen-Presenting Molecules to MIICs

  1996cited by this paper
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  1996cited by this paper
• A transient three-plasmid expression system for the production of high titer retroviral vectors.

  1995cited by this paper
• Aggregation properties of semisynthetic GD1a ganglioside (IV3Neu5AcII3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety.

  1995cited by this paper
• CD1-restricted T cell recognition of microbial lipoglycan antigens.

  1995cited by this paper
• Aggregative properties of gangliosides in solution.

  1994cited by this paper
• Geometrical and conformational properties of ganglioside GalNAc-GD1a, IV4GalNAcIV3Neu5AcII3Neu5AcGgOse4Cer.

  1994cited by this paper
• Recognition of a lipid antigen by GDI-restricted αβ+ T cells

  1994cited by this paper
• Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

  1994cited by this paper
• CDlb restricts the response of human CD4−8−T lymphocytes to a microbial antigen

  1992cited by this paper
• HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides.

  1992cited by this paper
• The CD1 system.

  1991cited by this paper
• Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line.

  1990cited by this paper
• Two classes of CD1 genes

  1989cited by this paper
• Semisynthetic preparation of N-glycolylneuraminic acid containing GM1 ganglioside: chemical characterization, physico-chemical properties and some biochemical features.

  1988cited by this paper
• Preparation of GM1 ganglioside molecular species having homogeneous fatty acid and long chain base moieties.

  1985cited by this paper
• Effect of modification of sialic acid on enzymic hydrolysis of gangliosides GM1 and GM2.

  1984cited by this paper
• Carbohydrate components of extraneuronal gangliosides from bovine and human spleen, and bovine kidney.

  1970cited by this paper

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• Molecular recognition of microbial lipid-based antigens by T cells

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• The intricacies of self‐lipid antigen presentation by CD1b

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• Contact sensitizers trigger human CD1‐autoreactive T‐cell responses

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• Group 1 CD1-restricted T cells and the pathophysiological implications of self-lipid antigen recognition.

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• Antigen Presentation by CD1 Lipids, T Cells, and NKT Cells in Microbial Immunity.

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• How T cells recognize lipids as antigens

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• How T cells get grip on lipid antigens.

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• Anti-GM1 antibodies as a model of the immune response to self-glycans.

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• Structure and biology of self lipid antigens.

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• Type II NKT cell-mediated anergy induction in type I NKT cells prevents inflammatory liver disease.

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  2006cites this paper
• Serum lipoproteins: Trojan horses of the immune response?

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• The surprising diversity of lipid antigens for CD1-restricted T cells.

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• Anatomy of CD1–lipid antigen complexes

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• T cell activation by lipopeptide antigens.

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