Calcium channel function regulated by the SH3-GK module in beta subunits.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Neuron

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  PMID 15066267
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• 3D domain swapping: As domains continue to swap

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• Structure and function of voltage-dependent ion channel regulatory beta subunits.

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• Structure of the SH3-guanylate kinase module from PSD-95 suggests a mechanism for regulated assembly of MAGUK scaffolding proteins.

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• SH3 domains: complexity in moderation.

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• Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95.

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• PDZ domains and the organization of supramolecular complexes.

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• Molecular Basis of Calmodulin Tethering and Ca2+-dependent Inactivation of L-type Ca2+ Channels*

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• hCASK and hDlg Associate in Epithelia, and Their Src Homology 3 and Guanylate Kinase Domains Participate in Both Intramolecular and Intermolecular Interactions*

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• Intramolecular interactions regulate SAP97 binding to GKAP

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• The [beta]2a subunit is a molecular groom for the Ca2+ channel inactivation gate.

  2000cited by this paper
• Structure and regulation of voltage-gated Ca2+ channels.

  2000cited by this paper
• Ca2+-sensitive Inactivation and Facilitation of L-type Ca2+ Channels Both Depend on Specific Amino Acid Residues in a Consensus Calmodulin-binding Motif in theα1C subunit*

  2000cited by this paper
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• Synaptic Localization and Presynaptic Function of Calcium Channel β4-Subunits in Cultured Hippocampal Neurons*

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• Acidic motif responsible for plasma membrane association of the voltage‐dependent calcium channel β1b subunit

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• The I-II loop of the Ca2+ channel alpha1 subunit contains an endoplasmic reticulum retention signal antagonized by the beta subunit.

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• Activation of channel activity of the NMDA receptor‐PSD‐95 complex by guanylate kinase‐associated protein (GKAP)

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• Modelling of a voltage‐dependent Ca2+ channel β subunit as a basis for understanding its functional properties

  1999cited by this paper
• Identification of the sites phosphorylated by cyclic AMP-dependent protein kinase on the beta 2 subunit of L-type voltage-dependent calcium channels.

  1999cited by this paper
• Interaction of NE-dlg/SAP102, a Neuronal and Endocrine Tissue-specific Membrane-associated Guanylate Kinase Protein, with Calmodulin and PSD-95/SAP90

  1999cited by this paper
• Association of Neuronal Calcium Channels with Modular Adaptor Proteins*

  1999cited by this paper
• Identification of an Intramolecular Interaction between the SH3 and Guanylate Kinase Domains of PSD-95*

  1999cited by this paper
• SAP90 binds and clusters kainate receptors causing incomplete desensitization.

  1998cited by this paper
• Subunit interaction sites in voltage-dependent Ca2+ channels: role in channel function.

  1998cited by this paper
• Unique regulatory properties of the type 2a Ca2+ channel beta subunit caused by palmitoylation.

  1998cited by this paper
• Localization of Postsynaptic Density-93 to Dendritic Microtubules and Interaction with Microtubule-Associated Protein 1A

  1998cited by this paper
• GKAP, a Novel Synaptic Protein That Interacts with the Guanylate Kinase-like Domain of the PSD-95/SAP90 Family of Channel Clustering Molecules

  1997cited by this paper
• Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large.

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• Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

  1996cited by this paper
• The C. elegans vulval induction gene lin-2 encodes a member of the MAGUK family of cell junction proteins.

  1996cited by this paper
• Reflections on Ca(2+)-channel diversity, 1988-1994.

  1995cited by this paper
• Roles of a Membrane-localized βSubunit in the Formation and Targeting of Functional L-type Ca2+ Channels (*)

  1995cited by this paper
• Calcium channel beta-subunit binds to a conserved motif in the I-II cytoplasmic linker of the alpha 1-subunit.

  1994cited by this paper
• Ca2+ channel regulation by a conserved beta subunit domain.

  1994cited by this paper
• Critical residues in an SH3 domain from Sem-5 suggest a mechanism for proline-rich peptide recognition

  1994cited by this paper
• Induction of calcium currents by the expression of the α1-subunit of the dihydropyridine receptor from skeletal muscle

  1989cited by this paper
• Subunit structure of dihydropyridine-sensitive calcium channels from skeletal muscle.

  1987cited by this paper
• Primary structure of the receptor for calcium channel blockers from skeletal muscle

  1987cited by this paper

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• [Structure of the calcium channel beta subunit: the place of the beta-interaction domain].

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