A MYB/bHLH complex regulates tissue-specific anthocyanin biosynthesis in the inner pericarp of red-centered kiwifruit Actinidia chinensis cv. Hongyang.

Many Actinidia cultivars are characterized by anthocyanin accumulation, specifically in the inner pericarp, but the underlying regulatory mechanism remains elusive. Here we report two interacting transcription factors, AcMYB123 and AcbHLH42, that regulate tissue-specific anthocyanin biosynthesis in the inner pericarp of Actinidia chinensis cv. Hongyang. Through transcriptome profiling analysis we identified five MYB and three bHLH transcription factors that were upregulated in the inner pericarp. We show that the combinatorial action of two of them, AcMYB123 and AcbHLH42, is required for activating promoters of AcANS and AcF3GT1 that encode the dedicated enzymes for anthocyanin biosynthesis. The presence of anthocyanin in the inner pericarp appears to be tightly associated with elevated expression of AcMYB123 and AcbHLH42. RNA interference repression of AcMYB123, AcbHLH42, AcF3GT1 and AcANS in 'Hongyang' fruits resulted in significantly reduced anthocyanin biosynthesis. Using both transient assays in Nicotiana tabacum leaves or Actinidia arguta fruits and stable transformation in Arabidopsis, we demonstrate that co-expression of AcMYB123 and AcbHLH42 is a prerequisite for anthocyanin production by activating transcription of AcF3GT1 and AcANS or the homologous genes. Phylogenetic analysis suggests that AcMYB123 or AcbHLH42 are closely related to TT2 or TT8, respectively, which determines proanthocyanidin biosynthesis in Arabidopsis, and to anthocyanin regulators in monocots rather than regulators in dicots. All these experimental results suggest that AcMYB123 and AcbHLH42 are the components involved in spatiotemporal regulation of anthocyanin biosynthesis specifically in the inner pericarp of kiwifruit.

• Publication year

  2019

• Venue

  The Plant Journal

• Publication date

  2019-04-29

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1111/tpj.14330PMID 30912865
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A manually annotated Actinidia chinensis var. chinensis (kiwifruit) genome highlights the challenges associated with draft genomes and gene prediction in plants

  2018influential reference
• The proanthocyanidin‐specific transcription factor MdMYBPA1 initiates anthocyanin synthesis under low‐temperature conditions in red‐fleshed apples

  2018cited by this paper
• Phytoplasmas–The “Crouching Tiger” Threat of Australian Plant Pathology

  2017influential reference
• Kiwifruit R2R3-MYB transcription factors and contribution of the novel AcMYB75 to red kiwifruit anthocyanin biosynthesis

  2017influential reference
• Expression Differences of Pigment Structural Genes and Transcription Factors Explain Flesh Coloration in Three Contrasting Kiwifruit Cultivars

  2017influential reference
• Map‐based cloning of the pear gene MYB114 identifies an interaction with other transcription factors to coordinately regulate fruit anthocyanin biosynthesis

  2017cited by this paper
• Characterization of Genes Encoding Key Enzymes Involved in Anthocyanin Metabolism of Kiwifruit during Storage Period

  2017influential reference
• DELLA Proteins Promote Anthocyanin Biosynthesis via Sequestering MYBL2 and JAZ Suppressors of the MYB/bHLH/WD40 Complex in Arabidopsis thaliana.

  2016cited by this paper
• The ubiquitin ligase SEVEN IN ABSENTIA (SINA) ubiquitinates a defense-related NAC transcription factor and is involved in defense signaling.

  2016cited by this paper
• Optimizing RNA-Seq Mapping with STAR.

  2016cited by this paper
• Comprehensive Transcriptome Profiling Reveals Long Noncoding RNA Expression and Alternative Splicing Regulation during Fruit Development and Ripening in Kiwifruit (Actinidia chinensis)

  2016cited by this paper
• Proteomic Analyses Provide Novel Insights into Plant Growth and Ginsenoside Biosynthesis in Forest Cultivated Panax ginseng (F. Ginseng)

  2016cited by this paper
• High-temperature inhibition of biosynthesis and transportation of anthocyanins results in the poor red coloration in red-fleshed Actinidia chinensis.

  2015influential reference
• Kiwifruit Information Resource (KIR): a comparative platform for kiwifruit genomics

  2015cited by this paper
• Transcriptional control of flavonoid biosynthesis by MYB-bHLH-WDR complexes.

  2015influential reference
• In the Solanaceae, a hierarchy of bHLHs confer distinct target specificity to the anthocyanin regulatory complex

  2015cited by this paper
• Trimmomatic: a flexible trimmer for Illumina sequence data

  2014cited by this paper
• Down-regulation of a LBD-like gene, OsIG1, leads to occurrence of unusual double ovules and developmental abnormalities of various floral organs and megagametophyte in rice

  2014cited by this paper
• Peace, a MYB-like transcription factor, regulates petal pigmentation in flowering peach ‘Genpei’ bearing variegated and fully pigmented flowers

  2014cited by this paper
• Overexpression of the kiwifruit SVP3 gene affects reproductive development and suppresses anthocyanin biosynthesis in petals, but has no effect on vegetative growth, dormancy, or flowering time

  2014cited by this paper
• Sucrose induction of anthocyanin biosynthesis is mediated by DELLA.

  2014cited by this paper
• A Conserved Network of Transcriptional Activators and Repressors Regulates Anthocyanin Pigmentation in Eudicots[C][W][OPEN]

  2014cited by this paper
• A role for PacMYBA in ABA-regulated anthocyanin biosynthesis in red-colored sweet cherry cv. Hong Deng (Prunus avium L.).

  2014cited by this paper
• Transcriptional regulation of secondary metabolite biosynthesis in plants.

  2013cited by this paper
• Identification and characterization of MYB-bHLH-WD40 regulatory complexes controlling proanthocyanidin biosynthesis in strawberry (Fragaria × ananassa) fruits.

  2013influential reference
• An R2R3 MYB transcription factor determines red petal colour in an Actinidia (kiwifruit) hybrid population

  2013influential reference
• The MrWD40-1 Gene of Chinese Bayberry (Myrica rubra) Interacts with MYB and bHLH to Enhance Anthocyanin Accumulation

  2013cited by this paper
• Draft genome of the kiwifruit Actinidia chinensis

  2013influential reference
• Isolation and characterization of GtMYBP3 and GtMYBP4, orthologues of R2R3-MYB transcription factors that regulate early flavonoid biosynthesis, in gentian flowers

  2012cited by this paper
• The tomato UV-damaged DNA-binding protein-1 (DDB1) is implicated in pathogenesis-related (PR) gene expression and resistance to Agrobacterium tumefaciens.

  2012cited by this paper
• Identification and characterization of MYB-bHLH-WD 40 regulatory complexes controlling proanthocyanidin biosynthesis in strawberry ( Fragaria 9 ananassa ) fruits

  2012influential reference
• SERE: Single-parameter quality control and sample comparison for RNA-Seq

  2012cited by this paper
• The apple WD40 protein MdTTG1 interacts with bHLH but not MYB proteins to regulate anthocyanin accumulation.

  2012cited by this paper
• The bHLH transcription factor MdbHLH3 promotes anthocyanin accumulation and fruit colouration in response to low temperature in apples.

  2012cited by this paper
• MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods.

  2011influential reference
• Evolutionary and comparative analysis of MYB and bHLH plant transcription factors.

  2011cited by this paper
• Recent advances in the transcriptional regulation of the flavonoid biosynthetic pathway.

  2011cited by this paper
• Identification and characterisation of F3GT1 and F3GGT1, two glycosyltransferases responsible for anthocyanin biosynthesis in red-fleshed kiwifruit (Actinidia chinensis).

  2011cited by this paper
• A pomegranate (Punica granatum L.) WD40-repeat gene is a functional homologue of Arabidopsis TTG1 and is involved in the regulation of anthocyanin biosynthesis during pomegranate fruit development

  2011cited by this paper
• Coordinated regulation of anthocyanin biosynthesis in Chinese bayberry (Myrica rubra) fruit by a R2R3 MYB transcription factor

  2010cited by this paper
• Isolation of WDR and bHLH genes related to flavonoid synthesis in grapevine (Vitis vinifera L.)

  2010cited by this paper
• Transcript assembly and abundance estimation from RNA-Seq reveals thousands of new transcripts and switching among isoforms

  2010cited by this paper
• A conserved unusual posttranscriptional processing mediated by short, direct repeated (SDR) sequences in plants.

  2010cited by this paper
• The basic helix-loop-helix transcription factor MYC1 is involved in the regulation of the flavonoid biosynthesis pathway in grapevine.

  2010cited by this paper
• Anthocyanin biosynthesis in pears is regulated by a R2R3-MYB transcription factor PyMYB10

  2010cited by this paper
• Ascorbate Biosynthesis during Early Fruit Development Is the Main Reason for Its Accumulation in Kiwi

  2010cited by this paper
• Characterization and quantification of anthocyanins in red kiwifruit ( Actinidia spp.).

  2009cited by this paper
• A Novel Cation-Dependent O-Methyltransferase Involved in Anthocyanin Methylation in Grapevine1[C][W][OA]

  2009cited by this paper
• Biochemical and molecular characterization of plant MYB transcription factor family

  2009cited by this paper
• Ectopic expression of VlmybA1 in grapevine activates a narrow set of genes involved in anthocyanin synthesis and transport

  2009cited by this paper
• Isolation and structural identification of the anthocyanin components of red kiwifruit.

  2009cited by this paper
• AtMYBL2, a protein with a single MYB domain, acts as a negative regulator of anthocyanin biosynthesis in Arabidopsis.

  2008cited by this paper
• MYBL2 is a new regulator of flavonoid biosynthesis in Arabidopsis thaliana.

  2008cited by this paper
• The Transcription Factor VvMYB5b Contributes to the Regulation of Anthocyanin and Proanthocyanidin Biosynthesis in Developing Grape Berries12[W]

  2008cited by this paper
• Regulation of the anthocyanin biosynthetic pathway by the TTG1/bHLH/Myb transcriptional complex in Arabidopsis seedlings.

  2008cited by this paper
• Redirection of Flavonoid Biosynthesis through the Down-Regulation of an Anthocyanidin Glucosyltransferase in Ripening Strawberry Fruit1[W][OA]

  2008cited by this paper
• Nutrient depletion as a key factor for manipulating gene expression and product formation in different branches of the flavonoid pathway.

  2008cited by this paper
• Differential regulation of closely related R2R3-MYB transcription factors controls flavonol accumulation in different parts of the Arabidopsis thaliana seedling

  2007cited by this paper
• Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis

  2007cited by this paper
• Nitrogen deficiency enhances expression of specific MYB and bHLH transcription factors and accumulation of end products in the flavonoid pathway

  2007cited by this paper
• White grapes arose through the mutation of two similar and adjacent regulatory genes.

  2007cited by this paper
• The N-terminal region of Pseudomonas type III effector AvrPtoB elicits Pto-dependent immunity and has two distinct virulence determinants.

  2007cited by this paper
• The genetics and biochemistry of floral pigments.

  2006cited by this paper
• TT8 controls its own expression in a feedback regulation involving TTG1 and homologous MYB and bHLH factors, allowing a strong and cell-specific accumulation of flavonoids in Arabidopsis thaliana.

  2006cited by this paper
• Light-Induced Expression of a MYB Gene Regulates Anthocyanin Biosynthesis in Red Apples1

  2006cited by this paper
• Tt8 Controls Its Own Expression in a Feedback Regulation Involving Ttg1 and Homologous Myb and Bhlh Factors, Allowing a Strong and Cell-specific Accumulation of Flavonoids in Arabidopsis Thaliana

  2006cited by this paper
• The Arabidopsis Transcription Factor MYB12 Is a Flavonol-Specific Regulator of Phenylpropanoid Biosynthesis1

  2005cited by this paper
• Pigments in the fruit of red-fleshed kiwifruit (Actinidia chinensis and Actinidia deliciosa).

  2005cited by this paper
• Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor.

  2005cited by this paper
• Flavonoids: a colorful model for the regulation and evolution of biochemical pathways.

  2005cited by this paper
• Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.

  2004cited by this paper
• Mutations in the pale aleurone color1 Regulatory Gene of the Zea mays Anthocyanin Pathway Have Distinct Phenotypes Relative to the Functionally Similar TRANSPARENT TESTA GLABRA1 Gene in Arabidopsis thaliana On-line version contains Web-only data.

  2004cited by this paper
• Visualization of protein interactions in living plant cells using bimolecular fluorescence complementation.

  2004cited by this paper
• TT2, TT8, and TTG1 synergistically specify the expression of BANYULS and proanthocyanidin biosynthesis in Arabidopsis thaliana.

  2004influential reference
• Multiple sequence alignment with the Clustal series of programs

  2003cited by this paper
• Complete sequence of the binary vector pBI121 and its application in cloning T-DNA insertion from transgenic plants

  2003cited by this paper
• Role of Anthocyanidin Reductase, Encoded by BANYULS in Plant Flavonoid Biosynthesis

  2003cited by this paper
• Anthocyanin biosynthetic genes are coordinately expressed during red coloration in apple skin

  2002cited by this paper
• Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

  2001cited by this paper
• The Arabidopsis TT2 Gene Encodes an R2R3 MYB Domain Protein That Acts as a Key Determinant for Proanthocyanidin Accumulation in Developing Seed

  2001cited by this paper
• Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology.

  2001cited by this paper
• In vivo analysis of plant promoters and transcription factors by agroinfiltration of tobacco leaves.

  2000cited by this paper
• The TT8 Gene Encodes a Basic Helix-Loop-Helix Domain Protein Required for Expression of DFR and BAN Genes in Arabidopsis Siliques

  2000cited by this paper
• Construction and selection of the novel recombinant Escherichia coli strain for poly(beta-hydroxybutyrate) production.

  2000cited by this paper
• Identification of the residues in the Myb domain of maize C1 that specify the interaction with the bHLH cofactor R.

  2000influential reference
• Activation Tagging Identifies a Conserved MYB Regulator of Phenylpropanoid Biosynthesis

  2000cited by this paper
• The BANYULS gene encodes a DFR-like protein and is a marker of early seed coat development.

  1999cited by this paper
• Multifunctionality and diversity within the plant MYB-gene family

  1999cited by this paper
• Plant cis-acting regulatory DNA elements (PLACE) database: 1999

  1999cited by this paper
• Phenolic composition of kiwifruit juice.

  1999cited by this paper
• The TRANSPARENT TESTA GLABRA1 Locus, Which Regulates Trichome Differentiation and Anthocyanin Biosynthesis in Arabidopsis, Encodes a WD40 Repeat Protein

  1999cited by this paper
• Analysis of bHLH and MYB domain proteins: species-specific regulatory differences are caused by divergent evolution of target anthocyanin genes.

  1998cited by this paper
• Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana.

  1998cited by this paper
• The an11 locus controlling flower pigmentation in petunia encodes a novel WD-repeat protein conserved in yeast, plants, and animals.

  1997cited by this paper
• Analysis of the Expression of Anthocyanin Pathway Genes in Developing Vitis vinifera L. cv Shiraz Grape Berries and the Implications for Pathway Regulation

  1996cited by this paper
• Controlling the false discovery rate: a practical and powerful approach to multiple testing

  1995cited by this paper
• Lc, a member of the maize R gene family responsible for tissue-specific anthocyanin production, encodes a protein similar to transcriptional activators and contains the myc-homology region.

  1989cited by this paper
• Two regulatory genes of the maize anthocyanin pathway are homologous: isolation of B utilizing R genomic sequences.

  1989cited by this paper
• PLANT REPORTER GENES: THE GUS GENE FUSION SYSTEM

  1988cited by this paper
• The neighbor-joining method: a new method for reconstructing phylogenetic trees.

  1987cited by this paper

• Genetic, biochemical and molecular characterization of Amrapali/Vanraj mango (Mangifera indica L.) hybrids for peel and pulp color

  2026cites this paper
• Genome-Wide Identification of R2R3-MYB Family Members and Identification of AaMYB1/AaMYB36 Linked to Peel Coloration in Northern Red-Peel Actinidia arguta

  2026cites this paper
• The Mechanism of TT2-Type MYB Transcription Factor JrMYB1L in Anthocyanin Biosynthesis in ‘Jinghong 1’ Walnuts

  2025cites this paper
• Comprehensive analysis of bHLH transcription factors reveals candidate regulators of flower development and heat stress response in Rhododendron simsii

  2025cites this paper
• High-quality genome assembly of autotetraploid Verbena bonariensis sheds light on flower color development

  2025cites this paper
• The transcription factor MYB78 negatively regulates cold stress tolerance in Actinidia chinensis.

  2025cites this paper
• Metabolome and Transcriptome Reveal the Regulatory Mechanism of Anthocyanin Synthesis in Tuber Skin and Flesh of Dioscorea alata L.

  2025cites this paper
• A key bHLH transcription factor, CsbHLH18, negatively regulates catechin biosynthesis in response to water stress

  2025cites this paper
• Truncated CMV2bN43 enhances virus-induced gene silencing in pepper by retaining systemic but not local silencing suppression

  2025cites this paper
• Advancements in the Regulation of Flavonoid Compounds in Monocotyledons and Dicotyledons by Plant MYB Transcription Factors

  2025cites this paper
• Genetic Regulation of Anthocyanin Biosynthesis in Cornus Species: The Roles of R2R3‐MYB Transcription Factors

  2025cites this paper
• Regulatory mechanism of anthocyanin biosynthesis in Dendrobium officinale : Integrating metabolome and transcriptome to reveal the potential application for quality improvement

  2025cites this paper
• PavbHLH102 functions as a positive regulator of anthocyanin biosynthesis in sweet cherry fruit by targeting multiple key genes

  2025cites this paper
• McACO2 gene promotes ethylene-mediated scopoletin biosynthesis in noni (Morinda citrifolia).

  2025cites this paper
• Study on the dynamics of fruits color related genes and metabolites during the fruit development of Zanthoxylum bungeanum ‘Hanyuan’

  2025cites this paper
• Integrated transcriptome and metabolome analysis reveals flavor quality regulations in post-harvest fruits of Actinidia melanandra

  2025cites this paper
• Combination of 3D chromatin architecture and omics analysis provides insight into anthocyanin regulation in Actinidia arguta

  2025cites this paper
• Natural variation of AcEGY3 mediates chloroplastic ROS homeostasis to confer kiwifruit thermotolerance

  2025cites this paper
• bHLH291 Regulates Anthocyanin Accumulation in Kiwifruit Under Bagging Treatment

  2025cites this paper
• Ectopic expression of strawberry FaMADS6 represses anthocyanin biosynthesis in both tobacco and Arabidopsis thaliana.

  2025cites this paper
• Exogenous 5-aminolevulinic acid enhances the quality and anthocyanin synthesis ability of fig fruit

  2025cites this paper
• Functional analysis of AobHLH88 involved in anthocyanin synthesis using multi-omics data in Asparagus officinalis.

  2025cites this paper
• Iron deficiency specifically activated anthocyanin accumulation in out pericarp of red-fleshed kiwifruit (Actinidia chinensis)

  2025cites this paper
• Integrated Transcriptomics and Metabolomics Reveal Key Genes and Metabolic Pathway in Flower and Fruit Color Formation of Cerasus humilis (Bge.) Sok

  2025cites this paper
• Chromosome-level genome assembly assisting for dissecting mechanism of anthocyanin regulation in kiwifruit (Actinidia arguta)

  2025influential citation
• Transcription Factor VvbHLH137 Positively Regulates Anthocyanin Accumulation in Grape (Vitis vinifera)

  2025cites this paper
• Orchestrating anthocyanin biosynthesis in fruit of fruit trees: Transcriptional, post-transcriptional, and post-translational regulation.

  2025cites this paper
• CaMYBA–CaMYC–CaTTG1 complex activates the transcription of anthocyanin synthesis structural genes and regulates anthocyanin accumulation in pepper (Capsicum annuum L.) leaves

  2025cites this paper
• AaEIL2 and AaERF059 are involved in fruit coloration and ripening by crossly regulating ethylene and auxin signal pathway in Actinidia arguta

  2025cites this paper
• Two AcMYB22 Alleles Differently Regulate Flavonoid Biosynthesis Resulting in Varied Flesh Color in Kiwifruit.

  2025cites this paper
• cDNA Cloning, Bioinformatics, and Expression Analysis of ApsANS in Acer pseudosieboldianum

  2025cites this paper
• Development and application of a Ginkgo biloba L. callus-derived protoplast transient expression system for exploring the roles of GbMYB11 and GbbHLH3 in flavonoid metabolism

  2025cites this paper
• Flavones enrich rhizosphere Pseudomonas to enhance nitrogen utilization and secondary root growth in Populus

  2025cites this paper
• Light regulates SlCOP1-mediated degradation of SlJAF13, a transcription factor essential for anthocyanin biosynthesis in Aft tomato fruit.

  2025cites this paper
• Transcriptomic and metabolomic analyses reveal the mechanism of color difference between two kinds of Cistanche deserticola before and after drying

  2025cites this paper
• AaMYB61-like and AabHLH137 jointly regulate anthocyanin biosynthesis in Actinidia arguta

  2025cites this paper
• Comprehensive analysis of metabolomics and transcriptomics reveals varied tepal pigmentation across Gloriosa varieties

  2025cites this paper
• Emerging Trends in Secondary Metabolite Research in Caryophyllales: Betalains and Their Roles in Plant Adaptation and Defense Mechanisms.

  2025cites this paper
• Analysis of WD40 genes in kiwifruit reveals the key role of the light-induced AcTTG1-AcMYB75-AcbHLH2 complex in anthocyanin accumulation.

  2025cites this paper
• Metabolomic and transcriptomic analyses provide insights into temperature and light regulated anthocyanin accumulation in flesh of ‘Furongli’ plum (Prunus salicina Lindl.)

  2025cites this paper
• AcGLK1 promotes chloroplast division through regulating AcFtsZ1 in Actinidia chinensis

  2024cites this paper
• Kiwifruit spatiotemporal multiomics networks uncover key tissue-specific regulatory processes throughout the life cycle.

  2024cites this paper
• Transcriptomic and metabolomic insights into temperature-dependent changes in catechin and anthocyanin accumulation in tea plants with different leaf colors

  2024cites this paper
• Comparative transcriptome analysis and transient assays revealed AaGST and AaBGAL, respectively, contribute to skin and flesh coloration in A. arguta.

  2024cites this paper
• DcbHLH1 interacts with DcMYB1 and DcMYB2 to dynamically regulate petal pigmentation in Dianthus caryophyllus

  2024cites this paper
• The R2R3-MYB Transcriptional Repressor TgMYB4 Negatively Regulates Anthocyanin Biosynthesis in Tulips (Tulipa gesneriana L.)

  2024cites this paper
• Genome-Wide Association Study of Sweet Potato Storage Root Traits Using GWASpoly, a Gene Dosage-Sensitive Model

  2024cites this paper
• Integrated Analysis of Transcriptome and Metabolome Provides Insights into Flavonoid Biosynthesis of Blueberry Leaves in Response to Drought Stress

  2024cites this paper
• Regulatory mechanisms of miR171d–SCL6 module in the rooting process of Acer rubrum L.

  2024cites this paper
• Unveiling the Effect of EDTA and SA in Mustard under Cd and Pb Stress

  2024cites this paper
• Transcriptomic and metabolomic analyses reveal molecular and metabolic regulation of anthocyanin biosynthesis in three varieties of currant.

  2024cites this paper
• Elucidation of AsANS controlling pigment biosynthesis in Angelica sinensis through hormonal and transcriptomic analysis.

  2024cites this paper
• LvbHLH13 Regulates Anthocyanin Biosynthesis by Activating the LvMYB5 Promoter in Lily (Lilium ‘Viviana’)

  2024cites this paper
• QTL mapping of fruit quality traits in tetraploid kiwiberry (Actinidia arguta)

  2024cites this paper
• Multiplex Approach of Metabolomic and Transcriptomic Reveals the Biosynthetic Mechanism of Light-induced Flavonoids and CGA in Chrysanthemum

  2024cites this paper
• Synergistic actions of three MYB transcription factors underpin blotch formation in tree peony.

  2024cites this paper
• Decoding anthocyanin biosynthesis regulation in Asparagus officinalis peel coloration: Insights from integrated metabolomic and transcriptomic analyses.

  2024cites this paper
• Combined Metabolomic and Transcriptomic Analysis Reveals Candidate Genes for Anthocyanin Accumulation in Ginkgo biloba Seed Exocarp

  2024cites this paper
• Graph‐Based Pangenome of Actinidia chinensis Reveals Structural Variations Mediating Fruit Degreening

  2024cites this paper
• Genome-Wide Analysis of Transcription Factor R2R3-MYB Gene Family and Gene Expression Profiles during Anthocyanin Synthesis in Common Walnut (Juglans regia L.)

  2024cites this paper
• Recent advances of kiwifruit genome and genetic transformation

  2024cites this paper
• Promoter replication of grape MYB transcription factor is associated with a new red flesh phenotype

  2024cites this paper
• A Fruit-Expressed MYB Transcription Factor Regulates Anthocyanin Biosynthesis in Atropa belladonna

  2024cites this paper
• Integrated Metabolomic and Transcriptomic Profiles Provide Insights into the Mechanisms of Anthocyanin and Carotenoid Biosynthesis in Petals of Medicago sativa ssp. sativa and Medicago sativa ssp. falcata

  2024cites this paper
• Banana MabHLH28 positively regulates the expression of softening-related genes to mediate fruit ripening independently or via cooperating with MaWRKY49/111

  2024cites this paper
• MdbHLH162 connects the gibberellin and jasmonic acid signals to regulate anthocyanin biosynthesis in apple.

  2024cites this paper
• AcMYB10 Involved in Anthocyanin Regulation of ‘Hongyang’ Kiwifruit Induced via Fruit Bagging and High-Postharvest-Temperature Treatments

  2024cites this paper
• Integrative metabolome and transcriptome analyses reveal the coloration mechanism in Camellia oleifera petals with different color

  2024cites this paper
• Genome wide association analysis identifies candidate genes for fruit quality and yield in Actinidia eriantha1

  2023cites this paper
• Identification of basic helix-loop-helix transcription factors that activate betulinic acid biosynthesis by RNA-sequencing of hydroponically cultured Lotus japonicus

  2023cites this paper
• A MYB transcription factor containing fragment introgressed from Gossypium bickii confers pink flower on Gossypium hirsutum L.

  2023cites this paper
• Characterization and Analysis of the Full-Length Transcriptome Provide Insights into Fruit Quality Formation in Kiwifruit Cultivar Actinidia arguta cv. Qinziyu

  2023cites this paper
• Characterization of Highbush Blueberry (Vaccinium corymbosum L.) Anthocyanin Biosynthesis Related MYBs and Functional Analysis of VcMYB Gene

  2023cites this paper
• Characterization of Transcriptome Dynamics during Early Fruit Development in Olive (Olea europaea L.)

  2023cites this paper
• Integrated metabolome and transcriptome analysis reveals the cause of anthocyanin biosynthesis deficiency in litchi aril.

  2023cites this paper
• Integrated Transcriptome and Metabolome Analyses Provide Insights into the Coloring Mechanism of Dark-red and Yellow Fruits in Chinese Cherry [Cerasus pseudocerasus (Lindl.) G. Don]

  2023cites this paper
• Insights into flavonoid biosynthesis during cucumber fruit peel coloration based on metabolite profiling and transcriptome analyses

  2023cites this paper
• Integrated transcriptomics and metabolomics analysis provide insight into anthocyanin biosynthesis for sepal color formation in Heptacodium miconioides

  2023cites this paper
• FaMYB123 interacts with FabHLH3 to regulate the late steps of anthocyanin and flavonol accumulation during ripening.

  2023cites this paper
• A comprehensive metabolic map reveals major quality regulations in red flesh kiwifruit (Actinidia chinensis).

  2023cites this paper
• Isolation and Activity Analysis of Phytoene Synthase (ClPsy1) Gene Promoter of Canary-Yellow and Golden Flesh-Color Watermelon

  2023cites this paper
• Identification and functional characterization of AcMYB113 in anthocyanin metabolism of Aesculus chinensis Bunge var. chinensis leaves.

  2023cites this paper
• A dramatic decline in fruit citrate induced by mutagenesis of a NAC transcription factor, AcNAC1

  2023cites this paper
• Transcriptomic and metabolomic analysis of autumn leaf color change in Fraxinus angustifolia

  2023cites this paper
• CaWRKY50 Acts as a Negative Regulator in Response to Colletotrichum scovillei Infection in Pepper

  2023cites this paper
• Transcription factors TgbHLH42-1 and TgbHLH42-2 positively regulate anthocyanin biosynthesis in Tulip (Tulipa gesneriana L.).

  2023cites this paper
• Integrative analysis of metabolome and transcriptome reveals the mechanism of color formation in cassava (Manihot esculenta Crantz) leaves

  2023cites this paper
• Independent flavonoid and anthocyanin biosynthesis in the flesh of a red-fleshed table grape revealed by metabolome and transcriptome co-analysis

  2023cites this paper
• Integrative Metabolome and Transcriptome Analyses Reveal the Molecular Mechanism of Yellow-Red Bicolor Formation in Kalanchoe blossfeldiana Petals

  2023cites this paper
• Designing plant flavonoids: harnessing transcriptional regulation and enzyme variation to enhance yield and diversity

  2023cites this paper
• Functional characterization of 2-oxoglutarate-dependent dioxygenase gene family in chickpea.

  2023cites this paper
• AcHZP45 is a repressor of chlorophyll biosynthesis and activator of chlorophyll degradation in kiwifruit.

  2023cites this paper
• Recent advances in stability improvement of anthocyanins by efficient methods and its application in food intelligent packaging: A review

  2023cites this paper
• The Collaborative Role of the Regulatory (MYB-bHLH-WD40) and Structural Genes Results in Fruit Coloration in Plants Some Do This Under the Influence of External Stimuli

  2023cites this paper
• Transcriptome and metabolome analyses of anthocyanin biosynthesis in post-harvest fruits of a full red-type kiwifruit (Actinidia arguta) ‘Jinhongguan’

  2023cites this paper
• Genome-Wide Identification of PAP1 Direct Targets in Regulating Seed Anthocyanin Biosynthesis in Arabidopsis

  2023cites this paper
• The CsMYB123 and CsbHLH111 are involved in drought stress-induced anthocyanin biosynthesis in Chaenomeles speciosa

  2023cites this paper
• A Novel R2R3–MYB Transcription Factor FaMYB10-like Promotes Light-Induced Anthocyanin Accumulation in Cultivated Strawberry

  2023cites this paper
• Methylation of AcGST1 Is Associated with Anthocyanin Accumulation in the Kiwifruit Outer Pericarp.

  2023cites this paper
• FvDFR2 rather than FvDFR1 play key roles for anthocyanin synthesis in strawberry petioles.

  2023cites this paper