Immunity‐targeted approaches to the management of chronic and recurrent upper respiratory tract disorders in children

W. Feleszko,Ricardo Marengo,António Vieira,Karol Ratajczak,J. L. Mayorga Butrón

Published 2019 in Clinical Otolaryngology

ABSTRACT

Upper respiratory tract infections (URTIs), including rhinitis, nasopharyngitis, tonsillitis and otitis media (OM), comprise of 88% of total respiratory infections, especially in children. Therefore effective prevention and treatment of RTIs remain a high priority worldwide. Preclinical and clinical data highlight the rationale for the use and effectiveness of immunity‐targeted approaches, including targeted immunisations and non‐specific immunomodulation in the prevention and management of recurrent upper RTIs.

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