The success of pregnancy depends on a receptive endometrium, a normal blastocyst, a synchronized cross-talk at the maternal–fetal interface at the time of implantation, and finally a successful placentation and remodeling of uterine vasculature. In routine, less than 5% of oocytes collected in in vitro fertilization (IVF) cycles and only 20 to 25% of embryos transferred lead to a birth. Implantation and placentation processes remain the black box of fertility, involving following steps: fertilization, endometrial receptivity, embryo implantation (apposition-adhesion-invasion), trophoblastic differentiation and invasion (Cartwright et al., 2010).
The actors of human implantation: gametes, embryo and endometrium
Virginie Gridelet,O. Gaspard,B. Polese,P. Ruggeri,S. Ravet,C. Munaut,V. Geenen,J. Foidart,N. Lédée,S. P. d’Hauterive
Published 2012 in Unknown venue
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- Publication year
2012
- Venue
Unknown venue
- Publication date
2012-03-30
- Fields of study
Biology, Medicine
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