SCIENCE@home

Skin tissue engineering

D. Wong,Howard Y. Chang

Published 2009 in Stembook

ABSTRACT

The skin is the largest organ of the body and is critical to survival of the organism as a barrier to the environment and for thermal regulation and hydration retention. In order to serve these critical functions, the skin is constantly undergoing renewal and possesses the capacity for repair of wounds, which are dependent on the multiple types of stem cells in the skin. Engineered skin substitutes have a critical medical application to patients with extensive burn wounds. However, current skin substitutes do not restore the normal skin anatomy, lacking the normal appendages of skin including hair follicles, sebaceous glands, and sweat glands as well as the normal mechanical properties of the skin. Advances in stem cell biology and skin morphogenesis hold promise for the ability to markedly improve the engineering of skin substitutes that would ideally be indistinguishable from normal skin.

PUBLICATION RECORD

CITATION MAP

EXTRACTION MAP

CLAIMS

  • No claims are published for this paper.

CONCEPTS

  • No concepts are published for this paper.

REFERENCES

Showing 1-43 of 43 references · Page 1 of 1

CITED BY

Showing 1-16 of 16 citing papers · Page 1 of 1