Beyond the Channel: Role of Connexins in Regulating Normal and Cancerous Processes in the Mammary Gland

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/978-94-017-7380-5_1
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Role of connexins in metastatic breast cancer and melanoma brain colonization

  2013cited by this paper
• Mortalin antibody-conjugated quantum dot transfer from human mesenchymal stromal cells to breast cancer cells requires cell-cell interaction.

  2013cited by this paper
• Gap junction proteins on the move: connexins, the cytoskeleton and migration.

  2013cited by this paper
• Context dependent reversion of tumor phenotype by connexin-43 expression in MDA-MB231 cells and MCF-7 cells: role of β-catenin/connexin43 association.

  2013cited by this paper
• Polarity proteins as regulators of cell junction complexes: implications for breast cancer.

  2013cited by this paper
• Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice

  2012cited by this paper
• Stochastic 16-state model of voltage gating of gap-junction channels enclosing fast and slow gates.

  2012cited by this paper
• Estrogens promote cell-cell adhesion of normal and malignant mammary cells through increased desmosome formation.

  2012cited by this paper
• The perinexus: a new feature of Cx43 gap junction organization.

  2012cited by this paper
• On cell-matrix interactions in mammary gland development and breast cancer.

  2012cited by this paper
• Update on mammography trends

  2011cited by this paper
• Breast on-a-chip: mimicry of the channeling system of the breast for development of theranostics.

  2011cited by this paper
• Organ printing: from bioprinter to organ biofabrication line.

  2011cited by this paper
• Cx43 suppresses mammary tumor metastasis to the lung in a Cx43 mutant mouse model of human disease

  2011cited by this paper
• Connexins and the gap in context.

  2011cited by this paper
• Intercellular Communication by Exchange of Cytoplasmic Material via Tunneling Nano-Tube Like Structures in Primary Human Renal Epithelial Cells

  2011cited by this paper
• CXCL12 secretion by bone marrow stromal cells is dependent on cell contact and mediated by connexin-43 and connexin-45 gap junctions

  2011cited by this paper
• Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy.

  2011cited by this paper
• Mutations in connexin genes and disease

  2011cited by this paper
• Connexins: a junctional crossroad to breast cancer.

  2011cited by this paper
• From milk to malignancy: the role of mammary stem cells in development, pregnancy and breast cancer

  2011cited by this paper
• Extracellular Matrix Composition Reveals Complex and Dynamic Stromal-Epithelial Interactions in the Mammary Gland

  2010cited by this paper
• The gap junction proteome and its relationship to disease.

  2010cited by this paper
• Attenuation of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced gap junctional intercellular communication (GJIC) inhibition in MCF-10A cells by c9,t11-conjugated linoleic acid.

  2010cited by this paper
• Functional microRNA is transferred between glioma cells.

  2010cited by this paper
• Second-generation substituted quinolines as anticancer drugs for breast cancer.

  2010cited by this paper
• Connexin 43 is critical to maintain the homeostasis of the blood–testis barrier via its effects on tight junction reassembly

  2010cited by this paper
• Diversity and properties of connexin gap junction channels.

  2010cited by this paper
• Combinational treatment of gap junctional activator and tamoxifen in breast cancer cells

  2010cited by this paper
• pH-dependent modulation of voltage gating in connexin45 homotypic and connexin45/connexin43 heterotypic gap junctions

  2010cited by this paper
• Contributions of extracellular matrix signaling and tissue architecture to nuclear mechanisms and spatial organization of gene expression control.

  2009cited by this paper
• Involvement of the Cytoplasmic C-Terminal Domain of Connexin43 in Neuronal Migration

  2009cited by this paper
• Connexins: a myriad of functions extending beyond assembly of gap junction channels

  2009cited by this paper
• Collective cell migration in morphogenesis, regeneration and cancer

  2009cited by this paper
• Increased claudin‐4 expression is associated with poor prognosis and high tumour grade in breast cancer

  2009cited by this paper
• Loss of tight junction barrier function and its role in cancer metastasis.

  2009cited by this paper
• Tight Junctions: A Barrier to the Initiation and Progression of Breast Cancer?

  2009cited by this paper
• Tight junctions as targets of infectious agents.

  2009cited by this paper
• Gap junctional intercellular communication in hypoxia-ischemia-induced neuronal injury.

  2008cited by this paper
• The neuronal connexin36 interacts with and is phosphorylated by CaMKII in a way similar to CaMKII interaction with glutamate receptors

  2008cited by this paper
• Organization of multiprotein complexes at cell–cell junctions

  2008cited by this paper
• Structure and function of claudins.

  2008cited by this paper
• Regulation of neuronal connexin-36 channels by pH

  2008cited by this paper
• Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia.

  2008cited by this paper
• Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling

  2008cited by this paper
• Heterocellular interaction enhances recruitment of alpha and beta-catenins and ZO-2 into functional gap-junction complexes and induces gap junction-dependant differentiation of mammary epithelial cells.

  2008cited by this paper
• Connexin-43 upregulation in micrometastases and tumor vasculature and its role in tumor cell attachment to pulmonary endothelium

  2008cited by this paper
• Contact Inhibition of Locomotion in vivo controls neural crest directional migration

  2008cited by this paper
• Connexins and Gap Junctions in Mammary Gland Development and Breast Cancer Progression

  2007cited by this paper
• Involvement of the ubiquitous Oct-1 transcription factor in hormonal induction of beta-casein gene expression.

  2007cited by this paper
• Nature of Cx30-containing channels in the adult mouse mammary gland

  2007cited by this paper
• Gap junction channel gating modulated through protein phosphorylation.

  2007cited by this paper
• Gap junctional complexes: from partners to functions.

  2007cited by this paper
• The role of junctional adhesion molecules in vascular inflammation

  2007cited by this paper
• JAM family and related proteins in leukocyte migration (Vestweber series).

  2007cited by this paper
• Promotion of lens epithelial-fiber differentiation by the C-terminus of connexin 45.6 – a role independent of gap junction communication

  2007cited by this paper
• Regulation of Renal Cell Carcinoma Cell Proliferation, Invasion and Metastasis by Connexin 32 Gene

  2007cited by this paper
• Connexin channel permeability to cytoplasmic molecules.

  2007cited by this paper
• Structure and function of desmosomes.

  2007cited by this paper
• The stage-specific function of gap junctions during tumourigenesis

  2007cited by this paper
• Gap junction channel structure in the early 21st century: facts and fantasies.

  2007cited by this paper
• Permeability of homotypic and heterotypic gap junction channels formed of cardiac connexins mCx30.2, Cx40, Cx43, and Cx45.

  2007cited by this paper
• Pathways and control of connexin oligomerization

  2006cited by this paper
• Cx26 inhibits breast MDA-MB-435 cell tumorigenic properties by a gap junctional intercellular communication-independent mechanism.

  2006cited by this paper
• Plasma membrane sterol distribution resembles the surface topography of living cells.

  2006cited by this paper
• Connexin 43-mediated modulation of polarized cell movement and the directional migration of cardiac neural crest cells

  2006cited by this paper
• Life cycle of connexins in health and disease.

  2006cited by this paper
• Increased expression of connexins 26 and 43 in lymph node metastases of breast cancer

  2006cited by this paper
• The gap junction cellular internet: connexin hemichannels enter the signalling limelight.

  2006cited by this paper
• Possible involvement of gap junctions in the barrier function of tight junctions of brain and lung endothelial cells

  2006cited by this paper
• Dimerization of the Scaffolding Protein ZO-1 through the Second PDZ Domain*

  2006cited by this paper
• Connexins and their channels in cell growth and cell death.

  2006cited by this paper
• Endocytic processing of connexin43 gap junctions: a morphological study.

  2006cited by this paper
• Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin.

  2005cited by this paper
• The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

  2005cited by this paper
• Down-regulation of Cx43 by retroviral delivery of small interfering RNA promotes an aggressive breast cancer cell phenotype.

  2005cited by this paper
• Correlative studies of gating in Cx46 and Cx50 hemichannels and gap junction channels.

  2005cited by this paper
• Role of gap junctions during early embryo development.

  2005cited by this paper
• Key stages of mammary gland development: Molecular mechanisms involved in the formation of the embryonic mammary gland

  2005cited by this paper
• Cadherins and catenins in breast cancer.

  2005cited by this paper
• Role of gap junctional intercellular communication (GJIC) through p38 and ERK1/2 pathway in the differentiation of rat neuronal stem cells.

  2005cited by this paper
• High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells

  2005cited by this paper
• Connexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in culture

  2005cited by this paper
• Junctional Adhesion Molecule 1 Regulates Epithelial Cell Morphology through Effects on β1 Integrins and Rap1 Activity*

  2005cited by this paper
• Cadherins and the mammary gland

  2005cited by this paper
• Gap junctions and connexin-interacting proteins.

  2004cited by this paper
• Loss of connexin 26 in mammary epithelium during early but not during late pregnancy results in unscheduled apoptosis and impaired development.

  2004cited by this paper
• Coordinated expression of desmoglein 1 and desmocollin 1 regulates intercellular adhesion.

  2004cited by this paper
• Junctional adhesion molecules (JAMs): more molecules with dual functions?

  2004cited by this paper
• Chemical gating of gap junction channels; roles of calcium, pH and calmodulin.

  2004cited by this paper
• Prespecification and plasticity: shifting mechanisms of cell migration.

  2004cited by this paper
• Developmental expression patterns and regulation of connexins in the mouse mammary gland: expression of connexin30 in lactogenesis

  2004cited by this paper
• Immunophenotypic analysis of inflammatory breast cancers: identification of an ‘inflammatory signature’

  2004cited by this paper
• Altered permeability and modulatory character of connexin channels during mammary gland development.

  2004cited by this paper
• Gap junctions and the connexin protein family.

  2004cited by this paper
• The permeability of gap junction channels to probes of different size is dependent on connexin composition and permeant-pore affinities.

  2004cited by this paper
• The carboxy-tail of connexin-43 localizes to the nucleus and inhibits cell growth

  2004cited by this paper
• Reexpression of the TJ protein CLDN1 induces apoptosis in breast tumor spheroids

  2004cited by this paper
• Drebrin is a novel connexin-43 binding partner that links gap junctions to the submembrane cytoskeleton.

  2004cited by this paper
• Connexins and cell signaling in development and disease.

  2004cited by this paper

• A risk progression breast epithelial 3D culture model reveals Cx43/hsa_circ_0077755/miR-182 as a biomarker axis for heightened risk of breast cancer initiation

  2021cites this paper
• Connexin43 as a Tumor Suppressor: Proposed Connexin43 mRNA-circularRNAs-microRNAs Axis Towards Prevention and Early Detection in Breast Cancer

  2019cites this paper