Mechanism of 4-Hydroxynonenal induced toxicity in Jurkat CD4+ T lymphocytes.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.18297/ETD/232
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• S-Adenosylmethionine

  2020cited by this paper
• p38 MAPK regulates phosphorylation of Bad via PP2A-dependent suppression of the MEK1/2-ERK1/2 survival pathway in TNF-alpha induced endothelial apoptosis.

  2006cited by this paper
• Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.

  2006cited by this paper
• Glutathione depletion renders rat hepatocytes sensitive to nitric oxide donor–mediated toxicity

  2005cited by this paper
• Up-regulation of glutathione biosynthesis in NIH3T3 cells transformed with the ETV6-NTRK3 gene fusion.

  2005cited by this paper
• Distinct Protein Phosphatase 2A Heterotrimers Modulate Growth Factor Signaling to Extracellular Signal-regulated Kinases and Akt*

  2005cited by this paper
• Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer.

  2005cited by this paper
• Isoflurane Inhibits Cardiac Myocyte Apoptosis during Oxidative and Inflammatory Stress by Activating Akt and Enhancing Bcl-2 Expression

  2005cited by this paper
• Akt inhibition upregulates FasL, downregulates c-FLIPs and induces caspase-8-dependent cell death in Jurkat T lymphocytes

  2005cited by this paper
• FLICE/caspase-8 activation triggers anoikis induced by β1-integrin blockade in human keratinocytes

  2004cited by this paper
• Induction of redox imbalance and apoptosis in multiple myeloma cells by the novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid.

  2004cited by this paper
• p‐Aminophenol‐induced hepatotoxicity in hamsters: Role of glutathione

  2004cited by this paper
• Homocysteine Enhances Endothelial Apoptosis via Upregulation of Fas-Mediated Pathways

  2004cited by this paper
• A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells

  2004cited by this paper
• The CD95(APO-1/Fas) DISC and beyond

  2003cited by this paper
• Visualization of the compartmentalization of glutathione and protein‐glutathione mixed disulfides in cultured cells

  2003cited by this paper
• Eicosapentaenoic Acid Protects Endothelial Cells Against Anoikis Through Restoration of cFLIP

  2003cited by this paper
• Protein Kinase B Activation by Reactive Oxygen Species Is Independent of Tyrosine Kinase Receptor Phosphorylation and Requires Src Activity*

  2003cited by this paper
• Eicosapentaenoic Acid Protects Endothelial Cells Against Anoikis Through Restoration of cFLIP

  2003cited by this paper
• Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal

  2003cited by this paper
• 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress.

  2003cited by this paper
• Glutaredoxin Exerts an Antiapoptotic Effect by Regulating the Redox State of Akt*

  2003cited by this paper
• The death effector domain protein family: regulators of cellular homeostasis

  2003cited by this paper
• Nerve Growth Factor Protects against 6-Hydroxydopamine-induced Oxidative Stress by Increasing Expression of Heme Oxygenase-1 in a Phosphatidylinositol 3-Kinase-dependent Manner*

  2003cited by this paper
• Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: new partners in TCR/CD28 signal integration.

  2002cited by this paper
• Probucol preserves pancreatic beta-cell function through reduction of oxidative stress in type 2 diabetes.

  2002cited by this paper
• Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.

  2002cited by this paper
• Long-term ethanol administration enhances age-dependent modulation of redox state in different brain regions in the rat: protection by acetyl carnitine.

  2002cited by this paper
• Acetaminophen-induced suppression of hepatic AdoMet synthetase activity is attenuated by prodrugs of L-cysteine.

  2002cited by this paper
• Redox Imbalance and Its Control in HIV Infection

  2002cited by this paper
• Suppression of Akt Signaling Induces Fas Ligand Expression: Involvement of Caspase and Jun Kinase Activation in Akt-Mediated Fas Ligand Regulation

  2002cited by this paper
• S‐Adenosylmethionine: a control switch that regulates liver function

  2002cited by this paper
• Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes.

  2002cited by this paper
• Methylpyridinium (MPP(+))- and nerve growth factor-induced changes in pro- and anti-apoptotic signaling pathways in SH-SY5Y neuroblastoma cells.

  2002cited by this paper
• N-Ethylmaleimide Inhibits Platelet-derived Growth Factor BB-stimulated Akt Phosphorylation via Activation of Protein Phosphatase 2A*

  2002cited by this paper
• FLICE-Inhibitory Proteins: Regulators of Death Receptor-Mediated Apoptosis

  2001cited by this paper
• Cellular FLICE-inhibitory Protein Splice Variants Inhibit Different Steps of Caspase-8 Activation at the CD95 Death-inducing Signaling Complex*

  2001cited by this paper
• Effects of 2(RS)-n-propylthiazolidine-4(R)-carboxylic acid on extrahepatic sulfhydryl levels in mice treated with acetaminophen.

  2001cited by this paper
• Phosphatidylinositol 3-Kinase/Akt Signaling Controls Endothelial Cell Sensitivity to Fas-Mediated Apoptosis via Regulation of FLICE-Inhibitory Protein (FLIP)

  2001cited by this paper
• Evidence of Phosphorylation of Akt and Neuronal Survival after Transient Focal Cerebral Ischemia in Mice

  2001cited by this paper
• c-myb Transcription Is Activated by Protein Kinase B (PKB) following Interleukin 2 Stimulation of T Cells and Is Required for PKB-Mediated Protection from Apoptosis

  2001cited by this paper
• The role of c-Myb in the up-regulation of methionine adenosyltransferase 2A expression in activated Jurkat cells.

  2001cited by this paper
• 4-hydroxynonenal induces a cellular redox status-related activation of the caspase cascade for apoptotic cell death.

  2000cited by this paper
• Blood glutathione decreases in chronic diseases.

  2000cited by this paper
• 4-Hydroxynonenal, an end-product of lipid peroxidation, induces apoptosis in human leukemic T- and B-cell lines

  2000cited by this paper
• Fas mediates apoptosis and oxidant-induced cell death in cultured hRPE cells.

  2000cited by this paper
• S-Adenosylmethionine and Pneumocystis carinii *

  2000cited by this paper
• Dietary vitamin E and T cell‐mediated function in the elderly: effectiveness and mechanism of action

  2000cited by this paper
• Differential effects of L-buthionine sulfoximine and ethacrynic acid on glutathione levels and mitochondrial function in PC12 cells.

  1999cited by this paper
• Forkhead transcription factors: new insights into protein kinase B (c-akt) signaling

  1999cited by this paper
• Survival- and Death-Promoting Events after Transient Cerebral Ischemia: Phosphorylation of Akt, Release of Cytochrome C, and Activation of Caspase-Like Proteases

  1999cited by this paper
• Sequence Selectivity of c-Myb in Vivo

  1999cited by this paper
• Determination of 4-hydroxy-2-nonenal at cellular levels by means of electrospray mass spectrometry.

  1999cited by this paper
• The myb gene family in cell growth, differentiation and apoptosis

  1999cited by this paper
• Regulation of Fas-Ligand Expression during Activation-induced Cell Death in T Lymphocytes via Nuclear Factor κB*

  1999cited by this paper
• Protection of CD95‐mediated apoptosis by activation of phosphatidylinositide 3‐kinase and protein kinase B

  1998cited by this paper
• Alcohol abuse, alcoholism, and damage to the immune system--a review.

  1998cited by this paper
• Regulation of cell death protease caspase-9 by phosphorylation.

  1998cited by this paper
• Comparison of Seven Quantitative Assays to Assess Lymphocyte Cell Death during HIV Infection: Measurement of Induced Apoptosis in Anti-Fas-Treated Jurkat Cells and Spontaneous Apoptosis in Peripheral Blood Mononuclear Cells from Children Infected with HIV

  1998cited by this paper
• Alcohol decreases T-lymphocyte migration into lung tissue in response to Pneumocystis carinii and depletes T-lymphocyte numbers in the spleens of mice.

  1998cited by this paper
• Involvement of APO2 ligand/TRAIL in activation‐induced death of Jurkat and human peripheral blood T cells

  1998cited by this paper
• Lipid peroxidation products and antioxidants in human disease.

  1998cited by this paper
• Regulation of Protein Phosphatase 2A Activity by Caspase-3 during Apoptosis*

  1998cited by this paper
• Genetic Diversity and Tissue Compartmentalization of the Hepatitis C Virus Genome in Blood Mononuclear Cells, Liver, and Serum from Chronic Hepatitis C Patients

  1998cited by this paper
• Redox signaling and the emerging therapeutic potential of thiol antioxidants.

  1998cited by this paper
• Protective effects of anethole dithiolethione against oxidative stress-induced cytotoxicity in human Jurkat T cells.

  1998cited by this paper
• The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2.

  1998cited by this paper
• Alcohol-induced thymocyte apoptosis is accompanied by impaired mitochondrial function.

  1997influential reference
• Inhibition of death receptor signals by cellular FLIP

  1997cited by this paper
• Differential Regulation of Methionine Adenosyltransferase in Superantigen and Mitogen Stimulated Human T Lymphocytes*

  1997cited by this paper
• Evidence that 4-Hydroxynonenal Mediates Oxidative Stress-Induced Neuronal Apoptosis

  1997cited by this paper
• Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery.

  1997cited by this paper
• Modulation of human T lymphocyte proliferation by 4-hydroxynonenal, the bioactive product of neutrophil-dependent lipid peroxidation.

  1997cited by this paper
• Modification of aldose reductase by S-nitrosoglutathione.

  1997cited by this paper
• Nutritional biochemistry of cellular glutathione

  1997cited by this paper
• S-adenosylmethionine synthesis: molecular mechanisms and clinical implications.

  1997cited by this paper
• FLICE is activated by association with the CD95 death‐inducing signaling complex (DISC)

  1997cited by this paper
• Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt.

  1997cited by this paper
• 4-hydroxynonenal specifically inhibits c-myb but does not affect c-fos expressions in HL-60 cells.

  1996cited by this paper
• Casein kinase II phosphorylation site mutations in c-Myb affect DNA binding and transcriptional cooperativity with NF-M

  1995cited by this paper
• Chromosomal Localization and Catalytic Properties of the Recombinant α Subunit of Human Lymphocyte Methionine Adenosyltransferase (*)

  1995cited by this paper
• Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

  1995cited by this paper
• APO‐1(CD95)‐mediated apoptosis in Jurkat cells does not involve src kinases or CD45

  1995cited by this paper
• Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

  1995cited by this paper
• The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase.

  1995cited by this paper
• FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.

  1995cited by this paper
• Protein phosphorylation in apoptosis.

  1995cited by this paper
• Glutathione Precursor and Antioxidant Activities of N-Acetylcysteine and Oxothiazolidine Carboxylate Compared in in Vitro Studies of HIV Replication

  1994cited by this paper
• Monitoring oxidative damage in patients with liver cirrhosis and different daily alcohol intake.

  1994cited by this paper
• Methionine adenosyltransferase: structure and function.

  1993cited by this paper
• Reduction of a conserved Cys is essential for Myb DNA-binding.

  1992cited by this paper
• Induction of interleukin 2 production but not methionine adenosyltransferase activity or S-adenosylmethionine turnover in Jurkat T-cells.

  1992cited by this paper
• Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation.

  1992cited by this paper
• S‐adenosylmethionine treatment prevents carbon tetrachloride—induced S‐adenosylmethionine synthetase inactivation and attenuates liver injury

  1992cited by this paper
• Tumor necrosis factor in alcohol enhanced endotoxin liver injury.

  1992cited by this paper
• Glutathione dependent metabolism and detoxification of 4-hydroxy-2-nonenal.

  1991cited by this paper
• Induction of differentiation in human HL-60 cells by 4-hydroxynonenal, a product of lipid peroxidation.

  1991cited by this paper
• Possible sources of iron for lipid peroxidation.

  1991cited by this paper
• Inhibition of glutathione synthesis in the liver leads to S‐adenosyl‐L‐methionine synthetase reduction

  1991cited by this paper
• Alcohol-induced oxidative stress in rat liver.

  1991cited by this paper

• Effects of 2(RS)-n-propylthiazolidine-4(R)-carboxylic acid on 4-hydroxy-2-nonenal-induced apoptotic T cell death.

  2008cites this paper