Identification of a signal transducer and activator of transcription (STAT) binding site in the mouse metallothionein-I promoter involved in interleukin-6-induced gene expression.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Biochemical Journal

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1042/BJ3370059PMID 9854025PMCID PMC1219936
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• STATs and gene regulation.

  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
• Blocking effect of anti-mouse interleukin-6 monoclonal antibody and glucocorticoid receptor antagonist, RU38486, on metallothionein-inducing activity of serum from lipopolysaccharide-treated mice.

  1996cited by this paper
• Activation of the complete mouse metallothionein gene locus in the maternal deciduum

  1996cited by this paper
• A central role for Stat3 in IL‐6‐induced regulation of growth and differentiation in M1 leukemia cells.

  1996cited by this paper
• STAT3 Participates in Transcriptional Activation of the C-reactive Protein Gene by Interleukin-6 (*)

  1996cited by this paper
• Induction of heme oxygenase-1 gene expression by lipopolysaccharide is mediated by AP-1 activation.

  1995cited by this paper
• Transcriptional regulation by extracellular signals: mechanisms and specificity.

  1995cited by this paper
• Transcriptional responses to polypeptide ligands: the JAK-STAT pathway.

  1995cited by this paper
• Functional analysis of IL-6 and IL-6DBP/C/EBP beta by gene targeting.

  1995cited by this paper
• Temporalspatial patterns of expression of metallothionein-I and -III and other stress related genes in rat brain after kainic acid-induced seizures.

  1995cited by this paper
• Antioxidative roles of metallothionein and manganese superoxide dismutase induced by tumor necrosis factor-alpha and interleukin-6.

  1995cited by this paper
• Characterization of the IL-6 Responsive Elements in the γ Fibrinogen Gene Promoter (*)

  1995cited by this paper
• Cytokine signal transduction.

  1994cited by this paper
• Epidermal growth factor and lipopolysaccharide activate Stat3 transcription factor in mouse liver.

  1994cited by this paper
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  1994cited by this paper
• Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

  1994cited by this paper
• The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein.

  1994cited by this paper
• Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway.

  1994cited by this paper
• Differential induction of metallothionein synthesis by interleukin-6 and tumor necrosis factor-alpha in rat tissues.

  1994cited by this paper
• Differential requirements for p21ras and protein kinase C in the regulation of neuronal gene expression by nerve growth factor and neurokines.

  1994cited by this paper
• Mechanisms of endotoxin-induced haem oxygenase mRNA accumulation in mouse liver: synergism by glutathione depletion and protection by N-acetylcysteine.

  1994cited by this paper
• n-hexane-induced synthesis of hepatic metallothionein is mediated by IL-6 in mouse.

  1994cited by this paper
• The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family

  1994cited by this paper
• Establishment of the role of IL‐6 and TNF receptor 1 using gene knockout mice

  1994cited by this paper
• The acute phase response.

  1994cited by this paper
• Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements.

  1994cited by this paper
• Impaired immune and acute-phase responses in interleukin-6-deficient mice

  1994cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
• Endotoxin induction of hepatic metallothionein is mediated through cytokines.

  1991cited by this paper
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  1991cited by this paper
• Endotoxin induction of murine metallothionein gene expression.

  1990cited by this paper
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  1990cited by this paper
• Regulation of manganese superoxide dismutase by lipopolysaccharide, interleukin-1, and tumor necrosis factor. Role in the acute inflammatory response.

  1990cited by this paper
• Interleukin 6 regulates metallothionein gene expression and zinc metabolism in hepatocyte monolayer cultures.

  1990cited by this paper
• Regulation of metallothionein gene expression.

  1990cited by this paper
• Interleukin-6 and the acute phase response.

  1990cited by this paper
• Constitutive and metal-inducible protein:DNA interactions at the mouse metallothionein I promoter examined by in vivo and in vitro footprinting.

  1988cited by this paper
• Physiological role of glucocorticoids on rat serum and liver metallothionein in basal and stress conditions.

  1988cited by this paper
• Tissue‐specific regulation of zinc metabolism and metallothionein genes by interleukin 1

  1988cited by this paper
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  1988cited by this paper
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  1985cited by this paper
• Glucocorticoid independent mediation of interleukin-1 induced changes in serum zinc and liver metallothionein levels.

  1984cited by this paper
• Induction of mouse metallothionein-I mRNA by bacterial endotoxin is independent of metals and glucocorticoid hormones.

  1984cited by this paper
• Involvement of hepatic metallothioneins in hypozincemia associated with bacterial infection.

  1978cited by this paper
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  1970cited by this paper

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