The Anatomy and Histology of Caudal Autotomy and Regeneration in Lizards*

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Physiological and Biochemical Zoology

• Publication date

  2013-10-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1086/673889PMID 24241061
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Unique Structural Features Facilitate Lizard Tail Autotomy

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• Wounding in lizards results in the release of beta-defensins at the wound site and formation of an antimicrobial barrier.

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• A Histological Comparison of the Original and Regenerated Tail in the Green Anole, Anolis carolinensis

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• Histology and histochemistry of the gekkotan notochord and their bearing on the development of notochordal cartilage

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• Morphological and biochemical analyses of original and regenerated lizard tails reveal variation in protein and lipid composition.

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• Time-varying motor control of autotomized leopard gecko tails: multiple inputs and behavioral modulation

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• Wound Repair and Regeneration

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• Scar‐Free Wound Healing and Regeneration Following Tail Loss in the Leopard Gecko, Eublepharis macularius

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  2011cited by this paper
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  2011cited by this paper
• Mouse digit tip regeneration is mediated by fate-restricted progenitor cells

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• A novel amniote model of epimorphic regeneration: the leopard gecko, Eublepharis macularius

  2011cited by this paper
• Gecko CD59 Is Implicated in Proximodistal Identity during Tail Regeneration

  2011cited by this paper
• Immunolocalization of FGF1 and FGF2 in the regenerating tail of the lizard Lampropholis guichenoti: implications for FGFs as trophic factors in lizard tail regeneration.

  2010cited by this paper
• Regulation of proximal‐distal intercalation during limb regeneration in the axolotl (Ambystoma mexicanum)

  2010cited by this paper
• Evolution of animal regeneration: re-emergence of a field.

  2010cited by this paper
• Ultrastructural changes in skeletal muscle of the tail of the lizard Hemidactylus mabouia immediately following autotomy

  2010cited by this paper
• Autoradiographic observations on developing and growing claws of reptiles

  2010influential reference
• Essays and Observations On Natural History, Anatomy, Physiology, Psychology, and Geology

  2010cited by this paper
• Reptile scale paradigm: Evo-Devo, pattern formation and regeneration.

  2009cited by this paper
• Cells keep a memory of their tissue origin during axolotl limb regeneration

  2009cited by this paper
• Aspects of vertebral development in lizards and snakes

  2009cited by this paper
• Morphological and cellular aspects of tail and limb regeneration in lizards. A model system with implications for tissue regeneration in mammals.

  2009cited by this paper
• Losing stability: tail loss and jumping in the arboreal lizard Anolis carolinensis

  2009cited by this paper
• To cut a long tail short: a review of lizard caudal autotomy studies carried out over the last 20 years

  2009cited by this paper
• How regenerating lymphatics function: Lessons from lizard tails

  2007cited by this paper
• Principles of Regenerative Biology

  2007cited by this paper
• Apoptosis is required during early stages of tail regeneration in Xenopus laevis.

  2007cited by this paper
• The Role of Defensin NP-1 in Restoring the Functions of an Injured Nerve Trunk

  2006cited by this paper
• Thyroid Hormone Control of Tail Regeneration: Differential in Loco and Systemic Effects and Seasonal Variation

  2006cited by this paper
• Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish

  2006cited by this paper
• Regeneration, tissue injury and the immune response

  2006cited by this paper
• The costs of autotomy and regeneration in animals: a review and framework for future research

  2006cited by this paper
• Wound keratins in the regenerating epidermis of lizard suggest that the wound reaction is similar in the tail and limb.

  2005cited by this paper
• Understanding the role of immune regulation in wound healing.

  2004cited by this paper
• Adaptation to the land: The skin of reptiles in comparison to that of amphibians and endotherm amniotes.

  2003cited by this paper
• Regenerating lizard tails: A new model for investigating lymphangiogenesis

  2003cited by this paper
• PHYSIOLOGY OF ORIGINAL AND REGENERATED LIZARD TAILS

  2002cited by this paper
• Maximal Caudal Autotomy in Podarcis hispanica (Lacertidae): The Caudofemoralis Muscle Is Not Sundered

  2001cited by this paper
• Apical epithelial cap morphology and fibronectin gene expression in regenerating axolotl limbs

  2000cited by this paper
• Plastic changes and nitric oxide synthase induction in neurons that innervate the regenerated tail of the lizard Gekko gecko: I. Response of spinal motoneurons to tail amputation and regeneration

  2000cited by this paper
• Comparative cell morphology in the peripheral blood film from exotic and native animals.

  1998cited by this paper
• Morphological and morphometrical changes in dorsal root ganglion neurons innervating the regenerated lizard tail

  1998cited by this paper
• Local and systemic alterations in cyclic 3′,5′ AMP phosphodiesterase activity in relation to tail regeneration under hypothyroidism and T4 replacement in the lizard, Mabuya carinata

  1996cited by this paper
• A conceptual framework for analyzing axial patterning in regenerating urodele limbs.

  1996cited by this paper
• Muscle differentiation and morphogenesis in the regenerating tail of lizards.

  1995influential reference
• Wound repair and regeneration

  1994cited by this paper
• Fine structure of cells in the young regenerating spinal cord of the lizard Anolis carolinensis after H3-thymidine administration.

  1992cited by this paper
• Axonal sprouting and frank regeneration in the lizard tail spinal cord: Correlation between changes in synaptic circuitry and axonal growth

  1992cited by this paper
• Glial Cell Composition and Ultrastructure of the Caudal Spinal Cord of Young and Adult Tuataras, Sphenodon punctatus

  1992cited by this paper
• Skin mechanics and morphology in Sphaerodactylus roosevelti (Reptilia: Gekkonidae)

  1992cited by this paper
• Fine observation on nerves colonizing the regenerating tail of the lizard Podarcis sicula.

  1990cited by this paper
• Origin of spinal cord axons in the lizard regenerated tail: Supernormal projections from local spinal neurons

  1990cited by this paper
• Fine structure of regenerating caudal spinal cord in adult tuatara (Sphenodon punctatus).

  1990cited by this paper
• Mechanical Properties and Morphological Correlates of Fragile Skin in Gekkonid Lizards

  1989cited by this paper
• Fine structure of the blastema in the regenerating tail of the lizard Podarcis sicula

  1988influential reference
• Regulation of vertebrate limb regeneration

  1985cited by this paper
• Evolutionary aspects of tail shedding in lizards and their relatives

  1984cited by this paper
• Nerve supply as a stimulator of the growth of tissues including skin *

  1978cited by this paper
• Nerve supply as a stimulator of the growth of tissues including skin *

  1978cited by this paper
• Detection of myosin in prefusion G0 lizard myoblasts in vitro.

  1977cited by this paper
• Satellite cells in mature, uninjured skeletal muscle of the lizard tail.

  1974cited by this paper
• When? Why? and How? Some Speculations on the Evolution of the Vertebrate Integument

  1972cited by this paper
• The role of ependyma in spinal cord regeneration in the urodele, Triturus.

  1972cited by this paper
• Studies on regeneration of the lizard's tail.

  1970cited by this paper
• The growth and differentiation of the regenerating spinal cord of the lizard, Anolis carolinensis

  1970cited by this paper
• Some aspects of tail regeneration in the lizard, Anolis carolinensis. I. A description based on histology and autoradiography.†,‡

  1969cited by this paper
• Morphology of the regenerated spinal cord in the lizard, Anolis carolinensis

  1968cited by this paper
• Lizard Caudal Vertebrae

  1967influential reference
• Regeneration of the Caudal Axial Skeleton in a Gekkonid Lizard (Hemidactylus) with Particular Reference to the ‘Latent’ Period

  1967cited by this paper
• THE REGENERATIVE CAPACITY OF THE TAIL IN EMBRYONIC AND POST-NATAL LIZARDS (LACERTA VIVIPARA JACQUIN).

  1964cited by this paper
• Analysis of tail regeneration in the lizard Lygosoma laterale. I. Initiation of regeneration and cartilage differentiation: The role of ependyma

  1964cited by this paper
• THE COMPARATIVE MORPHOLOGY OF THE AXIAL SKELETON IN THE AUSTRALIAN GEKKONIDAE

  1960cited by this paper
• Tail regeneration in the geckonid lizard, Sphaerodactylus.

  1959cited by this paper
• The effect of apical cap removal on limb regeneration in Amblystoma larvae.

  1957cited by this paper
• The influence of the spinal cord in regeneration of the tail of the lizard, Anolis carolinensis†

  1955influential reference
• Studies on the comparative anatomy of the tail in sauria and rhynchocephalia

  1941cited by this paper
• The effect of temperature on the scale form of regenerated lizard skin

  1933cited by this paper
• Memoirs: Some Observations on Caudal Autotomy and Regeneration in the Gecko (Hemidactylus flaviviridis, Rppel), with Notes on the Tails of Sphenodon and Pygopus

  1920cited by this paper

• A hydrodynamic antenna: novel lateral line system in the tail of myliobatid stingrays

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• Sall Genes and Proteins Activation during Early Tail and Limb Regeneration in the Lizard Podarcis muralis Suggests Dedifferentiation

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• Microscopic and ultrastructural observations on the regenerating scales of the lizard Podarcis muralis clarify the origin of the micro-ornamentation

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• Histological and Immunohistochemical Analyses on the Formation of the Split Plane in Developing Autotomous Tail Vertebrae of the Lizard Anolis lineatopus

  2025cites this paper
• Caudal autotomy in Mesosaurus tenuidens Gervais, 1865 under scrutiny and a surprising new pattern of vertebral organization in the mesosaur tail

  2025cites this paper
• Immune Activation Following Spinal Cord Injury: A Review Focused on Inflammatory Changes in the Spinal Cord

  2025cites this paper
• Review. The regenerating tail of lizards contains tumor suppressors RNAs and proteins that inhibit cancer cell proliferation.

  2025cites this paper
• The Price of Tail Loss: Implications of Caudal Autotomy and Regeneration on Male Social Hierarchies in a Territorial Lacertid Lizard

  2025cites this paper
• Human Footprint Halves Tail Loss Rates in Geckos Worldwide

  2025cites this paper
• BIFURCACIÓN DE LA COLA EN DOS LAGARTIJAS NEOTROPICALES COMUNES: Ctenosaura similis (GRAY, 1831) Y Gonatodes albogularis (DUMÉRIL & BIBRON, 1836)

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• The evolutionary origin and mechanism of chordate tail regeneration. An ancient tale?

  2024cites this paper
• Body size estimation from isolated fossil bones reveals deep time evolutionary trends in North American lizards

  2024cites this paper
• Immunolocalization of lix1 in the regenerating tail of lizard indicates that the protein is mainly present in the nervous tissue.

  2023cites this paper
• Tail bifurcation in Chinese blue-tailed skink Plestiodon chinensis (Gray, 1839)

  2023cites this paper
• Effectivity of Shark Cartilage (Carcharhinus sorrah) Ointment Extract on Growth of Lizard (Mabouya multifasciata kuhl) Regenerated Tail

  2023cites this paper
• Protein extracts from regenerating lizard tail show an inhibitory effect on human cancer cells cultivated in-vitro.

  2023cites this paper
• Immunolocalization of CD3 , CD5 and MHCII in amputated tail and limb of the lizard Podarcis muralis marks a scarring healing program

  2023cites this paper
• Microscopical observations on the regenerating tail of tsinling dwarf skink (Scincella tsinlingensis).

  2022cites this paper
• Gecko-inspired ultrasensitive multifunctional mechano-optical smart membranes

  2022cites this paper
• Physiological Effects of Tail Regeneration following Autotomy in Italian Wall Lizards, Podarcis siculus

  2022cites this paper
• Immunolocalization of tumor suppressors arhgap28 and retinoblastoma in the lizard Podarcis muralis suggests that they contribute to the regulated regeneration of the tail

  2022cites this paper
• Immunolocalization of adenomatous polyposis coli protein (apc) in the regenerating lizard tail suggests involvement in tissue differentiation and regulation of growth

  2022influential citation
• Tail regeneration in the gecko Sphaerodactylus argus shows that the formation of an axial elastic skeleton is functional for the new tail

  2022cites this paper
• Unique histological features of the tail skin of cotton rat (Sigmodon hispidus) related to caudal autotomy

  2021cites this paper
• Introduction to the Study on Regeneration in Lizards as an Amniote Model of Organ Regeneration

  2021cites this paper
• Microscopy suggests that glutathione S‐transferase is stored in large granules of myeloid cells in bone marrow and sparse granulocytes of the regenerating tail of lizard

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• Effects of Caudal Autotomy on the Locomotor Performance of Micrablepharus Atticolus (Squamata, Gymnophthalmidae)

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• Self-Control of Inflammation during Tail Regeneration of Lizards

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• The vascularization, innervation and myogenesis of early regenerated tail in Gekko japonicus

  2021cites this paper
• Spinal ganglia and peripheral nerves innervating the regenerating tail and muscles of lizards

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• Neuronal regeneration: Vertebrates comparative overview and new perspectives for neurodegenerative diseases

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  2021cites this paper
• Immunoreactivity for Dab2 and Foxp3 suggests that immune‐suppressive cells are present in the regenerating tail blastema of lizard

  2021cites this paper
• An introduction to an evolutionary tail: EvoDevo, structure and function of post-anal appendages.

  2021cites this paper
• The dendrite arbor of Purkinje cells is altered following to tail regeneration in the leopard gecko.

  2021cites this paper
• Future Tail Tales: A Forward-Looking, Integrative Perspective on Tail Research.

  2021cites this paper
• Tails of reproduction: Regeneration leads to increased reproductive investment.

  2021cites this paper
• Use it and bruise it: copulation rates are associated with muscle inflammation across anole lizard species

  2021cites this paper
• Cutaneous tactile sensitivity before and after tail loss and regeneration in the leopard gecko (Eublepharis macularius)

  2021cites this paper
• Review. Limb regeneration in lizards under natural and experimental conditions with considerations on the induction of appendages regeneration in amniotes.

  2021cites this paper
• When one tail isn't enough: abnormal caudal regeneration in lepidosaurs and its potential ecological impacts

  2020cites this paper
• The development of integument and muscle in regenerated tail of Tokay gecko (Gekko gecko Linnaeus, 1758)

  2020cites this paper
• Evolutionary bedfellows: Reconstructing the ancestral state of autotomy and regeneration.

  2020cites this paper
• Histological structure of nerve fiber and blood vessels in regenerated tail of Tokay gecko (Gekko gecko (Linnaeus, 1758)

  2020cites this paper
• Autoradiography and inmmunolabeling suggests that lizard blastema contains arginase-positive M2-like macrophages that may support tail regeneration.

  2020cites this paper
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  2020cites this paper
• Bilateral antler sequestration above the coronet in a red deer (Cervus elaphus) stag—Insights into the process of antler casting

  2020cites this paper
• FROM ORGANISMS TO ECOSYSTEMS: IMPACTS OF LIMB LOSS AND REGENERATION ON CRAYFISH BEHAVIOR

  2020cites this paper
• The nocturnal leopard gecko (Eublepharis macularius) uses UVb radiation for vitamin D3 synthesis.

  2020cites this paper
• The Tail of the Late Jurassic Sauropod Giraffatitan brancai: Digital Reconstruction of Its Epaxial and Hypaxial Musculature, and Implications for Tail Biomechanics

  2020cites this paper
• Re-regeneration to reduce negative effects associated with tail loss in lizards

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
• Nervous System Compensation Following Tail Loss and Regeneration in the Leopard Gecko (Eublepharis macularius)

  2019influential citation
• The ecology and evolution of autotomy

  2019cites this paper
• Tail regeneration in Lepidosauria as an exception to the generalized lack of organ regeneration in amniotes.

  2019cites this paper
• Vitamin A administration in lizards during tail regeneration determines epithelial mucogenesis and delays muscle and cartilage differentiation.

  2019cites this paper
• Immunolocalization of Wnts in the lizard blastema supports a key role of these signaling proteins for tail regeneration

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• Immunolabelling for RhoV and actin in early regenerating tail of the lizard Podarcis muralis suggests involvement in epithelial and mesenchymal cell motility

  2019cites this paper
• Microscopic observations on amputated and scarring lizard digits show an intense inflammatory reaction.

  2019cites this paper
• Review: The Regenerating Tail Blastema of Lizards as a Model to Study Organ Regeneration and Tumor Growth Regulation in Amniotes

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  2018cites this paper
• Msx1-2 immunolocalization in the regenerating tail of a lizard but not in the scarring limb suggests its involvement in the process of regeneration

  2018cites this paper
• Identification of satellite cells from anole lizard skeletal muscle and demonstration of expanded musculoskeletal potential.

  2018cites this paper
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  2018cites this paper
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  2018cites this paper
• Caudal autotomy as anti-predatory behaviour in Palaeozoic reptiles

  2018cites this paper
• Perspective: Appendage regeneration in amphibians and some reptiles derived from specific evolutionary histories.

  2018cites this paper
• Chapter 2 Regeneration : Lessons from the Lizard

  2018cites this paper
• Low‐cysteine alpha‐keratins and corneous beta‐proteins are initially formed in the regenerating tail epidermis of lizard

  2017cites this paper
• An energetic perspective on tissue regeneration: The costs of tail autotomy in growing geckos.

  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
• Tail regeneration and other phenomena of wound healing and tissue restoration in lizards

  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• Demografia e autotomia caudal de dois lagartos endêmicos de uma savana neotropical

  2016cites this paper
• Regeneration: Lessons from the Lizard

  2016cites this paper
• Genetics and Regeneration in Vertebrates

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• Innovations in Molecular Mechanisms and Tissue Engineering

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2015cites this paper
• The regeneration blastema of lizards: an amniote model for the study of appendage replacement

  2015cites this paper
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  2015cites this paper
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  2015cites this paper