Endocytosis and Synaptic Function

Abstract Most Parkinsons disease (PD) cases are sporadic; however, about 10% of PD cases are inherited and many of the genes that are causative for these inherited cases are known. There is evidence that many of these genes play an essential role in the maintenance of normal presynaptic function. Mutations and sometimes overexpression of certain PD-causing genes lead to synaptic transmission defects and such defects may potentially lead to neurodegeneration. In this book chapter we present an overview of essential synaptic processes and link them to the PD genes that are thought to play a role in these synaptic processes.

• Publication year

  2017

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/B978-0-12-803783-6.00007-9
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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