Mesenchymal Stem Cell Injection Induces Cardiac Nerve Sprouting and Increased Tenascin Expression in a Swine Model of Myocardial Infarction

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Cardiovascular Electrophysiology

• Publication date

  2003-08-01

• Fields of study

  Medicine, Engineering

• Identifiers
  DOI 10.1046/j.1540-8167.2003.03124.xPMID 12890047
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction.

  2003cited by this paper
• Mesenchymal stem cell therapy prevents deterioration of left ventricular function in a porcine myocardial infarction model

  2002cited by this paper
• Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects.

  2002cited by this paper
• Bone marrow cells regenerate infarcted myocardium

  2001cited by this paper
• Nerve Sprouting and Sympathetic Hyperinnervation in a Canine Model of Atrial Fibrillation Produced by Prolonged Right Atrial Pacing

  2001cited by this paper
• Adventitial remodeling after angioplasty is associated with expression of tenascin mRNA by adventitial myofibroblasts.

  2001cited by this paper
• Arrhythmogenesis and Contractile Dysfunction in Heart Failure: Roles of Sodium-Calcium Exchange, Inward Rectifier Potassium Current, and Residual &bgr;-Adrenergic Responsiveness

  2001cited by this paper
• Modulation of QT Interval by Cardiac Sympathetic Nerve Sprouting and the Mechanisms of Ventricular Arrhythmia in a Canine Model of Sudden Cardiac Death

  2001cited by this paper
• The structure and function of tenascins in the nervous system.

  2001cited by this paper
• Neovascularization of ischemic myocardium by human bone-marrow–derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function

  2001cited by this paper
• Tenascin‐R is expressed by Schwann cells in the peripheral nervous system

  2001cited by this paper
• Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental myocardial ischemia.

  2001cited by this paper
• Adult rat and human bone marrow stromal cells differentiate into neurons

  2000cited by this paper
• Mesenchymal stem cells: biology and potential clinical uses.

  2000cited by this paper
• Atrial fibrillation produced by prolonged rapid atrial pacing is associated with heterogeneous changes in atrial sympathetic innervation.

  2000cited by this paper
• Cell transplantation as future therapy for cardiovascular disease?: A workshop of the National Heart, Lung, and Blood Institute.

  2000cited by this paper
• Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages.

  2000cited by this paper
• Colocalization of Tenascin and Sympathetic Nerves in a Canine Model of Nerve Sprouting and Sudden Cardiac Death

  2000cited by this paper
• Relationship between regional cardiac hyperinnervation and ventricular arrhythmia.

  2000cited by this paper
• Nerve sprouting and sudden cardiac death.

  2000cited by this paper
• Induction of Tenascin-C in Cardiac Myocytes by Mechanical Deformation

  1999cited by this paper
• Cardiomyocytes can be generated from marrow stromal cells in vitro.

  1999cited by this paper
• Angiogenesis and expression of tenascin after transmural laser revascularization.

  1999cited by this paper
• Autologous transplantation of bone marrow cells improves damaged heart function.

  1999cited by this paper
• Tenascin-C is expressed in macrophage-rich human coronary atherosclerotic plaque.

  1999cited by this paper
• Regression of hypertrophied rat pulmonary arteries in organ culture is associated with suppression of proteolytic activity, inhibition of tenascin-C, and smooth muscle cell apoptosis.

  1999cited by this paper
• Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections.

  1991cited by this paper
• Dispersion of refractoriness in canine ventricular myocardium. Effects of sympathetic stimulation.

  1991cited by this paper
• Nerve Growth Factor: Increased Angiogenesis without Improved Nerve Regeneration

  1991cited by this paper
• Fate of nerve fibers in necrotic, healing, and healed rat myocardium.

  1990cited by this paper
• Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones.

  1986cited by this paper
• Effects of Sympathetic and Vagal Nerves on Recovery Properties of the Endocardium and Epicardium of the Canine Left Ventricle

  1980cited by this paper

• Exosomes and Their Bioengineering Strategies in the Cutaneous Wound Healing and Related Complications: Current Knowledge and Future Perspectives

  2023cites this paper
• Direct Cardiac Reprogramming: Current Status and Future Prospects.

  2023cites this paper
• Cardiac sympathetic hyperinnervation after myocardial infarction: a systematic review and qualitative analysis

  2023influential citation
• Tenascin-C as a noninvasive biomarker of coronary artery disease

  2022cites this paper
• Toxicological Profile of Umbilical Cord Blood-Derived Small Extracellular Vesicles

  2021cites this paper
• Conditioned Medium Harvested from Hif1α Engineered Mesenchymal Stem cells Ameliorates LAD-Occlusion -Induced Injury in Rat Acute Myocardial Ischemia Model.

  2020cites this paper
• The Application of MSCs-Derived Extracellular Vesicles in Bone Disorders: Novel Cell-Free Therapeutic Strategy

  2020cites this paper
• Xenogeneic and Stem Cell-Based Therapy for Cardiovascular Diseases: Genetic Engineering of Porcine Cells and Their Applications in Heart Regeneration

  2020cites this paper
• Bone marrow mesenchymal stem cell-derived exosomes protect against myocardial infarction by promoting autophagy

  2019cites this paper
• Applications of stem cells and bioprinting for potential treatment of diabetes

  2019cites this paper
• 58 – Cardiac Repair With Human Pluripotent Stem Cell–Derived Cardiovascular Cells and Arrhythmia Risk

  2018cites this paper
• MSC exosome works through a protein-based mechanism of action

  2018cites this paper
• Efficient scalable production of therapeutic microvesicles derived from human mesenchymal stem cells

  2018cites this paper
• Remote preconditioning: Evaluating the efficacy of cardioprotection in type-2 diabetes and exploring the mechanistic role of exosomes

  2017cites this paper
• Serum-Free Xenogen-Free Culture Conditions Support Human Explant-Derived Cardiac Stem Cell Growth

  2017cites this paper
• MSC exosome as a cell-free MSC therapy for cartilage regeneration: Implications for osteoarthritis treatment.

  2017cites this paper
• Targeting the pathway of GSK-3β/nerve growth factor to attenuate post-infarction arrhythmias by preconditioned adipose-derived stem cells.

  2017cites this paper
• Restoring heart function and electrical integrity: closing the circuit

  2017cites this paper
• Modeling Electrophysiological Coupling and Fusion between Human Mesenchymal Stem Cells and Cardiomyocytes

  2016cites this paper
• Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease

  2016cites this paper
• Mesenchymal stromal cell extracellular vesicles/exosomes

  2016cites this paper
• Research Advancements in Porcine Derived Mesenchymal Stem Cells

  2016cites this paper
• Miniature Swine for Preclinical Modeling of Complexities of Human Disease for Translational Scientific Discovery and Accelerated Development of Therapies and Medical Devices

  2016cites this paper
• Role of Stem Cells in Cardiac Diseases

  2016cites this paper
• Antiarrhythmic effect of growth factor-supplemented cardiac progenitor cells in chronic infarcted heart.

  2016cites this paper
• A New In Vitro Co‐Culture Model Using Magnetic Force‐Based Nanotechnology

  2016cites this paper
• Electrical effects of stem cell transplantation for ischaemic cardiomyopathy: friend or foe?

  2016cites this paper
• Is it Arrhythmogenic?*

  2016cites this paper
• Stem Cells Transplantation in Myocardial Tissue Induces Pro- Arrhythmic Effects and Promotes 4 Reperfusion. Comparison between Intramyocardial and Intravenous Approach

  2015cites this paper
• Arrhythmia in stem cell transplantation.

  2015cites this paper
• Growth factor and small molecule influence on urological tissue regeneration utilizing cell seeded scaffolds.

  2015cites this paper
• A novel high throughput approach to screen for cardiac arrhythmic events following stem cell treatment.

  2015cites this paper
• Mesenchymal Stem Cells Improve Heart Rate Variability and Baroreflex Sensitivity in Rats with Chronic Heart Failure

  2015cites this paper
• Pancreas and Spleen

  2015cites this paper
• Transplantation of adipose tissue-derived stem cells improves cardiac contractile function and electrical stability in a rat myocardial infarction model.

  2015cites this paper
• Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications.

  2015cites this paper
• 41 – Sympathetic Innervation, Denervation, and Cardiac Arrhythmias

  2014cites this paper
• Mesenchymal stem cells enhanced cardiac nerve sprouting via nerve growth factor in a rat model of myocardial infarction.

  2014cites this paper
• Electrical Integration of Human Embryonic Stem Cell-Derived Cardiomyocytes in a Guinea Pig Chronic Infarct Model

  2014cites this paper
• Antiarrhythmic versus Arrhythmogenic Potentials of Mesenchymal Stem Cells , Paracrine Factors , and Cardiogenic Cells

  2014cites this paper
• Stem Cells of the Apical Papilla Regulate Trigeminal Neurite Outgrowth and Targeting through a BDNF-Dependent Mechanism

  2014cites this paper
• Stem cells can form gap junctions with cardiac myocytes and exert pro-arrhythmic effects

  2014cites this paper
• 57 – Cell Therapy and Regenerative Electrophysiology

  2014cites this paper
• Exosome: A Novel and Safer Therapeutic Refinement of Mesenchymal Stem Cell

  2013cites this paper
• Mesenchymal Stem Cell Exosomes: The Future MSC-Based Therapy?

  2013cites this paper
• [Mesenchymal stem cell therapy in heart disease].

  2013cites this paper
• Effect of transplantation with autologous bone marrow stem cells on acute myocardial infarction.

  2013cites this paper
• Mesenchymal stem cell therapy in heart disease

  2013cites this paper
• Exosomes and Microvesicles Exosome: A Novel and Safer Therapeutic Refinement of Mesenchymal Stem Cell

  2013cites this paper
• Antiarrhythmic potential of mesenchymal stem cell is modulated by hypoxic environment.

  2012cites this paper
• Soluble Factors from Multipotent Mesenchymal Stromal Cells have Antinecrotic Effect on Cardiomyocytes in Vitro and Improve Cardiac Function in Infarcted Rat Hearts

  2012cites this paper
• Kardiomyogene Differenzierungspotenz und Wachstumskinetik von adulten humanen mesenchymalen Stammzellen

  2012cites this paper
• Lack of Cardiac Nerve Sprouting after Intramyocardial Transplantation of Bone Marrow-Derived Stem Cells in a Swine Model of Chronic Ischemic Myocardium

  2012influential citation
• Mesenchymal stem cells neither fully acquire the electrophysiological properties of mature cardiomyocytes nor promote ventricular arrhythmias in infarcted rats

  2012cites this paper
• Human adipose tissue derived mesenchymal stem cells are resistant to several chemotherapeutic agents

  2011cites this paper
• The proarrhythmic risk of cell therapy for cardiovascular diseases

  2011cites this paper
• Growth Factor-Induced Mobilization of Cardiac Progenitor Cells Reduces the Risk of Arrhythmias, in a Rat Model of Chronic Myocardial Infarction

  2011cites this paper
• Mesenchymal stem cell injection ameliorates the inducibility of ventricular arrhythmias after myocardial infarction in rats.

  2011cites this paper
• Intracoronary delivery of mesenchymal stem cells reduces proarrhythmogenic risks in swine with myocardial infarction

  2011cites this paper
• Large animal models for cardiac stem cell therapies.

  2011cites this paper
• Repair mechanisms of bone marrow mesenchymal stem cells in myocardial infarction

  2011cites this paper
• Toward an ideal animal model to trace donor cell fates after stem cell therapy: production of stably labeled multipotent mesenchymal stem cells from bone marrow of transgenic pigs harboring enhanced green fluorescence protein gene.

  2011cites this paper
• The role of tenascin C in cardiovascular disease.

  2011cites this paper
• Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease.

  2011cites this paper
• Myocardial Repair and Restoration

  2011cites this paper
• DI RICERCA IN “ FISIOPATOLOGIA SISTEMICA ” ( XXII ciclo ) ELECTRICAL COMPETENCE OF THE INFARCTED HEART FOLLOWING STEM CELL BASED REGENERATIVE THERAPY , IN A RAT MODEL

  2011cites this paper
• Les cellules souches mésenchymateuses dans les maladies dysimmunitaires

  2011cites this paper
• Les cellules souches mésenchymateuses de moelle osseuse et du tissu adipeux en médecine régénératrice cardiovasculaire

  2011cites this paper
• Biology and Therapeutic Use of Domestic Animal Stem Cells Large animal models for cardiac stem cell therapies

  2011cites this paper
• Collagen scaffolds and injectable biopolymer gels for cardiac tissue engineering

  2011cites this paper
• Gene expression pattern in rat bone marrow mesenchymal stem cells in response to hypoxia

  2010cites this paper
• Neural differentiation and therapeutic potential of adipose tissue derived stem cells.

  2010cites this paper
• Cardiac cell therapy with mesenchymal stem cell induces cardiac nerve sprouting, angiogenesis, and reduced connexin43-positive gap junctions, but concomitant electrical pacing increases connexin43-positive gap junctions in canine heart

  2010cites this paper
• Current Perspectives on Imaging Cardiac Stem Cell Therapy

  2010cites this paper
• Regeneration potential and survival of transplanted undifferentiated adipose tissue-derived stem cells in peripheral nerve conduits.

  2010cites this paper
• The arrythmogenic potential of post-myocardial infarction cytokine treatment.

  2009cites this paper
• Electrophysiological challenges of cell-based myocardial repair.

  2009cites this paper
• Mesenchymal stem cells for the heart

  2009cites this paper
• Granulocyte colony-stimulating factor increases sympathetic reinnervation and the arrhythmogenic response to programmed electrical stimulation after myocardial infarction in rats.

  2009cites this paper
• Porcine mesenchymal stem cells--current technological status and future perspective.

  2009influential citation
• Stem Cells Are Not Proarrhythmic: Letting the Genie out of the Bottle

  2009cites this paper
• Stem cell therapy for heart failure: are arrhythmias a real safety concern?

  2009cites this paper
• The effects of intracoronary autologous mononuclear bone marrow cell transplantation on cardiac arrhythmia and heart rate variability.

  2009cites this paper
• IFATS Collection: Human Adipose Tissue‐Derived Stem Cells Induce Angiogenesis and Nerve Sprouting Following Myocardial Infarction, in Conjunction with Potent Preservation of Cardiac Function

  2009cites this paper
• Utilization of MSCs for Repairing Cardiomyocytes

  2009cites this paper
• Transdifferentiation of stem cells: a critical view.

  2009cites this paper
• Feasibility of MSCs Transplantaion

  2009cites this paper
• electrical stimulation after sympathetic reinnervation and the arrhythmogenic Granulocyte colony-stimulating factor increases

  2009cites this paper
• Indirect co-culture with tenocytes promotes proliferation and mRNA expression of tendon/ligament related genes in rat bone marrow mesenchymal stem cells

  2009cites this paper
• The role of the autonomic nervous system in sudden cardiac death.

  2008cites this paper
• Enhancing Efficacy of Stem Cell Transplantation to the Heart with a PEGylated Fibrin Biomatrix

  2008cites this paper
• Stem cell therapy in myocardial repair and remodeling.

  2008cites this paper
• Cell therapy for cardiac repair.

  2008cites this paper
• Cell Transplantation Therapy for Myocardial Repair: Current Status and Future Challenges

  2008cites this paper
• Human Mesenchymal Stem Cell Transplantation Induces Sympathetic Nerve Sprouting and Reduces the Gap Junction With Potential Proarrhythmias in Dogs

  2008cites this paper
• Various Cell Types with Cardiomyogenic Differentia ell type Source nfractionated bone marrow cells Bone marrow c S ematopoetic stem cells Bone marrow Umbilical cord blood C C esenchymal stem cells Bone marrow Umbilical cord blood Adipose tissue

  2008cites this paper
• Terapia cellulare e aritmie: il punto della situazione

  2008cites this paper
• Concise Review: Mesenchymal Stromal Cells: Potential for Cardiovascular Repair

  2008cites this paper
• Cellular replacement therapy for arrhythmia treatment: Early clinical experience

  2008cites this paper
• Transcriptional profiling of young and old mesenchymal stem cells in response to oxygen deprivation and reparability of the infarcted myocardium.

  2008cites this paper