Experimental models to investigate the function of dendritic cell subsets: challenges and implications

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Clinical and Experimental Immunology

• Publication date

  2013-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/cei.12027PMID 23286941PMCID PMC3573285
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• CD8α+ and CD8α− DC subsets from BCG‐infected mice inhibit allergic Th2‐cell responses by enhancing Th1‐cell and Treg‐cell activity respectively

  2012cited by this paper
• Langerhans Cells Require MyD88-Dependent Signals for Candida albicans Response but Not for Contact Hypersensitivity or Migration

  2012cited by this paper
• Dendritic cell‐associated lectin 2 (DCAL2) defines a distinct CD8α− dendritic cell subset

  2012cited by this paper
• Functionally relevant neutrophilia in CD11c diphtheria toxin receptor transgenic mice

  2012cited by this paper
• Conditional ablation of CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo

  2012cited by this paper
• Characterization of resident and migratory dendritic cells in human lymph nodes

  2012cited by this paper
• The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity.

  2011cited by this paper
• Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses.

  2011cited by this paper
• Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A

  2011cited by this paper
• Pulmonary CD103+ dendritic cells prime Th2 responses to inhaled allergens

  2011cited by this paper
• TLR7 enables cross-presentation by multiple dendritic cell subsets through a type I IFN-dependent pathway.

  2011cited by this paper
• Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation.

  2011cited by this paper
• Langerhans cells are precommitted to immune tolerance induction

  2011cited by this paper
• Applications of myeloid‐specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity

  2011cited by this paper
• Targeting Antigen to Mouse Dendritic Cells via Clec9A Induces Potent CD4 T Cell Responses Biased toward a Follicular Helper Phenotype

  2011cited by this paper
• Endogenous lectins shape the function of dendritic cells and tailor adaptive immunity: mechanisms and biomedical applications.

  2011cited by this paper
• Batf3-Dependent CD11blow/− Peripheral Dendritic Cells Are GM-CSF-Independent and Are Not Required for Th Cell Priming after Subcutaneous Immunization

  2011cited by this paper
• Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8−CD11b+ dendritic cells

  2011cited by this paper
• Id2 expression delineates differential checkpoints in the genetic program of CD8α+ and CD103+ dendritic cell lineages

  2011cited by this paper
• Defining dendritic cells by conditional and constitutive cell ablation

  2010cited by this paper
• CD8+ T Cell Priming by Dendritic Cell Vaccines Requires Antigen Transfer to Endogenous Antigen Presenting Cells

  2010cited by this paper
• Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8+ T cell responses to influenza

  2010cited by this paper
• Dendritic Cells Support Homeostatic Expansion of Foxp3+ Regulatory T Cells in Foxp3.LuciDTR Mice

  2010cited by this paper
• Differentiation of effector CD4 T cell populations (*).

  2010cited by this paper
• Endogenous dendritic cells mediate the effects of intravenously injected therapeutic immunosuppressive dendritic cells in transplantation.

  2010cited by this paper
• Dendritic Cell (DC)-Specific Targeting Reveals Stat3 as a Negative Regulator of DC Function

  2010cited by this paper
• Found in translation: the human equivalent of mouse CD8+ dendritic cells

  2010cited by this paper
• Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A

  2010cited by this paper
• Route of Antigen Uptake Differentially Impacts Presentation by Dendritic Cells and Activated Monocytes

  2010cited by this paper
• Mechanisms regulating dendritic cell specification and development

  2010cited by this paper
• Tonic T cell signalling and T cell tolerance as opposite effects of self-recognition on dendritic cells.

  2010cited by this paper
• Subsets of migrating intestinal dendritic cells

  2010cited by this paper
• A novel in vivo inducible dendritic cell ablation model in mice.

  2010cited by this paper
• Comparative genomics as a tool to reveal functional equivalences between human and mouse dendritic cell subsets

  2010cited by this paper
• Features of the dendritic cell lineage

  2010cited by this paper
• DC subsets in positive and negative regulation of immunity

  2010cited by this paper
• Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations.

  2010cited by this paper
• A role for CD47 in the development of experimental colitis mediated by SIRPα+CD103− dendritic cells

  2009cited by this paper
• Distinctive localization of antigen-presenting cells in human lymph nodes.

  2009cited by this paper
• Langerin+CD8α+ Dendritic Cells Are Critical for Cross-Priming and IL-12 Production in Response to Systemic Antigens1

  2009cited by this paper
• Lymphoid-tissue-specific homing of bone-marrow-derived dendritic cells.

  2009cited by this paper
• In Situ-Targeting of Dendritic Cells with Donor-Derived Apoptotic Cells Restrains Indirect Allorecognition and Ameliorates Allograft Vasculopathy

  2009cited by this paper
• Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

  2009cited by this paper
• Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin.

  2008cited by this paper
• Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

  2008cited by this paper
• Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity

  2008cited by this paper
• Lack of conventional dendritic cells is compatible with normal development and T cell homeostasis, but causes myeloid proliferative syndrome.

  2008cited by this paper
• Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset

  2008cited by this paper
• CD11c+CD11b+ Dendritic Cells Play an Important Role in Intravenous Tolerance and the Suppression of Experimental Autoimmune Encephalomyelitis1

  2008cited by this paper
• Migratory and lymphoid-resident dendritic cells cooperate to efficiently prime naive CD4 T cells.

  2008cited by this paper
• CD8– dendritic cells preferentially cross‐present Saccharomyces cerevisiae antigens

  2008cited by this paper
• Epidermal and Dermal Dendritic Cells Display Differential Activation and Migratory Behavior While Sharing the Ability to Stimulate CD4+ T Cell Proliferation In Vivo12

  2008cited by this paper
• Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation.

  2007cited by this paper
• CD8− DCs induce IL-12–independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS

  2007cited by this paper
• Temporal Regulation of Interleukin-12p70 (IL-12p70) and IL-12-Related Cytokines in Splenic Dendritic Cell Subsets during Leishmania donovani Infection

  2007cited by this paper
• Noncognate Interaction with MHC Class II Molecules Is Essential for Maintenance of T Cell Metabolism to Establish Optimal Memory CD4 T Cell Function1

  2007cited by this paper
• A subset of dendritic cells induces CD4+ T cells to produce IFN-γ by an IL-12–independent but CD70-dependent mechanism in vivo

  2007cited by this paper
• Notch–RBP-J signaling controls the homeostasis of CD8− dendritic cells in the spleen

  2007cited by this paper
• MHC class II deprivation impairs CD4 T cell motility and responsiveness to antigen-bearing dendritic cells in vivo

  2007cited by this paper
• Skin-Derived Dendritic Cells Can Mediate Deletional Tolerance of Class I-Restricted Self-Reactive T Cells1

  2007cited by this paper
• Anatomic location defines antigen presentation by dendritic cells to T cells in response to intravenous soluble antigens

  2007cited by this paper
• In vivo magnetic resonance imaging of dendritic cell migration into the draining lymph nodes of mice

  2006cited by this paper
• Self-recognition is crucial for maintaining the peripheral CD4+ T-cell pool in a nonlymphopenic environment.

  2006cited by this paper
• Langerhans cells cross-present antigen derived from skin

  2006cited by this paper
• Induction of CD8+ T cell responses through targeting of antigen to Dectin-2.

  2006cited by this paper
• Preferential Induction of CD4+ T Cell Responses through In Vivo Targeting of Antigen to Dendritic Cell-Associated C-Type Lectin-1

  2006cited by this paper
• Non-invasive imaging of dendritic cell migration in vivo.

  2006cited by this paper
• Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity

  2005cited by this paper
• CD8alpha-11b+ dendritic cells but not CD8alpha+ dendritic cells mediate cross-tolerance toward intestinal antigens.

  2005cited by this paper
• Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells.

  2005cited by this paper
• Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity.

  2005cited by this paper
• Histological analysis of CD11c‐DTR/GFP mice after in vivo depletion of dendritic cells

  2005cited by this paper
• CD8α–11b+ dendritic cells but not CD8α+ dendritic cells mediate cross-tolerance toward intestinal antigens

  2005cited by this paper
• IFN Regulatory Factor-4 and -8 Govern Dendritic Cell Subset Development and Their Functional Diversity

  2005cited by this paper
• Differential capacity of CD8α+ or CD8α− dendritic cell subsets to prime for eosinophilic airway inflammation in the T‐helper type 2‐prone milieu of the lung

  2004cited by this paper
• T cell activation: in vivo veritas

  2004cited by this paper
• Endogenous Dendritic Cells Are Required for Amplification of T Cell Responses Induced by Dendritic Cell Vaccines In Vivo 1

  2003cited by this paper
• Analysis of dendritic cell trafficking using EGFP-transgenic mice.

  2003cited by this paper
• The ability of murine dendritic cell subsets to direct T helper cell differentiation is dependent on microbial signals

  2003cited by this paper
• Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells.

  2003cited by this paper
• Flexibility of Mouse Classical and Plasmacytoid-derived Dendritic Cells in Directing T Helper Type 1 and 2 Cell Development

  2003cited by this paper
• Epidermal Viral Immunity Induced by CD8α+ Dendritic Cells But Not by Langerhans Cells

  2003cited by this paper
• TH2 dominance and defective development of a CD8+ dendritic cell subset in Id2-deficient mice.

  2003cited by this paper
• Vaginal Submucosal Dendritic Cells, but Not Langerhans Cells, Induce Protective Th1 Responses to Herpes Simplex Virus-2

  2003cited by this paper
• Langerhans cells renew in the skin throughout life under steady-state conditions

  2003cited by this paper
• CD4+ T Cells Pass Through an Effector Phase During the Process of In Vivo Tolerance Induction

  2003cited by this paper
• Experimental models linking dendritic cell lineage, phenotype and function

  2002cited by this paper
• Constitutive versus Activation-dependent Cross-Presentation of Immune Complexes by CD8+ and CD8− Dendritic Cells In Vivo

  2002cited by this paper
• Langerhans cells renew in the skin throughout life under steady-state conditions

  2002cited by this paper
• Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

  2002cited by this paper
• IL-12 Induction by a Th1-Inducing Adjuvant In Vivo: Dendritic Cell Subsets and Regulation by IL-10

  2001cited by this paper
• Induction of CTL and Nonpolarized Th Cell Responses by CD8α+ and CD8α− Dendritic Cells1

  2001cited by this paper
• CD4+ T cell survival is not directly linked to self-MHC–induced TCR signaling

  2000cited by this paper
• CD8α+ and CD8α− Subclasses of Dendritic Cells Direct the Development of Distinct T Helper Cells In Vivo

  1999cited by this paper
• Carboxyfluorescein diacetate succinimidyl ester and the virgin lymphocyte: A marriage made in heaven

  1999cited by this paper
• Distinct dendritic cell subsets differentially regulate the class of immune response in vivo.

  1999cited by this paper
• Antigen-pulsed CD8α+ Dendritic Cells Generate an Immune Response after Subcutaneous Injection without Homing to the Draining Lymph Node

  1999cited by this paper
• The evolution of self-tolerance: a new cell arises to meet the challenge of self-reactivity.

  1998cited by this paper
• Dendritic cell subtypes in mouse lymphoid organs: cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes.

  1997cited by this paper
• Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo

  1996cited by this paper

• The Immune-Modulatory Properties of iPSC-Derived Antigen-Presenting Cells

  2020cites this paper
• Computational Prediction and Validation of Tumor-Associated Neoantigens

  2020cites this paper
• Characterization of humoral and cellular immune features of gamma-irradiated influenza vaccine

  2020cites this paper
• Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins

  2020cites this paper
• Intracellular NOD2 Activation Promotes Maturation and Antigen-Presenting Functions of Dentritic Cells Exposed to Porphyromonas Gingivalis Lipopolysaccharide.

  2018cites this paper
• The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation

  2018cites this paper
• The role of dendritic cells in immune regulation of nasal polyps.

  2017cites this paper
• Differential roles of Porphyromonas gingivalis lipopolysaccharide and Escherichia coli lipopolysaccharide in maturation and antigen-presenting functions of dentritic cells.

  2015cites this paper
• Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation

  2014cites this paper
• Extracorporeal Photopheresis: Scientific and Technical Considerations for Improving Clinical Management of Patients

  2014cites this paper
• A Systems Biology Approach to the Analysis of Subset-Specific Responses to Lipopolysaccharide in Dendritic Cells

  2014cites this paper