Roles of Ghrelin and Leptin in the Control of Reproductive Function

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Neuroendocrinology

• Publication date

  2007-09-12

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1159/000108410PMID 17851226
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Exploring the role of ghrelin as novel regulator of gonadal function.

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• Direct in vivo effects of leptin on ovarian steroidogenesis in sheep.

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• Recombinant human leptin in women with hypothalamic amenorrhea.

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• Ghrelin inhibits the proliferative activity of immature Leydig cells in vivo and regulates stem cell factor messenger ribonucleic acid expression in rat testis.

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• Endocrine and metabolic effects of physiologic r-metHuLeptin administration during acute caloric deprivation in normal-weight women.

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• Direct Effects of Leptin on Mouse Reproductive Function: Regulation of Follicular, Oocyte, and Embryo Development

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• Decrease in luteinizing hormone pulse frequency during a five-hour peripheral ghrelin infusion in the ovariectomized rhesus monkey.

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• Recombinant human leptin in women with hypothalamic amenorrhea.

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• Cellular distribution and regulation of ghrelin messenger ribonucleic acid in the rat pituitary gland.

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• Ontogenesis of Leptin Receptor in Rat Leydig Cells1

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• Ghrelin, a widespread hormone: insights into molecular and cellular regulation of its expression and mechanism of action

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• Cellular Location and Hormonal Regulation of Ghrelin Expression in Rat Testis1

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• Expression of Leptin and Its Receptor in the Murine Ovary: Possible Role in the Regulation of Oocyte Maturation1

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• Novel Expression and Functional Role of Ghrelin in Rat Testis.

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• Leptin directly acts within the hypothalamus to stimulate gonadotropin‐releasing hormone secretion in vivo in rats

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• Leptin and Ovarian Folliculogenesis: Implications for Ovulation Induction and ART Outcomes

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• Leptin in male reproduction: the testis paradigm.

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• Expression of the long (OB-RB) and short (OB-RA) forms of the leptin receptor throughout the oestrous cycle in the mature rat ovary.

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• The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans.

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• Novel expression and functional role of ghrelin in rat testis.

  2002cited by this paper
• Intracerebroventricular administration of ghrelin rapidly suppresses pulsatile luteinizing hormone secretion in ovariectomized rats.

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• Developmental and Hormonal Regulation of Leptin Receptor (Ob-R) Messenger Ribonucleic Acid Expression in Rat Testis1

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• Leptin in reproduction.

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• Leptin inhibits steroid biosynthesis by human granulosa-lutein cells.

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• Inhibitory Action of Leptin on Early Follicular Growth Differs in Immature and Adult Female Mice

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• A Reassessment of Leptin’s Role in Triggering the Onset of Puberty in the Rat and Mouse

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• Evidence of leptin expression in normal and polycystic human ovaries.

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• Ghrelin, a novel placental-derived hormone.

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• Molecular mechanisms of leptin action in adult rat testis: potential targets for leptin-induced inhibition of steroidogenesis and pattern of leptin receptor messenger ribonucleic acid expression.

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• Testis-specific and developmentally induced expression of a ghrelin gene-derived transcript that encodes a novel polypeptide in the mouse.

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• Leptin regulation of neuroendocrine systems.

  2000cited by this paper
• In vitro pituitary and testicular effects of the leptin-related synthetic peptide leptin(116-130) amide involve actions both similar to and distinct from those of the native leptin molecule in the adult rat.

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• Human leptin: from an adipocyte hormone to an endocrine mediator.

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• Neuroendocrine Regulation of Pituitary Function

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• The in vivo and in vitro effects of exogenous leptin on ovulation in the rat.

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• Leptin inhibits testosterone secretion from adult rat testis in vitro.

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• Printed in U.S.A. Copyright © 2000 by The Endocrine Society Expression of the Leptin Receptor during Germ Cell Development in the Mouse Testis*

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• Expression of functional leptin receptors in rodent Leydig cells.

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• Leptin116–130 Stimulates Prolactin and Luteinizing Hormone Secretion in Fasted Adult Male Rats

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• Evidence for GnRH Regulation by Leptin: Leptin Administration Prevents Reduced Pulsatile LH Secretion during Fasting

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• Inverse correlation between serum testosterone and leptin in men.

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• Leptin: a molecule integrating somatic energy stores, energy expenditure and fertility.

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• Early Onset of Reproductive Function in Normal Female Mice Treated with Leptin

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• Leptin treatment rescues the sterility of genetically obese ob/ob males.

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• Direct Intraovarian Effects of Leptin: Impairment of the Synergistic Action of Insulin-Like Growth Factor-I on Follicle-Stimulating Hormone-Dependent Estradiol-17β Production by Rat Ovarian Granulosa Cells.

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